{"title":"[Wat ondeugd ons leert over professionaliteit].","authors":"J A Godschalx-Dekker, W N K A van Mook","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 3","pages":"157-158"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Cools, O Jennen, S Lambrichts, K Vansteelandt, P Sienaert
{"title":"[Relapse in psychotic depression and comparison with non-psychotic depression].","authors":"L Cools, O Jennen, S Lambrichts, K Vansteelandt, P Sienaert","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Psychotic depression (PD) is a severe disease with a lifetime prevalence between 0.35 and 1%. The guidelines recommend combination therapy with an antidepressant and an antipsychotic, whereas in non-psychotic depression (NPD) an antidepressant is advised as monotherapy.</p><p><strong>Aim: </strong>To determine whether there is a difference in relapse rates between PD and NPD, and which treatment is associated with the lowest relapse rate.</p><p><strong>Methods: </strong>A systematic literature search across 6 databases (PubMed, Web of Science, Scopus, Embase, Cochrane, and CINAHL) and a meta-analysis were conducted to compare relapse rates between PD and NPD.</p><p><strong>Results: </strong>Eight studies with a total of 468 patients and 147 relapse events were included in the meta-analysis. No statistically significant difference could be demonstrated in relapse rates between PD and NPD. The difference in relapse rates in PD between various treatments was not statistically analyzed, but qualitatively described. There was a wide variation in treatment methods and a broad range of relapse rates.</p><p><strong>Conclusions: </strong>Based on our findings, there is no statistically significant difference in relapse rates between patients with PD and NPD. However, caution is warranted with this conclusion, as the meta-analysis is based on a limited number of studies with high variability in the outcome measure. It seems important to continue acute treatment after response or remission, but which treatment modality best prevents relapse remains unclear.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 3","pages":"175-183"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Neurosteroids as treatment of postpartum depression: a critical literature review].","authors":"J Sondervan, A Hostens, G Lemmens","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Brexanolone (Zulresso) and zuranolone (Zurzuvae) are two synthetic neuroactive steroids that were approved by the U.S. Food and Drug Administration in March 2019 (as an intravenous treatment) and August 2023 (as an oral treatment) respectively, for the treatment of postpartum depression. To date, these products are not available in Belgium and The Netherlands.</p><p><strong>Aim: </strong>To evaluate the effectiveness and side effects of brexanolone and zuranolone in the treatment of postpartum depression through the evaluation of previous double-blind placebo-controlled trials.</p><p><strong>Method: </strong>A clinically oriented literature study.</p><p><strong>Results: </strong>Brexanolone and zuranolone are effective in the treatment of postpartum depression with a clinically significant rapid response compared to placebo. The main reported side effects are dizziness, somnolence, and sedation.</p><p><strong>Conclusion: </strong>Placebo-controlled studies support the effectiveness of treatment with brexanolone and zuranolone in postpartum depression, showing a rapid and statistically significant improvement in mood symptoms. However, the place of neurosteroids in practice is still unclear and needs to be clarified by future research and clinical experience.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 1","pages":"15-19"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Towards a future-proof psychotherapy: some recommendations].","authors":"W J M W Cuijpers","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Mental health care has improved considerably over the past decades, maar there are also still too many people who do not get better or too late.</p><p><strong>Results: </strong>In order to further improve psychological treatments, we can do several things. We can do more research on mechanisms of change, develop interventions that are scalable (for use in low- and middle-income countries), and we can personalize treatments with innovative machine learning techniques and ‘individual patient data’ (network) meta-analyses. We should not develop new general therapies, because they are typically not better than the ones that already existed. We should develop new therapies for more complex problems, like chronic conditions and comorbid disorders. We should also think of sequential treatments because many patients do not respond after the first treatment.</p><p><strong>Conclusion: </strong>If we could make all these improvements, we could much faster provide treatments to patients to which they respond, we could reduce drop-out and make mental health care much more efficient.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 2","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Later is too late: why psychiatrists must take action today for patients and the climate].","authors":"D S Everaerd, P Lagerweij, L Klok, J Zinkstok","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Climate change is a pressing issue, with significant effects also in Europe. In particular younger generations will face negative consequences of climate change, including impact on mental health. Therefore, climate change is relevant to psychiatrists.</p><p><strong>Aim: </strong>In this article, we explain how climate change leads to mental health problems and what psychiatrists can do.</p><p><strong>Method: </strong>Overview based on a recent European position paper on the consequences of climate change for mental health and recent literature RESULTS: Climate change leads to mental health problems on multiple levels: through direct consequences of disasters (for example, traumatization), as well as the effects of heat on mental health and adverse effects on social and societal determinants of mental health. These effects are most likely greatest in non-Western countries, where resources are limited. Additionally, there are mental complaints due to an increase in climate anxiety, especially among young people.</p><p><strong>Conclusion: </strong>We call on the field of psychiatry to increase and share interdisciplinary knowledge and take actions to prepare for the consequences of climate change. Actions are needed at multiple levels including preparing direct patient care for effects of climate change (e.g., preparing for heatwaves), reducing further climate change (moving towards sustainable health care systems), and by influencing the public debate.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 2","pages":"129-133"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Network care: what are we waiting for?]","authors":"K Hagoort, J J van Os, F E Scheepers","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>For years, enhanced collaboration within networks has been frequently suggested as a solution to the challenges in mental health care. Nevertheless, the practical implementation has been slow.</p><p><strong>Aim: </strong>To understand why the translation of network care from policy to practice is so challenging, and to identify entry points to overcome these obstacles.</p><p><strong>Method: </strong>We examine the intended transformation and its bottlenecks from the perspectives of care, innovation, change, and governance to gain insights into useful action perspectives.</p><p><strong>Results: </strong>From a care perspective, a shared understanding of what network care demands from all network members is helpful. Network care proves to be a complex innovation that requires courage from the board of directors and perseverance of all stakeholders. An incremental change approach within the existing organizational structure will facilitate the transition to network care. From a governance perspective, it is important to place the fundamental principles of quality care at the forefront and to reflect on previous mental healthcare reforms.</p><p><strong>Conclusion: </strong>To establish network care as the new standard practice, sustained efforts are required from both organizations and individual professionals within care networks.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 2","pages":"80-83"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The psychiatric trainees are the future of psychiatry in Europe].","authors":"L Gezels, M J Konings","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The European Federation of Psychiatric Trainees (EFPT) connects national trainees’ associations across Europe, fostering collaboration and knowledge exchange among psychiatric trainees. Currently, significant variations exist in training duration, examination requirements, and supervision methods, impacting both training quality and access to mental healthcare.</p><p><strong>Aim: </strong>To inform about the EFPT, as today’s psychiatric trainees represent Europe’s future psychiatrists. By exploring trainees’ experiences and training structures, a clearer view of psychiatry’s future can emerge.</p><p><strong>Method: </strong>To describe the EFPT organization (including member states, annual forum, working groups, and exchange programs), as well as the structure and content of psychiatric training across various European countries.</p><p><strong>Results: </strong>The EFPT organizes an annual forum that serves as a platform for knowledge exchange and policy development. Its working groups address specific themes within psychiatry, thereby offering valuable insight into training across different European countries.</p><p><strong>Conclusion: </strong>The EFPT plays an essential role in improving training quality through knowledge sharing and collaboration. Developing a standardized, competency-based curriculum that considers the diverse healthcare needs of member states is crucial for harmonizing training standards and improving mental healthcare across Europe.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 2","pages":"115-119"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnosis and treatment of conversion symptoms in the 1960s in Amsterdam].","authors":"M Vermeulen","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>According to Piet Kuiper, professor of psychiatry, conversion phenomena are more common in films and novels in Amsterdam in the 1960s than in outpatient clinics.</p><p><strong>Aim: </strong>To find out whether the neurologist Waterman has observed conversion phenomena in the 1960s; how he made this diagnosis, and what therapy did he use?</p><p><strong>Method: </strong>Research of Waterman’s patient files from the 1960s in Amsterdam.</p><p><strong>Results: </strong>In a group of 3372 patients, Waterman diagnosed hysterical or psychogenic neurological symptoms in 555 (16%) patients. Of these patients, 6.85% was eligible for psychoanalytic therapy. Waterman treated 54.95% of these patients with benzodiazepines and 25.77% with tricyclic antidepressants.</p><p><strong>Conclusion: </strong>In the 1960s, Waterman cannot refer 93% of his patients for psychoanalytic therapy, which according to Kuiper is necessary for the diagnosis and therapy of conversion disorder. This explains why the psychoanalyst Kuiper hardly sees patients with conversion symptoms. Waterman opts for symptomatic therapy for psychogenic neurological symptoms. He treats 4 out of 5 of his patients with pharmaceuticals. The beneficial effect he has observed may be a result of removing the concern about the symptoms by prescribing medication.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 3","pages":"164-168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G T M Mooren, L Reitsma, J Mouthaan, M J van Hoof, S P N Groen, L I M Lenferink
{"title":"[Symptoms of adjustment disorder during the COVID-19 pandemic: A longitudinal study].","authors":"G T M Mooren, L Reitsma, J Mouthaan, M J van Hoof, S P N Groen, L I M Lenferink","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This longitudinal study focuses on the question to what extent symptoms of adjustment disorder (AD) occurred in the Dutch population in response to the corona pandemic.</p><p><strong>Aim: </strong>To explore which (a) personal characteristics and which (b) pandemic, (c) health or (d) trauma-related factors are related to symptoms of AD.</p><p><strong>Method: </strong>2079 people (time 1) and 777 people (time 2) participated in an online questionnaire since 2020. Prevalence of adjustment disorder and the concurrent and longitudinal associations between the factors (a-d) and AD severity were determined.</p><p><strong>Results: </strong>A third experienced severe adjustment problems at the beginning of the pandemic and half a year later. However, there were changes in the course of adjustment: a large group of people did not meet the criteria for AD at time 1, while they did so at time 2, and vice versa. The observed factors (a-d) contributed to explaining the variation in adjustment disorder severity between participants (27% at time 1 and 44% at time 2, respectively), but did not do so completely.</p><p><strong>Conclusion: </strong>A more person-centered approach to study predictors of transitions in symptom patterns over time is needed. While a minority developed symptoms of AD, the majority has been able to cope well with the pandemic.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 3","pages":"159-163"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Recurrent fugues, also consider epilepsy].","authors":"J Broekmeulen, J Schulkens, C de Leeuw, E I Hoff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We discuss an interesting case of a 65-year-old man with multiple dissociative episodes which previously had been assessed as fugues. After evaluation in the memory clinic these episodes appeared to be generalized epileptic seizures, with an electro-encephalographic diagnosis of non-convulsive status epilepticus. Throughout this case, the different features that characterize an epileptic versus a psychiatric etiology are being discussed as well as other differential diagnostic considerations. A non-convulsive status epilepticus is a treatable disease which can being missed often. With this case, we intend to create awareness and clues to recognize this disease.</p>","PeriodicalId":23100,"journal":{"name":"Tijdschrift voor psychiatrie","volume":"67 1","pages":"50-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}