ACS Omega最新文献

{"title":"Coordination-Driven Directional Construction of Mn/Co@Carbon Aerogels and Thermal Catalysis of Ammonium Perchlorate","authors":"Neng Mei Deng,&nbsp;Ren Bo Meng,&nbsp;Yang Liu,&nbsp;Lu Lu Tang,&nbsp;Xu Cheng Fu* and Jun Zhao*,&nbsp;","doi":"10.1021/acsomega.5c0084610.1021/acsomega.5c00846","DOIUrl":"https://doi.org/10.1021/acsomega.5c00846https://doi.org/10.1021/acsomega.5c00846","url":null,"abstract":"<p >Previous studies have found that metal-doped carbon aerogels can effectively catalyze the thermal decomposition behavior of ammonium perchlorate (AP). In this study, a kind of carbon aerogel catalyst doped with Mn and Co was prepared by the bimetallic MOF (HMOF) precursor method through the key steps of gel and carbonization, and its thermal catalytic mechanism for AP was studied in detail. The results showed that Mn/Co@C aerogels had better catalytic performance than the monometal-doped carbon catalyst. When the addition amount was 2%, the heating rate was 10 °C/min, the decomposition peak temperature of AP was advanced by about 115 °C, and the thermal decomposition activation energy was reduced to 147 kJ·mol^–1.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21630–21636 21630–21636"},"PeriodicalIF":3.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c00846","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enzymatic Conversion of Mixed Neem (Azadirachta indica) and Nile Tilapia (Oreochromis niloticus) Oils into Biolubricants: A Green Biocatalytic Approach","authors":"Francisco Simão Neto,&nbsp;Patrick da Silva Sousa,&nbsp;Rafael Leandro Fernandes Melo,&nbsp;Antônio Luthierre Gama Cavalcante,&nbsp;Paulo Gonçalves de Sousa Junior,&nbsp;Sara Jessica Marciano,&nbsp;Diego Lomonaco,&nbsp;Raniere Dantas Valença,&nbsp;Frederico Ribeiro do Carmo,&nbsp;Marcos Carlos de Mattos,&nbsp;Maria Alexsandra de Sousa Rios,&nbsp;Paulo Roni de Souza,&nbsp;Aluísio Marques da Fonseca,&nbsp;Ada Sanders Lopes and José Cleiton Sousados Santos*,&nbsp;","doi":"10.1021/acsomega.4c1170710.1021/acsomega.4c11707","DOIUrl":"https://doi.org/10.1021/acsomega.4c11707https://doi.org/10.1021/acsomega.4c11707","url":null,"abstract":"<p >This study focused on optimizing the enzymatic synthesis of biolubricants using a 20% blend of Nile tilapia (<i>Oreochromis niloticus</i>) and neem (<i>Azadirachta indica</i>) oils catalyzed by Eversa Transform 2.0. The optimal conditions─the molar ratio of 1:5 (mol/mol), 10% biocatalyst load, and a reaction time of 48 h─achieved a predicted ester conversion of 97%, with experimental validation confirming 92.80 ± 0.03%. Molecular docking demonstrated stable complexes, particularly with decanoic and linoleic acids, showing Root Mean Square Deviation (RMSD) values below 2.0 Å, indicating minimal conformational changes. Gas chromatography and mass spectrometry (GC-MS) analysis identified key esters like 2-ethylhexyl and octyl, which enhance thermal stability, lubricity, and oxidation resistance. Fourier Transform Infrared Spectroscopy (FT-IR) analysis confirmed effective ester formation, corroborating experimental results. Viscosity (2.4511 mm²/s) and density (0.84259 g/cm³) values aligned with ISO VG 3 (International Organization for Standardization Viscosity Grade) standards, suitable for low-load and low-speed applications.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21361–21376 21361–21376"},"PeriodicalIF":3.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.4c11707","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Different Gaseous Plasmas and Plasma Treatment Durations on Coal Structure","authors":"Fan Yang,&nbsp;Qingguo Xue,&nbsp;Haibin Zuo and Jingsong Wang*,&nbsp;","doi":"10.1021/acsomega.5c0255610.1021/acsomega.5c02556","DOIUrl":"https://doi.org/10.1021/acsomega.5c02556https://doi.org/10.1021/acsomega.5c02556","url":null,"abstract":"<p >Coal samples were treated with air, N₂, and O₂ plasmas for varying times to study plasma type and duration effects on coal structural characteristics. FTIR, Raman, and XRD analyses systematically evaluated the chemical structural changes. Results showed plasma type and treatment time significantly impacted coal’s aromatic structures, aliphatic configurations, oxygen-containing groups, graphitization degree, aliphatic chain length, and aromatic stacking layers. FTIR parameters (<i>f</i>_a, <i>I</i>, DOC, <i>O</i>_c) indicated short-term air, N₂, and O₂ plasma treatments reduced aromaticity while increasing aliphatic groups and oxygen-containing moieties. Short-term plasma reduced crystallographic ordering with air plasma, causing the most pronounced structural changes. XRD revealed plasma-modified aromatic lamella densification via <i>d</i>₀₀₂ spacing variations. Stacking height (<i>L</i>_c) and lateral dimension (<i>L</i>_a) contracted initially and then expanded with longer treatment for all plasma types. Aliphatic chain development (evidenced by an increased <i>L</i>_γ) influenced coal reactivity. Rising <i>N</i> and <i>P</i> values showed an increased graphitization with treatment time. The plasma-induced mechanistic changes in coal macromolecules were elucidated based on these structural alterations. This study first reveals dual-threshold effects of time-dependent plasma treatment on coal graphitization and reactivity.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"22191–22203 22191–22203"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c02556","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Copyrolysis of Municipal Sewage Sludge with Agricultural Residues: A Theoretical and Experimental Study for Tailored Biochar Production","authors":"Naeimeh Vali*,&nbsp;Samyar Zabihi,&nbsp;Abas Mohsenzadeh and Anita Pettersson,&nbsp;","doi":"10.1021/acsomega.4c1108910.1021/acsomega.4c11089","DOIUrl":"https://doi.org/10.1021/acsomega.4c11089https://doi.org/10.1021/acsomega.4c11089","url":null,"abstract":"<p >Municipal sewage sludge (MSS) has been identified as a promising feedstock for producing biochar with potential applications as a soil conditioner and animal feed. However, the high heavy metal content and limited availability of nutrients, such as phosphorus (P), pose significant challenges. This study aimed to improve the quality of MSS-derived biochar through copyrolysis with wheat straw (rich in K and Si) and bakery waste husks (rich in K) at temperatures of 500, 650, and 900 °C. Thermodynamic equilibrium calculations (TEC) were performed using FactSage and HSC Chemistry to predict the stability of P-bearing compounds and the fate of heavy metals in the biochars. The morphology and physicochemical properties of the biochars were examined by using SEM and Brunauer–Emmett–Teller (BET) analyses. The results indicate that increasing the proportions of wheat straw and bakery waste husks, along with higher pyrolysis temperatures, reduced the biochar yield. TEC demonstrated that these blends enhanced the formation of plant-available phosphates compared with pure MSS biochar. This improvement was primarily because of the formation of K/Mg-bearing phosphates in different amorphous and crystalline phases, such as K₂P₂O₇, CaK₂P₂O₇, KPMgO₄, and KZnPO₄, instead of Fe/Al-based phosphates. Additionally, copyrolysis reduced the concentrations of heavy metals such as cadmium (Cd), lead (Pb), and zinc (Zn) in the biochars compared to MSS pyrolysis alone. However, it had no significant effect on the copper (Cu), chromium (Cr), and nickel (Ni) levels. In conclusion, copyrolysis with wheat straw and bakery waste husks not only improved the nutrient profile and physicochemical properties of MSS-derived biochar but also mitigated heavy metal contamination. Additionally, this method reduced the presence of heavy metals, making it a more suitable alternative to biochar produced through monopyrolysis for use in agricultural applications.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21308–21323 21308–21323"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.4c11089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Preparation and Properties of Volatile Tris(N-Alkoxycarboxamidato)chromium(III) Complexes as Potential Single-Source Precursors for the MOCVD of Crystalline Chromium Oxide Thin Films","authors":"Ji Hun Kim,&nbsp;Da Som Song,&nbsp;Sunyoung Shin,&nbsp;Ji Yeon Ryu,&nbsp;Duk-Young Jung,&nbsp;Jongsun Lim* and Chang Gyoun Kim*,&nbsp;","doi":"10.1021/acsomega.5c0038010.1021/acsomega.5c00380","DOIUrl":"https://doi.org/10.1021/acsomega.5c00380https://doi.org/10.1021/acsomega.5c00380","url":null,"abstract":"<p >The synthesis, characterization, and vapor-phase growth of volatile Cr(III) complexes as single-source precursors for Cr₂O₃ thin films are reported. A series of Cr complexes─Cr(mdpa)₃ (mdpa = <i>N</i>-methoxy-2,2-dimethylpropanamide) (<b>1</b>), Cr(edpa)₃ (edpa = <i>N</i>-ethoxy-2,2-dimethylpropanamide) (<b>2</b>), Cr(empa)₃ (empa = <i>N</i>-ethoxy-2-methylpropanamide) (<b>3</b>), and Cr(mpa)₃ (mpa = <i>N</i>-methoxypropanamide) (<b>4</b>)─were synthesized via salt elimination reactions between CrCl₃·3THF and <i>N</i>-alkoxy carboxamidate salts. These complexes were characterized by Fourier transform infrared spectroscopy, elemental analysis, thermogravimetric analysis (TGA), single-crystal X-ray diffraction (SC-XRD), Hirshfeld surface analysis, powder X-ray diffraction (PXRD), and vapor pressure measurement. The crystal structure of complex <b>1</b> revealed a distorted octahedral geometry with a κ² (O,O) binding mode. TGA demonstrated that complex <b>1</b> underwent weight loss at 132 °C and no residue remained at 500 °C. The enthalpy of vaporization of <b>1</b> was estimated to be 25.58 kJ/mol, making it an optimal precursor for Cr₂O₃ thin films. The XRD patterns of Cr₂O₃ films deposited on SiO₂/Si substrates confirmed their crystalline nature, showing prominent peaks at 2θ = 33.5° and 41.5°. In addition, X-ray photoelectron spectroscopy validated the target Cr/O ratio, supporting the successful formation of Cr₂O₃ films.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21519–21528 21519–21528"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c00380","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesis of Biogenic Nano Zerovalent Iron Using Cleistocalyx nervosum Leaf Extract for Enhancing Peanut Seed Germination and Basella alba Growth","authors":"Phuong Thi Hong Nguyen,&nbsp;Hoai Phuong Nguyen Thi,&nbsp;Huu Thuan Mai,&nbsp;Casen Panaitescu,&nbsp;Duong Duc La and Duy Khiem Nguyen*,&nbsp;","doi":"10.1021/acsomega.5c0242110.1021/acsomega.5c02421","DOIUrl":"https://doi.org/10.1021/acsomega.5c02421https://doi.org/10.1021/acsomega.5c02421","url":null,"abstract":"<p >In this study, biogenic nano zerovalent iron (bio-nZVI) was synthesized through a green approach using <i>Cleistocalyx nervosum</i> (<i>C. nervosum</i>) leaf extract for use as a nanopriming agent for improving peanut seed germination and <i>Basella alba</i> growth. The scanning electron microscopy (SEM), Fourier-transform infrared (FT-IR), and X-ray diffraction (XRD) results demonstrated that bio-nZVI was successfully synthesized. The as-synthesized bio-nZVI had a spherical shape with a size ranging from 80 to 350 nm. The prepared bio-nZVI had a core–shell structure with a core of Fe⁰ and a shell of Fe₂O₃, and this core–shell structure was covered by an organic layer derived from the leaf extract. The synthesized bio-nZVI was applied to peanut seeds and <i>Basella alba</i> plants at concentrations ranging from 10 to 320 mg/L to enhance seed germination and plant growth. The results demonstrated that bio-nZVI at optimal concentrations of 20–40 mg/L could significantly improve peanut seed germination and promote <i>Basella alba</i> growth. However, no significant effect on enhancing peanut seed germination and <i>Basella alba</i> plant growth was observed when applying a bio-nZVI solution at higher concentrations. These findings suggest that bio-nZVI could be a promising germination promoter and eco-friendly growth enhancer for agricultural applications; thereby, it has great potential for increasing crop productivity and meeting demand for grain worldwide.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"22137–22145 22137–22145"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c02421","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"β-Selective Addition of Pyrroles to Electron-Deficient Alkenes in Both Catalytic and Stoichiometric Modes on B(C6F5)3","authors":"Seina Sekine,&nbsp;Miho Kashiwa,&nbsp;Maho Kawakami,&nbsp;Takumi Sonoda,&nbsp;Arisa Ono and Teruhisa Tsuchimoto*,&nbsp;","doi":"10.1021/acsomega.5c0037110.1021/acsomega.5c00371","DOIUrl":"https://doi.org/10.1021/acsomega.5c00371https://doi.org/10.1021/acsomega.5c00371","url":null,"abstract":"<p >To the best of our knowledge, the addition of pyrroles to electron-deficient alkenes (APEda) via electrophilic aromatic substitution (S_EAr) has been reported to occur exclusively at the α-position of the pyrrole without any formation, even in trace amounts, of a β-adduct, β-<b>3</b>. In sharp contrast to the prolonged immutable observation, we established an original S_EAr-based APEda (S_EAr-APEda) system applicable to both the catalytic and stoichiometric synthesis of β-<b>3</b>.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21510–21518 21510–21518"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c00371","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature-Driven Morphological and Microstructural Changes of Gold Nanoparticles Prepared by Aggregation from the Gas Phase","authors":"Tereza Košutová*,&nbsp;Zdeněk Krtouš*,&nbsp;Jaroslav Kousal,&nbsp;Ondřej Kylián,&nbsp;Jan Hanuš,&nbsp;Lidia Martínez,&nbsp;Yves Huttel,&nbsp;Daniil Nikitin,&nbsp;Pavel Pleskunov,&nbsp;Hynek Biederman,&nbsp;Lukáš Horák and Milan Dopita,&nbsp;","doi":"10.1021/acsomega.5c0214910.1021/acsomega.5c02149","DOIUrl":"https://doi.org/10.1021/acsomega.5c02149https://doi.org/10.1021/acsomega.5c02149","url":null,"abstract":"<p >The effect of annealing on the thin layers of gold and gold nanoparticles in air was studied by statistically relevant X-ray scattering methods. The nanoparticle behavior is found to depend on the substrate coverage and annealing temperature. During annealing up to 450 °C, the size of single-crystalline nanoparticles gradually increases through the process of Ostwald ripening, while the density of crystallographic defects decreases slightly. An abrupt change occurs above 450 °C, whereas no significant evolution is observed for the less covered sample; at the sample with more material, the nanoparticles coalesce, and their shape becomes more rounded by further annealing. Only after the spheroidization is completed do the sizes of crystallites follow the nanoparticle size growth. Comparison with the thin continuous gold layer shows that the healing of the crystallographic defects, i.e., microstrain and stacking faults, takes place at significantly lower temperatures if the material is evenly distributed on the silicon substrate surface. However, annealed nanoparticle layers provide a much narrower particle size distribution when compared to a dewetted gold thin layer. At around 800 °C, the alignment of the gold crystal structure toward the substrate is detected, and it changes from the random distribution of the atomic planes given by the random initial orientation of deposited nanoparticles. Another interesting phenomenon occurs for annealing above 1000 °C; for the nanoparticle layers, the smallest nanoparticles evaporate, leaving holes in the SiO₂ surface layer.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"22052–22061 22052–22061"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c02149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Water-Repellent and UV-Resistant Properties of Polyester Fabric with Water-Based Carbon Black by Coating","authors":"Xin Wang,&nbsp;Yilin Wu,&nbsp;Hongmei Cao,&nbsp;Keshuai Liu* and Li Ai*,&nbsp;","doi":"10.1021/acsomega.4c0822810.1021/acsomega.4c08228","DOIUrl":"https://doi.org/10.1021/acsomega.4c08228https://doi.org/10.1021/acsomega.4c08228","url":null,"abstract":"<p >Carbon black, as a pigment, has the characteristics of antiultraviolet and antistatic properties and has a wide range of applications in rubber, smart wear, and textiles. In this study, water-based carbon black with good dispersion properties was prepared by mechanical high-speed shear and applied to a polyester fabric. The particle size, placement stability, and rheology of water-based carbon black were investigated. The carbon black is successfully loaded onto the polyester fabric (PET) by scraping and coating. The effect of carbon black concentration on the antiultraviolet and water-repellent properties of polyester fabric was discussed. The results show that the average particle size of liquid carbon black is 240 nm, PDI = 0.375, the particle size of self-made liquid carbon black in the laboratory is normally distributed, stored for 90 days, and the particle size increases slightly. The relationship between shear stress and shear rate of liquid carbon black can be described by the power exponential equation, and the relationship between viscosity and shear rate can be described by the Morgan Mercer Florin formula. When the amount of CB is 10%, the UV radiation protection factor (UPF) of the PET fabric is 164.66, and the UV resistance of the fabric is more than 2 times higher than that of the original fabric. The water contact angle of the PET/CB fabric is 126.6°. After 300 times of friction and 10 times of washing, the UPF remained 146.01 and 126.61, and the contact angle decreased to 106° and 111.4°, respectively. The air permeability and moisture permeability are improved by 30 and 16%, respectively. When the amount of carbon black is less than 10%, the dry and wet friction fastness of the fabric is higher than 3/4, which provides a new preparation method for functional finishing and dyeing of the polyester fabric.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21077–21085 21077–21085"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.4c08228","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Cyclopeptide and γ-Butyrolactone Derivatives from an Endophytic Strain of Cophinforma mamane","authors":"Clara Litot,&nbsp;Marieke Vansteelandt*,&nbsp;Sergio Ortiz,&nbsp;Fatima Barakat,&nbsp;Elise Crossay,&nbsp;Doriane Titton,&nbsp;Sandra Bourgeade-Delmas,&nbsp;Carlos Amasifuen,&nbsp;Jérôme Graton,&nbsp;Denis Jacquemin,&nbsp;Jean-Luc Stigliani,&nbsp;Mohamed Haddad and Nicolas Fabre*,&nbsp;","doi":"10.1021/acsomega.5c0129210.1021/acsomega.5c01292","DOIUrl":"https://doi.org/10.1021/acsomega.5c01292https://doi.org/10.1021/acsomega.5c01292","url":null,"abstract":"<p >From an endophytic strain of <i>Cophinforma mamane</i> isolated from the leaves of <i>Bixa orellana</i>, a previously undescribed γ-butyrolactone compound (<b>2</b>) and three new cyclopentapeptides (<b>3</b>-<b>5</b>) have been isolated from the same strain, along with the known (4<i>R)</i>-striatisporolide A (<b>1</b>). Their structures were elucidated through extensive spectral analysis and DP4+ calculations. The two γ-butyrolactone derivatives (<b>1</b>, <b>2</b>) exhibited moderate inhibitory activity against axenic <i>Leishmania infantum</i> amastigotes (IC₅₀ = 13.33 and 4.43 μM, respectively), while only compound <b>2</b> displayed cytotoxic activity on Jurkat cells (17% growth inhibition at 1 μg/mL) and weak antibacterial activity against <i>Enterococcus faecalis</i> (MIC = 64 μg/mL).</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 21","pages":"21738–21746 21738–21746"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c01292","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}