ACS Omega最新文献

{"title":"Turning Waste into Resource: Red Mud as a Sustainable Alternative to Class G Cement in Surface Casing Cementing","authors":"Ahmed Abdulhamid Mahmoud*,&nbsp;","doi":"10.1021/acsomega.4c1160110.1021/acsomega.4c11601","DOIUrl":"https://doi.org/10.1021/acsomega.4c11601https://doi.org/10.1021/acsomega.4c11601","url":null,"abstract":"<p >Sustainability of well cementing operations is a growing concern due to the high carbon footprint of Class G cement production. This study investigates the feasibility of using red mud, an industrial by-product of alumina manufacturing, as a partial replacement for Class G cement in surface casing cementing. A series of laboratory experiments was conducted to evaluate the mechanical, rheological, and performance characteristics of red mud-based cement slurries. The tests included compressive strength, plastic viscosity, yield point, gel strength, 3-rpm reading, free water content, fluid loss, and thickening time. A comparison of red mud–cement blends to a conventional Class G cement slurry was also considered in this study. The results demonstrated that the incorporation of red mud in a concentration of more than 15% resulted in crack development on the outer surface of the samples with time, and also the sample with 50% red mud showed a very high plastic viscosity, which makes it unpumpable. Red mud incorporation significantly reduced the free water content while maintaining an acceptable compressive strength above the required 700 psi threshold. However, its addition lowered the yield point and gel strength, necessitating viscosifier inclusion to restore suspension capacity. The slurry with 15% red mud showed optimal performance when combined with 0.12% viscosifier, balancing pumpability, stability, and thickening time requirements. The findings highlight that red mud-based cement formulations can provide a sustainable alternative to Class G cement, reducing waste disposal challenges and environmental impact.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20286–20298 20286–20298"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.4c11601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Intermittent Fasting on Survival and Gene Expression Profiles Associated with Autophagy, Metabolism, and Antioxidant in <i>Drosophila melanogaster</i>.","authors":"Fifi Dismayanti Indriani Nainu, Aryadi Arsyad, Aminuddin Aminuddin, Andi Ariyandy, Asbah Asbah, Nadila Pratiwi Latada, Nur Rahma Rumata, Firzan Nainu","doi":"10.1021/acsomega.5c00400","DOIUrl":"10.1021/acsomega.5c00400","url":null,"abstract":"<p><p>Intermittent fasting (IF) has attracted significant interest as a potential approach with promising health benefits, including lifespan extension and metabolic improvement. Previous studies have shown that IF influences autophagy, metabolism, and oxidative stress across various organisms. <i>Drosophila melanogaster</i> was used in this study due to its genetic structure and metabolic responses that closely resemble those of humans, making it a valuable model for studying the effects of IF on cellular and molecular mechanisms. This study investigates the effects of IF on survival and the expression of genes related to autophagy, metabolic, and endogenous antioxidants in <i>D. melanogaster</i> to elucidate the molecular mechanisms underlying these effects. Male <i>w</i> ^<i>1118</i> flies were subjected to either a 4-h or 8-h fasting protocol, three times per week. The results revealed that both fasting protocols improved the survival of flies, with the 8-h IF group showing the most significant benefit (over 60% survival at day 10 compared to ∼50% in the control). Gene expression analysis demonstrated a significant downregulation in the fasting groups, with <i>dilp2</i> decreasing by 45%, <i>tom40</i> by 40%, <i>cat</i> by 50%, <i>srl</i> by 35%, and <i>atg8a</i> by 48%, indicating reduced insulin signaling, altered mitochondrial function, decreased antioxidant defense, and suppressed autophagy-related pathways. Notably, these findings contrast with previous studies reporting upregulation of autophagy and antioxidant responses during fasting, suggesting context-dependent regulatory mechanisms. Given the genetic and physiological similarities between <i>D. melanogaster</i> and mammals, these results provide insights into IF-induced metabolic adaptations and their potential implications for longevity and cellular homeostasis. Further research is warranted to clarify the molecular pathways involved.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 19","pages":"19636-19642"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking the Dynamics of Ion Migration and Voltage Bias Stress Effects through Crystallite Engineering in Metal Halide Perovskites","authors":"Laura Flannery,&nbsp;Kelsey Garden,&nbsp;Alex Berzansky,&nbsp;Xueqiao Zhang,&nbsp;John G. Labram and Luisa Whittaker-Brooks*,&nbsp;","doi":"10.1021/acsomega.5c0118210.1021/acsomega.5c01182","DOIUrl":"https://doi.org/10.1021/acsomega.5c01182https://doi.org/10.1021/acsomega.5c01182","url":null,"abstract":"<p >Understanding the interplay between crystal engineering and the coupled electronic-ionic charge transport properties of metal halide perovskites remains a critical issue in the field. In this work, we developed an experimental approach to tune the crystallite orientation of methylammonium lead iodide (CH₃NH₃PbI₃) while maintaining their overall crystal structure. This approach allows us to selectively manipulate crystallite orientations to control out-of-plane ion migration and mitigate voltage bias stress effects in CH₃NH₃PbI₃ thin films. By employing advanced diffraction and spectroscopic techniques, we achieved a comprehensive characterization of the anisotropic crystallite properties in CH₃NH₃PbI₃ thin films with distinct preferred orientations. Our findings reveal that specific crystallite orientations, particularly those that limit halide ion migration pathways along the (200) crystallographic plane, significantly suppress out-of-plane ion migration. This suppression reduces hysteresis and alleviates voltage bias stress effects in CH₃NH₃PbI₃ solar cells, ultimately enhancing device stability and performance. These insights not only deepen our understanding of the relationship between crystallite orientation and device functionality but also highlight a promising strategy for regulating ion migration in MHP-based devices. This approach holds significant potential for advancing the stability and efficiency of perovskite solar cells and extending its applicability to other optoelectronic devices.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20536–20549 20536–20549"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c01182","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theoretical Prediction of a Novel Phase Ti2B2 Monolayer as an Outstanding Electrode Material for Lithium/Sodium-Ion Batteries","authors":"Zheng Dai,&nbsp;Xixi Jia and Lina Bai*,&nbsp;","doi":"10.1021/acsomega.5c0069910.1021/acsomega.5c00699","DOIUrl":"https://doi.org/10.1021/acsomega.5c00699https://doi.org/10.1021/acsomega.5c00699","url":null,"abstract":"<p >Transition metal borides (MBenes) have provoked widespread interest in the field of power storage due to their excellent electrochemical performance. Using structural prediction software and first-principles calculations, a two-dimensional Ti₂B₂ phase has been predicted; it possesses favorable structural stability and metal-like electronic characteristics. The Ti₂B₂ monolayer is suitable as an electrode material for lithium/sodium storage due to its excellent ion migration ability, moderate open circuit voltage, and high storage capacity. Especially, the theoretical capacity broke the upper limit of the Li (double-layer) and Na (single-layer) storage of MBenes with transition metals as surfaces, and the diffusion barrier of the Li atom is 1 order of magnitude lower than those of other MBenes. Besides, the adsorbed ions maintain a complete and orderly layered arrangement at 500 K, which ensures excellent cycling performance. This work provides a novel orientation for designing electrode materials of secondary batteries in fields such as portable electronics and electric vehicles.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20465–20473 20465–20473"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c00699","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytotoxicity and Nanoassembly Characteristics of Aromatic Amides of Oleanolic Acid and Ursolic Acid","authors":"Uladzimir Bildziukevich,&nbsp;Marie Kvasnicová,&nbsp;David Šaman,&nbsp;Lucie Rárová*,&nbsp;Miroslav Šlouf* and Zdeněk Wimmer*,&nbsp;","doi":"10.1021/acsomega.5c0276010.1021/acsomega.5c02760","DOIUrl":"https://doi.org/10.1021/acsomega.5c02760https://doi.org/10.1021/acsomega.5c02760","url":null,"abstract":"<p >A series of more than 20 new amides of oleanolic acid and ursolic acid with selected aromatic amines were synthesized, and the structures of all compounds were analyzed and elucidated. Moreover, the compounds were subjected to the cytotoxicity assays in four cancer cell lines (CCRF-CEM, MCF7, HeLa, and G-361), using normal human fibroblasts (BJ) as reference cells for determining the toxicity of the investigated compounds. The 1,10-phenanthroline derivatives <b>4a</b>, <b>4b</b>, <b>5a</b>, and <b>5b</b> showed the highest cytotoxicity in all four cancer cell lines, but they were comparably toxic in human fibroblasts. The most promising results were achieved with <b>14a</b> and <b>14b</b> showing high cytotoxicity in the cancer cell lines and no toxicity in human fibroblasts. They were subjected to the investigation of the in vitro cell apoptosis, resulting in a confirmation of activation of apoptotic pathways in the CCRF-CEM cell line. The structure–activity relationships were documented by the cytotoxicity of <b>14a</b> vs. <b>16a</b>, and of <b>14b</b> vs <b>16b</b>, showing reverse effects in CCRF-CEM and MCF7 cancer cell lines. To investigate nanoassembly, initial screening of the target compounds by ultraviolet (UV) spectrometry was performed. Compounds <b>9b</b>, <b>13b</b>, <b>16b</b>, and <b>17b</b>, soluble both in methanol and in water, were selected for a more detailed investigation by transmission electron microscopy (TEM) microscopy and were found to form spherical nanoassemblies, frequently interconnected in small agglomerates and/or loose networks, while the other target compounds of this series showed no nanoassembling based on the TEM imaging. For each investigated compound, the nanoassemblies formed in methanol were substantially bigger than those formed in water.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20938–20948 20938–20948"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c02760","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forecasting the Potential for Clean Mineral Recycling in the Electrification Transition of Public Buses in Extra-Large Cities: A Case Study of Beijing","authors":"Xinping Li,&nbsp;Huajiao Li*,&nbsp;Di Dong,&nbsp;Ziyao An and Ya Wang,&nbsp;","doi":"10.1021/acsomega.5c0179310.1021/acsomega.5c01793","DOIUrl":"https://doi.org/10.1021/acsomega.5c01793https://doi.org/10.1021/acsomega.5c01793","url":null,"abstract":"<p >In the context of the low-carbon development of the transport industry, with the trend of low-carbon development of new energy vehicles and rapid growth in the number of demonstrations and promotions, urban public transport has also formally entered the transition period of electrification, and the rapid development of electrification of public transport is becoming an important part of the realization of low-carbon transport systems. To provide a detailed description of the clean minerals stock and its structure in the public transportation system of a megacity, this paper uses Beijing’s urban public transport as a case study. By integrating material flow analysis methods and diverse heterogeneous data sets, this study investigates the stock of eight clean minerals─lithium (Li), cobalt (Co), nickel (Ni), manganese (Mn), aluminum (Al), platinum (Pt), palladium (Pd), and rhodium (Rh)─in the city’s bus system. Additionally, the accumulation patterns and recycling potential of these clean minerals under scenarios of the accelerated electrification of urban buses and the development of lithium battery cathode technologies are discussed. The study finds that the total stock of the eight clean minerals in Beijing’s urban buses exceeds 10,000 tons from 2011 to 2022, with a nearly 7-fold increase in the annual stock of the metals, of which nickel and manganese account for approximately 30% of the total stock of the metals. Under the scenario of accelerated electrification of urban buses, the total metal stock reaches 28,000 tons in 2023–2050, and the lithium metal increases by 65% compared with that in the baseline scenario. Under the scenario of development of lithium battery cathode technology, the total metal stock decreases by nearly 20% compared with that in the baseline scenario, which shows that the development of lithium battery cathode technology plays an important role in saving clean mineral resources. Under the dual acceleration scenario of urban public transport and lithium batteries, the metal stock decreases to 22,000 tons, with lithium stock accounting for 3/4 of the total stock, showing that the development of electrification and lithium battery technology may lead to significant challenges in terms of the lithium supply. This study estimates the stock of clean mineral materials for urban public transport in Beijing, and the case study of Beijing is useful not only for comparison with similar cities in industrialized countries but also as a reference for the sustainability transition of other types of cities.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20732–20743 20732–20743"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c01793","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Allosteric Inhibitor Pentachloropseudilin Inhibits Myosin 1C ATPase Activity and Recapitulates Retinitis Pigmentosa Phenotypes in Mice","authors":"Rakesh Radhakrishnan,&nbsp;René Martin,&nbsp;Rafael da Costa Monsanto,&nbsp;Anjelynt Lor,&nbsp;Andrew Gruesen,&nbsp;Matthias Leung,&nbsp;Heidi Roehrich,&nbsp;Nevra Keskin-Yilmaz,&nbsp;Sebahattin Cureoglu,&nbsp;Vladimir Tsuprun,&nbsp;Frederik J. van Kuijk,&nbsp;Bärbel Rohrer,&nbsp;Hans-Joachim Knölker* and Glenn P. Lobo*,&nbsp;","doi":"10.1021/acsomega.5c0216210.1021/acsomega.5c02162","DOIUrl":"https://doi.org/10.1021/acsomega.5c02162https://doi.org/10.1021/acsomega.5c02162","url":null,"abstract":"<p >Unconventional myosins are molecular motors that move along actin filaments in an ATPase-dependent manner, thereby influencing intracellular cargo transport. Dysfunction of myosins due to loss-of-function mutations causes human disease phenotypes such as deafness, retinitis pigmentosa, renal failure, and hypertrophic cardiomyopathy. However, some genetic models lacking unconventional myosins do not recapitulate the retinal phenotypes observed in humans, necessitating alternative approaches. We previously showed that the myosin motor protein MYO1C is required for the trafficking of rhodopsin in mouse photoreceptors and for visual function. To investigate whether MYO1C could be nongenetically inhibited, we used the natural compound pentachloropseudilin (PCIP) to allosterically inhibit MYO1C-ATPase motor activity. PCIP treatment of COS1 cells coexpressing GFP-rhodopsin and mCherry-MYO1C resulted in an aggregation of GFP-rhodopsin protein in the cytoplasm and impaired the kinetics of rhodopsin foci movement. Conversely, GFP-rhodopsin trafficked efficiently to the plasma membrane in non-PCIP-treated COS1 cells. PCIP effects in vivo were then analyzed in wild-type mouse retinas based on evaluations of opsin trafficking, visual response measurements using ERGs, and quantification of rhodopsin recovery rates after photobleaching. Intravitreous injections of PCIP into WT mice caused significant rhodopsin mislocalization and shorter rod photoreceptor outer segments, resulting in reduced scotopic visual responses, thereby recapitulating retinitis pigmentosa phenotypes commonly observed in humans. Our study provides evidence from live-cell analysis and vertebrate retinas that using PCIP can recapitulate the retinal phenotypes observed in humans with myosin mutations. Furthermore, it confirms in a nongenetic model the requirement for MYO1C in photoreceptor opsin trafficking, maintenance of photoreceptor outer segments, and visual function.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20817–20829 20817–20829"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c02162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal Wavelengths and Solvents to Modulate Diazirine Kinetics","authors":"Elwin W. J. Ang,&nbsp;Ivan Djordjevic,&nbsp;Animesh Ghosh,&nbsp;Chen Yee Goh,&nbsp;Hao Zhang,&nbsp;Bryce Yu Heng Leck,&nbsp;Miranda J. Baran,&nbsp;Jeremy E. Wulff and Terry W. J. Steele*,&nbsp;","doi":"10.1021/acsomega.4c1033710.1021/acsomega.4c10337","DOIUrl":"https://doi.org/10.1021/acsomega.4c10337https://doi.org/10.1021/acsomega.4c10337","url":null,"abstract":"<p >Diazirine photolysis generates reactive carbene species, useful for indiscriminate cross-linking and insertion reactions with amino acids and polyolefins. However, methods to increase the carbene efficiency and limit the benign diazoalkane intermediate remain uncharted. Herein, we correlate diazirine depletion to common experimental parameters such as LED wavelength, temperature, solvent, and grafted functional groups. Broad wavelength activation impeded the formation of diazoalkane, presenting a light-based method to limit this yellow-inducing intermediate. Kinetics rate (per joule) values of diazirine depletion and diazoalkane generation served as the performance metric, permitting comparisons across all parameter variables. Photokinetics were independent of temperature from 25 to 70 °C. Highest rates were found in ester-containing solvents and ether conjugated diazirine. Overall, the novel irradiation arrangement reduces the reliance on UVA for photoactivation and increases the efficiency of diazirine as a carbene precursor.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20150–20159 20150–20159"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.4c10337","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Intermittent Fasting on Survival and Gene Expression Profiles Associated with Autophagy, Metabolism, and Antioxidant in Drosophila melanogaster","authors":"Fifi Dismayanti Indriani Nainu,&nbsp;Aryadi Arsyad,&nbsp;Aminuddin Aminuddin,&nbsp;Andi Ariyandy,&nbsp;Asbah Asbah,&nbsp;Nadila Pratiwi Latada,&nbsp;Nur Rahma Rumata and Firzan Nainu*,&nbsp;","doi":"10.1021/acsomega.5c0040010.1021/acsomega.5c00400","DOIUrl":"https://doi.org/10.1021/acsomega.5c00400https://doi.org/10.1021/acsomega.5c00400","url":null,"abstract":"<p >Intermittent fasting (IF) has attracted significant interest as a potential approach with promising health benefits, including lifespan extension and metabolic improvement. Previous studies have shown that IF influences autophagy, metabolism, and oxidative stress across various organisms. <i>Drosophila melanogaster</i> was used in this study due to its genetic structure and metabolic responses that closely resemble those of humans, making it a valuable model for studying the effects of IF on cellular and molecular mechanisms. This study investigates the effects of IF on survival and the expression of genes related to autophagy, metabolic, and endogenous antioxidants in <i>D. melanogaster</i> to elucidate the molecular mechanisms underlying these effects. Male <i>w</i>^<i>1118</i> flies were subjected to either a 4-h or 8-h fasting protocol, three times per week. The results revealed that both fasting protocols improved the survival of flies, with the 8-h IF group showing the most significant benefit (over 60% survival at day 10 compared to ∼50% in the control). Gene expression analysis demonstrated a significant downregulation in the fasting groups, with <i>dilp2</i> decreasing by 45%, <i>tom40</i> by 40%, <i>cat</i> by 50%, <i>srl</i> by 35%, and <i>atg8a</i> by 48%, indicating reduced insulin signaling, altered mitochondrial function, decreased antioxidant defense, and suppressed autophagy-related pathways. Notably, these findings contrast with previous studies reporting upregulation of autophagy and antioxidant responses during fasting, suggesting context-dependent regulatory mechanisms. Given the genetic and physiological similarities between <i>D. melanogaster</i> and mammals, these results provide insights into IF-induced metabolic adaptations and their potential implications for longevity and cellular homeostasis. Further research is warranted to clarify the molecular pathways involved.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 19","pages":"19636–19642 19636–19642"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c00400","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Review: Research and Application of Microwave Heating Technology in In Situ Exploitation of Oil Shale","authors":"Xiaoliang Zhao*,&nbsp;","doi":"10.1021/acsomega.5c0194610.1021/acsomega.5c01946","DOIUrl":"https://doi.org/10.1021/acsomega.5c01946https://doi.org/10.1021/acsomega.5c01946","url":null,"abstract":"<p >Oil shale is a rich unconventional energy source that has not been valued in the past due to its high mining costs and low economic benefits. However, with the gradual depletion of conventional crude oil resources, the economic value of oil shale has become increasingly significant. Microwave heating technology, with its efficient energy conversion and good penetration, has become a strong candidate for in situ oil shale mining. For example, studies have shown that microwave heating can achieve a heating efficiency of up to 80% in certain oil shale samples, which is significantly higher than that of traditional methods such as conduction heating (around 50%) and convection heating (around 60%). However, comprehensive reviews on the application of microwave heating technology in oil shale in situ mining are still rare. This review systematically reviews the application progress of microwave heating technology in in situ oil shale mining, including microwave heating devices, dielectric properties of oil shale, numerical simulation techniques, and methods for improving heating efficiency. The research found that optimizing microwave frequency, improving magnetron design, and adding microwave absorbers can significantly improve the heating efficiency and uniformity. In addition, the technology is also environmentally friendly and can achieve crude oil cracking and desulfurization under the action of a catalyst, improving the quality of the crude oil.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 20","pages":"20059–20077 20059–20077"},"PeriodicalIF":3.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.5c01946","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}