Journal of Bio Innovation最新文献

{"title":"EVALUATION OF THE PERFORMANCE OF THE CONSTRUCTION OF THE INFRASTRUCTURE OF THE ABC ROAD THROUGH PUBLIC FUNDS","authors":"","doi":"10.46344/jbino.2024.v13i03.09","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.09","url":null,"abstract":"Purpose:The objective of this research is to assess the viability of the construction of toll road infrastructure through public funds in the case of the construction of ABC street toll road, as well as to analyze the development of ABC road toll road, whether it is favorable or unfavorable to the community. Design/Methodology/Approach:The research was conducted using a mixed approach of qualitative and quantitative methods with concurrent or simultaneous designs. In this method, researchers combine quantitative and qualitative data at a time and then integrate information into the interpretation of results to provide a comprehensive analysis of research at the PT. ABC. Findings: The results of this study show that the calculation of the NPV of the construction of ABC street toll roads yields a value > 0, thus the development of this toll road infrastructure is worthy of a net present value (NPV). The Internal Rate of Return (IRR) of the construction of ABC street toll roads is 10% > the Social Discount Rate (SDR), thus building the ABC road toll is worthy, which in this study uses a discount rate of 9%. The value of the benefit-cost ratio (BCR) of the construction of this toll road is > 1, so the construction is worthwhile. Practicalimplications:Government support in the use of public funds for the development of marginal toll roads is needed so that the viability of an investment can be preserved, which will encourage further involvement of investors in the infrastructure development of roads, especially toll roads, in Indonesia, eventually becoming an accelerator of economic and regional growth. Authenticity/Value: The association is committed to creating a sense of safety, comfort, and smoothness for road users by making efforts to comply with the Minimum Service Standards (SPM) continuously established by the Government in this regard through the Directorate of JBH-DJBM Ministry of PUPR, as well as striving to meet the level of customer satisfaction through surveys carried out on a regular basis, inter alia by adding guidance lamps, building weighing bridges, improving rest area facilities, and traffic management activities in conjunction with the police and other relevant parties.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"81 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PATIENT SAFETY GOALS, AFRICA: DEVELOPMENT OF A CONTEXT FITTING TOOL FOR PATIENT SAFETY AND CARE QUALITY ASSESSMENT IN AFRICA USING THE DECIDE(HUMAN FACTORS) MODEL.","authors":"","doi":"10.46344/jbino.2024.v13i03.16","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.16","url":null,"abstract":"Patient safety practice refers to processes or structures which when applied, reduce the probability of adverse events resulting from exposure to the healthcare system across a range of diseases and procedures. It aims at making health care safer for both clients and staff (Kohn, Corrigan, & Donaldson, 2000). It is “A framework of organized activities that createcultures, processes, procedures, behaviours, technologies and environments in health care that consistently and sustainably lower risks, reduce the occurrence of avoidable harm, make errors less likely and reduce the impact of harm when it does occur.” (WHO, 2021). Quality of care is “the degree to which health services for individuals and populations increase the likelihood of desired health outcomes and are consistent with current professional knowledge” (IOM, 1990 and ahrq.gov., 2016). Healthcare quality is a level or value provided by any healthcare resource, as determined by some measurement (Maxwell, 1984).As with quality in other fields, it is an assessment of whether something is good enough and whether it is suitable for its purpose. Other definitions of healthcare quality include: “the degree of conformity with accepted principles and practices (standards), the degree of satisfying the patient’s needs, and the degree of attainment of acceptable outcomes, while making appropriate use of resources.” The Joint Commission defines care quality as “the optimal achievement of therapeutic benefit and avoidance of risk and minimization of harm”. Care quality is also referred to as freedom from deficiencies and therefore less costly because deficiencies which often lead to customer dissatisfaction require additional costs to manage them. Quality care conforms to relevant requirements or standards - the needs and expectations of clients or patients.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"113 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OVERVIEW OF ANEMIA AFTER SCOLIOSIS SURGERY IN THE INTENSIVE CARE UNIT (ICU) SOEHARSO ORTHOPEDIC HOSPITALINDONESIA","authors":"","doi":"10.46344/jbino.2024.v13i03.15","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.15","url":null,"abstract":"Anemia is a condition where the hemoglobin concentration is lower than normal. This condition reflects the lack of the normal number of erythrocytes in the body's circulation and consequently the amount of oxygen delivered to the body's tissues is also reduced. Miller & Thompson (2019) scoliosis comes from the Greek word \"scoliosis\" which means crooked. Scoliosis is a complex three-dimensional deformity of the spine characterized by a lateral deviation of at least 10 degrees with spinal rotation and is usually associated with a reduction in the normal kyphotic curvature of the spine / hypokyphosis. The cause of bleeding in spinal surgery usually occurs more in cases of rigid scoliosis, pedicle subtraction osteotomy and vertebral column resection often referred to as triple column osteotomy and is considered a procedure with a high risk of complications with massive blood loss, reaching more than 10 liters (Jun. 2019). Based on its classification, this type of research is retrospective descriptive research. studies that discuss one or more variables separately, one-by-one, but do not examine the relationship between these variables, using the observation method with the subject being observed by looking at past conditions (Harlan &Sutjiati, 2022). Using total sampling technique in sampling, the population is the medical records of patients admitted to the ICU, postoperative diagnosis of scoliosis with anemia, the sample size is 58 patient medical records. The variables observed were: indications for ICU admission and postoperative scoliosis, the inclusion criteria were medical record data for postoperative scoliosis patients with anemia admitted to the ICU for the period January 1 - December 31, 2022 and patients with the first scoliosis surgery. Based on this study, the following results were obtained: Most respondents were female (81%), the average age of respondents was 17 years. The most common type of scoliosis is adolescence idiopathic scoliosis (89.7%). The most Lenke classification is Lenke 3 (44.8%), the most types of surgery are stabilization, fusion, discectomy, laminectomy and osteotomy (56.9%). The duration of surgery was mostly 180-240 minutes (46.6%) with an average duration of surgery of 257 minutes, the average amount of bleeding was 884.5 ml, the average preoperative Hb was 13.3g/dL, the average postoperative Hb was 8.8 g/dL. The average postoperative Hemoglobin decrease was 5.3 g/dL, patients who were given blood transfusions (87.9%) with an average of 2.9 bags per patient, the most common type of transfused blood was PRC (90.2%).","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"65 s300","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MIRACULOUS APPROACH TO INCREASE HIGH DENSITY LIPOPROTEIN CHOLESTEROL BY CONSUMPTION OF FRUIT","authors":"","doi":"10.46344/jbino.2024.v13i03.08","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.08","url":null,"abstract":"Raised blood cholesterol is one of the important risk factor to develop coronary artery disease (CAD) leading to main cause of mobidity and mortality due to heart attck and cardiac arrhythmias. Decreased level of plasma HDL-cholesterol, independently can cause CAD. Recent research studies have proved that walnuts can increase plasma HDL-cholesterol if taken in specific amount per day regularly. Research study was conducted at Lahore General Hospital, Lahore from January 2023 to April 2023. Forty hyperlipidemic patients were selected from Lahore General Hospital for the study. Age of patients ranged from 20 to 65 years. Both gender male and female patients were enrolled. They were advised to discontinue any hypolipidemic medications and foods. Patients suffering from any metabolic disease, renal impairment, liver disease, and already having any cardiac problems were excluded from the research study. Forty patients were divided in two groups, twenty individuals in each group. Group-1 was advised to take 30 grams of walnuts (without shell) per day for the period of eight weeks. Group-II was considered as control group and was advised not to take any dry fruit including walnuts. Their baseline values of HDL-cholesterol were measured at day-0 and day-60, by separating other lipoprotein fractions using chemical precipitation with Mg2+, then coupling the products of a cholesterol oxidase reaction. In twenty hyperlipidemic patients, two months therapy with 30 grams of walnuts per day increase in HDL-cholesterol was 6.3 mg/dl which was significant change when analyzed biostatistically, showing p-value <0.01. Statistical analysis: Mean values with SD and SEM were analysed statistically by using SPSS version 16.1. P-value of <0.001 was considred as significant and p-value of >0.05 was considered as non-significant change. Conclusion: It was concluded from the study that regular intake of specific amount of walnuts without shell can increase good cholesterol (HDL-cholesterol) in male and female patients of age range from 18 to 65 years.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BIOMIMICRY: A BOON TO ENGINEERING AND TECHNOLOGY","authors":"","doi":"10.46344/jbino.2024.v13i03.03","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.03","url":null,"abstract":"Biomimicry is an ideology that imitates ideas from nature. Organisms in the natural environment have evolved and well adapted by structure and materials over geological time through natural selection. Many successful innovative ideas are harvested from the phenomenological approach to nature. Biomimicry is one of the elite approaches to challenge engineering problems in a sustainable manner. Biomimicry is currently being applied to build more efficient designs and sustainable technologies that harmonize with nature.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"46 S220","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TESTICULAR TORSION: PREOPERATIVE MEAN PLATELET VOLUME (MPV) AND LEUCOCYTE COUNT","authors":"","doi":"10.46344/jbino.2024.v13i03.12","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.12","url":null,"abstract":"Testicular torsion can occur at any age but commonly occurs soon after birth or between the ages of 12–18 years with a peak in incidence at age 13–14 years.The early recognition of testicular torsion has been associated with an increase in the rates of testicular salvage and the prevention of complications such as testicular infarction and infertility. This paper discusses predisposing factors, patient presentation, detection strategies including predictive scoring, differential diagnosis, diagnostic modalities, management options and medicolegal aspects pertaining to patients presenting with suspected testicular torsion in relation to mean platelet volume and leucocyte count.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"49 S244","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ROLE OF MANYAGATA SIIRAVYADHA (EXT. JUGULAR VEIN )AND SHAMANA AUAUSHADHI IN THE MANAGEMENT OF MUKHADUSHIKA - A CASE STUDY","authors":"","doi":"10.46344/jbino.2024.v13i03.11","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.11","url":null,"abstract":"skin colour and texture is found the healthy state of the body reflects on the personality of a person.Acne vulgaris a chronic inflammatory disorders in adolescents consist of the pilosebaceous follicles. in Ayurveda it can be corrected with Mukhadushika which is explained by Acharya Sushruta under kshudra rogas and is considered as swatantra vyadhi in the Ayurvedic literature. Acharya has considered Siravedha Raktamokshana as half of all the therapeutic measures in Shalyatantra like Basti karma in Kayachikitsa . The surgical procedure of puncturing the vein for therapeutic purpose and thereby accomplishing the Raktamokshakana (blood letting) is one of the panchakarma therapies .it is choice of the treatment in all the rakta pradoshaja vikaras like Kushta , Mukhadushika. it is a common procedure for the management of different disease with vitiated rakta dosha .The role of diet and cigarette smoking in the condition is unclear and neither cleanliness nor exposure to sunlight appears to play apart. In both sexes, hormones called Androgens appear to be part of theunderlying mechanism, by causingincreased production of sebum. In the Ayurveda It is characterized by Shalmali kantaka sadrusha pidika on the face. Mukhadushika is also called as Tarunya pitika. The prevalence of Mukhadushika increasing day by day due to their fast lifestyle, consumption of food,constipation,latenight sleep, fast food, cold drinks leads to an imbalance in doshas which in turn affects the body as well as mind.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"111 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ALTERNATIVE THERAPIES FOR OXIDATIVE STRESS","authors":"","doi":"10.46344/jbino.2024.v13i03.07","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.07","url":null,"abstract":"Free radicals such as reactive oxygen species (ROS) induce oxidative stress and cause cellular damage due to lipid peroxidation. There are three important steps in lipid peroxidation, namely initiation, propagation and termination. Formation of reactive aldehydes such as MDA and 4-HNE takes place when there is a catabolism of lipid hydroperoxides. Hyperlipidemia especially LDL-cholesterol may lead to development of coronary artery disease causing morbidity or mortality due to cardiac arrhythmias. Conventional hypolipidemic drugs have unwanted effects. Herbal therapy for Hyperlipidemia is getting attention due to their less frequent side effects. In this study we have compared hypolipidemic effects of Gemfibrozil with Nigella sativa. Seventy five hyperlipidemic patients from Jinnah Hospital Lahore were enrolled for study. After getting consent all patients were divided in three groups comprising 25 patients in each group. Group 1 was on Nigella sativa, group 2 was on Gemfibrozil and third group was on placebo therapy. They were advised to take drugs for two months. After completion of study pretreatment and post treatment values of LDL cholesterol were analyzed statistically. In Nigella sativa group LDL cholesterol decreased from 191.14±3.45 to 159.40±2.98 mg/dl, means 31.7 mg/dl LDL reduction was observed when compared with placebo group. In Gemfibrozil group of patients LDL cholesterol decreased from 197.77±3.91 mg/dl to 159.62±2.20 mg/dl, means LDL reduction in mean values was 38.2 mg/dl, when compared with placebo group. These changes are highly significant with p-values of <0.001. We concluded from this study that alternative therapy by herbal medication is as effective as by allopathic medication. Key words: serum lipids, oxidative stress, lethality, toxicity.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"34 S135","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFECT OF VERONIAAMYGDALINA ON THE ACTIVITIES OF HEPATIC ENZYMES IN WISTAR ALBINO RAT FED WITH CRUDE OIL CONTAMINATED DIET","authors":"","doi":"10.46344/jbino.2024.v13i03.17","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.17","url":null,"abstract":"The present study was carried out to determine the effect of Veroniaamygdalina on the liver of rats fed with crude oil contaminated diet. Preliminary toxicity study was carried out to determine the concentration of bitter leaf and crude oil that could cause toxicity and was carried out using 24. healthy male albino rats that were grouped into 6 of 4 each: Group A animals were the control group fed with just 100g of feed and Group B animals were fed with 100g of feed and 5g of biter leaf; while group C were fed 100g of feed and 10g of bitter leaf, group D were fed 100g of feed 5g of bitter leaf and4ml of crude oil, group B were fed with 100 of feed 10g of bitter leaf and 4ml of crude oil and group F were fed with 100g of feed and 4ml of crude oil. All the plasma liver biomarker enzymesAST, ALT, ALP and ACP were significantly increased (P<0.05) in all the grouped rats i.e. group B to group F compared to the group A rats which were the ‘control but elevated levels of the liver biomarker enzymes were noticed in the group F rats fed with just crude oil contaminated diet. This is an indication of impaired liver function. Aggressiveness, loss of body hairs and weight was also noticed which are clear indications of toxicity.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"55 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PELVIC ORGAN PROLAPSE: A REVIEW","authors":"","doi":"10.46344/jbino.2024.v13i03.02","DOIUrl":"https://doi.org/10.46344/jbino.2024.v13i03.02","url":null,"abstract":"Pelvic organ prolapse (POP) is a common condition that can lead to genital tract dysfunction and diminished quality of life. The etiology of POP is multifactorial and each factor is not known but the proposed risk factors that remain controversial are macrosomia, prolonged second-stage labor, episiotomy among others however, the commonest risk factor cited is vaginal childbirth, signs and may Symptoms include descent of the cervix, anterior vaginal,vaginal bulging, pelvic pressure, POP is considered a disease state if reduction relieves the symptoms, restores unction, and improves quality of life.","PeriodicalId":228982,"journal":{"name":"Journal of Bio Innovation","volume":"92 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}