The Journal of Qazvin University of Medical Sciences最新文献

{"title":"تأثیر فعالیت ورزشی هوازی با محدودیت جریان خون بر پروتئینهای دینامیک میتوکندری عضله اسکلتی انسان","authors":"علی آریاشکیب, بهمن میرزایی, پیام سعیدی","doi":"10.32598/JQUMS.24.1.1","DOIUrl":"https://doi.org/10.32598/JQUMS.24.1.1","url":null,"abstract":"","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"2-13"},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrigenomics: A New Approach to Feed Formulation","authors":"S. R. Hashemi, H. Davoodi, Elnaz Arabiyan","doi":"10.32598/jqums.23.5.8","DOIUrl":"https://doi.org/10.32598/jqums.23.5.8","url":null,"abstract":"Nutrigenomics is the study of the effect of nutrition on gene expression which discusses how DNA is converted to mRNA and then converted mRNA to protein, and is the basis for understanding the biological activity of edible compounds. Nutritional manipulations and nutritional approaches are key tools to influence the performance and health of organisms. Today, it has been shown that better nutrition of animals selected for further production has a beneficial effect on their function. Despite the importance of this issue in production systems, there are no ways to clearly explain the molecular mechanisms of these changes. This review study aimed to investigate nutrigenomics as a molecular approach to the expression of genes involved in the health and growth of organisms. Searching was conducted in Scopus, PubMed, ScienceDirect, IranMedex, and Google Scholar databases on the studies conducted during 1990-2018 by using the keywords: “nutrigenomics”, “gene expression”, “nutrients”, “food formulation”. Initial stage yielded 120 articles. After excluding conferences papers, 58 remained for the final review. There are a limited number of nutrigenomics studies on the laboratory and farm animals, but it has been confirmed that there is an association between nutrition, genetics, fertility and growth. Therefore, the use of nutrients that can express gene expression in a way that improves the function and efficiency of organisms is essential in feed formulation as a new approach in nutrition.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Health Literacy and Self-efficacy of the Elderly","authors":"J. Azimian, F. Mohammadi, A. Javadi, Neda Asgarian","doi":"10.32598/JQUMS.23.5.3","DOIUrl":"https://doi.org/10.32598/JQUMS.23.5.3","url":null,"abstract":"Background Health literacy is the capacity of a person to obtain, process, and understand basic health \u0000information for appropriate health decision making. Self-efficacy is the assurance that is felt about a \u0000particular activity which maintains and promotes effective health behaviors. \u0000Objective The purpose of this study is to evaluate the relationship between health literacy and self-efficacy \u0000in the elderly people. \u0000Methods This descriptive-correlational study with cross-sectional design was conducted on 144 elderly \u0000living in Ramsar city in 2018 who were selected using a random cluster sampling method. Data collection \u0000tools were a demographic form, Self Rated Abilities for Health Practices Scale, and Health Literacy \u0000for Iranian Adults completed by the researcher after obtaining informed consent from the participants. \u0000Data were analyzed in SPSS v.16 software using correlation test, independent t-test, chi-square test, and \u0000Fisher’s exact test. \u0000Findings Most of participants were female (59%), married (86.8%), housekeeper (52.8%) and high school \u0000dropouts (35.4%), and moderate financial status (61.8%) with a mean age of 68.75±2.12 years. Pearson \u0000correlation test results showed a significant relationship between health literacy and self-efficacy of the \u0000elderly (P=0.0001). \u0000Conclusion Considering the role of health literacy in increasing the self-efficacy of the elderly, healthcare \u0000system policymakers need to pay attention to the issue of health literacy in health system planning.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"224-233"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47172505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Acceptance and Commitment Therapy and Positive Psychotherapy on Emotional Self-Regulation of Women With Coronary Heart Disease","authors":"Simin Sayafi, Nemat Sotodeh Asl, Morteza Ebrahimi Varkiani","doi":"10.32598/JQUMS.24.6.6","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.6","url":null,"abstract":"Background: Emotional self-regulation can play an important role in reducing the symptoms of coronary heart disease which is a psychosomatic disorder. Objective: This study aims to compare the effectiveness of Acceptance and Commitment Therapy (ACT) and positive psychotherapy on emotional self-regulation of women with coronary heart disease. Methods: This is a randomized clinical trial. Study population consists of all women with coronary heart disease referred to Pasteur Hospital in Qazvin, Iran during 2019-2020. Using a convenience sampling method, 45 women were selected and divided into three groups (two experimental groups and one control group). The intervention program was provided at 8 sessions for each experimental group. Data collection tools were a demographic form, and Ibanez’s Self-regulation Inventory. Participants were followed up for one month after intervention. Collected data were analyzed by ANCOVA and paired t-test. Findings: ACT was effective in increasing emotional self-regulation ability of patients in the post-test and follow-up phases, but the positive psychotherapy had no significant effect on their emotional self-regulation and no significant difference was observed. Conclusion: ACT is an appropriate and effective method for women with coronary heart disease and can be used as a complementary therapy in related medical centers.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"532-543"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42910688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Post-traumatic Growth in Patients With Myocardial Infarction","authors":"S. Golafshani, Farshad Taheri, H. Nia, Somayeh Minaeimoghaddam","doi":"10.32598/JQUMS.24.6.5","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.5","url":null,"abstract":"Background: Some people experience positive psychological changes in various aspects after a stressful event. These positive changes, known as Post-Traumatic Growth (PTG), are often due to people’s need to adapt to the challenges ahead. Objective: This study aims to determine the predictors of PTG in patients with myocardial infarction. Methods: This is a descriptive-correlational study. Participants were 191 patients with myocardial infarction referred to the cardiac clinic of Bu-Ali Sina Hospital in Qazvin, Iran. They were selected using a convenience sampling method and based on inclusion/exclusion criteria. The research instruments were the Post-Traumatic Growth Inventory (PTGI), Multidimensional Perceived Social Support Scale (MSPSS), and the Meaning in Life Questionnaire (MLQ). Collected data were analyzed in SPSS V. 25 software using Pearson correlation test and linear regression analysis. Findings: There was a significant positive relationship between PTG with perceived social support (r=0.47 and P<0.001) and meaning in life (r=0.71 and P<0.001). Based on the results of linear regression analysis, an increase in the scores of MSPSS and MLQ can increase the PTGI score by 0.978 and 1.376, respectively. Conclusion: This study provided important insights into the phenomenon of PTG in patients with myocardial infarction and its predictors, which can help improve PTG in them.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"520-531"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41322489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Trauma and Their Relationship With Pre-hospital Time Intervals in Patients Admitted to a Hospital in Qazvin, Iran","authors":"P. Namdar, Faranak Norian, Z. Yazdi, E. Modirian","doi":"10.32598/JQUMS.24.6.4","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.4","url":null,"abstract":"Background: Due to the importance of investigating the causes of trauma and functional indicators of pre-hospital emergency care. Objective: This study aims to evaluate the outcomes of trauma and their relationship with pre-hospital time intervals in patients admitted to Shahid Rajaei Hospital in Qazvin, Iran. Methods: In this descriptive study conducted in 2018, the medical records of 700 patients transported to Shahid Rajaei Hospital in Qazvin by Emergency Medical Services (EMS) ambulances were examined which were selected from 3200 cases using a systematic sampling method. We used a two-part questionnaire surveying demographic/clinical information of patients and their clinical outcomes. Findings: Mean age of patients was 33.8 years and 62% were male. Median of on-scene time, transport time, and total prehospital time were 7, 29.3 and 37 minutes, respectively. In overall, 72.4% of transferred patients were discharged from the emergency department, 19.7% admitted to other wards, and 4.4% discharged voluntarily. Conclusion: Time intervals of EMS in Qazvin city are suitable, and their provided pre-hospital services have acceptable quality.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"556-565"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49080652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunological and Clinical Aspects of Immune Responses to SARS-CoV-2","authors":"A. Andalib, Maedeh Radandish","doi":"10.32598/JQUMS.24.6.10","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.10","url":null,"abstract":"The Coronavirus Disease 2019 (COVID-19) caused by a coronavirus named SARS-CoV-2 from the family Coronaviridae, was first reported in December 2019 in China. The disease have mild or severe symptoms such as fever, chills, cough, shortness of breath, body aches, and gastrointestinal symptoms, followed by severe inflammation, cytokine storm, acute respiratory distress syndrome, and dysfunction of other organs. In this narrative review study, the search was conducted on related studies published during January- October 2020 in Google Scholar, PubMed, Embase, and Scopus databases using the keywords Covid-19, Immunology, and Immunopathogenesis. Among abundant and mostly repetitive information, the immunological aspects were selected. The SARS-CoV-2 can enter the cell by binding to the Angiotensin-Converting Enzyme 2 (ACE2) receptor and Trans-Membrane Protease Serine 2 (TMPRSS2) on the surface of lung epithelial cells. The main pathogenic mechanism of infection with SARS-CoV-2 is the stimulation of inflammatory response followed by damage to the alveoli of lung tissue. In uncontrolled immune responses, the infiltration of macrophages, monocytes, neutrophils, and inflammatory T cells into the alveoli increases which leads to tissue damage in the lungs and other organs by overproduction of inflammatory cytokines such as Interleukin 6 (IL-6), Tumor Necrosis Factor alpha (TNF-α), Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Interleukin 6 (IL-8), Interferon gamma (IFNγ), etc. The Natural Killer (NK) and T cell dysfunction, lymphopenia, and infection of immune cells such as monocytes with ADE mechanism are factors causing the body’s failure in resistance to SARS-CoV-2 virus. Diagnosis of COVID-19 is based on the clinical symptoms and the results of molecular tests (e.g. Polymerase Chain Reaction test), or computerized tomography scan followed by serological tests and measuring biochemical factors in the blood (e.g. lymphocyte count, C-reactive protein, dimerized plasmin fragment D, etc.). Due to the association of the severity of COVID-19 with the uncontrolled immune response of the host, targeting any of the immunopathological pathways to inhibit inflammatory responses can be considered as potential therapeutic goals. The use of immune system regulators such as chloroquine, corticosteroids, inflammatory cytokine blockers such as anti-IL-6, anti-IL-1, and cell therapy at the right time have an enhanced effect on the recovery of the disease or inhibit the disease progression.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45508883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between the -1031 (T/C) Polymorphism of TNF-α Gene and Biochemical Factors in Women With Polycystic Ovary Syndrome","authors":"M. Sahmani, T. D. Ghaleh, Maryam Yargholi, Farshad Foroghi, A. Javadi, Khadijeh Taherkhani","doi":"10.32598/JQUMS.24.6.1","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.1","url":null,"abstract":"Background: Tumor Necrosis Factor Alpha (TNF-α) gene, as an inflammatory factor, plays an important role in reproductive physiology, especially in women with Polycystic Ovary Syndrome (PCOS). Objective: This study aims to investigate the relationship between the -1031 T/C polymorphism of TNF-α gene and biochemical factors in women with PCOS. Methods: In this case-control study, participants were 106 women with PCOS and 114 healthy women referred to Kosar Hospital in Qazvin, Iran. The TNF-α gene’s polymorphism was determined using Polymerase Chain Reaction (PCR) technique and PCR-Restriction Fragment Length Polymorphism (PCR-RFLP) method. Biochemical factors of serum levels were also measured in two groups. Logistic regression analysis examined the relationship between the frequency of alleles in different states and the risk of PCOS. Findings: There were statistically significant difference in the mean levels of total cholesterol, triglycerides, testosterone, two-hour blood glucose and body mass index between the groups, whose values were higher in women with PCOS compared to healthy women (P<0.001). In women with PCOS, the mean serum levels of triglyceride and high-density lipoprotein were significantly different between the three TT, CC, TC genotypes of TNF-α gene polymorphism (P<0.05). The results of regression analysis showed that the TT genotype had significant association with the risk of PCOS (OR=2.43, P=0.006, 95%CI: 1.28-2.62). Conclusion: It seems that there is a relationship between the -1301 (T/C) polymorphism of TNF-α gene and the risk of PCOS in women.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"486-497"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44827965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Accuracy of Diagnosis and Treatment Made by Pre-hospital Emergency Medical Technicians in Patients Admitted to Hospitals in Qazvin, Iran","authors":"P. Namdar, A. Kazemifar, M. Mohammadi","doi":"10.32598/JQUMS.24.6.3","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.3","url":null,"abstract":"Background: Correct diagnosis and appropriate treatment measures of pre-hospital Emergency Medical Technicians (EMTs) are very important in improving the quality of patient care and reducing mortality and costs. Objective: This study aims to investigate the accuracy of diagnosis and treatment made by pre-hospital EMTs in patients admitted to hospitals in Qazvin, Iran. Methods: In this descriptive study conducted in 2018, the medical records of 600 patients who were transferred to Bu-Ali Sina and Velayat hospitals in Qazvin by ambulance during March-June 2018 were examined. Diagnosis and treatment measures were extracted from the emergency sheet. Education, work experience, and amount of in-service training of pre-hospital EMTs were also collected. Data were analyzed in SPSS V. 23 software using ANOVA, Chi-square test, and t-test. Findings: Out of 600 cases, 71.7% of the initial diagnoses made by EMTs were correct, 8.5% were incorrect, and 19.8% were without initial diagnosis. Regarding the treatment measures, 65.8% were correct and 3.5% were incorrect. Conclusion: Prompt help and correct diagnostic and treatment measures of pre-hospital EMTs can significantly reduce mortality and potential injuries.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"510-519"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41379781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repeated Transcranial Magnetic Stimulation and Nursing Care: A Review","authors":"M. Amini, R. Zeighami","doi":"10.32598/JQUMS.24.6.9","DOIUrl":"https://doi.org/10.32598/JQUMS.24.6.9","url":null,"abstract":"Repeated Transcranial Magnetic Stimulation (RTMS) therapy is one of the modern treatment methods for various neurological and psychiatric diseases. With the clinical advancement of new therapies, there is a need to increase nursing knowledge, various practical skills, and new ways of organizing care. This study aims to review the rTMS, and the role of psychiatric nurses before, during and after rTMS. The search was conducted in IranMedex, PubMed, Elsevier, Google Scholar, Ovid, and SID databases using the keywords: Repeated transcranial magnetic stimulation, long-term potential, mental nerve, psychiatric nursing both in English and Persian. Initial search yielded 42 articles, of which 24 were selected for the review. Treatment with rTMS can cause significant treatment effects. It has low complications, and is non-invasive and painless. The patient is conscious during the treatment process and is safe from the effects of anesthetic drugs. This method is also effective for people who are resistant to treatment. The psychiatric nurses play an important role in rTMS and teach patients on the formation of realistic expectations and the establishment of systems that ensure the continuity of safety and care. Moreover, they can assess clinical problems and work with the patients to create a therapeutic environment.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":"24 1","pages":"582-591"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49530671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}