Nutrigenomics: A New Approach to Feed Formulation

S. R. Hashemi, H. Davoodi, Elnaz Arabiyan
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引用次数: 1

Abstract

Nutrigenomics is the study of the effect of nutrition on gene expression which discusses how DNA is converted to mRNA and then converted mRNA to protein, and is the basis for understanding the biological activity of edible compounds. Nutritional manipulations and nutritional approaches are key tools to influence the performance and health of organisms. Today, it has been shown that better nutrition of animals selected for further production has a beneficial effect on their function. Despite the importance of this issue in production systems, there are no ways to clearly explain the molecular mechanisms of these changes. This review study aimed to investigate nutrigenomics as a molecular approach to the expression of genes involved in the health and growth of organisms. Searching was conducted in Scopus, PubMed, ScienceDirect, IranMedex, and Google Scholar databases on the studies conducted during 1990-2018 by using the keywords: “nutrigenomics”, “gene expression”, “nutrients”, “food formulation”. Initial stage yielded 120 articles. After excluding conferences papers, 58 remained for the final review. There are a limited number of nutrigenomics studies on the laboratory and farm animals, but it has been confirmed that there is an association between nutrition, genetics, fertility and growth. Therefore, the use of nutrients that can express gene expression in a way that improves the function and efficiency of organisms is essential in feed formulation as a new approach in nutrition.
营养基因组学:饲料配方的新方法
营养基因组学是研究营养对基因表达的影响,探讨DNA如何转化为mRNA,然后将mRNA转化为蛋白质,是了解可食用化合物生物活性的基础。营养操作和营养方法是影响生物性能和健康的关键工具。今天,研究表明,为进一步生产选择更好的动物营养对它们的功能有有益的影响。尽管这个问题在生产系统中很重要,但没有办法清楚地解释这些变化的分子机制。本综述旨在探讨营养基因组学作为研究生物健康和生长相关基因表达的分子方法。在Scopus、PubMed、ScienceDirect、IranMedex和谷歌Scholar等数据库中检索1990-2018年间的相关研究,检索关键词为“营养基因组学”、“基因表达”、“营养素”、“食品配方”。初始阶段有120篇文章。除去会议论文后,还有58篇有待最后审查。对实验室和农场动物进行的营养基因组学研究数量有限,但已经证实营养、遗传、生育和生长之间存在联系。因此,利用能够表达基因表达的营养物质来提高生物体的功能和效率,是饲料配方中必不可少的一种营养新途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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