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Highlights in traumatic brain injury research in 2024 2024年外伤性脑损伤研究重点
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00477-0
Virginia Newcombe, Elisa R Zanier
{"title":"Highlights in traumatic brain injury research in 2024","authors":"Virginia Newcombe, Elisa R Zanier","doi":"10.1016/s1474-4422(24)00477-0","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00477-0","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in neuromuscular disorders 2024 神经肌肉疾病进展2024
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00489-7
Jeffrey D Rothstein, Ahmet Hoke, Payam Mohassel
{"title":"Advances in neuromuscular disorders 2024","authors":"Jeffrey D Rothstein, Ahmet Hoke, Payam Mohassel","doi":"10.1016/s1474-4422(24)00489-7","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00489-7","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in sleep research in 2024 2024年睡眠研究进展
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00486-1
Yves Dauvilliers
{"title":"Advances in sleep research in 2024","authors":"Yves Dauvilliers","doi":"10.1016/s1474-4422(24)00486-1","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00486-1","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress and future directions in spinal cord injury trials 脊髓损伤试验的进展和未来方向
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00482-4
Karlo M Pedro, Michael G Fehlings
{"title":"Progress and future directions in spinal cord injury trials","authors":"Karlo M Pedro, Michael G Fehlings","doi":"10.1016/s1474-4422(24)00482-4","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00482-4","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infectious diseases research in 2024: insights into dementia 2024年的传染病研究：对痴呆症的洞察
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00497-6
Robyn S Klein
{"title":"Infectious diseases research in 2024: insights into dementia","authors":"Robyn S Klein","doi":"10.1016/s1474-4422(24)00497-6","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00497-6","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cristina Sampaio: bringing rigour to research in movement disorders 克里斯蒂娜·桑帕约：为运动障碍研究带来严谨
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00434-4
Udani Samarasekera
{"title":"Cristina Sampaio: bringing rigour to research in movement disorders","authors":"Udani Samarasekera","doi":"10.1016/s1474-4422(24)00434-4","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00434-4","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to Lancet Neurol 2024; 23: 1205–13 柳叶刀神经杂志2024；23日:1205 - 13所示
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00495-2
{"title":"Correction to Lancet Neurol 2024; 23: 1205–13","authors":"","doi":"10.1016/s1474-4422(24)00495-2","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00495-2","url":null,"abstract":"<em>Sheth KN, Albers GW, Saver JL, et al. Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial.</em> Lancet Neurol <em>2024; <strong>23:</strong> 1205–13</em> —In this Article, the CHARM Trial investigators and the appendix have been updated. This correction has been made as of Dec 18, 2024.","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyotrophic lateral sclerosis caused by SOD1 variants: from genetic discovery to disease prevention 由 SOD1 变异引起的肌萎缩侧索硬化症：从基因发现到疾病预防
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00479-4
Michael Benatar, Janice Robertson, Peter Munch Andersen
{"title":"Amyotrophic lateral sclerosis caused by SOD1 variants: from genetic discovery to disease prevention","authors":"Michael Benatar, Janice Robertson, Peter Munch Andersen","doi":"10.1016/s1474-4422(24)00479-4","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00479-4","url":null,"abstract":"Pathogenic variants in the superoxide dismutase 1 (<em>SOD1</em>) gene were the first identified genetic cause of amyotrophic lateral sclerosis (ALS), in 1993. This discovery enabled the development of transgenic rodent models for studying the biology of <em>SOD1</em> ALS. The understanding that <em>SOD1</em> ALS is driven by a toxic gain-of-function mutation has led to therapeutic strategies that aim to lower concentrations of SOD1 protein, an endeavour that has been complicated by the phenotypic heterogeneity of <em>SOD1</em> ALS. The successful development of genetically targeted therapies to reduce SOD1 expression, together with a better understanding of pre-symptomatic disease and the discovery of neurofilament light protein as a susceptibility/risk biomarker that predicts phenoconversion, has ushered in a new era of trials that aim to prevent clinically manifest <em>SOD1</em> ALS. The 30-year journey from gene discovery to gene therapy has not only uncovered the pathophysiology of <em>SOD1</em> ALS, but has also facilitated the development of biomarkers that should aid therapy development for all forms of ALS.","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"260 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging the diagnostic gap in Alzheimer's disease 弥合阿尔茨海默病的诊断差距
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00490-3
{"title":"Bridging the diagnostic gap in Alzheimer's disease","authors":"","doi":"10.1016/s1474-4422(24)00490-3","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00490-3","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Headache research in 2024: new data on migraine prevention 2024年的头痛研究：偏头痛预防的新数据
The Lancet Neurology Pub Date : 2024-12-18 DOI: 10.1016/s1474-4422(24)00485-x
Patricia Pozo-Rosich
{"title":"Headache research in 2024: new data on migraine prevention","authors":"Patricia Pozo-Rosich","doi":"10.1016/s1474-4422(24)00485-x","DOIUrl":"https://doi.org/10.1016/s1474-4422(24)00485-x","url":null,"abstract":"No Abstract","PeriodicalId":22676,"journal":{"name":"The Lancet Neurology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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