The Egyptian Journal of Surgery最新文献

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Outcomes of revisional surgery for stenosed hepaticojejunostomy procedures 狭窄肝空肠吻合术翻修手术的结果
The Egyptian Journal of Surgery Pub Date : 2024-03-22 DOI: 10.4103/ejs.ejs_324_23
Bashir A. Fadel, Tameem M. Ibraheem, Waleed A. Hassan, Amira E. Mohammed, Mahmoud Moubark, Mahoud H.E.A. Elrazik
{"title":"Outcomes of revisional surgery for stenosed hepaticojejunostomy procedures","authors":"Bashir A. Fadel, Tameem M. Ibraheem, Waleed A. Hassan, Amira E. Mohammed, Mahmoud Moubark, Mahoud H.E.A. Elrazik","doi":"10.4103/ejs.ejs_324_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_324_23","url":null,"abstract":"\u0000 \u0000 Although hepaticojejunostomy provides durable and efficient access for bilioenteric continuity, it is not free from complications, as stenosis could occur in 25% of cases. Radiologically guided interventions are the best options for managing stenosed anastomoses. However, about 30% of stenosed patients show failure. Thus, surgical intervention (redo) is a must in such circumstances. Herein, we describe the outcomes of redo surgery for patients diagnosed with stenosed hepaticojejunostomy after failed radiological interventions.\u0000 \u0000 \u0000 \u0000 During the study period, we encountered 52 patients with stenosed hepaticojejunostomy, from whom 20 cases showed failed radiological intervention, and they were enrolled in our study, and their data were collected and retrospectively reviewed.\u0000 \u0000 \u0000 \u0000 The primary procedure was performed for cholecystectomy-related biliary injury (80%), choledochal cyst (15%), and as a step of the Whipple procedure (5%). All patients presented with jaundice, while 25% of them had cholangitis. Radiological assessment showed Bismuth class I, II, III, and IV in 20, 45, 25, and 10%, respectively. The time interval between the primary and the redo procedure ranged between 6 months and 5 years. Operative time ranged between 110 and 150 min, and hospital stay ranged between 4 and 10 days. Postoperative complications included bile leakage (5%), pulmonary embolism (5%), wound infection (20%), and incisional hernia (10%). No patients developed restenosis during the follow-up period. History of cholangitis was a significant risk factor for postoperative morbidity.\u0000 \u0000 \u0000 \u0000 Revisional procedures for stenosed hepaticojejunostomy are considered safe and efficacious. The safety is manifested in the accepted complication rate, while the efficacy is manifested in the excellent success rate. However, it should be preserved only for patients with failed radiological interventions.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140214268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One-stage versus two-stage procedure for the surgical management of patients with acute mesenteric ischemia 急性肠系膜缺血患者手术治疗的一段式与两段式手术比较
The Egyptian Journal of Surgery Pub Date : 2024-03-22 DOI: 10.4103/ejs.ejs_323_23
Mohamed Abd Allah Abd Elhady, Mohamed Khidr Mohamed, Mohamed Hafez, Mohamed Mostafa Mahmoud
{"title":"One-stage versus two-stage procedure for the surgical management of patients with acute mesenteric ischemia","authors":"Mohamed Abd Allah Abd Elhady, Mohamed Khidr Mohamed, Mohamed Hafez, Mohamed Mostafa Mahmoud","doi":"10.4103/ejs.ejs_323_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_323_23","url":null,"abstract":"\u0000 \u0000 Damage control surgery (planned second look) is preferred by many surgeons in the management of patients with acute mesenteric ischemia (AMI) with established bowel necrosis. However, some surgeons prefer to perform primary anastomosis during the first operation, making the second look only when indicated. Herein, we compare the perioperative outcomes of the previous two approaches in AMI patients.\u0000 \u0000 \u0000 \u0000 In this prospective, randomized study, AMI was diagnosed in 74 patients who were divided into group A (one-stage approach) and group B (two-stage approach).\u0000 \u0000 \u0000 \u0000 The one-stage approach spent more operative time compared with the first step of the other approach (110 vs. 70 min, respectively). The planned second look had an average of 75 min, and intestinal resection was done in 35.14% of cases due to advancing ischemia. The incidence of leakage was higher in the one-stage group (32.43%) compared with the other (5.4%), leading to a high reoperation rate in the former. ICU stay was longer with the damage control approach. Nonetheless, no difference was detected regarding the hospitalization period. The one-stage approach was associated with a higher 30-day mortality rate (29.73 vs. 8.11% in the other group). Risk factors for mortality included shock at presentation, prolonged operative time, and postoperative leakage.\u0000 \u0000 \u0000 \u0000 The application of the damage control approach in patients with AMI is of great benefit as it is associated with low leakage rates, less need for reoperation, and less incidence of 30-day mortality compared with the one-stage approach.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140217872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of bariatric surgery on obstructive sleep apnea: using the STOP-Bang score as a screening tool 减肥手术对阻塞性睡眠呼吸暂停的影响:使用 STOP-Bang 评分作为筛查工具
The Egyptian Journal of Surgery Pub Date : 2024-03-22 DOI: 10.4103/ejs.ejs_262_23
Mohamed Khattab, Goerge A. E. F. Nashed, Mostafa M. Abdelfatah, Malek M. M. Mahmoud, Mohamed Saber Mostafa
{"title":"Effect of bariatric surgery on obstructive sleep apnea: using the STOP-Bang score as a screening tool","authors":"Mohamed Khattab, Goerge A. E. F. Nashed, Mostafa M. Abdelfatah, Malek M. M. Mahmoud, Mohamed Saber Mostafa","doi":"10.4103/ejs.ejs_262_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_262_23","url":null,"abstract":"\u0000 \u0000 Obstructive sleep apnea (OSA), the most prevalent major sleep disorder in the world, has been associated with obesity. Besides reducing weight, bariatric surgery has been reported to improve OSA. Data on the effects of bariatric surgery on OSA are scarce in Egypt. This study aimed to evaluate the short-term effects of bariatric surgery on OSA.\u0000 \u0000 \u0000 \u0000 This is a prospective study that was conducted on patients who were candidates for bariatric surgery at our institution who completed the STOP-Bang questionnaire before the surgery with a score greater than or equal to 4 and underwent re-evaluation 6 months after surgery. All patients underwent a standardized clinical assessment. The 6-month follow-up data were recorded and analyzed.\u0000 \u0000 \u0000 \u0000 The present study included 30 patients, with a mean baseline BMI of 54.32±9.77 kg/m2. The surgeries performed were Laparoscopic Sleeve Gastrectomy (LSG) (n=21, 70%) and Laparoscopic Roux en Y gastric bypass (LRYGB) (n=9, 30%). The mean baseline STOP-Bang score was 5.3±1.09. At the 6-month follow-up, the mean 6-month postoperative STOP-Bang score was 1.13±1.04 (P<0.001). No statistically significant differences were noted in the BMI or the STOP-Bang score before and after surgery according to the surgery type (P>0.05). There was a statistically significant positive correlation between the 6-month BMI reduction and the Snoring, Tiredness, Observed apnea, Pressure, BMI, Age, Neck, Gender (STOP-Bang) score improvement (r=0.397, P=0.0298).\u0000 \u0000 \u0000 \u0000 This study demonstrated the bariatric surgery-initiated evident improvement and even complete resolution of OSA in patients with obesity, as measured by the STOP-Bang score.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140218231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The controversy of management of left-sided colon obstructions: our experience 左侧结肠梗阻治疗的争议:我们的经验
The Egyptian Journal of Surgery Pub Date : 2024-03-22 DOI: 10.4103/ejs.ejs_295_23
S. Saber, Tamer M. Elmahdy, S. Elgarf, A. Swelam, Gamal Mousa, Mahmoud A. Eissa
{"title":"The controversy of management of left-sided colon obstructions: our experience","authors":"S. Saber, Tamer M. Elmahdy, S. Elgarf, A. Swelam, Gamal Mousa, Mahmoud A. Eissa","doi":"10.4103/ejs.ejs_295_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_295_23","url":null,"abstract":"\u0000 \u0000 The controversy of treatment of acute colonic obstruction between the classical Hartmann’s procedure (HP) and the on-table lavage technique with primary colorectal anastomosis (PCA) for a safe, tolerable, and definitive operation with the least complications is still standing. So we conducted this prospective study to distinguish between both techniques as regards the efficacy and safety.\u0000 \u0000 \u0000 \u0000 In group A (n _ 30) the conventional Hartmann’s procedure was done by colonic resection and construction of left-sided stoma. In the B group (n _ 30), colonic resection was followed by colonic lavage, then a primary two-layered anastomosis with covering ileostomy was performed.\u0000 \u0000 \u0000 \u0000 The whole postoperative outcomes were comparable between both techniques.\u0000 \u0000 \u0000 \u0000 We believe that on table lavage technique with colorectal anastomosis is a notable choice during the treatment of acute obstruction of the left colon.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140218796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strangulated groin hernia prognosis in adults in sub-Saharan African context: Retrospective study at Zinder, Niger 撒哈拉以南非洲成人腹股沟绞窄疝的预后:尼日尔津德尔的回顾性研究
The Egyptian Journal of Surgery Pub Date : 2024-02-22 DOI: 10.4103/ejs.ejs_253_23
H. Adamou, Ibrahim Magagi Amadou, O. Adakal, Abdel Nasser M. Hamidou, M. Hassane, L. J. Didier, Rachid Sani
{"title":"Strangulated groin hernia prognosis in adults in sub-Saharan African context: Retrospective study at Zinder, Niger","authors":"H. Adamou, Ibrahim Magagi Amadou, O. Adakal, Abdel Nasser M. Hamidou, M. Hassane, L. J. Didier, Rachid Sani","doi":"10.4103/ejs.ejs_253_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_253_23","url":null,"abstract":"\u0000 \u0000 In our context, hernial strangulation has a high incidence. The aim of this work was to investigate prognostic factors in adults diagnosed with strangulated groin hernia.\u0000 \u0000 \u0000 \u0000 This was a retrospective cross-sectional study conducted at Zinder National Hospital between 1 January 2016 and 31 December 2022 (7 years). Clinical and prognostic data were collected.\u0000 \u0000 \u0000 \u0000 Out of 568 patients who underwent surgery for groin hernia, 230 cases were strangulated (40.49%). Mean age was 47.8±16.6 years. The proportion of males was 86.65%, i.e. the sex ratio was 5.96. Inguinal hernia accounted for 85.2% (n=196). The median operative time was 7 h. The Bassini procedure was the most common with 83.5% (n=192). Small bowel was the content of the hernia sac in 80% (n=184). Intestinal necrosis occurred in 10.9% (n=25). This was associated with femoral location (OR=5.39, P=0.00003). Intestinal resection was performed in 13.9% (n=32) and stoma in 1.7% (n=4). Postoperative complications occurred in 25.2% (n=58). The overall mortality (grade V) was 6.5% (n=15). Mortality was statistically associated with age > 60 years (OR=5.16; P=0.0016), admission time (OR=3.20; P=0.028), time to surgery > 8 h (OR=4.20; P=0.005) and occurrence of necrosis (OR=9.39; P=0.000).\u0000 \u0000 \u0000 \u0000 Strangulated groin hernia is a common surgical emergency. Its prognosis is associated with advanced age, femoral location, and diagnostic and therapeutic delay.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140439825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of anterior component separation technique on lowering the incidence of abdominal wall dehiscence and incisional hernia after emergent laparotomy: a feasibility study 前部组件分离技术对降低急诊开腹手术后腹壁开裂和切口疝发生率的影响:一项可行性研究
The Egyptian Journal of Surgery Pub Date : 2024-01-01 DOI: 10.4103/ejs.ejs_238_23
Mahmoud Aziz, Ahmed Elghrieb, Mohamed E. Abdu, Mohamed M. Mahmoud
{"title":"Impact of anterior component separation technique on lowering the incidence of abdominal wall dehiscence and incisional hernia after emergent laparotomy: a feasibility study","authors":"Mahmoud Aziz, Ahmed Elghrieb, Mohamed E. Abdu, Mohamed M. Mahmoud","doi":"10.4103/ejs.ejs_238_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_238_23","url":null,"abstract":"\u0000 \u0000 Abdominal wall dehiscence is one of the critical postoperative complications following abdominal surgeries. Emergency surgery highly contributes to the incidence of a burst abdomen due to a lack of proper preoperative preparation and the presence of intraabdominal sepsis. Anterior component separation was primarily evolved in abdominal wall reconstruction in the open abdomen and huge ventral hernia repair.\u0000 \u0000 \u0000 \u0000 This prospective study included 50 patients operated by midline laparotomy for non-traumatic abdominal emergencies. Anterior component separation technique was randomly applied in 25 patients before laparotomy closure, the other 25 patients were closed using the traditional midline closure method. Preoperative patient’s demographics, operative time, and different postoperative complications were reported. Incidence of burst abdomen in both groups was reported.\u0000 \u0000 \u0000 \u0000 Preoperative patient’s demographic data showed no significant difference between both groups; the mean age of the patients was 53.69±7.34. Operative time was significantly longer in the Anterior Components Separation (ACS) group (P<0.001). The incidence of abdominal wall dehiscence after ACS technique (4.3%) was significantly less than after traditional technique (24%). Postoperative seroma and hematoma were the common postoperative complications after ACS however the incidence was not statistically significant. Incisional hernia was detected in (13.04%) in ACS group and in (32%) in traditional group.\u0000 \u0000 \u0000 \u0000 Application of ACS technique during laparotomy closure in abdominal emergencies seems to lower the incidence of abdominal wall dehiscence with no increase in different postoperative complications.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140517822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extended Totally Extraperitoneal (eTEP) Technique vs. Laparoscopic Intraperitoneal Onlay Mesh (IPOM) in Ventral Hernia Repair: A Randomized Comparative Study 腹股沟疝气修补术中腹膜外延伸(eTEP)技术与腹腔镜腹膜内嵌网(IPOM)的随机比较研究:随机比较研究
The Egyptian Journal of Surgery Pub Date : 2024-01-01 DOI: 10.4103/ejs.ejs_242_23
Tarek M. Sehsah, Ahmed A. Elshora, O. Abd-Raboh
{"title":"Extended Totally Extraperitoneal (eTEP) Technique vs. Laparoscopic Intraperitoneal Onlay Mesh (IPOM) in Ventral Hernia Repair: A Randomized Comparative Study","authors":"Tarek M. Sehsah, Ahmed A. Elshora, O. Abd-Raboh","doi":"10.4103/ejs.ejs_242_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_242_23","url":null,"abstract":"\u0000 \u0000 Repairing of ventral and incisional hernias is a frequently performed surgical intervention in the field of general surgery; this work aimed to compare the extended totally extraperitoneal (eTEP) technique to the intraperitoneal onlay mesh (IPOM) technique for ventral hernias regarding feasibility, cost, operative, and postoperative outcomes of both techniques.\u0000 \u0000 \u0000 \u0000 This randomized controlled study was conducted on 50 patients complaining of ventral hernia. These patients were admitted to Tanta University Hospitals, Egypt, from January 2021 to January 2023. Patients were divided according to the technique used into two2 equal groups: group eTEP (study group): 25 participants were submitted to eTEP repair. Group IPOM (control group): 25 patients were submitted to IPOM repair.\u0000 \u0000 \u0000 \u0000 Demographic data were insignificantly different between both groups. Operation time was significantly prolonged in group eTEP compared to group IPOM (P<0.001). Cost and hospital stay were significantly decreased in group eTEP compared with group IPOM (P<0.05). Pain at rest and restriction to normal activity were significantly lower on the first and 14th postoperative days in group eTEP compared with group IPOM (P<0.05). Cosmesis was insignificantly different on the first and 14th postoperative days between both groups. Postoperative seroma, postoperative recurrence, and postoperative ileus were insignificantly different between both groups.\u0000 \u0000 \u0000 \u0000 Both eTEP and IPOM demonstrated safety and efficacy in the treatment of de-novo ventral hernia repair (comparable few complications in both groups with no recurrence in this study) with superiority toward eTEP as evidenced by lower hospital stay, cost, postoperative pain, and early return to normal activity.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140517994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adding quilting sutures to Y plasty to avoid postmastectomy lateral dog ears in patients with large cup sized breast 在 Y 形乳房成形术中加入绗缝,避免大罩杯乳房患者在乳房切除术后出现侧犬耳
The Egyptian Journal of Surgery Pub Date : 2024-01-01 DOI: 10.4103/ejs.ejs_270_23
M. Alhussini, A. Awad, Hassan Kholosy
{"title":"Adding quilting sutures to Y plasty to avoid postmastectomy lateral dog ears in patients with large cup sized breast","authors":"M. Alhussini, A. Awad, Hassan Kholosy","doi":"10.4103/ejs.ejs_270_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_270_23","url":null,"abstract":"\u0000 \u0000 Total mastectomy without reconstruction is a commonly adopted procedure for managing breast cancer. Formation of lateral dog ears is very common, especially with large breast cup size. In this study, we assessed the feasibility of adding quilting sutures to the Y plasty technique to achieve more acceptable results in the avoidance of lateral dog ears in comparison to using Y plasty alone.\u0000 \u0000 \u0000 \u0000 The study included 150 female patients with large breast cup size. Patients were randomized 2 : 1 between group A and group B. In group A, 3–5 quilting sutures were added to the lateral flaps of Y plasty. In group B, Y plasty only was adopted without the quilting sutures. Patients were followed up at 4-month intervals for at least 1 year. One year after surgery, patients filled in a questionnaire inquiring about the degree of discomfort in the area beneath the arm. Also, a plastic surgeon was asked to give a score about the cosmetic outcome of managing lateral dog ears both at 3 weeks and 12 months after surgery.\u0000 \u0000 \u0000 \u0000 Both groups were comparable in regard to age, BMI, breast cup size, and postoperative radiotherapy exposure. Patients in group A had better scores for satisfaction with the shape of the scar and comfort with the bra. Also, the blinded cosmetic outcome assessment was in favor of group A.\u0000 \u0000 \u0000 \u0000 Adding quilting sutures to the lateral flap of the V-Y plasty technique is associated with a better cosmetic outcome in the management of lateral dog ears in mastectomy patients with large breast cup size.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rectal cancer complete responders after neoadjuvant chemoradiation: when to spare their organs? 新辅助化疗后完全应答的直肠癌患者:何时保留其器官?
The Egyptian Journal of Surgery Pub Date : 2024-01-01 DOI: 10.4103/ejs.ejs_235_23
Ahmed M. Saleh, Mohamed Mazloum, Abdelsalam Ismail, Doaa Emara
{"title":"Rectal cancer complete responders after neoadjuvant chemoradiation: when to spare their organs?","authors":"Ahmed M. Saleh, Mohamed Mazloum, Abdelsalam Ismail, Doaa Emara","doi":"10.4103/ejs.ejs_235_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_235_23","url":null,"abstract":"\u0000 \u0000 The aim of this study is to identify possible clinical predictors of complete response after neoadjuvant treatment (NAT) in locally advanced rectal cancer (LARC) patients.\u0000 \u0000 \u0000 \u0000 This study included 40 LARC patients (16 males and 24 females) who received NAT followed by total mesorectal excision (TME) in the period between August 2020 and February 2023. Two different NAT protocols were used; long-course chemoradiotherapy (LCRT) or consolidation total neoadjuvant treatment (TNT) according to the decision of the multidisciplinary team (MDT). Reassessment of response is done after completion of radiotherapy by digital rectal examination (DRE), proctoscopy, and pelvic MRI to define complete responders. All these responders received TME and were classified according to their pathology specimens into the pathological complete response group (pCR=22 patients) and nonpathological complete response group (non-pCR=18 patients). Statistical analyses were performed to compare the two groups and identify clinical factors associated with pCR.\u0000 \u0000 \u0000 \u0000 The significant clinical predictors of pCR in the univariate analysis were patients’ age, preneoadjuvant carcinoembryonic antigen (CEA) level and preneoadjuvant lymphocytic ratio (P=0.030, 0.007, and 0.001, respectively). In multivariate analysis, lymphocytic ratio was the only independent predictor for pCR (P=0.017). Lymphocytic ratio (>26%) has high diagnostic performance for predicting pCR, while age (>50 years) and normal CEA (≤5 ng/ml) have lower diagnostic performance which can be much improved when both are used in combination to predict pCR.\u0000 \u0000 \u0000 \u0000 Preneoadjuvant lymphocytic ratio and the combined use of age and preneoadjuvant CEA level are significant predictors of pCR, this may help the MDT select rectal cancer patients with complete clinical response (cCR), who are candidates for organ preserving strategies, to spare their rectum and avoid unnecessary radical surgeries.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Vacuum Assisted Closure Therapy and Nano-Silver Coated Dressing on Wound Healing in Patients with Diabetic Foot Wound: A Randomized Prospective Trial 真空辅助闭合疗法与纳米银涂层敷料对糖尿病足患者伤口愈合的影响比较:随机前瞻性试验
The Egyptian Journal of Surgery Pub Date : 2024-01-01 DOI: 10.4103/ejs.ejs_248_23
Amr A.H. Mahmoud, Abdel R.K. Mahmoud, Khalid Z. Mansour, Mohamed I.M. Ismail
{"title":"Comparison of Vacuum Assisted Closure Therapy and Nano-Silver Coated Dressing on Wound Healing in Patients with Diabetic Foot Wound: A Randomized Prospective Trial","authors":"Amr A.H. Mahmoud, Abdel R.K. Mahmoud, Khalid Z. Mansour, Mohamed I.M. Ismail","doi":"10.4103/ejs.ejs_248_23","DOIUrl":"https://doi.org/10.4103/ejs.ejs_248_23","url":null,"abstract":"\u0000 \u0000 Diabetic foot ulcers constitute one of the most important complications of diabetes mellitus. If not treated promptly, progression of infection and sepsis may necessitate a limb amputation.\u0000 \u0000 \u0000 \u0000 To assess wound healing and to assess the time for wound healing of diabetic foot ulcers using vacuum-assisted closure (VAC) in comparison with nano-silver coated dressing.\u0000 \u0000 \u0000 \u0000 This was a simple randomized cohort prospective trial included two groups of postoperative diabetic foot patients, in which we had a comparison between VAC and nano-silver dressing in order to investigate which procedures had the least time of follow up weeks for full granulation of wound.\u0000 \u0000 \u0000 \u0000 VAC significantly reduces the time to complete wound healing by enhancement the formation of granulation tissue.\u0000 \u0000 \u0000 \u0000 The time to complete wound healing was significantly better in the VAC therapy group as compared with nano-silver dressing.\u0000","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140516320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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