Comparison of Vacuum Assisted Closure Therapy and Nano-Silver Coated Dressing on Wound Healing in Patients with Diabetic Foot Wound: A Randomized Prospective Trial

Abstract

Diabetic foot ulcers constitute one of the most important complications of diabetes mellitus. If not treated promptly, progression of infection and sepsis may necessitate a limb amputation. To assess wound healing and to assess the time for wound healing of diabetic foot ulcers using vacuum-assisted closure (VAC) in comparison with nano-silver coated dressing. This was a simple randomized cohort prospective trial included two groups of postoperative diabetic foot patients, in which we had a comparison between VAC and nano-silver dressing in order to investigate which procedures had the least time of follow up weeks for full granulation of wound. VAC significantly reduces the time to complete wound healing by enhancement the formation of granulation tissue. The time to complete wound healing was significantly better in the VAC therapy group as compared with nano-silver dressing.