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Betel nut sweets present growing health threat to children 槟榔糖对儿童的健康威胁越来越大
The BMJ Pub Date : 2025-05-30 DOI: 10.1136/bmj.r1050
William J Moss, Michelle Hermiston, Saman Warnakulasuriya
{"title":"Betel nut sweets present growing health threat to children","authors":"William J Moss, Michelle Hermiston, Saman Warnakulasuriya","doi":"10.1136/bmj.r1050","DOIUrl":"https://doi.org/10.1136/bmj.r1050","url":null,"abstract":"Urgent legislative action is needed to protect minors Areca nut, also known as betel nut, is the fibrous seed of the Areca catechu palm and has been consumed throughout the Asia-Pacific for thousands of years.1 The nut is chewed and placed in the buccal cavity, where psychoactive agents are absorbed trans-mucosally. Users experience a mild psychostimulant effect from arecoline, a muscarinic receptor agonist that induces alertness, body warmth, and, for some, a slight euphoria. Chewing customs vary by region, with many preferring to wrap the nut in a plant leaf along with tobacco and slaked lime (calcium hydroxide) to increase its potency. Betel nut use is prevalent in populous Asian countries such as China and India, as well as remote island nations scattered throughout Micronesia and Melanesia. As a result of population migration, it is increasingly available worldwide, including in metropolitan areas throughout Europe and North America. Globally, betel nut consumption is most common among marginalised communities, many of which have limited access to higher education.1 The assortment of betel nut products …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brazil’s teen pregnancy rate is plummeting: what can other countries learn from it? 巴西的青少年怀孕率正在急剧下降:其他国家能从中学到什么?
The BMJ Pub Date : 2025-05-30 DOI: 10.1136/bmj.r852
Luke Taylor
{"title":"Brazil’s teen pregnancy rate is plummeting: what can other countries learn from it?","authors":"Luke Taylor","doi":"10.1136/bmj.r852","DOIUrl":"https://doi.org/10.1136/bmj.r852","url":null,"abstract":"Teenage pregnancies in Brazil have been stubbornly high for decades, but a range of efforts to tackle this inequality are finally bearing results. Luke Taylor reports For decades Brazil has struggled to bring down its stubbornly high rate of teenage pregnancy. The country has nearly twice as many adolescent births as the average upper middle income nation, and its absolute numbers are enormous owing to a population of 210 million. In 2015 alone 547 000 Brazilian mothers aged under 20 gave birth, 26 000 of them girls under 15.12 Adolescent births are driven by inequality and perpetuate it—so, in a nation as unequal as Brazil, this is one of the country’s largest health and socioeconomic issues. High rates of teenage pregnancy disproportionately affect the poorest communities, where they worsen already limited educational and economic opportunities for young mothers and increase the risk of maternal and infant health complications. Both the covid pandemic and ongoing moves to water down sex education in recent years have sparked fears that Brazil could take a step backwards, leading to more girls getting married, dropping out of school, or losing their lives in clandestine abortion clinics. “It really is a public health crisis,” says Denise Leite Maia Monteiro, who heads the Brazilian Association of Obstetrics and Gynecology for Childhood and Adolescence. “If we want to achieve the [World Health Organization’s] sustainable development goals by 2030 we need to combat inequalities and invest in implementing policies focused on adolescent sexual and reproductive health.” Despite such fears, however, recent figures suggest that Brazil is achieving a remarkable turnaround. The number of births among adolescent girls has halved in just a decade. Some 286 000 Brazilian girls aged 10-19 gave birth in the first half of 2014, but in the same period in 2024 the figure was 141 000. This …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial 胸腺素α1治疗脓毒症的疗效和安全性(测试):多中心、双盲、随机、安慰剂对照、3期试验
The BMJ Pub Date : 2025-05-30 DOI: 10.1136/bmj.r1098
British Medical Journal Publishing Group
{"title":"The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial","authors":"British Medical Journal Publishing Group","doi":"10.1136/bmj.r1098","DOIUrl":"https://doi.org/10.1136/bmj.r1098","url":null,"abstract":"Some of the data in this paper by Wu and colleagues ( BMJ 2025;388:e082583, doi:10.1136/bmj-2024-082583, published 15 January 2025) have been updated. Disruptions to clinical service during the covid-19 pandemic affected the data verification process at some of the trial centres leading to inaccurate data being entered …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A brief history of discharge summaries . . . and other research 出院总结简史…还有其他研究
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj.r1027
Tom Nolan
{"title":"A brief history of discharge summaries . . . and other research","authors":"Tom Nolan","doi":"10.1136/bmj.r1027","DOIUrl":"https://doi.org/10.1136/bmj.r1027","url":null,"abstract":"Tom Nolan reviews this week’s research Giving a hearing aid to people with untreated hearing loss helps them retain one additional person in their social network over a three year period. This catchy finding from a secondary analysis of the ACHIEVE study seems ripe for being widely cited as evidence that we can make a big difference to patients’ lives by getting the basics right. Unfortunately, it’s unclear how much of a difference to loneliness and social isolation it actually makes: after three years, people in the hearing aid arm of the study still had a social network size of 21.3 people (over a two week period), down from 22.6. The control group’s social network dropped …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical facial rash in systemic lupus erythematosus 系统性红斑狼疮的非典型面部皮疹
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj-2024-082188
Xiaoyuan Hou, Jia Chen
{"title":"Atypical facial rash in systemic lupus erythematosus","authors":"Xiaoyuan Hou, Jia Chen","doi":"10.1136/bmj-2024-082188","DOIUrl":"https://doi.org/10.1136/bmj-2024-082188","url":null,"abstract":"This woman in her early 30s with an 11 year history of systemic lupus erythematosus (SLE) experienced a sudden disease flare-up with symptoms of SLE encephalopathy. She was treated with methylprednisolone (500 mg daily for three days, then reduced to 40 mg daily), hydroxychloroquine (200 mg orally twice daily), and …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying opportunities for progress 识别进步的机会
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj.r1099
Tom Moberly
{"title":"Identifying opportunities for progress","authors":"Tom Moberly","doi":"10.1136/bmj.r1099","DOIUrl":"https://doi.org/10.1136/bmj.r1099","url":null,"abstract":"Health services are struggling to maintain progress made over decades in reducing the incidence of preventable illnesses. Cases of gonorrhoea are increasing, even though condoms are effective at preventing its transmission, with infections becoming more complex and treatment resistant strains becoming more common (doi:10.1136/bmj-2025-084789).1 Infant mortality in the UK is rising, even though many of these deaths could be avoided with better support for public health (doi:10.1136/bmj.r1053).2 UK deaths from cardiovascular disease in working age adults are now also on the rise, after falling …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal exposure to cannabis . . . and other stories 产前接触大麻…还有其他的故事
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj.r1021
British Medical Journal Publishing Group
{"title":"Prenatal exposure to cannabis . . . and other stories","authors":"British Medical Journal Publishing Group","doi":"10.1136/bmj.r1021","DOIUrl":"https://doi.org/10.1136/bmj.r1021","url":null,"abstract":"In a trial in hospitals in Finland, 90 patients with recurring or complicated diverticulitis were randomised either to elective sigmoid resection or to conservative treatment ( JAMA Surg doi:10.1001/jamasurg.2025.0572). During four years of follow-up, a third of patients allocated to conservative treatment needed surgery because of persistently poor quality of life. By contrast, early surgery prevented recurrence of diverticulitis without increasing complications. Living close to a golf course increases …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nairobi’s poorest areas hit hardest as aid cuts complicate emergency medicine problems 由于援助削减使急诊医疗问题复杂化,内罗毕最贫困地区受到的打击最为严重
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj.r986
Frank Burkybile
{"title":"Nairobi’s poorest areas hit hardest as aid cuts complicate emergency medicine problems","authors":"Frank Burkybile","doi":"10.1136/bmj.r986","DOIUrl":"https://doi.org/10.1136/bmj.r986","url":null,"abstract":"Most of the population in Kenya’s capital live in informal settlements, which emergency services are increasingly struggling to reach. Frank Burkybile reports On the night of 16 January 2023, a devastating fire swept through Maasai village in Mukuru, one of Nairobi’s largest informal settlements, destroying more than 300 homes and displacing more than 1000 families.1 Emergency response vehicles, including ambulances and fire engines, took several hours to arrive, impeded by confusing directions, narrow and unpaved roads, and difficulty accessing the neighbourhood because of limited entry points for vehicles.1 Residents themselves became first responders, highlighting systemic failures in Nairobi’s emergency medical services that disproportionately affect the capital city’s resource poor areas. More than two years later, these structural challenges remain unresolved. Over 60% of Nairobi’s population of nearly five million live in unplanned and overcrowded informal settlements.2 Although the city is home to leading hospitals and medical specialists, residents of these densely populated areas often lack timely access to emergency medical care. Ambulances typically arrive within eight minutes in affluent neighbourhoods, whereas response times in large, congested informal settlements in Nairobi, such as Kibera, Mukuru, and Mathare, often exceed an hour, significantly increasing the number of fatalities. …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"1 1","pages":"r986"},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Michael Modell: GP, researcher, and teacher who pioneered medical education in primary care in face of academic scepticism 迈克尔·莫德尔:全科医生、研究员和教师,他在面对学术怀疑时开创了初级保健医学教育
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj.r1054
Anne Gulland
{"title":"Michael Modell: GP, researcher, and teacher who pioneered medical education in primary care in face of academic scepticism","authors":"Anne Gulland","doi":"10.1136/bmj.r1054","DOIUrl":"https://doi.org/10.1136/bmj.r1054","url":null,"abstract":"When Michael Modell was at University College London (UCL) in the 1950s, the time that students spent in the community was generally limited to a half day when they were bussed between a general practice, a delousing centre, and the public baths at St Pancras. Modell, the son of a GP, was unusual in that he chose to spend two weeks in a practice in Kentish Town, north London, one of whose partners was John Horder. Horder, often called the founding father of modern general practice, had a huge influence on Modell. What Modell observed in Horder were “high quality clinical skills, an open approach to the patient, and involvement of the student in the consultation.” Modell joined Horder’s practice on completing his training and was a conscientious and risk averse GP. He would only refer a patient, particularly a child, to hospital if it was absolutely necessary. If he had made a house call to a child with a rash or fever earlier in the day he would often come up with a spurious excuse to return to check up on them later. His interest in paediatrics led him to write a book on child health in the community. He would even visit his young patients in hospital, where he made an impression on house officer Bernadette McLoughlin. These visits led to a closer working collaboration between Modell’s practice …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the complexities of mild and moderate covid-19 treatment 应对covid-19轻度和中度治疗的复杂性
The BMJ Pub Date : 2025-05-29 DOI: 10.1136/bmj.r1016
Mohammad Bosaeed, Basem M Alraddadi
{"title":"Navigating the complexities of mild and moderate covid-19 treatment","authors":"Mohammad Bosaeed, Basem M Alraddadi","doi":"10.1136/bmj.r1016","DOIUrl":"https://doi.org/10.1136/bmj.r1016","url":null,"abstract":"Interpreting evidence from different stages of the pandemic is challenging Covid-19 remains an active global public health concern, with ongoing transmission in most countries. Despite considerable progress in global vaccination coverage and natural immunity development, covid-19 infections and emerging variants continue to cause clinical challenges.1 According to the latest update from the World Health Organization (WHO), SARS-CoV-2 is most likely transitioning towards endemicity in some regions of the world, particularly in areas with low vaccination coverage or waning immunity.1 Mild or moderate covid-19 infections, defined as cases not requiring oxygen treatment or hospital admission, represent the bulk of SARS-CoV-2 infections globally.2 Key strategies for treating mild or moderate covid-19 include supportive care measures such as antipyretics, analgesics, and adequate hydration and rest. Adjunctive treatments, such as zinc, vitamin D, and other immune supportive supplements, were commonly used, although the evidence for their effectiveness is mixed.34 For individuals at high risk, recommendations suggest certain antiviral medications that can be given early to mitigate disease severity.56 These recommendations and guidelines have evolved …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144165463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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