THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019最新文献

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In vitro and in silico study to evaluate the effectiveness of quercitrin as antiviral drug to dengue virus 体外和计算机研究评价槲皮素作为登革热病毒抗病毒药物的有效性
B. Dewi, E. Ratningpoeti, H. Desti, M. Angelina
{"title":"In vitro and in silico study to evaluate the effectiveness of quercitrin as antiviral drug to dengue virus","authors":"B. Dewi, E. Ratningpoeti, H. Desti, M. Angelina","doi":"10.1063/1.5139341","DOIUrl":"https://doi.org/10.1063/1.5139341","url":null,"abstract":"Dengue Fever (DF) in Indonesia has been a major health problem for the last 47 years, which keeps on rising until today. Quercitrin as one of the natural compounds, flavonol group and has been used in several types of research for their properties of anti-inflammation, anti-bacterial, anti-viral, and anti-fungi. The aim of this study was to explore the potency of quercitrin as an antiviral drug to dengue virus (DENV) in vitro and in silico. We used Focus assay, MTT assay, and docking analysis to determine IC50, CC50 and binding energy, respectively. The IC50, CC50 and Selectivity Index (SI) of quercitrin was 1.1 µg/ml, 38.8 µg/ml and 38 respectively. In silico study showed the binding energy between quercitrin and NS5 protein was −7,54 kkal/mol. The results obtained that Quercutrin as a good candidate for an antiviral drug to DENV in the future.Dengue Fever (DF) in Indonesia has been a major health problem for the last 47 years, which keeps on rising until today. Quercitrin as one of the natural compounds, flavonol group and has been used in several types of research for their properties of anti-inflammation, anti-bacterial, anti-viral, and anti-fungi. The aim of this study was to explore the potency of quercitrin as an antiviral drug to dengue virus (DENV) in vitro and in silico. We used Focus assay, MTT assay, and docking analysis to determine IC50, CC50 and binding energy, respectively. The IC50, CC50 and Selectivity Index (SI) of quercitrin was 1.1 µg/ml, 38.8 µg/ml and 38 respectively. In silico study showed the binding energy between quercitrin and NS5 protein was −7,54 kkal/mol. The results obtained that Quercutrin as a good candidate for an antiviral drug to DENV in the future.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88588418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Numerical study of optimization performance induced draft fan through openings setting the inlet guide vane 通过设置进口导叶来优化引风机性能的数值研究
Yanuar Rulyanto, H. Mirmanto
{"title":"Numerical study of optimization performance induced draft fan through openings setting the inlet guide vane","authors":"Yanuar Rulyanto, H. Mirmanto","doi":"10.1063/1.5138289","DOIUrl":"https://doi.org/10.1063/1.5138289","url":null,"abstract":"Boiler is an important part of the Steam Power Plant. One of the combustion systems in the boiler is using the balance draft method, where combustion air conditions in the furnace supplied by Force Draft Fan (FDF), and residual combustion air (exhaust gas) are sucked with Induced Draft Fan (IDF) by maintaining the -30 Pa pressure furnace accordingly manufacturer’s standard. Furnace has not been able to achieve ideal conditions, because the performance of Induce Draft Fan (IDF) has less optimal suction power. This is allegedly from the opening of the Inlet Guide Vane which is not yet optimal. The test model in the form of Induce Draft Fan is simulated using CFD modeling software. The dimensions of the inlet guide vane, rotor, and static blade are carried out by 3D scanning. While for the casing model uses the manufacturer’s reference image. The results of this study are expected to improve IDF performance by determining the variation of the damper opening (IGV opening angle) optimally. From CFD simulation, pressure suction becomes more vacuum by opening the IGV from −10°, 0°, 10°, 40°, The value of the IDF pressure suction is −100 = −2494.7 Pa, 0° = −3129.5 Pa, 10° = −3398.2 Pa, 40° = −4425.2 Pa. Based on CFD simulations, the optimal damper opening is at 40°. At 41° opening of Inlet Guide Vane, the IDF suction ability decreases, This is indicated by the suction ability at −4249.4 Pa. Considering the process of setting the Inlet Guide Vane opening angle on the Induce Draft Fan requires a shutdown unit and production opportunities will disappear and the costs are relatively large, the performance optimization process is carried out using simulation.Boiler is an important part of the Steam Power Plant. One of the combustion systems in the boiler is using the balance draft method, where combustion air conditions in the furnace supplied by Force Draft Fan (FDF), and residual combustion air (exhaust gas) are sucked with Induced Draft Fan (IDF) by maintaining the -30 Pa pressure furnace accordingly manufacturer’s standard. Furnace has not been able to achieve ideal conditions, because the performance of Induce Draft Fan (IDF) has less optimal suction power. This is allegedly from the opening of the Inlet Guide Vane which is not yet optimal. The test model in the form of Induce Draft Fan is simulated using CFD modeling software. The dimensions of the inlet guide vane, rotor, and static blade are carried out by 3D scanning. While for the casing model uses the manufacturer’s reference image. The results of this study are expected to improve IDF performance by determining the variation of the damper opening (IGV opening angle) optimally. From CFD simulation,...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"33 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89916890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oil immersion technique for cellular microencapsulation 细胞微胶囊化的油浸技术
R. Nurhayati, W. Mubarok, Rafianto Dwi Cahyo, Kamila Alawiyah
{"title":"Oil immersion technique for cellular microencapsulation","authors":"R. Nurhayati, W. Mubarok, Rafianto Dwi Cahyo, Kamila Alawiyah","doi":"10.1063/1.5139325","DOIUrl":"https://doi.org/10.1063/1.5139325","url":null,"abstract":"Recent advances in tissue engineering application for medical intervention has created a need for three-dimensional (3D) cellular microenvironment in the form of cellular microencapsulation. Cellular microencapsulation can be used in several applications such as in vitro drug screening as well as cellular transplantation. It is important to note, however, that despite all the benefit from the cells, the capsule itself also has a major role. Significant impact and even clinical risks can present if the capsule is not biocompatible or even toxic. Hence, careful consideration on the materials and more importantly the fabrication process of the capsule is needed. In this work, we presented a method for cellular encapsulation using oil immersion technique. Briefly, suspension of K562 cells and collagen was injected into the mineral oil on a cell strainer. Microcapsule then washed with PBS and immersed with culture medium. Photomicrograph analysis was performed to evaluate the shape as well as to measure the volume of the microcapsule. Immunohistochemistry staining with Propidium Iodide (PI) was used to confirm K562 entrapment within the microcapsule. Cellular microencapsulation using oil immersion technique resulted in a rounded sphere. The increased volume of cells-hydrogel suspension resulted in bigger diameter and volume of the capsule. Due to the nature of the immersion process, a layer of oil could be found outside the capsule. The volume of the oil on the border of the capsule also increased with higher hydrogel-cells suspension. PI-stained K562 cells were found within the microcapsule, confirming that K562 cells were indeed entrapped within the microcapsule. In conclusion, oil immersion technique provides a quick, easy, and feasible method to produce cellular microencapsulation","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78191809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chitosan-alginate matrices loaded with leaf extracts of Anredera cordifolia Steenis as a gastrointestinal extended-release formulation 壳聚糖-海藻酸盐基质负载堇青花叶提取物作为胃肠道缓释制剂
E. Krisanti, Mutiara Primaster Wahyunisa, Nugrahirani Hijrianti, K. Mulia
{"title":"Chitosan-alginate matrices loaded with leaf extracts of Anredera cordifolia Steenis as a gastrointestinal extended-release formulation","authors":"E. Krisanti, Mutiara Primaster Wahyunisa, Nugrahirani Hijrianti, K. Mulia","doi":"10.1063/1.5139338","DOIUrl":"https://doi.org/10.1063/1.5139338","url":null,"abstract":"The development of chitosan-alginate matrices loaded with Anredera cordifolia Steenis (Madeira-vine) leaf extract as an extended-release formulation is herewith described. Madeira-vine plants have been known used traditionally to treat various ailments such as anti-inflammation, hypertension, and skin diseases. The matrices were prepared using the ionotropic gelation methodwith tripolyphosphate as the cross-linking agent. Scanning electron microscope and Fourier transform infrared spectroscopy was used to investigate the surface morphology and the structure of the matrices, respectively. The effect of alginate addition was studied by determining the physical characteristics of the matrices, encapsulation efficiency, loading capacity, matrix yield, as well as the release profiles of the bioactive compounds in simulated gastrointestinal fluids. The bioactive compounds in the leaf extracts and matrices, quantified as total phenolics, were determined using UV-spectrophotometry. High-performance liquid chromatography was used to determine the amount of vitexin present in the leaf extracts. The encapsulation efficiency of the phenolic compounds was at least 90%, the highest loading capacity was 1.23%, and matrix yield was at least 83%. The in vitro release assays showed a reduced cumulative release of phenolic compounds in synthetic gastric fluid (35 to 12%), and, in three synthetic gastrointestinal fluids (71 to 50%) after 24 hours, due to the addition of alginate in the chitosan matrix. These results indicate the possibility of employing chitosan-alginate matrixto shift the release of phenolics of Anredera cordifolia extracts from the gastric area to the colon area.The development of chitosan-alginate matrices loaded with Anredera cordifolia Steenis (Madeira-vine) leaf extract as an extended-release formulation is herewith described. Madeira-vine plants have been known used traditionally to treat various ailments such as anti-inflammation, hypertension, and skin diseases. The matrices were prepared using the ionotropic gelation methodwith tripolyphosphate as the cross-linking agent. Scanning electron microscope and Fourier transform infrared spectroscopy was used to investigate the surface morphology and the structure of the matrices, respectively. The effect of alginate addition was studied by determining the physical characteristics of the matrices, encapsulation efficiency, loading capacity, matrix yield, as well as the release profiles of the bioactive compounds in simulated gastrointestinal fluids. The bioactive compounds in the leaf extracts and matrices, quantified as total phenolics, were determined using UV-spectrophotometry. High-performance liquid chromat...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78479602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
CFD analysis on temperature homogenisation performance in experimental power reactor bottom plenum 实验动力堆底充气室温度均匀性的CFD分析
R. A. P. Dwijayanto, Farisy Yogatama Sulistyo, M. Subekti
{"title":"CFD analysis on temperature homogenisation performance in experimental power reactor bottom plenum","authors":"R. A. P. Dwijayanto, Farisy Yogatama Sulistyo, M. Subekti","doi":"10.1063/1.5135530","DOIUrl":"https://doi.org/10.1063/1.5135530","url":null,"abstract":"An issue concerning Experimental Power Reactor (Reaktor Daya Eksperimental/RDE), an HTGR-based experimental-scale nuclear power reactor proposed by National Nuclear Energy Agency (Badan Tenaga Nuklir Nasional/BATAN), is hot gas temperature deviation. To prevent safety-related problems caused by such deviation, RDE employs two levels of gas mixing for the heated coolant gas; the first level is bottom plenum and the second is hot gas chamber. Unlike the latter, bottom plenum is a simple empty column where the heated gas is mixed, but not homogeneous enough to be considered safe to be flown into the heat exchanger. To understand the mixing phenomena better, this paper will analyse the temperature homogenisation on the RDE bottom plenum, employing computational fluid dynamics-based method using FLUENT software. Simulation result shows that the coolant gas heterogeneity is reduced by 139.98°C, implying temperature homogeneity degree of 55.99%. This value provides insight on coolant gas parameter to perform more accurate calculation on the hot gas chamber. Temperature deviation pattern at the outlet channels is also discussed.An issue concerning Experimental Power Reactor (Reaktor Daya Eksperimental/RDE), an HTGR-based experimental-scale nuclear power reactor proposed by National Nuclear Energy Agency (Badan Tenaga Nuklir Nasional/BATAN), is hot gas temperature deviation. To prevent safety-related problems caused by such deviation, RDE employs two levels of gas mixing for the heated coolant gas; the first level is bottom plenum and the second is hot gas chamber. Unlike the latter, bottom plenum is a simple empty column where the heated gas is mixed, but not homogeneous enough to be considered safe to be flown into the heat exchanger. To understand the mixing phenomena better, this paper will analyse the temperature homogenisation on the RDE bottom plenum, employing computational fluid dynamics-based method using FLUENT software. Simulation result shows that the coolant gas heterogeneity is reduced by 139.98°C, implying temperature homogeneity degree of 55.99%. This value provides insight on coolant gas parameter to perform mor...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73084971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrohydrodynamic drying process of the amoxicillin powder using a high direct current (DC) voltage 利用直流高压对阿莫西林粉末进行电液干燥
Nicholas, T. Abuzairi
{"title":"Electrohydrodynamic drying process of the amoxicillin powder using a high direct current (DC) voltage","authors":"Nicholas, T. Abuzairi","doi":"10.1063/1.5139385","DOIUrl":"https://doi.org/10.1063/1.5139385","url":null,"abstract":"Electrohydrodynamic drying (EHD) processes have been applied in many experiments. However, EHD rarely applied to drying medications, specifically medical powders. The EHD process reduces the water level of materials through a coronal wind by placing them between two electrodes that conduct a strong electric field. In this study, EHD is applied using needles with copper plates as the two electrodes. Within the same surface area, different numbers of needles (2×2, 3×3, and 4×4) are arranged to conduct the positive charge using the copper plate as the grounding system. By using various numbers of needles and modifying the gap between them and the material, the effect of the EHD process on the material, namely amoxicillin powder, is determined. Based on the experimental results, a 2×2 needle arrangement and 2-cm gap between the needles and the sample have the fastest drying speed as compared to other needle numbers and gaps.Electrohydrodynamic drying (EHD) processes have been applied in many experiments. However, EHD rarely applied to drying medications, specifically medical powders. The EHD process reduces the water level of materials through a coronal wind by placing them between two electrodes that conduct a strong electric field. In this study, EHD is applied using needles with copper plates as the two electrodes. Within the same surface area, different numbers of needles (2×2, 3×3, and 4×4) are arranged to conduct the positive charge using the copper plate as the grounding system. By using various numbers of needles and modifying the gap between them and the material, the effect of the EHD process on the material, namely amoxicillin powder, is determined. Based on the experimental results, a 2×2 needle arrangement and 2-cm gap between the needles and the sample have the fastest drying speed as compared to other needle numbers and gaps.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"123 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76264974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Analysis of MOD-1 heating section efficiency in the RCCS test facility of high temperature reactors 高温反应堆RCCS试验装置MOD-1加热段效率分析
H. Tjahjono, R. Kusumastuti, M. Juarsa, D. Haryanto, S. Widodo, A. S. Ekariansyah, Susyadi, M. Kusuma
{"title":"Analysis of MOD-1 heating section efficiency in the RCCS test facility of high temperature reactors","authors":"H. Tjahjono, R. Kusumastuti, M. Juarsa, D. Haryanto, S. Widodo, A. S. Ekariansyah, Susyadi, M. Kusuma","doi":"10.1063/1.5135531","DOIUrl":"https://doi.org/10.1063/1.5135531","url":null,"abstract":"In order to develop the design of Reactor Cavity Cooling System (RCCS) from High Temperature Reactors (HTRs), Center for Nuclear Reactor Technology and Safety (PTKRN) has built an RCCS experimental facility aimed for supporting the development of methods in designing a RCCS for a larger scale. This facility refers to the basic design of the RCCS of a 10 MWth Non-Commercial Power Reactor (RDNK) with a scale of 1/1 for height and 1/15 scale for width. With the availability of this experimental facility, characterization needs to evaluate whether the facility has functioned as planned. Especially for heating section, the initial design made called the Mod-1 is a model that is still open on all sides without insulation except on the back of the heating plate. The objective of this analysis is to determine the efficiency of this section. Analysis is carried out through numerical and analytical calculations by developing an calculation program based on Matlab. Two analysis conditions are evaluated such as normal condition and accident condition. The result shows that in normal condition, the efficiency of heating section is only 11.34%, and increase to 13,55% in accident conditions. It means that the heat released by the heating plate that is effectively received by cooling water through 5 riser pipes is very small. So, the heating section Mod-1 of RCCS Test Loop has very low efficiency and needs to be improved.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"229 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74732178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical ergonomic evaluation of handwriting performance in left-handed students when using writing armchair 左手学生使用写字椅时书写表现之生物力学与工效学评价
M. Rasyad, E. Muslim
{"title":"Biomechanical ergonomic evaluation of handwriting performance in left-handed students when using writing armchair","authors":"M. Rasyad, E. Muslim","doi":"10.1063/1.5139381","DOIUrl":"https://doi.org/10.1063/1.5139381","url":null,"abstract":"Since ninety percent of the human population in the world are right-handed, many products and facilities are designed for right-handed people. In Indonesia, writing armchair with desktop fixed at the right side is a common product used at tertiary education level, which is uncomfortable for left-handed students because they have to tilt their bodies awkwardly to the right side. Inadequate facilities of left-sided writing armchair in educational institutions are caused by the unknown difference impact on the handwriting performance of left-handed students when using both types of writing armchairs. The purpose of this research is to find out the handwriting performance differences of left-handed students based on biomechanical ergonomic factors. Thirty left-handed university students, aged 18-23 years, participated in this research to conduct 30-minute handwriting experiments using left-sided and right-sided writing armchair. Four measurements parameter used were electromyography (to measure muscle activit...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74452007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of tools utilization monitoring system on labor-intensive manufacturing industries 劳动密集型制造业工具利用监测系统的开发
H. Harja, Tri Prakosa, S. Raharno, Y. Yuwana, I. Nurhadi, Rachmad Hartono, M. Zulfahmi, M.Yanti Pane, M. Yusuf
{"title":"Development of tools utilization monitoring system on labor-intensive manufacturing industries","authors":"H. Harja, Tri Prakosa, S. Raharno, Y. Yuwana, I. Nurhadi, Rachmad Hartono, M. Zulfahmi, M.Yanti Pane, M. Yusuf","doi":"10.1063/1.5138309","DOIUrl":"https://doi.org/10.1063/1.5138309","url":null,"abstract":"Industry 4.0 implementation faces crucial problem when applied in labor-intensive manufacturing industries, which are common industries in Indonesia. The problem is that it requires a well-connected and transparent data among production elements. The purpose of this study was to solve the aforementioned problem by building a cyber-physical workstation system as bridges between the production elements in real world with object models in virtual world. The system acts as a tools monitoring system for obtaining real-time information of actual tools utilization, especially for hand tools which are mostly used in labor-intensive manufacturing industries. The utilization of cyber-physical workstation system model may be the best method for determining the actual utilization of production tool with simple architecture, affordable and minimum negative impact. Workstation monitoring system transforms attendance data tools in the work area and start-finish operation time event into actual tool utilization information. The major contribution of this paper is that the implementation of industry 4.0 on labor-intensive manufacturing industry has become enabled by using cyber- physical workstation system. It was shown that the usage time of each tool on each production operation can be monitored. Furthermore, the estimation of the actual duration of each tool utilization can be calculated. The resulted data will be further utilized as primary data input for building smart tools model.Industry 4.0 implementation faces crucial problem when applied in labor-intensive manufacturing industries, which are common industries in Indonesia. The problem is that it requires a well-connected and transparent data among production elements. The purpose of this study was to solve the aforementioned problem by building a cyber-physical workstation system as bridges between the production elements in real world with object models in virtual world. The system acts as a tools monitoring system for obtaining real-time information of actual tools utilization, especially for hand tools which are mostly used in labor-intensive manufacturing industries. The utilization of cyber-physical workstation system model may be the best method for determining the actual utilization of production tool with simple architecture, affordable and minimum negative impact. Workstation monitoring system transforms attendance data tools in the work area and start-finish operation time event into actual tool utilization informati...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72554224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Numerical simulation of coal particle size (fineness) effect to combustion characteristics of sub-critical pulverized coal boiler 600 MW capacity 煤粒度(细度)对600mw亚临界煤粉锅炉燃烧特性影响的数值模拟
H. Purnomo, B. Sudarmanta
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