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Can network-based testing services have an impact beyond testing for HIV? 以网络为基础的检测服务能产生超越艾滋病毒检测的影响吗?
IF 1.8 4区 医学
Sexual health Pub Date : 2025-04-01 DOI: 10.1071/SH24027
Aliza Monroe-Wise, Magdalena Barr-DiChiara, Antons Mozalevskis, Busisiwe Msimanga, Maeve Brito de Mello, Kafui Senya, Niklas Luhmann, Cheryl Case Johnson, Rachel Baggaley
{"title":"Can network-based testing services have an impact beyond testing for HIV?","authors":"Aliza Monroe-Wise, Magdalena Barr-DiChiara, Antons Mozalevskis, Busisiwe Msimanga, Maeve Brito de Mello, Kafui Senya, Niklas Luhmann, Cheryl Case Johnson, Rachel Baggaley","doi":"10.1071/SH24027","DOIUrl":"https://doi.org/10.1071/SH24027","url":null,"abstract":"<p><p>New strategies and innovations are needed to achieve ambitious global goals for the control of HIV, hepatitis B, hepatitis C and STIs. Network-based testing (NBT) services, including partner services, social network testing, and family and household testing, are a heterogeneous group of practices in which healthcare providers support clients with STIs or bloodborne infections to offer testing and/or other services to sexual or injecting partners, biological children, or household members or contacts. Although significant evidence supports the efficacy of NBT services to identify, diagnose and link to care partners and other contacts of people with HIV, there has been less direct research about NBT for viral hepatitis or STIs, or for providing prevention services to partners. Research is needed to better understand how NBT can best be utilised for multiple infections, specific populations and to achieve maximal impact. Integrating NBT service delivery to achieve testing, treatment and/or prevention for multiple infections may be efficient, and this might include dual or multiplex testing for different populations. Self-testing or self-sampling for partners may overcome barriers to testing. Providing partners who test negative with prevention options, including PrEP or hepatitis B vaccination where appropriate, might be a powerful way to expand prevention efforts for multiple pathogens. NBT is an important tool for identifying those in need of interventions; a better understanding of how to expand and integrate this tool may help achieve cross-cutting health outcomes globally.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing sexual health literacy: a systematic review of measures. 评估性健康素养:对各项措施的系统审查。
IF 1.8 4区 医学
Sexual health Pub Date : 2025-04-01 DOI: 10.1071/SH24042
Tiffany Chenneville, Morgan Haskett, Kaitlyn Ligman, Sarah M Gardy, Camielle Crampsie, Trevor A Hart
{"title":"Assessing sexual health literacy: a systematic review of measures.","authors":"Tiffany Chenneville, Morgan Haskett, Kaitlyn Ligman, Sarah M Gardy, Camielle Crampsie, Trevor A Hart","doi":"10.1071/SH24042","DOIUrl":"https://doi.org/10.1071/SH24042","url":null,"abstract":"<p><p>Sexual health literacy refers to the ability to find, understand, and use information and services to inform decisions and actions related to sexual health. Given the importance of sexual health literacy for improving health outcomes, it is prudent to identify sexual health literacy measures that can be used by healthcare providers, scholars and educators. To address this need, we used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses to conduct a systematic review. This review examined 12 databases to identify existing sexual health literacy self-report scales, subscales or individual items that were available in English, developed for scale validation purposes, and published between 2002, the year the World Health Organization convened experts to provide a clear working definition of sexual health, and 2022. We conducted a risk of bias and quality assurance assessment of the nine articles that met inclusion criteria, and coded articles along the ten components of a sexual health model used as the theoretical framework. Findings revealed mixed quality of identified measures. None of the measures received positive ratings on all eight criteria assessed or addressed all components of the sexual health model. The results from this systematic review suggest the need for a culturally sensitive, valid and reliable scale to assess sexual health literacy that can be used by sexual health professionals to promote sexual health and to reduce deleterious sexual health outcomes.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Service delivery of at-home STI testing using self-collected samples: a qualitative investigation of values and preferences among adults in Rakai, Uganda. 使用自采样本提供在家性传播感染检测的服务:乌干达Rakai成人价值观和偏好的定性调查
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24171
Yasmin P Ogale, M Kathryn Grabowski, Proscovia Nabakka, Herman Mukiibi, Frank Lukabwe, Neema Nakyanjo, Fred Nalugoda, Joseph Kagaayi, Godfrey Kigozi, Charlotte A Gaydos, Julie A Denison, Caitlin E Kennedy
{"title":"Service delivery of at-home STI testing using self-collected samples: a qualitative investigation of values and preferences among adults in Rakai, Uganda.","authors":"Yasmin P Ogale, M Kathryn Grabowski, Proscovia Nabakka, Herman Mukiibi, Frank Lukabwe, Neema Nakyanjo, Fred Nalugoda, Joseph Kagaayi, Godfrey Kigozi, Charlotte A Gaydos, Julie A Denison, Caitlin E Kennedy","doi":"10.1071/SH24171","DOIUrl":"https://doi.org/10.1071/SH24171","url":null,"abstract":"<p><p>Background Studies have shown that clients accept the self-collection of samples for sexually transmitted infection testing (SCS/STI testing), and at-home service delivery is a promising approach to expand diagnosis. However, few studies have examined client values surrounding service delivery in low-resource settings. This formative research study explores clients' service delivery values and preferences for at-home SCS/STI testing in rural Uganda. Methods We conducted semi-structured interviews with 36 adults - 15 males and 21 females - who self-collected a sample for STI testing in Rakai, Uganda, as part of the Rakai Community Cohort Study. After self-collection, participants were asked for their preferences on various at-home service delivery components, including: (1) requesting/receiving testing materials, (2) sending samples to the laboratory, (3) receiving results, and (4) receiving treatment; as well as various service delivery models. We also conducted interviews with nine key informants to contextualize results. Using the framework method, we identified key preferences across all participants, and stratified by gender. Results Participants most valued an at-home SCS/STI testing program that offered timely service, as well as health professionals' expertise. Clients also valued privacy/confidentiality; certainty that processes were completed correctly; access to services/resources; and ownership/responsibility for their own health. Although these values were expressed by both genders, access, privacy/confidentiality and ownership/responsibility were more prominent among females. Conclusions Our findings suggest a potential role for at-home SCS/STI testing in this population, as long as key client values are addressed. Program implementers will need to consider how to balance convenience for clients with professional support.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changing the model of HIV PrEP delivery - nurse-led telehealth in a metropolitan sexual health service: a retrospective analysis. 改变艾滋病毒预防交付模式-护士主导的远程保健在一个大都市性健康服务:回顾性分析。
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24081
Jewel Wai, Arthur Wong, Natalie Ovington, Paul Robinson, Rick Varma
{"title":"Changing the model of HIV PrEP delivery - nurse-led telehealth in a metropolitan sexual health service: a retrospective analysis.","authors":"Jewel Wai, Arthur Wong, Natalie Ovington, Paul Robinson, Rick Varma","doi":"10.1071/SH24081","DOIUrl":"https://doi.org/10.1071/SH24081","url":null,"abstract":"<p><p>Background Innovative models in HIV pre-exposure prophylaxis (PrEP) delivery are required to reduce the burden on clinical services and provide convenience and access for clients. A nurse-led telehealth PrEP clinic ('TelePrEP') with free multi-modal testing pathway has been developed at Sydney Sexual Health Centre (SSHC). Methods Using a multi-model testing pathway, we reviewed retrospective electronic medical record of TelePrEP consultations at SSHC. Primary outcomes were demographic and behavioural characteristics, rates of attendance of TelePrEP appointments and follow-up screening, and rates of PrEP initiation, re-initiation and continuation. Secondary outcomes were length of time from screening to TelePrEP appointment, duration of TelePrEP appointments, adherence to guideline-indicated laboratory testing, and rates of HIV/STI identified through screening. We compared outcomes between the three screening pathways and by Medicare status. Results A total of 472 clients were reviewed. Majority were cis -gender male (99%), non-Medicare (77%), and overseas-born (86%). There was no significant difference in attendance rates between the three screening pathways. The majority of appointments referred through MyCheck (82%) resulted in PrEP continuation; 36% attended follow-up screening, with the highest rates of follow-up referred through a[TEST] (44%), and lowest through Xpress (22%). More non-Medicare clients (38%) attended follow-up screening than Medicare clients (27%). Adherence to national guidelines for testing was high, and screening identified two new HIV diagnoses. Conclusion Nurse-led TelePrEP model is feasible in overcoming issues of accessibility for key population groups including overseas-born MSM. We achieved high overall attendance rates, high adherence to guideline-indicated laboratory monitoring, and rapid linkage to treatment for clients with HIV identified on screening.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A digital citizen science intervention to reduce HIV stigma and promote HIV testing: a randomized clinical trial among adolescents and young adults in Kazakhstan. 数字公民科学干预减少艾滋病毒耻辱和促进艾滋病毒检测:哈萨克斯坦青少年和年轻人的随机临床试验。
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24235
Alissa Davis, Laura Nyblade, Yihang Sun, Olga Balabekova, Sara E Landers, Denis Gryazev, Joseph D Tucker, Valera Gulyaev, Susan L Rosenthal, Karsten Lunze, Weiming Tang, Azamat Kuskulov, Assel Terlikbayeva, Sholpan Primbetova, Mingway Chang, Alfiya Y Denebayeva, Aikerim Utegulovna Akhmetova, Ainur Absemetova, Sholpan Karzhaubayeva, Sairankul Kassymbekova, Marina Maximova, Zhannat Mussina, Gulnar Bekenova, Zhamilya Nugmanova, Zhanna Kalmatayeva, Ludmila Polyakova, Zhanneta Kanaevna Zhazykbaeva, Vitaliy Vinogradov, Amir Shaikezhanov, Meruyert Darisheva, Bella Orynbetova, Elena Norakidze, Mashirov Kozhakhmet, Akbota Tolegenova, Aknur Imadillda, Dariga Satkhozhina, Alikhan Kartamyssov, Zhamilya Kanieva, Albina Aleshina, Olzhas Makhan, Aida Muravyova, Adema Rahimzanova, Arman Duisenbayev, Zhanerke Tursynbek, Nurgazy Dias, Malika Beken, Miras Murzakhan, Zhandos Ali Brown, Daniyal Maitekov, Artur Li, Sandizaira Mergen, Dautali Mergenov, Amirali Kuanysh, Anuar Rakhimbekov, Yenlik Baisbay, Alibek Aruzhan, Zhasmina Kozhambet, Denis Grebenchishikov, Dmitriy Bekker, Sultan Kozhamberdiev, Dauren Salykov, Madina Sagimbayeva, Kamila Yussupova, Gaukhar Mergenova
{"title":"A digital citizen science intervention to reduce HIV stigma and promote HIV testing: a randomized clinical trial among adolescents and young adults in Kazakhstan.","authors":"Alissa Davis, Laura Nyblade, Yihang Sun, Olga Balabekova, Sara E Landers, Denis Gryazev, Joseph D Tucker, Valera Gulyaev, Susan L Rosenthal, Karsten Lunze, Weiming Tang, Azamat Kuskulov, Assel Terlikbayeva, Sholpan Primbetova, Mingway Chang, Alfiya Y Denebayeva, Aikerim Utegulovna Akhmetova, Ainur Absemetova, Sholpan Karzhaubayeva, Sairankul Kassymbekova, Marina Maximova, Zhannat Mussina, Gulnar Bekenova, Zhamilya Nugmanova, Zhanna Kalmatayeva, Ludmila Polyakova, Zhanneta Kanaevna Zhazykbaeva, Vitaliy Vinogradov, Amir Shaikezhanov, Meruyert Darisheva, Bella Orynbetova, Elena Norakidze, Mashirov Kozhakhmet, Akbota Tolegenova, Aknur Imadillda, Dariga Satkhozhina, Alikhan Kartamyssov, Zhamilya Kanieva, Albina Aleshina, Olzhas Makhan, Aida Muravyova, Adema Rahimzanova, Arman Duisenbayev, Zhanerke Tursynbek, Nurgazy Dias, Malika Beken, Miras Murzakhan, Zhandos Ali Brown, Daniyal Maitekov, Artur Li, Sandizaira Mergen, Dautali Mergenov, Amirali Kuanysh, Anuar Rakhimbekov, Yenlik Baisbay, Alibek Aruzhan, Zhasmina Kozhambet, Denis Grebenchishikov, Dmitriy Bekker, Sultan Kozhamberdiev, Dauren Salykov, Madina Sagimbayeva, Kamila Yussupova, Gaukhar Mergenova","doi":"10.1071/SH24235","DOIUrl":"https://doi.org/10.1071/SH24235","url":null,"abstract":"<p><p>Background Kazakhstan has a high HIV incidence among adolescents and young adults (AYA), and high HIV stigma contributing to low HIV testing uptake. We examined whether an AYA-developed digital crowdsourced intervention reduced HIV stigma compared with conventional public health materials among AYA in Almaty, Kazakhstan. Methods A total of 216 AYA (females:116/males:110) aged 16-24 years were recruited to the online study cohort and randomized 1:1 to the intervention or control arm. AYA were exposed to the crowdsourced intervention or control materials once a week for 5weeks, with equivalent exposures between arms. Outcomes included a total HIV stigma score assessed at baseline, immediately post-intervention and 2months post-intervention from January to August 2023. We conducted multilevel mixed models to compare changes over time by arm and sex. Results AYA in the intervention arm had significantly lower HIV testing stigma 2months post-intervention (adjusted mean change (AMC): -0.73 (-1.07, -0.39)) than AYA in the control arm (AMC: -0.06 (-0.42, 0.30); P =0.032). Female AYA in the intervention arm had significantly lower total HIV stigma immediately post-intervention (AMC: -4.91 (-7.25, -2.58)) and 2months post-intervention (AMC: -5.16 (-7.48, -2.84)) than females in the control arm (immediately post-intervention AMC: -0.03 (-2.63, 2.57) and 2-months post-intervention AMC: -0.07 (-2.70, 2.56); P =0.012, P =0.012). Conclusions The AYA-developed crowdsourced intervention decreased HIV testing stigma, although this effect was moderated by sex, and decreased total HIV stigma among female AYA. Crowdsourced interventions may be a promising way to engage communities to develop interventions to decrease HIV stigma.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring sexual desire and fantasies: a cross-sectional online study on gender differences on Iranian adults. 探索性欲望与性幻想:伊朗成人性别差异的横断面线上研究。
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24179
Rezvan Shekarchi, Filippo Maria Nimbi
{"title":"Exploring sexual desire and fantasies: a cross-sectional online study on gender differences on Iranian adults.","authors":"Rezvan Shekarchi, Filippo Maria Nimbi","doi":"10.1071/SH24179","DOIUrl":"https://doi.org/10.1071/SH24179","url":null,"abstract":"<p><p>Background Sexual fantasies represent a cognitive pattern that influences sexual activation and desire. This study aims to investigate the relationship between sexual fantasies, sexual desire and overall sexual functioning among Iranian adults. Methods A total of 1353 volunteers from the general population participated by filling out questionnaires including, the Sexual Desire and Erotic Fantasies Questionnaire, the International Index of Erectile Function and the Female Sexual Function Index. Sexual fantasies were categorized based on predefined criteria. Statistical analyses were conducted using correlation and regression techniques to explore these relationships. Results Men reported more explicit sexual fantasies, including active roles, common sexual behaviours and dominance, during sexual activities (mean1.62, s.d.1.16), taboo elements (e.g. sex with minors, animals, family members and rape; mean0.38, s.d.0.60) and fantasies with diverse partners (mean5.18, s.d.4.16). In contrast, women preferred romantic content (mean1.97, s.d.0.97) and a passive role. No gender differences were observed in bondage, dominance, sadism and masochism fantasies. Both genders showed a strong correlation between sexual fantasies and sexual desire (Men0.461, Women0.372). Conclusion Understanding these patterns in a conservative country, such as Iran, may contribute to culturally sensitive intervention in traditional culture. For instance, in sex therapy or workshops for couples on utilizing fantasy to enhance sexual satisfaction, subject to the values of modesty and privacy. This research reveals valuable insight into sexual imagery and sexual performance, and fills a gap in cultural studies. However, further research is needed to validate these findings.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving engagement with sexual and reproductive health services among young African migrants in Australia. 改善在澳大利亚的非洲青年移民对性健康和生殖健康服务的参与。
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24186
Humaira Maheen, Negin Mirzaei Damabi, Zohra S Lassi
{"title":"Improving engagement with sexual and reproductive health services among young African migrants in Australia.","authors":"Humaira Maheen, Negin Mirzaei Damabi, Zohra S Lassi","doi":"10.1071/SH24186","DOIUrl":"https://doi.org/10.1071/SH24186","url":null,"abstract":"<p><p>Background Sexual and reproductive health (SRH) services are underutilised by young people from migrant and refugee backgrounds in many Western countries, including Australia. Young African migrants, a growing demographic in Australia, face unique challenges, including stigma associated with seeking sexual health care and limited sexual health literacy, which lead to adverse SRH outcomes. The study aims to (1) develop an understanding of young African migrants' knowledge of existing sexual health services in Australia and (2) explore young people's perceptions of youth-friendly SRH services for optimal engagement by young migrants from African backgrounds. Methods A qualitative study was conducted in Melbourne, Australia, in 2019, using three participatory workshops involving 30 young African migrants aged 18-24 years. The data was analysed thematically. Results Thematic analysis identified three key themes: (1) lack of visibility and information of existing sexual health services affects service use, (2) cultural stigma associated with sexual health affects help-seeking and health service engagement, and (3) key attributes of youth-friendly SRH care for young African migrants. None of the participants were aware of sexual health services in Australia. Although general practitioners were the most commonly known healthcare providers, many participants avoided seeking SRH care from them due to concerns about confidentiality. Participants emphasised the importance of accessible, youth-friendly SRH services, recommending culturally informed approaches and highlighting preferences for provider characteristics, such as younger age, strong confidentiality assurances, and gender-specific options in provider selection. Conclusion The lack of awareness about sexual health services among young African migrants hinders their ability to access appropriate care. Efforts to promote SRH services should include targeted, culturally sensitive outreach and clear communication to address misconceptions and barriers. Adopting a cultural lens in designing youth-friendly SRH services may enhance their utilisation and improve SRH outcomes among this population.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV pre-exposure prophylaxis re-initiation among men who have sex with men: a multi-center cohort study in China. 中国男男性行为者HIV暴露前预防再启动:一项多中心队列研究
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24200
Yifan Dai, Zhuoheng Yin, Chunyan Li, Chengxin Fan, Heping Zhao, Haojie Huang, Quanmin Li, Songjie Wu, Aniruddha Hazra, Jonathan Lio, Ke Liang, Linghua Li, Renslow Sherer, Joseph D Tucker, Cheng Wang, Weiming Tang
{"title":"HIV pre-exposure prophylaxis re-initiation among men who have sex with men: a multi-center cohort study in China.","authors":"Yifan Dai, Zhuoheng Yin, Chunyan Li, Chengxin Fan, Heping Zhao, Haojie Huang, Quanmin Li, Songjie Wu, Aniruddha Hazra, Jonathan Lio, Ke Liang, Linghua Li, Renslow Sherer, Joseph D Tucker, Cheng Wang, Weiming Tang","doi":"10.1071/SH24200","DOIUrl":"https://doi.org/10.1071/SH24200","url":null,"abstract":"<p><p>Background Data on persistent use of HIV pre-exposure prophylaxis (PrEP) is limited among Chinese men who have sex with men (MSM). This study aimed to explore factors associated with the re-initiation of PrEP among Chinese MSM from a longitudinal PrEP demonstration trial. Methods A multi-center cohort study was conducted in Guangzhou and Wuhan, China (September 2021-2024), providing 1134 MSM participants with a 12-month dosage of tenofovir disoproxil fumarate and emtricitabine (TDF/FTC) as oral PrEP. Following the trial, a subgroup of participants were invited to complete a 3-month post-trial follow-up survey. These participants were categorized on the basis of self-reported PrEP use patterns into (1) continued PrEP use, (2) discontinued without re-initiation, and (3) re-initiated after discontinuation. Log-binomial regression models were used to assess factors associated with PrEP re-initiation. Results Out of 408 participants who completed the 3-month post-trial follow-up survey, 70.1% (n =286/408) reported discontinuing PrEP, and 50.7% (n =145/286) of those who discontinued subsequently re-initiated PrEP. Participants who had concurrent sexual partnerships (adjusted risk ratio [aRR]=1.47, 95% CI: 1.11-1.96), used drugs during sex (aRR=1.34, 95% CI: 1.09-1.65), or lived alone (aRR=1.29, 95% CI: 1.03-1.61) were more likely to re-initiate PrEP. The Likert scale analysis indicated that perceived partner influence, specifically the expectation of condomless sex, played a significant role in re-initiation decisions (P =0.03). Conclusion Individuals engaging in higher-risk behaviors are more likely to re-initiate PrEP, highlighting the dynamic nature of risk perception. Future interventions should focus on promoting both re-initiation and consistent condom use, emphasizing partner-related dynamics and substance use as key factors in PrEP decisions among MSM.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing and projecting the global impacts of female infertility: a 1990-2040 analysis from the Global Burden of Disease study. 评估和预测女性不育的全球影响:来自全球疾病负担研究的1990-2040年分析。
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24237
Hanjin Wang, Bengui Jiang
{"title":"Assessing and projecting the global impacts of female infertility: a 1990-2040 analysis from the Global Burden of Disease study.","authors":"Hanjin Wang, Bengui Jiang","doi":"10.1071/SH24237","DOIUrl":"https://doi.org/10.1071/SH24237","url":null,"abstract":"<p><p>Background This study aims to assess the global burden of female infertility from 1990 to 2040. Methods Data on disability-adjusted life years associated with female infertility were sourced from the Global Burden of Disease 2021 study. Generalized additive models were utilized to predict trends for the period spanning from 2022 to 2040. Results The global burden of female infertility is expected to increase significantly, with the age-standardized disability-adjusted life year rate projected to reach 19.92 (95% uncertainty interval (UI): 18.52, 21.33) by 2040. The projected estimated annual percentage change (EAPC) for the age-standardized disability-adjusted life year rate from 2022 to 2040 is expected to be 1.42, with a 95% confidence interval (CI) of 1.3951-1.4418. This is in contrast to the EAPC of 0.71 (95% CI: 0.5391-0.8789) observed from 1990 to 2021. Central sub-Saharan Africa is projected to have the highest age-standardized rate at 29.37 (95% UI: 24.58-34.16), whereas Australasia is expected to have the lowest at 0.78 (95% UI: 0.72-0.84). Age-specific projections show a consistent decline in infertility rates across all age groups. Countries such as Kenya, Chad and Peru exhibit EAPCs exceeding 9.00, whereas Mali and South Africa show significant negative EAPCs. Correlation analysis indicates that regions with a higher sociodemographic index generally have lower female infertility burdens, with notable trends observed in Europe and Asia. Conclusion The projected global burden of female infertility is expected to increase significantly from 2021 to 2040, with notable regional disparities. Central sub-Saharan Africa and south Asia are anticipated to experience higher burdens, whereas overall rates are projected to decrease across different age groups.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological trends of chlamydia, gonorrhoea, trichomoniasis, genital herpes and syphilis in India from 1990 to 2019: analysis from the Global Burden of Disease study (GBD 2019). 1990年至2019年印度衣原体、淋病、滴虫病、生殖器疱疹和梅毒的流行病学趋势:来自全球疾病负担研究(GBD 2019)的分析
IF 1.8 4区 医学
Sexual health Pub Date : 2025-03-01 DOI: 10.1071/SH24185
Ashu Kumari, Kumari Akanksha, Omprokash Dutta, Farah Deeba, Nasir Salam
{"title":"Epidemiological trends of chlamydia, gonorrhoea, trichomoniasis, genital herpes and syphilis in India from 1990 to 2019: analysis from the Global Burden of Disease study (GBD 2019).","authors":"Ashu Kumari, Kumari Akanksha, Omprokash Dutta, Farah Deeba, Nasir Salam","doi":"10.1071/SH24185","DOIUrl":"https://doi.org/10.1071/SH24185","url":null,"abstract":"<p><p>Background Sexually transmitted infections (STIs) other than HIV are a major public health concern globally. The goal of this study is to analyse the trends of the five most common STIs; chlamydia, gonococcal infection, trichomoniasis, genital herpes and syphilis in India and its states from 1990 to 2019. Methods We extracted data pertaining to STIs from the Global Burden of Disease study, 2019 (GBD 2019), and analysed the burden of disease based on individual STI, for both sexes, across multiple age groups, and for each state and union territory of India. Results Incidence of STIs increased by 82.79% from 54.64million in 1990 to 99.88million in 2019, and disability-adjusted life years decreased by 48.66% from 1.51million to 0.77million, which is primarily attributed to a decline in disability-adjusted life years for syphilis. The incidence was higher in men compared to women. The incidence rate for chlamydia, trichomoniasis and genital herpes increased, the incidence rate for syphilis declined, whereas the incidence rate for gonococcal infection did not show any substantial change. Most of the disability-adjusted life years and deaths in 2019 were contributed by syphilis. Conclusion The burden of STIs in India is substantial and calls for comprehensive efforts to stem the tide of increasing incidence of STIs. Enhancing surveillance, increasing awareness and targeted control programs are recommended for the affected populations.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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