Sexual health最新文献

{"title":"HPV awareness and anal cancer prevention among sexual minority men living with HIV in Nigeria: insights from an affirming clinical setting.","authors":"Connor R Volpi, John Chama, Ruxton Adebiyi, Jumoke A Aigoro, Yerima Jibrin Bawa, Kazeem E Kolawole, Uchenna Ononaku, Naomi Ayuba, Ashley Shutt, Abayomi Aka, Stephen E Goldstone, Patrick Dakum, Joel M Palefsky, Sylvia Adebajo, Karin E Tobin, Rebecca G Nowak","doi":"10.1071/SH25193","DOIUrl":"10.1071/SH25193","url":null,"abstract":"<p><strong>Background: </strong>Sexual minority men (SMM) living with HIV face an elevated risk of anal cancer, and SMM-affirming HIV clinics serve as vital entry points for cancer prevention. We evaluated human papillomavirus (HPV) knowledge, vaccine acceptability and whether time living with HIV was associated with anal cancer symptom awareness.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted at an HIV clinic offering anal cancer prevention in Abuja, Nigeria. Descriptive statistics were used to summarize HPV knowledge and vaccine acceptability. Multivariable negative binomial regression evaluated the number of anal cancer symptoms correctly reported using adjusted prevalence ratios (aPR) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Among 249 SMM living with HIV, 20.5% reported having heard of HPV. Fewer than 20% correctly identified key anal cancer symptoms, including anal bleeding (15.7%) and a lump or mass in the anus (16.9%). Time living with HIV was initially associated with anal cancer symptom awareness, but not after adjustment (aPR 1.02, 95% CI 0.98-1.07). Other independent predictors of anal cancer symptom awareness were anal cancer screening (aPR 1.51, 95% CI 1.15-1.97) and knowing HPV vaccine can prevent anal cancer (aPR 1.52, 95% CI 1.18-1.98). Despite low HPV awareness, 93.6% of participants reported willingness to receive HPV vaccine.</p><p><strong>Conclusion: </strong>Integrating cancer prevention services into SMM-affirming HIV care may offer an opportunity to strengthen HPV-related knowledge and reduce cancer disparities.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"23 2","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13052982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual and gender minority stigma, and associations with perceived barriers to HIV testing and HIV testing behaviors among adolescents and young adults in Kazakhstan.","authors":"Hao Wen, Yihang Sun, Sara Landers, Gaukhar Mergenova, Olga Balabekova, Denis Gryazev, Alissa Davis","doi":"10.1071/SH25099","DOIUrl":"10.1071/SH25099","url":null,"abstract":"<p><strong>Background: </strong>Kazakhstan is experiencing a rising HIV epidemic, with adolescents and young adults (AYA) accounting for nearly one-quarter of new infections. However, HIV testing rates remain low, partly due to stigma, especially sexual and gender minority (SGM) stigma.</p><p><strong>Methods: </strong>We examined the prevalence and associations between SGM stigma, perceived barriers to HIV testing, and testing behaviors among 216 AYA in Almaty, Kazakhstan. The analysis used baseline survey data from enrolled RCT participants.</p><p><strong>Results: </strong>Results showed that male and heterosexual AYA reported significantly higher SGM stigma than female or SGM AYA. Regression analyses found that higher SGM stigma was associated with greater perceived barriers to HIV testing (β = 0.72, P < 0.001), but not with HIV testing uptake.</p><p><strong>Conclusions: </strong>These findings suggest that SGM stigma contributes to perceived barriers that discourage HIV testing. Given that current HIV stigma interventions may not adequately address gendered or sexual identity-related stigma, targeted strategies that address the intersection of SGM and HIV stigma among AYA, especially among males, are timely needed.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13091682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing machine learning-based identification of sexual health influencers for HIV self-testing distribution among men who have sex with men in China: a secondary analysis of a quasi-experimental trial.","authors":"Qian Zou, Yi Zhou, Ye Zhang, Dan Wu, Xinyuan Zhang, Fengshi Jing, Jie Fan, Xi He, Joseph D Tucker, Weiming Tang","doi":"10.1071/SH25214","DOIUrl":"10.1071/SH25214","url":null,"abstract":"<p><strong>Background: </strong>Secondary distribution of HIV self-testing can expand testing among men who have sex with men. A parent quasi-experimental trial found that sexual health influencers (SHIs) identified by a machine-learning model achieved greater peer uptake than those identified by an empirical scale, but the factors driving distribution effectiveness remain unclear.</p><p><strong>Methods: </strong>We conducted a secondary analysis of the parent trial (ChiCTR2000039632) in five provinces in southern China. Participants were randomized to either the empirical scale or machine-learning identification arm, and SHIs were then selected within each arm. The current analysis included 196 SHIs with complete follow up. Effective distribution was defined as motivating at least one peer to test. Predictor variables captured sociodemographic, behavioral and network characteristics. Multivariable Poisson LASSO models with multiple imputation and cross-validation estimated adjusted incidence rate ratios (aIRRs).</p><p><strong>Results: </strong>Among 196 SHIs (mean age 28 years), 46.9% achieved effective distribution. A total of 286 unique peers returned verified HIV self-testing results, of whom 118 (41.3%) were first-time testers. Peer HIV testing was associated with stronger awareness of peers' HIV status (aIRR 1.31; 95% CI 1.16-1.48) and more active sharing of HIV information (aIRR 1.28; 95% CI 1.10-1.50). SHIs who had been accompanied during their own HIV test recruited more newly tested peers (aIRR 1.94; 95% CI 1.12-3.37).</p><p><strong>Conclusions: </strong>Our data have implications for secondary distribution of HIV self-test kits and suggest the need for capacity strengthening related to peer engagement in HIV self-testing.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing STI testing and diagnosis disparities between Asian people with HIV and other racial/ethnic subpopulations in Washington, District of Columbia: a longitudinal analysis of the DC Cohort, 2018-2023.","authors":"Jenny Yeon Hee Kim, Lauren F O'Connor, Yun Seong Ji, Morgan Byrne, Michael A Horberg, Amanda D Castel, Anne K Monroe","doi":"10.1071/SH25144","DOIUrl":"10.1071/SH25144","url":null,"abstract":"<p><strong>Background: </strong>People of Asian ethnicity represent one of the fastest-growing populations in the United States and may experience unique social and cultural challenges to accessing sexual healthcare. This analysis explores disparities in annual sexually transmitted infection screening and diagnosis rates per person-year between Asian and non-Asian people with human immunodeficiency virus in Washington, District of Columbia (DC).</p><p><strong>Methods: </strong>Using District Columbia cohort data, a longitudinal study of people living with human immunodeficiency virus receiving care in Washington, DC, we analyzed people with human immunodeficiency virus aged 18 or older with at least 1 year of follow-up between 2018 and 2023. Logistic regression was used to examine differences in sexually transmitted infection screening and diagnoses between Asian and non-Asian participants, while linear trend analyses were used to assess changes in the number of screenings and diagnoses between Asian and non-Asian participants.</p><p><strong>Results: </strong>Among 8679 eligible participants, 0.88% (n = 76) were Asian. No significant differences in total sexually transmitted infection screenings or diagnoses were observed. However, Asian participants had higher screening rates per person-year for pharyngeal and urogenital gonorrhea, pharyngeal chlamydia, and syphilis. Chlamydia incidence was higher among Asian than non-Asian participants. Over 30% of both groups met the annual screening recommendation during the study period.</p><p><strong>Conclusions: </strong>Asians had comparable screening rates to non-Asians, but the small sample size limited the generalizability of our findings. Nonetheless, this study helps address an existing gap in the literature on Asian sexual health. Larger studies with detailed ethnic and social data are needed to deepen our understanding of sexual health service use within Asian communities.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The HIV response at Resilience During an Inflection Point: Resilience, Innovation and Equity.","authors":"Joseph Tucker, Amy Mullens, Chelsea Morroni, Jason Ong","doi":"10.1071/SH25236","DOIUrl":"https://doi.org/10.1071/SH25236","url":null,"abstract":"<p><p>World AIDS Day 2025 arrives at a critical inflection point for the global HIV response. Four decades of scientific progress have transformed HIV into a manageable chronic condition, yet funding contractions, widening inequities, and persistent stigma threaten progress towards epidemic control. This review of the Special Collection highlights emerging challenges and opportunities across prevention, care, and social contexts, with a focus on resilience. Digital innovation, accelerated by COVID-19, is reshaping HIV service delivery through telehealth, remote engagement, and online research platforms. Studies of PrEP use across the Asia-Pacific region reveal cyclical patterns of prevention, varying preferences for long-acting and oral formulations, and the centrality of person-centred approaches. Other papers examine sexual satisfaction among people living with HIV, showing the ongoing influence of stigma even in the era of U=U (Undetectable equals untransmittable). Several contributions highlight enduring social and gendered inequities, including stigma among healthcare workers and gaps in menopause, reproductive health, and psychosocial care for women living with HIV. Evidence from humanitarian settings demonstrates how climate-related crises heighten HIV vulnerabilities, while peer-led navigation models illustrate community resilience. These papers underscore the need to integrate scientific innovation with equity, community leadership, and sustained solidarity as the global HIV movement adapts to a rapidly changing landscape.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV self-testing secondary distribution among index with different HIV status in China: a pooled analysis of three trials.","authors":"Siyue Hu, Yi Zhou, Fengshi Jing, Xinyuan Zhang, Wei Ai, Hang Lyu, Xi He, Jie Fan, Dan Wu, Weiming Tang","doi":"10.1071/SH25127","DOIUrl":"10.1071/SH25127","url":null,"abstract":"<p><strong>Background: </strong>Secondary distribution of HIV self-testing (HIVST) may improve HIV testing coverage and facilitate the diagnosis of people living with HIV, but whether this effect is similar among index men who have sex with men (MSM) with different HIV status is still not clear.</p><p><strong>Methods: </strong>This study is a pooled analysis of three trials (ChiCTR1900025433, ChiCTR2000039632 and ChiCTR2200064517) conducted by our study team. These three trials aimed to evaluate the effectiveness of monetary incentives in promoting the secondary distribution of HIVST in China. MSM who participated in the three trials were grouped into four groups based on their HIV and intervention status. The control group followed a standard HIVST distribution process in which participants (defined as 'index') distributed the HIVST kits to members of their social network (defined as 'alter'), whereas the intervention group received monetary incentives for promoting altered testing.</p><p><strong>Results: </strong>Between June 2018 and December 2023, 891 unique MSM from 68 cities in China were recruited as index participants, with 55, 54, 390 and 392 categorized into the positive control, positive intervention, negative control and negative intervention groups, respectively. A total of 1035 alters tested for HIV, including 962 motivated by 782 HIV-negative index participants and 73 motivated by 109 index participants living with HIV. The negative intervention group motivated significantly more unique alters to test than the negative control group (IRR 2.46, 95% CI: 1.85, 3.28). With intervention, index living with HIV was less likely to motivate alters for HIV testing (IRR 0.36, 95% CI: 0.23, 0.57). An interaction was not detected between intervention and HIV status. The proportion of newly tested testers among alters was 52%, 48%, 38% and 40% in the positive control, positive intervention, negative control and negative intervention groups, respectively. A total of 41 alters were diagnosed with HIV (5 motivated by index participants living with HIV).</p><p><strong>Conclusions: </strong>The effect of monetary incentive was lower among MSM living with HIV, even though they tend to identify alters with HIV-reactive results. Integrating incentive-based HIVST secondary distribution into routine HIV prevention and care services is recommended.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between sexual orientation-related stigma and sleep quality in gay men: a moderated mediation model.","authors":"Bukuan Sun, Jiaxiao Jiang, Guanghui Nie, Binfeng Zhang, Lu Wang, Peixuan Tan, Gaomei Luo, Xiuxia Li","doi":"10.1071/SH24249","DOIUrl":"10.1071/SH24249","url":null,"abstract":"<p><strong>Background: </strong>This study aims to explore the relationship between sexual orientation-related stigma and sleep quality in gay men, the mediating roles of depression and perceived social support in this relationship, and the moderating mediation effects of living alone and being only children.</p><p><strong>Methods: </strong>Between April and August 2022, 528 gay men were recruited. All participants completed the Sexual Orientation-related Stigma Scale, the Chinese version of the Patient Health Questionnaire, the Multidimensional Survey of Perceived Social Support and the Pittsburgh Sleep Quality Index. Structural equation models were constructed for mediation and moderated mediation analysis.</p><p><strong>Results: </strong>Sexual orientation-related stigma significantly impacts the sleep quality of gay men, with depression and social support playing a chain-mediated role in this relationship. Being an only child moderates the relationship between sexual orientation-related stigma and social support, whereas living alone moderates the relationship between sexual orientation-related stigma and depression.</p><p><strong>Conclusions: </strong>The results emphasize the importance of sexual orientation-related stigma in the mental health and sleep quality of gay men. Reducing stigma, increasing social support, and considering individual differences related to family structure and living arrangements are all crucial for enhancing the mental health and sleep quality of gay men. Future research should delve deeper into these complex relationships to develop more effective interventions; thus, improving the overall quality of life and happiness of gay men.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145640186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual health survey recruitment approaches among patients in community health centers.","authors":"Debjyoti Datta, Eli Andrade, Bryant N Gomez, Sarit A Golub, Robert Beil, Viraj V Patel","doi":"10.1071/SH24168","DOIUrl":"10.1071/SH24168","url":null,"abstract":"<p><strong>Background: </strong>Black and Latino communities are disproportionately affected by HIV, and are often underrepresented in sexual health research. It is crucial to understand their participation in research, and gauge the impact of non-response bias in reported results. A sequential multimodal approach to recruitment could potentially increase the response rates and representativeness of the sample by increasing the likelihood of response from the participants. However, data on the use of various recruitment approaches (i.e. low-barrier strategies) for engaging patients from urban Federally Qualified Health Centers in sexual health research are limited.</p><p><strong>Methods: </strong>We analyzed survey recruitment data among patients prescribed PrEP at Federally Qualified Health Centers serving largely black and Latino/a communities to understand the impact of virtual recruitment. We used four sequential attempts over 6 months to recruit participants for an incentivized patient feedback survey on sexual health and PrEP services. We also examined demographic differences, including age, sexual identity, gender identity and race/ethnicity, between responders and non-responders.</p><p><strong>Results: </strong>We recruited participants from January to June 2022. The overall response rate was 20.8% (54/259). There was an incremental increase in responses based on the number of strategies used: 66.7% (36/54) of participants were recruited by using one strategy (email only), 22.2% (12/54) were recruited by using two strategies (email and phone calls) and 11.1% (6/54) were recruited using three (email, phone calls and SMS) or four strategies (email, phone calls, SMS and an additional phone call). Responders had received a more recent PrEP prescription compared with non-responders; mean ± s.d. months between the most recent PrEP prescription and the first recruitment attempt date of the study was 15 ± 17 months for responders and 27 ± 24 months for non-responders. We observed no other significant differences in demographic characteristics between responders and non-responders.</p><p><strong>Conclusion: </strong>Response rates to an online sexual health survey among urban Federally Qualified Health Center patients were low using sequential multimodal virtual recruitment approaches, particularly among those without recent healthcare engagement. There were no demographic differences between responders and non-responders. Findings highlight the need for alternative innovative methods for research engagement and to reduce potential bias.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12914554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145373058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparing for next-generation PrEP: awareness and willingness to use long-acting injectable cabotegravir among men who have sex with men and trans women across Asia.","authors":"Heather-Marie A Schmidt, Curtis Chan, Polin Ung, Tiara Nisa, Jason J Ong, Warittha Tieosapjaroen, Kimberly E Green, Nittaya Phanuphak, Michael M Cassell, Nicky Suwandi, Hua Boonyapisomparn, Midnight Poonkasetwattana, Lei Zhang, Benjamin R Bavinton","doi":"10.1071/SH25065","DOIUrl":"10.1071/SH25065","url":null,"abstract":"<p><strong>Background: </strong>Pre-exposure prophylaxis (PrEP) use could be accelerated by offering alternatives that overcome key barriers associated with oral PrEP. This study aimed to understand willingness and preferences for long-acting injectable cabotegravir (CAB-LA) among gay men and other men who have sex with men (MSM), and transgender women (TGW) in Asia.</p><p><strong>Methods: </strong>An online cross-sectional survey was conducted from May to November 2022 among HIV-negative or unknown status MSM and TGW aged ≥18 years across 15 and 11 Asian countries/territories, respectively. Survey items included awareness and use of PrEP and CAB-LA, willingness to use current and emerging PrEP options, and attitudes towards CAB-LA. Descriptive statistics and logistic regression were used to analyse associations with willingness to use CAB-LA.</p><p><strong>Results: </strong>Among 11,870 MSM and 980 TGW, 21.4% (n = 2448) and 32.5% (n = 295) were aware of CAB-LA, respectively, and 17.2% (n = 2036) and 16.8% (n = 165) were willing to use it. CAB-LA was the most preferred PrEP option for 3.6% (n = 400) of MSM and 6.5% (n = 61) of TGW. Awareness and willingness varied across countries/territories and populations. Key benefits of CAB-LA included HIV protection (57.8% MSM, 46.8% TGW), no need for daily pills (42.6% MSM, 31.1% TGW) and longer-term protection (38.0% MSM, 23.6% TGW). Main concerns included cost (39.6% MSM, 22.1% TGW), side-effects (37.5% MSM, 22.2% TGW), insufficient knowledge (33.3% MSM, 20.6% TGW) and pain (21.4% MSM, 24.9% TGW).</p><p><strong>Conclusions: </strong>Successful introduction of CAB-LA, or other new long-acting injectable PrEP options, in Asia will require strategies to raise awareness and demand-generation that responds to the perceived benefits and concerns of communities.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145401966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between young people's internet pornography use and psychosexual well-being: a systematic review.","authors":"Yishu Li, Roger Ingham, Heather Armstrong","doi":"10.1071/SH25118","DOIUrl":"10.1071/SH25118","url":null,"abstract":"<p><p>The internet has greatly increased the ease of access to pornography and the privacy of its use, accompanied by a notable rise in consumption among young people. This review aimed to systematically review and narratively synthesise quantitative evidence on the prevalence, motivations, and content types of internet pornography use - as well as its associations with multiple domains of psychosexual well-being, including attitudes and emotions towards use, sexual self-concept, sexual desire and functioning, and compulsive use - among individuals aged 16-25 years. Following a pre-registered protocol, we originally conducted a systematic search of PubMed, PsycINFO, and Web of Science on 20 May 2024 and updated on 24 April 2025 for studies published from 1 January 2000 to 24 April 2025 that reported associations. Study quality was assessed. Twenty-seven studies (30,023 participants) were included in the systematic review. Measurement details were reported for the pornography use variables and the psychosexual well-being variables. The results indicate that most young people have used internet pornography, with a higher prevalence reported in men than women. Additionally, gender differences related to internet pornography were found in reported motivation and content types, attitudes and emotions, sexual self-concept, sexual desire and functioning, and compulsive use.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}