Surgical Innovation最新文献_第3页

The Potential of NE'X GLUE as an Effective Solution for Air Leak Prevention in Minimally Invasive Thoracic Procedures. NE'X胶在微创胸椎手术中预防漏气的潜力。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-09-17 DOI: 10.1177/15533506261488621

Diego Gonzalez-Rivas, Bojan Gulic, Dherar Alshehab, Essa Alghunaim, Javier Gallego, Yousef Aleid

{"title":"The Potential of NE'X GLUE as an Effective Solution for Air Leak Prevention in Minimally Invasive Thoracic Procedures.","authors":"Diego Gonzalez-Rivas, Bojan Gulic, Dherar Alshehab, Essa Alghunaim, Javier Gallego, Yousef Aleid","doi":"10.1177/15533506261488621","DOIUrl":"https://doi.org/10.1177/15533506261488621","url":null,"abstract":"BackgroundPostoperative air leaks remain a clinically relevant complication after minimally invasive pulmonary tissue resections, often prolonging drainage, hospitalisation, and recovery. Surgical sealants may improve intraoperative airtight closure and reduce postoperative burden.ObjectiveEvaluate the clinical efficacy of NE'X GLUE, an albumin-based, biocompatible, two-component surgical adhesive, for preventing air leaks after minimally invasive pulmonary tissue resections.MethodsA prospective study group included 28 patients who underwent atypical resections, segmentectomies, or lobectomies with NE'X GLUE applied using the three-layer \"sandwich\" technique. Outcomes were compared with a retrospective control group of 22 patients who underwent similar procedures without sealant. Postoperative air leaks, drainage duration, re-drainage, hospitalisation, complications, emergency consultations, reinterventions, and pneumothorax recurrence were assessed.ResultsPostoperative air leaks occurred in 4 patients in the NE'X GLUE group (14.3%), all resolving within 24 hours without additional intervention, compared with 40.9% in the control group. Mean air-leak duration was 0.5 days versus 2.8 days. Re-drainage was not required after sealant use, whereas it was performed in 13.6% of controls. Drainage removal within 2 days was achieved in 85.7% versus 31.8% of patients. Mean hospitalisation was 3.9 versus 6.8 days. Grade I-IV complications occurred in 3.6% versus 36.4%, and emergency consultations in 3.6% versus 22.7%. No reinterventions or pneumothorax recurrences occurred in the NE'X GLUE group.ConclusionNE'X GLUE applied with the \"sandwich\" technique was associated with fewer postoperative air leaks, earlier drainage removal, shorter hospitalisation, and fewer complications after minimally invasive pulmonary tissue resections.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261488621"},"PeriodicalIF":2.2,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Instrument Detection and Tracking in Orthopaedic Surgery Using Computer Vision. 基于计算机视觉的骨科手术器械检测与跟踪。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-09-15 DOI: 10.1177/15533506261489510

Melissa Paraskevaidis, David Alexander Back, Elian Niklas Oudintsov, Ulrich Stöckle, Tobias Gehlen

{"title":"Surgical Instrument Detection and Tracking in Orthopaedic Surgery Using Computer Vision.","authors":"Melissa Paraskevaidis, David Alexander Back, Elian Niklas Oudintsov, Ulrich Stöckle, Tobias Gehlen","doi":"10.1177/15533506261489510","DOIUrl":"https://doi.org/10.1177/15533506261489510","url":null,"abstract":"The purpose of this study is to establish a methodology to digitalise instrument and object tracking analysis in orthopaedic surgery and generate insights into surgical procedures using spatiotemporal data, without introducing costly equipment into the operating theatre. This approach aims to produce descriptive statistics that demonstrate potential improvements in surgical safety and efficiency, presenting opportunities for further research and application in orthopaedic surgery.MethodsThe proposed method utilises a computer vision-based approach by applying instrument tracking and object detection software on a video of a surgical procedure. The model was trained on 23,398 images representing 14 surgical instruments. The model achieved a mean Average Precision of 95.9% on the validation and 96.2% on the test set. A feasibility test was conducted using a surgical video (275 frames, 11 seconds) to detect and track surgical tools. Movement metrics such as distance and spatial distribution were computed to quantify instrument motion patterns.ResultsAll instruments were successfully detected and tracked. Retractors showed lowest (mean total movement <50 px), while Metzenbaum scissors demonstrated the highest activity (>150 px). Violin plots revealed variation in vertical movement among instruments. The system generated detailed spatiotemporal data suitable for surgical workflow analysis and training support.ConclusionThis method produces statistical outputs that may enhance surgical safety by improving procedural organisation and resource allocation. The proposed computer vision framework represents a cost-effective advancement in surgical digitisation, enabling accurate instrument tracking using standard video data and supporting future optimisation of orthopaedic surgical practice with significant implications for clinical research.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261489510"},"PeriodicalIF":2.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Web Application to Calculate the Number and Proportion of Procedures Submitted to Medicare Part B by Advanced Practice Providers. 开发一个Web应用程序来计算由高级实践提供者提交给医疗保险B部分的程序的数量和比例。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-09-12 DOI: 10.1177/15533506261485691

Max J Hyman, Will Engler, Parth K Modi

{"title":"Development of a Web Application to Calculate the Number and Proportion of Procedures Submitted to Medicare Part B by Advanced Practice Providers.","authors":"Max J Hyman, Will Engler, Parth K Modi","doi":"10.1177/15533506261485691","DOIUrl":"https://doi.org/10.1177/15533506261485691","url":null,"abstract":"BackgroundThe role of advanced practice providers (APPs) in procedural care in the U.S. is growing. However, research comparing outcomes of procedures performed by APPs vs physicians is limited.ObjectiveTo develop a free web application for publicly available data which calculates the number and proportion of any procedure or set of procedures submitted to Medicare Part B by APPs.MethodsWe designed the web application with as simple infrastructure as possible. The application is a static site with two external dependencies and contained in HTML and JavaScript files. The data source is the Physician/Supplier Procedure Summary from CMS. This annual public dataset between 2010 and 2025 includes summary Medicare Part B fee-for-service claims. We implemented a suite of validation tests. The most important test compared the output of the application to the output from downloading data from CMS and processing it in a separate pipeline.ResultsThe free web application may be accessed in common internet browsers at https://open-hsr.github.io/advanced-practice-providers/, does not require data to be downloaded or processed in statistical software, and incorporates all publicly available data. The user inputs up to twenty-five HCPCS procedure codes, and the output includes a line chart and downloadable CSV file.ConclusionAs the role of APPs in procedural care in the U.S. grows, the output of the application can identify procedures for which comparative effectiveness research by clinician type may be useful and can be incorporated into proposals requesting resources to design and conduct that research.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261485691"},"PeriodicalIF":2.2,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large Language Models for Breast Cancer Education: A Comparative Analysis of Quality, Reliability and Readability. 乳腺癌教育的大型语言模型：质量、可靠性和可读性的比较分析。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-09-09 DOI: 10.1177/15533506261488588

Burak Altunpak

{"title":"Large Language Models for Breast Cancer Education: A Comparative Analysis of Quality, Reliability and Readability.","authors":"Burak Altunpak","doi":"10.1177/15533506261488588","DOIUrl":"https://doi.org/10.1177/15533506261488588","url":null,"abstract":"BackgroundPatients increasingly consult artificial intelligence (AI) tools for breast cancer information. While Large Language Models (LLMs) enhance information accessibility, their accuracy, reliability, and alignment with patient health literacy remain critical concerns. This study compared the quality, reliability, and readability of breast cancer-related responses generated by ChatGPT and Gemini.MethodsIn this cross-sectional study, conducted between March 20 and March 31, 2026, 40 questions spanning diagnosis, treatment, genetics, and follow-up were submitted to ChatGPT-5.3 and Gemini 3.0 Flash. Three independent surgeons evaluated the responses in a double-blinded manner using the modified DISCERN (mDISCERN) for reliability and Global Quality Score (GQS) for content quality assessment. Readability was assessed via Flesch Reading Ease (FRES), Flesch-Kincaid Grade Level (FKGL), Gunning Fog Index (GFI), and Simple Measure of Gobbledygook (SMOG) indices.ResultsGemini demonstrated statistically significant superiority over ChatGPT in both GQS (4.35 ± 0.30 vs 3.90 ± 0.29; P < .001) and mDISCERN (3.63 ± 0.58 vs 3.02 ± 0.48; P < .001) scores. In readability analysis, Gemini exhibited higher FRES (53.90 vs 45.13) and lower FKGL (9.31 vs 10.91) values, indicating enhanced patient accessibility (P < .05). For both models, the \"Diagnosis\" category yielded the highest readability, whereas \"Treatment\" scored the lowest. Inter-rater reliability for mDISCERN was moderate (ICC = 0.595).ConclusionsGemini significantly outperforms ChatGPT in response quality, reliability, and linguistic accessibility for breast cancer education. However, both models exceed the recommended sixth-grade reading level, indicating suboptimal optimization for general health literacy. While LLMs serve as promising auxiliary tools, expert supervision and cross-validation remain mandatory to ensure patient safety.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261488588"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ChatGPT 4.o Responses to Commonly Asked Colon and Rectal Cancer Questions From a Patient Perspective. ChatGPT 4。从病人的角度回答结肠癌和直肠癌的常见问题。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-09-08 DOI: 10.1177/15533506261485700

Alyssa Habermann, Tania Gupta, Stephen Cohen, Syed Shah, Adam Khader, Kathryn Fong, Michael F Amendola

{"title":"ChatGPT 4.o Responses to Commonly Asked Colon and Rectal Cancer Questions From a Patient Perspective.","authors":"Alyssa Habermann, Tania Gupta, Stephen Cohen, Syed Shah, Adam Khader, Kathryn Fong, Michael F Amendola","doi":"10.1177/15533506261485700","DOIUrl":"https://doi.org/10.1177/15533506261485700","url":null,"abstract":"IntroductionPatients are increasingly turning to large language models (LLMs) such as ChatGPT for medical guidance, prompting concerns around medical competence. This study assesses the proficiency of ChatGPT 4.o in answering patient questions regarding the surgical management of colon and rectal cancer.MethodsChatGPT 4.o was prompted with 10 patient-based questions regarding the surgical management of colon and rectal cancer. A five-surgeon panel evaluated each response for completeness, accuracy, and effective communication (5-point Likert scale). ANOVA was used to compare difference between response categories and unpaired t-test was used to compare scores between colon and rectal cancers.ResultsThe average scores of all colon and rectal questions were 13.02 ± 0.57 and 12.94 ± 0.55, respectively (out of 15). The highest scoring colon question related to postoperative length of stay (13.80 ± 1.30) and the lowest scoring colon question pertained to operative time (12.20 ± 1.92). The highest scoring rectal questions discussed bowel continence and return to normal activities (13.60 ± 1.34 and 13.60 ± 1.52) and the lowest scoring rectal question explained surgical procedures for removing rectal cancer (11.80 ± 2.28). Average scores (out of 5) for completeness, accuracy, and communication were 4.56 ± 0.69, 4.35 ± 0.73, and 4.16 ± 0.71, respectively (P < .001). There was no significant difference between evaluator scores for colon and rectal questions (P > .05).ConclusionsChatGPT 4.o is capable of answering commonly asked patient questions regarding colon and rectal cancer with reasonable completeness, accuracy, and effective communication with statistically significant variations between these categories.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261485700"},"PeriodicalIF":2.2,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What Is the Impact of Robotic Abdominal Surgery on Quality of Life? 机器人腹部手术对生活质量的影响是什么？

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-09-03 DOI: 10.1177/15533506261486595

Joseph S Flanagan, Akil E Anthony, Zoltan H Nemeth

引用次数: 0

An Evidence Map of Animal Studies on Absorbable Meshes for Abdominal Wall and Inguinal Hernia Repair: Material Trends, Model Selection, and Translational Gaps. 用于腹壁和腹股沟疝修补的可吸收网的动物研究证据图：材料趋势、模型选择和翻译差距。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-08-19 DOI: 10.1177/15533506261476207

Yusha Liu, Shaowei Yi, Yanli Liu, Zhe Wang, Fengxing Ding, Wanxian Du, Yating Luo, Ying Ren, Zihan Wang, Yajuan Wang, Jianhua Ruan, Muting Niu, Guangmei Xie, Wenbo Liu, Bin Ma

{"title":"An Evidence Map of Animal Studies on Absorbable Meshes for Abdominal Wall and Inguinal Hernia Repair: Material Trends, Model Selection, and Translational Gaps.","authors":"Yusha Liu, Shaowei Yi, Yanli Liu, Zhe Wang, Fengxing Ding, Wanxian Du, Yating Luo, Ying Ren, Zihan Wang, Yajuan Wang, Jianhua Ruan, Muting Niu, Guangmei Xie, Wenbo Liu, Bin Ma","doi":"10.1177/15533506261476207","DOIUrl":"https://doi.org/10.1177/15533506261476207","url":null,"abstract":"ObjectiveTo systematically map the landscape of animal studies on absorbable meshes for hernia repair published from 2003 to 2025, with a focus on material types, animal models, follow-up durations, and outcome measures, and to access their implications for clinical translation.MethodsStudies published between 2003 and 2025 involving animal models of hernia repair were systematically identified and screened. Data on material classification, animal species, follow-up duration, and outcome domains were extracted and synthesized using an evidence mapping framework.ResultsA total of 165 studies covering 183 mesh types were included. Self-fabricated meshes were more commonly used than commercial products (62.3% vs 37.7%), with biologically derived materials predominating. Rats and rabbits were the primary experimental models, while follow-up durations were generally short, limiting long-term performance assessment. Although large-animal studies remained limited, their use-particularly miniature pigs and nonhuman primates-has increased in recent years due to greater physiological relevance. Histological outcomes and postoperative complications were most frequently reported, whereas long-term functional outcomes were rarely assessed. Substantial heterogeneity in scoring systems and evaluation methods was observed across studies.ConclusionPreclinical research on hernia repair materials is largely dominated by short-term, small-animal experiments using self-fabricated biologically derived meshes. Greater emphasis on large-animal models, extended follow-up, and standardized, multi-level outcome frameworks is needed to strengthen translational relevance.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261476207"},"PeriodicalIF":2.2,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

vNOTES for Diagnostic Peritoneal Exploration in Peritoneal Carcinomatosis of Unknown Primary: A Prospective Pilot Feasibility Study. vNOTES用于未知原发腹膜癌的腹膜探查诊断：一项前瞻性试点可行性研究。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-08-16 DOI: 10.1177/15533506261476468

Mehmet Karahan, Emre Mat, Cemal Hacıalioğlu, Fatih Şanlıkan, Murat Levent Dereli, Pınar Birol İlter, Gazi Yıldız, Hasan Fehmi Küçük

{"title":"vNOTES for Diagnostic Peritoneal Exploration in Peritoneal Carcinomatosis of Unknown Primary: A Prospective Pilot Feasibility Study.","authors":"Mehmet Karahan, Emre Mat, Cemal Hacıalioğlu, Fatih Şanlıkan, Murat Levent Dereli, Pınar Birol İlter, Gazi Yıldız, Hasan Fehmi Küçük","doi":"10.1177/15533506261476468","DOIUrl":"https://doi.org/10.1177/15533506261476468","url":null,"abstract":"BackgroundPeritoneal carcinomatosis (PC) of unknown primary origin remains a diagnostic challenge, often requiring surgical exploration and tissue sampling. Vaginal natural orifice transluminal endoscopic surgery (vNOTES) has emerged as a minimally invasive access route; however, evidence regarding its feasibility for diagnostic peritoneal assessment in this setting is limited. This study aimed to evaluate the technical feasibility of vNOTES for peritoneal exploration, biopsy acquisition, and intraoperative estimation of the Peritoneal Cancer Index (PCI).MethodsThis prospective single-center pilot study included 11 female patients with radiologically suspected PC and unknown primary malignancy. All patients underwent peritoneal exploration and biopsy via vNOTES. Intraoperative PCI was recorded and descriptively compared with preoperative radiological PCI. Perioperative outcomes and early postoperative complications were assessed.ResultsvNOTES access, peritoneal exploration, and biopsy acquisition were successfully completed in all patients without conversion. Adequate tissue samples were obtained in all cases. The mean surgical PCI was 28.9 ± 4.0, indicating advanced disease. Radiological and surgical PCI assessments showed apparent high concordance, likely influenced by the uniformly advanced disease burden. No intraoperative or major postoperative complications occurred, and all patients had an uncomplicated postoperative course.ConclusionsvNOTES appears to be a technically feasible minimally invasive approach for diagnostic peritoneal exploration and biopsy in selected patients with PC of unknown primary origin. These preliminary findings require validation in larger comparative studies to determine safety and clinical utility.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261476468"},"PeriodicalIF":2.2,"publicationDate":"2026-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computer Vision Applications in Laparoscopic Cholecystectomy: Are We Ready? A Systematic Review. 计算机视觉在腹腔镜胆囊切除术中的应用：我们准备好了吗？系统评价。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-08-13 DOI: 10.1177/15533506261477478

Intekhab Hossain, Abdulrahman Alomar, Daniel Tham, Hojjat Salehinejad, Omar M Ghanem, Amin Madani, Simon Laplante

{"title":"Computer Vision Applications in Laparoscopic Cholecystectomy: Are We Ready? A Systematic Review.","authors":"Intekhab Hossain, Abdulrahman Alomar, Daniel Tham, Hojjat Salehinejad, Omar M Ghanem, Amin Madani, Simon Laplante","doi":"10.1177/15533506261477478","DOIUrl":"https://doi.org/10.1177/15533506261477478","url":null,"abstract":"This systematic review evaluates current computer vision models and their applications in laparoscopic cholecystectomy. Using PRISMA guidelines, we analyzed studies reporting on primary computer vision model applications in laparoscopic cholecystectomy, from inception to March 2026. A total of 85 studies were included: workflow analysis (n = 26), anatomy recognition and segmentation (n = 14), safety assessment (n = 14), instrument detection (n = 12), tissue/image characterization (n = 7), event detection and scene understanding (n = 6), and surgical performance assessment (n = 6). The performance of the computer vision models in the studies was heterogeneous, with accuracy, F1-score, mean average precision, Dice coefficient, mean absolute error, and area under the receiver operating characteristic curve being commonly reported. Despite strong model performances in several studies, implementation in the clinical setting remains a challenge. We highlight the need for standardized model performance reporting, broader external and multi-institutional validation of models, and coordinated frameworks for safe and effective implementation of computer vision models in laparoscopic cholecystectomy.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261477478"},"PeriodicalIF":2.2,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-Time Three-Dimensional Optical Coherence Tomography Guidance for Transbronchial Biopsy: A Proof-of-Concept Ex Vivo Study. 实时三维光学相干断层扫描指导经支气管活检：概念验证离体研究。

IF 2.2 4区医学

Surgical Innovation Pub Date : 2026-08-12 DOI: 10.1177/15533506261477022

Takayasu Ito, Tomoya Baba, Hayata Kimura, Shota Nakamura, Toyofumi Fengshi Chen-Yoshikawa, Makoto Ishii

{"title":"Real-Time Three-Dimensional Optical Coherence Tomography Guidance for Transbronchial Biopsy: A Proof-of-Concept Ex Vivo Study.","authors":"Takayasu Ito, Tomoya Baba, Hayata Kimura, Shota Nakamura, Toyofumi Fengshi Chen-Yoshikawa, Makoto Ishii","doi":"10.1177/15533506261477022","DOIUrl":"https://doi.org/10.1177/15533506261477022","url":null,"abstract":"Background/needConventional bronchoscopy has a limited ability to localize and accurately target peripheral pulmonary lesions (PPLs) because these lesions are not endoscopically visible, and obtaining three-dimensional (3D) images of the position of sampling instruments relative to the target lesion in real time is also difficult. Three-dimensional optical coherence tomography (3D-OCT) which have the special resolution of 10-µm provides higher spatial resolution than intravascular ultrasound of 100-µm for intravascular imaging and is used to support the assessment and treatment of coronary artery stenosis. In the respiratory system, 3D-OCT guidance may enable real-time 3D analysis of the spatial relationship between the sampling instrument and the target lesion during transbronchial lung biopsy (TBB), which is difficult to achieve with two-dimensional radial endobronchial ultrasound (r-EBUS).Methodology and device descriptionWe evaluated whether 3D-OCT could visualize pseudo-lesions and enable real-time assessment of the spatial relationship between the sampling instrument and the pseudo-lesion during TBB.Preliminary resultsIn three excised pig lungs, a 3D-OCT probe and ultrathin biopsy forceps were simultaneously advanced through a guide sheath placed in the bronchus to a pseudo-lesion per an excised pig lung. The probe visualized the spatial relationship between the sampling instrument and the pseudo-lesion in real time. Furthermore, 3D-OCT-guided TBB was successfully performed in three consecutive biopsies per a pseudo-lesion.Current status3D-OCT-guided TBB was feasible in an ex vivo model for sampling target lesions. These results indicate that 3D-OCT-guided bronchoscopy may help to provide the special relationship of targeting and sampling of PPLs.","PeriodicalId":22095,"journal":{"name":"Surgical Innovation","volume":" ","pages":"15533506261477022"},"PeriodicalIF":2.2,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0