Supportive Care in Cancer最新文献

{"title":"The prognostic impact of preoperative nutritional status on postoperative complications and overall survival in patients with resectable pancreatic cancer.","authors":"Elif Gündoğdu, Betül Nalan Karahan, Ahmet Murat Şendil, Akile Zengin, Murat Ulaş, Mehmet Kılıç","doi":"10.1007/s00520-025-09303-1","DOIUrl":"10.1007/s00520-025-09303-1","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study is to demonstrate the prognostic impact of preoperative nutritional status indicators, including prognostic nutritional index (PNI), hemoglobin-albumin-lymphocyte-platelet (HALP) score, sarcopenia index (SI), and bone mineral density (BMD) values, on postoperative complications and survival in patients with resectable pancreatic cancer (PC).</p><p><strong>Materials and methods: </strong>The medical data and computed tomography (CT) images of 85 patients who undergone surgery for PC between January 2017 and 2023 were evaluated retrospectively. Patients were grouped according to the presence or absence of sarcopenia and osteoporosis, high and low PNI and HALP scores. The groups were compared in terms of the complication development rate, 30- and 90-day mortality, and 5-years overall survival (OS). Sarcopenia and osteoporosis were determined from CT images (sarcopenia index used for sarcopenia, bone mineral density for osteoporosis).</p><p><strong>Results: </strong>Except from OS (p < 0.0001), no differences were found between sarcopenic and non-sarcopenic groups in terms of postoperative complications, 30- and 90-day mortality (p = 0.775, p = 0.704, p = 0.196, respectively). There were no differences between the groups with and without osteoporosis in terms of the presence of postoperative complications, 30- and 90-day mortality, and OS (p = 0.770, p = 0.608, p = 0.196, p = 0.09, respectively) as low and high HALP score groups (p = 0.236, p = 0.696, p = 0.299, p = 0.45, respectively). Except from a 30-day mortality (p = 0.03), no differences were found between low and high PNI groups in terms of postoperative complications, 90-day mortality, and OS (p = 0.82, p = 0.09, p = 0.18, respectively).</p><p><strong>Conclusion: </strong>PNI may be used as prognostic data for early postoperative mortality, while sarcopenia may be indicative of 5-year OS in patients with resectable PC. Our results suggest that providing nutritional support may potentially improve prognosis. Future studies, in which other factors effective in prognosis are evaluated together with nutritional status, will show more information on this subject.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"240"},"PeriodicalIF":2.8,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body image as a mediator between bowel dysfunction symptoms and psychological outcomes among patients with colorectal cancer.","authors":"Van Du Phung, Su-Ying Fang","doi":"10.1007/s00520-025-09299-8","DOIUrl":"10.1007/s00520-025-09299-8","url":null,"abstract":"<p><strong>Background: </strong>Colorectal cancer (CRC) survivors commonly experience bowel dysfunction symptoms because of treatment, leading to psychological distress. While previous studies have focused on managing physical symptoms and the impact of a stoma on psychological outcomes, CRC patients without a stoma may also suffer from psychological distress, including body image distress due to their bowel dysfunction symptoms. Body image distress may mediate the relationship between bowel dysfunction symptoms and psychological outcomes in CRC patients.</p><p><strong>Objectives: </strong>This study aims to (1) identify bowel dysfunction symptoms, body image distress, and psychological outcomes in CRC survivors and (2) examine the mediating role of body image in the relationship between bowel dysfunction symptoms and psychological outcomes.</p><p><strong>Methods: </strong>A cross-sectional and correlational design was employed, and CRC survivors completed the Low Anterior Resection Syndrome (LARS) Score, Body Image Scale (BIS), and Hospital Anxiety and Depression Scale (HADS) questionnaires. The mediated role of body image was examined using Hayes' PROCESS macro.</p><p><strong>Results: </strong>A total of 193 CRC patients provided data, with 65.8% reporting experiencing bowel dysfunction symptoms, 44.6% reporting body image distress, and 40.4% experiencing anxiety and depression. Body image was found to partially mediate the effect of bowel dysfunction symptoms on both anxiety (β = 0.0446, 95% CI = 0.0061, 0.0968) and depression (β = 0.0411, 95% CI = 0.0034, 0.0941).</p><p><strong>Conclusion and implications: </strong>The significant mediating role of body image underscores the importance of addressing both bowel dysfunction symptoms and body image distress. Healthcare professionals should integrate both physical and psychological aspects to promote psychological well-being.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"237"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of anxiety and chemotherapy side effects on quality of life in patients with malignant lymphoma.","authors":"Yuta Teshigawara, Kazuhide Tanaka, Tomoya Tachi, Masataka Shishido, Seiji Inoue, Teppei Makino, Yoshihiro Noguchi, Junichi Kitagawa, Takashi Mizui, Hitomi Teramachi, Masahiro Yasuda, Tomoaki Yoshimura, Senji Kasahara","doi":"10.1007/s00520-025-09294-z","DOIUrl":"10.1007/s00520-025-09294-z","url":null,"abstract":"<p><strong>Purpose: </strong>There are no reports on the side effects of chemotherapy on the quality of life (QOL) of patients with malignant lymphoma or on the intensity of anxiety affecting these side effects. We conducted a prospective observational study to evaluate the association between anxiety, chemotherapy side effects, and QOL in patients with malignant lymphoma undergoing their first cancer chemotherapy treatment.</p><p><strong>Methods: </strong>We studied anxiety intensity, side effects, and QOL changes in 60 patients with malignant lymphoma who received their first course of initial chemotherapy at Gifu Municipal Hospital (Japan) between January 2021 and December 2022. Questionnaires were administered before and after the first chemotherapy course. The questionnaires included patient information and the STAI-JYZ, EQ-5D-5L, and EORTC QLQ-C30. EQ-5D-5L utility values and EORTC QLQ-C30 item scores were compared before and after the first chemotherapy course. The proportion of patients with issues with the five EORTC QLQ-C30 items was compared before and after the first chemotherapy. QOL was compared based on side effects and severity. QOL based on anxiety intensity was also compared.</p><p><strong>Results: </strong>The number of patients reporting problems with their usual activities significantly increased after the first chemotherapy course. Emotional functioning on the EORTC QLQ-C30 significantly increased after the first chemotherapy course. Patients' anxiety, depression, and pain decreased after the first course of chemotherapy. Patients with anorexia had lower utility values and EORTC QLQ-C30 Global health status. The utility values of the anxiety group increased significantly after chemotherapy.</p><p><strong>Conclusion: </strong>Chemotherapy reduced activity but improved mental and psychological status. Anorexia negatively affects QOL and improves the QOL of patients with anxiety undergoing chemotherapy. This study clarified the relationship between anxiety, side effects, and QOL associated with cancer chemotherapy in patients with malignant lymphoma.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"238"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and safety of impact-loading exercise in patients with multiple myeloma-a pilot study.","authors":"Anne Kollikowski, Marei Schallock, Ruben Ringeisen, Dirk Hasenclever, Lothar Seefried, Jan-Peter Grunz, Damir Zubac, Claudia Löffler, Freerk T Baumann, Franziska Jundt","doi":"10.1007/s00520-025-09287-y","DOIUrl":"10.1007/s00520-025-09287-y","url":null,"abstract":"<p><strong>Purpose: </strong>Patients with multiple myeloma (MM) develop osteolytic lesions with fractures, pain, and impaired quality of life. Preclinical data show an anabolic effect of loading exercise in osteolytic lesions of MM. This 6-month pilot study evaluated feasibility and safety of impact-loading exercise in patients with MM after assessment of spinal stability.</p><p><strong>Methods: </strong>We assigned 20 patients to perform 45 min of guided impact-loading exercise twice a week and home-based training once a week or stretching exercise twice a week. Primary endpoint was assessment of feasibility and safety. Secondary endpoints were assessments of physical performance, quality of life, and bone remineralization.</p><p><strong>Results: </strong>Of 77 eligible patients with MM, 26% accepted participation. In the impact group, 9/12 and in the stretching group 7/8 patients completed training with adherence rates of 65.8 and 81.1%. Ninety percent of the stamping and jumping exercises were performed with increasing intensity from the prescribed training volume of ≥ 100%. Low severity pain events were reported after 32.9% of impact sessions. No serious adverse events were observed. After 6 months, 6-minute walk distance increased in the impact group by 35 m and in the stretching group by 46 m, and chair-rise test improved in the stretching group by 1.7 s. Global health status increased by 24.9% in the impact group, and functional scale by 31.9% in the stretching group based upon EORTC QLQ-C30. No signs of bone remineralization were observed in computed tomography.</p><p><strong>Conclusion: </strong>Impact training is feasible and appears to be safe in selected MM patients.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"235"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of prophylactic gabapentin in managing oral mucositis pain in patients undergoing non-surgical management of head and neck tumors.","authors":"Virda Baig, Shehla F Hashmi, Maryam Altuhafy, Junad Khan","doi":"10.1007/s00520-025-09298-9","DOIUrl":"10.1007/s00520-025-09298-9","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review aimed to assess the effectiveness of prophylactic gabapentin in managing pain related to mucositis developed in patients with head and neck tumors undergoing chemoradiation.</p><p><strong>Methods: </strong>An electronic search of indexed databases, including PubMed, EMBASE, Scopus, ISI Web of Knowledge, Cochrane Library, and Google Scholar, was performed without time restriction until April 2024. Risk of Bias (RoB) assessment was conducted using the Cochrane tool. This study was registered in the PROSPERO database (CRD42024550242).</p><p><strong>Results: </strong>An initial electronic and manual search revealed 1,786,350 manuscripts. Five randomized controlled trials (RCTs) were included following the eligibility criteria. In one study, gabapentin was statistically significant in reducing pain; however, a positive trend was observed in three studies with no statistical significance. Four studies showed a trend either in reduction or a delay in opioid usage. The overall quality of life was significantly improved in one study, whereas a positive trend was observed in two studies and neutral in two. Future standardized studies with larger sample sizes are required to understand better the effectiveness of gabapentin in patients undergoing cancer management of the head and neck region.</p><p><strong>Conclusion: </strong>Overall, there was a positive trend in reducing oral mucositis-related pain in patients undergoing chemoradiation of the head and neck region, with only one study reaching statistical significance. Gabapentin also demonstrated effectiveness in reducing opioid dependency, delaying opioid initiation, and managing early pain, with tolerable side effects in most studies and improving the overall quality of life. Future studies with standardized protocols and higher sample sizes are required to validate these results further.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"236"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Language understanding and preferences when reporting symptoms for pediatric patients receiving cancer treatments and their guardians.","authors":"Ida Mehrdadi, Zakia Joseph-Frederick, Ariana Petrazzini, Julia Apolot, Ana Simone Roshdi, Neeraj Dhaliwal, Misimi Sanni, Amy D Lu, L Lee Dupuis, Lillian Sung","doi":"10.1007/s00520-025-09296-x","DOIUrl":"10.1007/s00520-025-09296-x","url":null,"abstract":"<p><strong>Purpose: </strong>The Symptom Screening in Pediatrics Tool (SSPedi) was developed to facilitate symptom assessment among pediatric patients receiving cancer treatments; limited translations are available. The objective was to describe, among non-English pediatric patients receiving cancer treatments and non-English guardians, the language in which they understood symptoms and their language preferences for SSPedi completion.</p><p><strong>Methods: </strong>In this single-center study, we included patients receiving cancer treatments aged 8-18 years or guardians of patients 2-18 years with non-English first languages. A single interview was conducted where participants were asked whether they understood the words for each of the 15 SSPedi symptoms in their first language, English, or both. We also asked about the importance of SSPedi translation in their first language.</p><p><strong>Results: </strong>We included 50 pediatric patients and 155 guardians speaking 49 unique first languages. The number who knew a symptom only in their first language ranged from 2/50 (4.0%) to 6/50 (12.0%) for pediatric patients and ranged from 5/155 (3.2%) to 16/155 (10.3%) for guardians. In general, it was more common for pediatric patients to know a symptom only in English compared to guardians. The number who stated translation into their first language was very or extremely important was 16/50 (32.0%) for pediatric patients and 50/155 (32.2%) for guardians.</p><p><strong>Conclusion: </strong>While most non-English patients and guardians understood SSPedi symptoms in English, some will require translation in their first language. Given the large number of languages, meeting the needs of those who require translation will require novel approaches.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"233"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of enteral nutrition in cancer patients - methodological adjustments and recommendations.","authors":"Galip Can Uyar, Orhun Akdoğan, Osman Sütcüoğlu","doi":"10.1007/s00520-025-09301-3","DOIUrl":"10.1007/s00520-025-09301-3","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"234"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role and perception of healthcare professionals in referring cancer patients to online cognitive behavioral therapy for insomnia.","authors":"Louise Zanni, Jonathan Journiac, Josée Savard, Estelle Guerdoux, Guilhem Paillard-Brunet, Léonor Fasse, Jean-Bernard Le Provost, Cécile Charles, Sarah Dauchy, Diane Boinon","doi":"10.1007/s00520-025-09284-1","DOIUrl":"10.1007/s00520-025-09284-1","url":null,"abstract":"<p><strong>Purpose: </strong>Insomnia represents a major issue in oncology, which can be successfully treated by online Cognitive-Behavioural Therapy for Insomnia, such as the Insomnet program. However, promoting its successful implementation in routine care requires healthcare providers' involvement. This study aimed to explore healthcare professionals' perceptions of this online program.</p><p><strong>Methods: </strong>This qualitative study was a part of the French Sleep-4-All-2.0 multicentric study. It explored, through two focus groups including 19 healthcare professionals of three cancer centers, their perceptions regarding their role in patient referral, and the perceived barriers and facilitators in accessing this type of intervention. The content of the focus groups was subjected to a descriptive thematic analysis.</p><p><strong>Results: </strong>Four major themes were identified: (1) ambivalent representations of online tools (including patients convinced by remote intervention, evolution of representations in relation to the health context, adapted to sleep disorders, professionals' preconceptions of online tools), (2) barriers to implementation (including few perceived barriers, forgetting patients' particularities, professionals' lack of knowledge, a possible threat to the patient-caregiver relationship, financial cost), (3) levers for implementation (including real benefits for patients, professionals who feel confident, preserved patient-caregiver relationship, institutional innovations to remedy dysfunctions), and (4) professional involvement in implementation (what they need, what to avoid, what they already do, what they see themselves doing).</p><p><strong>Conclusion: </strong>Online (healthcare) services were reported to help increase access to healthcare, but that should not replace the relationship between patients and healthcare professionals. All professionals must be informed and trained to refer patients to these programs.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"239"},"PeriodicalIF":2.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double burden: financial toxicity in patients with advanced soft tissue sarcoma at the start of first-line palliative chemotherapy: baseline data from the HOLISTIC study.","authors":"E Roets, E Younger, R L Jones, D den Hollander, I M E Desar, R J Young, A W Oosten, J J de Haan, H Gelderblom, N Steeghs, W T A van der Graaf, O Husson","doi":"10.1007/s00520-025-09248-5","DOIUrl":"10.1007/s00520-025-09248-5","url":null,"abstract":"<p><strong>Purpose: </strong>The HOLISTIC study assessed health-related quality of life (HRQoL) in advanced soft tissue sarcoma (STS) patients receiving first-line palliative chemotherapy. The secondary objective discussed here is to evaluate baseline self-reported financial difficulties and associated sociodemographic factors and global health status (GHS), compare financial toxicity between patients in the United Kingdom (UK) and the Netherlands (NL), and evaluate the consequences of financial toxicity.</p><p><strong>Methods: </strong>This prospective study included 72 UK and 65 NL patients. Financial toxicity was evaluated by the financial difficulties scale of the EORTC QLQ-C30. Associated factors (i.e., country, gender, educational level, relationship status, employment changes, income, age, time since diagnosis, and GHS) were analyzed using descriptive analysis, Chi-square tests, and univariate and multivariate logistic regression.</p><p><strong>Results: </strong>Median participant age was 62 (range: 27-79) years, and gender distribution was equal. 58% of UK and 48% of NL patients had no income or a monthly income ≤ £/€ 2000 (p = 0.417). Self-reported additional costs for medication (31% vs. 9%, p < 0.001) and parking (75% vs. 41%, p < 0.001) were more prevalent among Dutch than UK patients. Travel expenses were similar: 68% in NL and 66% in UK. Univariate analysis showed an increased risk of financial toxicity in UK patients (40% vs. 22% [NL], p = 0.023), single patients (52% vs. 27% [with partner], p = 0.014), and those with a change in employment status (46% vs. 24% [no change], p = 0.019). In UK patients, multivariate analysis indicated lower odds for financial toxicity for patients with a high income (OR 0.207, p = 0.031) and higher odds for patients with a worse GHS (OR 5.171, p = 0.012), whereas in NL, higher odds were seen for male (OR 13.286, p = 0.027) and single (OR 41.735, p = 0.007) patients.</p><p><strong>Conclusion: </strong>Financial toxicity was common among advanced STS already at the start of palliative chemotherapy, influenced by factors such as residence country, income, relationship status, gender, and GHS. Timely interventions are needed to address financial challenges in this population.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"228"},"PeriodicalIF":2.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11865148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is the evidence for dietary modification in the management and prevention of malignant bowel obstruction? A scoping review.","authors":"Ellie Ware, Laura Tookman, Erin Stella Sullivan, Lina Johansson, Iain McNeish, Lindsey Allan","doi":"10.1007/s00520-025-09279-y","DOIUrl":"10.1007/s00520-025-09279-y","url":null,"abstract":"<p><strong>Purpose: </strong>Dietary modification is one tool in the multidisciplinary and multi-faceted management of malignant bowel obstruction (MBO). However, the evidence for this has not been systematically explored and no guidelines currently exist. The purpose of this review was to identify the type and breadth of published evidence available to support the use of dietary modification in MBO, and to identify key characteristics of dietary interventions and outcome measures used in evaluating these interventions.</p><p><strong>Methods: </strong>Systematic searches of three databases were conducted, last in September 2024. Title and abstract screening and full-text review were conducted before data were extracted using a data extraction tool.</p><p><strong>Results: </strong>Only seven records met the criteria for inclusion. Quality of interventions was low, with four abstracts, one retrospective review and two feasibility studies identified. Most interventions focused on gynaecological cancers, where MBO is most prevalent. Key characteristics of dietary modification included a low-fibre diet and modification of the texture of the diet. These approaches were often used in conjunction and in a stepwise manner (progressing from liquid to soft to low-fibre diet). All records reported benefit of dietary modification, but with limited justification. The number, type and quality of records retrieved might reflect that this is a novel area of research, with local practice and clinical experience being published as abstracts. We found no methodologically robust, large-scale interventions.</p><p><strong>Conclusion: </strong>This review demonstrates a lack of evidence to support the use of dietary modification in MBO. High-quality studies assessing the efficacy and impact of dietary modification are needed to support the advice commonly being provided in clinical settings. However, this research is ethically and logistically challenging to conduct. Nutritional management guidelines based on expert consensus might be a useful resource for clinicians managing MBO given the lack of research evidence currently available to inform practice.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"231"},"PeriodicalIF":2.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}