Supportive Care in Cancer最新文献

{"title":"The \"dark side\" of self-management in cancer patients: the role of personality.","authors":"Ilaria Durosini, Dario Monzani, Marianna Masiero, Gabriella Pravettoni","doi":"10.1007/s00520-025-09247-6","DOIUrl":"https://doi.org/10.1007/s00520-025-09247-6","url":null,"abstract":"<p><p>The increasing number of people living with chronic illnesses is an important healthcare issue for clinical and economic reasons. Fostering patients' self-management and responsibility for their care appears to be a strategy for promoting patients' quality of life over time. In this context, patients are asked to actively identify challenges in their illness and actively manage their health (i.e., self-management). However, involving patients in their health management is not free from psychological factors. For example, personality traits can facilitate or hinder the effective implementation of self-management within cancer patients while also impacting patient engagement, commitment to treatments, and decision-making processes about health. In this commentary, we try to shed light on the \"dark side\" of self-management. The term \"dark side\" is related to the absence of knowledge, comparable to the dark hemisphere of the Moon, which is not visible from the Earth and so poorly understood. Specifically, this commentary aims to describe the unexplored aspects and unsolved issues related to self-management, exploring the side not visible to Earth-bound observers related to the possible role of personality in the promotion of self-management in people with a history of cancer. Attention to personality traits may help promote better self-management for cancer patients and guarantee a higher quality of life, despite their chronic condition.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"304"},"PeriodicalIF":2.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor to 'The association between physical activity levels and quality of life in elderly lung cancer patients undergoing chemotherapy in China: a cross‑sectional study.'","authors":"Bediz Kurt İnci","doi":"10.1007/s00520-025-09324-w","DOIUrl":"https://doi.org/10.1007/s00520-025-09324-w","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"306"},"PeriodicalIF":2.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of disease duration in the use of complementary and integrative medicine for cancer-related fatigue: a cross-sectional study.","authors":"Yağmur Artan, Gökhan Sezgin, İrem Bulut, Yasemin Yildirim","doi":"10.1007/s00520-025-09367-z","DOIUrl":"10.1007/s00520-025-09367-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the use of complementary and integrative medicine among cancer patients in Turkey for managing fatigue and to examine the moderating effect of disease duration on the relationship between fatigue levels and patients' attitudes toward complementary and integrative medicine.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 231 cancer patients recruited from a chemotherapy center in western Turkey. Participants completed sociodemographic forms, the Holistic Complementary and Alternative Medicine Questionnaire, and the Visual Analog Scale for Fatigue. Data were analyzed using linear regression and moderation analysis.</p><p><strong>Results: </strong>Among the participants, 38.5% reported using complementary and integrative medicine to manage fatigue, with biologically based treatments such as vitamin supplements and herbal tea being the most common. Regression analysis showed that younger age (p < 0.05), longer disease duration (p = 0.005), absence of complementary and integrative medicine-related complications (p < 0.001), and higher fatigue levels (p < 0.001) were significant predictors of positive attitudes toward complementary and integrative medicine. Additionally, disease duration moderated the relationship between fatigue levels and attitudes toward complementary and integrative medicine, with longer disease duration strengthening the association (B =  - 0.269, SE = 0.078, p = 0.001).</p><p><strong>Conclusion: </strong>The findings suggest that fatigue and prolonged disease duration significantly influence cancer patients' attitudes toward complementary and integrative medicine. Given the increasing use of complementary and integrative medicine, healthcare professionals should provide evidence-based guidance to ensure its safe and effective use. Future research should explore the long-term effects of complementary and integrative medicine on cancer-related fatigue.</p><p><strong>Relevance to clinical practice: </strong>This study highlights the importance of addressing cancer-related fatigue and recognizing the growing use of complementary and integrative medicine among cancer patients.</p><p><strong>Patient or public contribution: </strong>Patients were invited to complete questionnaires. Investigators explained the study's objectives and content and addressed any concerns raised during data collection.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"303"},"PeriodicalIF":2.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of aerobic cycling training in patients with gynaecologic cancer-related lower extremity lymphedema: A randomised comparative study.","authors":"Onur Kara, Gül Mete Civelek, Cansu Şahbaz Pirinççi, Rabia Tarlabölen, Meltem Dalyan","doi":"10.1007/s00520-025-09354-4","DOIUrl":"https://doi.org/10.1007/s00520-025-09354-4","url":null,"abstract":"<p><strong>Purpose: </strong>Lower extremity lymphedema (LEL) after gynaecological cancer is a chronic disease that affects quality of life and functionality negatively. Exercise therapies help to volume reduction and improved lower extremity functionality and quality of life in patients with lymphedema. However, studies on this subject were mostly focused on upper extremity lymphedema. In this study, we aimed to compare complete decongestive therapy (CDT) and CDT + cycle ergometry in terms of quality of life, lower extremity functionality and volume measurement in patients with gynaecological cancer-related lower extremity lymphedema.</p><p><strong>Methods: </strong>This study included 63 patients who gave written and verbal informed consent. The participants were randomly divided into two groups as cycling (32 patients) and non-cycling group (31 patients). Demographic and clinical data of patients were recorded. While patients in non-cycling group were treated with only CDT for 3 weeks, patients in cycling group were treated with CDT + cycle ergometry for 3 weeks. Cycle ergometry treatment was performed with Voit AT-200 Black Collection horizontal bike for 20 min. Exercise intensity was adjusted to 40-59% of heart rate reserve (HRR). Volume measurement was evaluated by circumference measurement method, quality of life was evaluated by Lymphedema Quality of Life Questionnaire (LYMQOL) and lower extremity functionality was evaluated by Lower Extremity Functional Scale (LEFS) in all participants.</p><p><strong>Result: </strong>Both cycling group and non-cycling group benefited from treatments in terms of volume reduction, LEFS and LYMQOL (function, appearance, symptom, mood and overall quality of life) values (p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001 and p < 0.001, respectively). In comparison of cycling and non-cycling groups, significant differences were found in favor of cycling group in terms of delta (Δ) extremity volume values (ml), Δ LEFS, Δ LYMQOL (function, appearance, symptom, mood and overall quality of life) (p = 0.04, p = 0.03, p < 0.001, p = 0.04, p = 0.002, p = 0.002, p < 0.001, p < 0.001 and p = 0.003, respectively). In other words; both groups benefited from treatments in terms of volume reduction, functionality and quality of life. However, benefit of cycling group is greater than benefit of non-cycling group.</p><p><strong>Conclusion: </strong>Aerobic exercise added to CDT in gynaecological cancer-related lower extremity lymphedema is effective in terms of volume reduction, improved lower extremity functionality and quality of life.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT06200948 .</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"302"},"PeriodicalIF":2.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body weight change in a medical supplement group in patients with early breast cancer during chemotherapy: a randomized, controlled trial.","authors":"Piyawan Tienchaiananda, Meitinarth Juntong, Photcharaphon Pintasiri, Sunatee Sa-Nguansai, Songwit Payapwattanawong, Kunlatida Maneenil","doi":"10.1007/s00520-025-09359-z","DOIUrl":"https://doi.org/10.1007/s00520-025-09359-z","url":null,"abstract":"<p><strong>Background: </strong>Patients with early-stage breast cancer usually receive anthracycline-based chemotherapy, known for its adverse effects such as neutropenia, nausea, and vomiting, which can result in a state of malnutrition. This study aimed to evaluate the efficacy of the use of oral nutritional support (ONS) in terms of body weight (BW), nutritional status, and quality of life (QOL) in patients with early-stage breast cancer receiving doxorubicin 60 mg/m² and cyclophosphamide 600 mg/m² for four cycles (4AC).</p><p><strong>Methods: </strong>Patients with early-stage breast cancer scheduled to undergo 4AC were randomly assigned in a 1:1 ratio to receive either ONS or dietary counseling as the standard of care (SOC). ONS provided 460 kcal and 17.1 g of protein per day over a 12-week period. BW at baseline and week 12 were measured, while QOL and nutritional status were evaluated at baseline and week 12 using the EORTC QLQ-C30 questionnaire and Patient-Generated Subjective Global Assessment. Complete blood count was performed every 3 weeks.</p><p><strong>Results: </strong>A total of 40 patients were enrolled. At baseline, most were in the normal weight to obese BMI range and were well-nourished. At week 12, patients in the ONS group had BW of 65.8 kg, which was 5.7 kg higher than that of their counterparts in the SOC group; however, the difference was not statistically significant (p = 0.167). Patients in the ONS group had a statistically significant increase in BW from 63.4 to 65.8 kg, (p = 0.004), while those in the SOC group had a non-significant increase from 59.6 to 60.1 kg, (p = 0.54). Patients in the SOC group experienced a statistically significant decline to being moderately malnourished, whereas their ONS counterparts did not. The QOL of global health status and function scales was maintained in both groups. Only appetite loss showed a statistically significant decline (in the SOC group). The mean absolute neutrophil count levels of patients in the ONS group tended to be higher than those in the SOC group at week 9; however, this difference was not statistically significant (p = 0.09).</p><p><strong>Conclusion: </strong>The consumption of ONS in addition to dietary counseling, in patients with early-stage breast cancer undergoing anthracycline-based chemotherapy, is associated with an increase in final body weight at 12 weeks compared to baseline body weight. ONS is also associated with less significant weight loss and a slower deterioration of nutritional status in patients during chemotherapy in the short term. ONS should be considered to incorporate into dietary counseling for patients with early-stage breast cancer receiving an anthracycline-based regimen, especially for those at risk of malnutrition, such as those with low baseline body weight, or loss of appetite.</p><p><strong>Trial registration: </strong>Clinical trial registration number: NCT06311357 . Date: 13 March 2024.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"299"},"PeriodicalIF":2.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When tomorrow starts without me.","authors":"Ali Alkan, Aslı Alkan, Özgür Tanrıverdi","doi":"10.1007/s00520-025-09351-7","DOIUrl":"https://doi.org/10.1007/s00520-025-09351-7","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"300"},"PeriodicalIF":2.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of distinct fatigue trajectories in patients with nasopharyngeal carcinoma undergoing radiotherapy: an observational longitudinal study.","authors":"Jieling Wu, Xinru Yang, Qiqi He, Zhiying Zhan, Zilan Wu, Litao Zhuo, Li Su, Wenlong Lyu, Jinru Ye, Xiurong Song, Jinsheng Hong, Jihong Song","doi":"10.1007/s00520-025-09322-y","DOIUrl":"10.1007/s00520-025-09322-y","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the fatigue trajectory types and various influencing factors during intensity-modulated radiotherapy (IMRT) in patients with nasopharyngeal carcinoma (NPC).</p><p><strong>Methods: </strong>Longitudinal data of cancer-related fatigue from 182 participants with NPC were assessed at baseline (T0) and weekly (T1-T7) during radiotherapy via the revised Piper Fatigue Scale. Patient-generated data from the Subjective Global Assessment (PG-SGA) and the Hospital Anxiety and Depression Scale were collected at baseline. Latent growth curve models (LGCM) and latent class growth models (LCGM) were used to explore fatigue trajectories and heterogeneity among fatigue trajectories, respectively. The influencing factors of different trajectories were assessed via multivariate logistic regression analysis.</p><p><strong>Results: </strong>The overall fatigue level during IMRT tended to increase but then decreased, as indicated by the LGCM results (S = 0.985, P < 0.001), and peaked in the fifth week. The LCGM results fit the following three fatigue trajectories: \"mild fatigue persistence\" (n = 54, 29.7%), \"mild fatigue growth\" (n = 95, 52.2%), and \"moderate fatigue persistence\" (n = 33, 18.1%). PG-SGA score and being married were risk factors for the \"mild fatigue growth\" group. The risk factors for the \"moderate fatigue persistence\" group were PG-SGA, anxiety, and being married, whereas a family income < 3000 Y/month was a protective factor.</p><p><strong>Conclusions: </strong>Three types of fatigue trajectories are observed during IMRT in patients with NPC. PG-SGA score, marital status, anxiety, and family income may influence the type of fatigue trajectory in patients, so preventive measures should be taken on the basis of specific circumstances.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"298"},"PeriodicalIF":2.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment and monitoring by Integrated Palliative care Outcome Scale: an observational study on cancer patients at home.","authors":"Rita Ostan, Giuseppe Gambino, Luca Franchini, Gianpaolo Neri, Italo Malavasi, Daniele Roganti, Raffaella Pannuti, Simone Veronese, Guido Biasco, Silvia Varani","doi":"10.1007/s00520-025-09363-3","DOIUrl":"https://doi.org/10.1007/s00520-025-09363-3","url":null,"abstract":"<p><strong>Purpose: </strong>Integrated Palliative care Outcome Scale (IPOS) is a specific tool for assessing needs in palliative care, recording and monitoring physical symptoms, emotional concerns, and communication and practical issues. This study aimed to evaluate if the IPOS tool was able to assess the impact of at-home palliative care program on physical symptoms and psychosocial problems in advanced cancer patients.</p><p><strong>Methods: </strong>This observational prospective longitudinal mixed-method study included advanced cancer patients assisted at home. IPOS questionnaire (patient version-7-day recall) was administered at the entry, after 2 and 4 weeks. A qualitative thematic analysis (TA) of the first open-ended question was performed. Change over time in IPOS scores was analyzed by Friedman's test for repeated measures.</p><p><strong>Results: </strong>Among the 60 patients included (29 men, 31 women; 68.2 ± 14.0 years), 47 completed the 4-week observation period. TA indicated that the 3 main themes running through the three surveys (at the entry, day 14, and day 28) relate patients' concerns about symptoms and side effects of treatments, family members, the evolution of the disease, and the daily issues. Repeated measures test demonstrated that patients entering with medium-high IPOS total score (n = 27) showed a significant decrease in IPOS total score (p = 0.003), physical symptoms (p = 0.002), and communication and practice (p = 0.028) subscales after 2 and 4 weeks.</p><p><strong>Conclusion: </strong>Patients entering in home care with higher burden of symptoms and psychosocial problems reported significant decrease in IPOS scores. In these patients, IPOS was responsive to change showing substantial clinical improvements after the activation of home assistance.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"301"},"PeriodicalIF":2.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interdependence relationships between unmet supportive care needs and its influencing factors in couples coping with colorectal cancer: a cross-sectional study.","authors":"Xiaoke Qiu, Jiayu Mao, Can Wang, Xueli Yang, Jie Zhao, Qiuping Li","doi":"10.1007/s00520-025-09350-8","DOIUrl":"https://doi.org/10.1007/s00520-025-09350-8","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the unmet supportive care needs (USCNs) in colorectal cancer survivors and their spousal caregivers and identifying factors influencing USCNs from a dyadic perspective.</p><p><strong>Methods: </strong>In this cross-sectional survey, a total of 343 dyads consisting of Chinese colorectal cancer survivors and their spousal caregivers were recruited from a dyadic perspective. This study evaluated participants' USCNs, psychological distress of anxiety and depression, and benefit finding. The Actor-Partner Interdependence Mediation Model (APIMeM) as data analysis approaches was used to capture the bidirectional and mediating effects between the variables, revealing key factors influencing USCNs in colorectal cancer couples.</p><p><strong>Results: </strong>A total of 343 colorectal cancer couples were surveyed, reporting different USCNs. The analysis revealed that psychological distress and benefit finding play a central role in influencing USCNs. These factors affect the dyadic health outcomes of both cancer survivors and their spousal caregivers through bidirectional relationships. Specifically, psychological distress influences USCNs through its impact on benefit finding, which mediates the relationship between psychological distress and unmet care needs in the dyads.</p><p><strong>Conclusions: </strong>This study highlights the USCNs and its influencing factors within colorectal cancer couples. The APIMeM findings suggest that USCNs can be enhanced by reducing psychological distress and strengthening the protective role of benefit finding. In response to the unique needs of colorectal cancer couples, tailored psycho-social supportive care interventions should be developed, focusing on alleviating psychological distress and reinforcing the positive aspects of benefit finding, thereby fostering stronger bi-directional relationships and improving USCNs in this population.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"297"},"PeriodicalIF":2.8,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring financial toxicity and its impact on health-related quality of life of cancer patients.","authors":"Wajiha Ahmad, Shahid Muhammad Iqbal, QurratulAin Jamil","doi":"10.1007/s00520-025-09357-1","DOIUrl":"https://doi.org/10.1007/s00520-025-09357-1","url":null,"abstract":"<p><strong>Aim: </strong>This study evaluates financial toxicity (FT), its risk factors and assesses its relationship with health-related quality of life (HRQOL) in cancer patients in Bahawalpur, Pakistan.</p><p><strong>Method: </strong>This was a cross-sectional study of cancer patients undergoing treatment in two public hospitals. It assessed FT with a Comprehensive Score for Financial Toxicity (COST) and HRQOL with a functional assessment of cancer therapy: general (FACT-G). A questionnaire was also utilised to collect and analyse data. We conducted a linear regression analysis to identify risk factors for FT and Pearson correlation to evaluate the association between FT and HRQOL.</p><p><strong>Results: </strong>The study included 336 patients between March and June 2024. The majority of the patients were female and from rural areas. The mean COST score was 7.21 (2-12), and the mean FACT-G score was 28.60 (22-37). There was a strong positive relationship between the COST and FACT-G scores, indicated by a correlation coefficient of 0.84 (P < 0.001). Furthermore, the study observed that the COST score was a reliable predictor of the FACT-G score. Multivariate linear regression analysis found cancer type (β =  - 0.346; 95% CI, - 0.588 to - 0.103; P < 0.05), residence (β =  - 0.494; 95% CI, - 1.005 to 0.017; P < 0.05), and distance between home and healthcare facility (β =  - 0.340; 95% CI, - 0.607 to - 0.073; P < 0.05) as risk factors of the FT.</p><p><strong>Conclusions: </strong>Our findings indicate high FT, underscoring the critical need for strategies to reduce the growing FT among cancer patients in Pakistan. Moreover, the significant relationship between FT and HRQOL needs further studies to explore potential causal factors.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"294"},"PeriodicalIF":2.8,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}