Asif Ali, H. Tahir, Barira Shafiq, Urooj Afzal Chughtai, Z. Khan, Z. Ashraf, Mawra Arif, Komal Razzaq, Bisma Arshad
{"title":"Biologically Active Compounds and Use of Medicinal Plants in Treatment of Microbial Infections, Sources, Biological Action and Cellular Action","authors":"Asif Ali, H. Tahir, Barira Shafiq, Urooj Afzal Chughtai, Z. Khan, Z. Ashraf, Mawra Arif, Komal Razzaq, Bisma Arshad","doi":"10.36348/sjls.2022.v07i02.007","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.007","url":null,"abstract":"Medicinal plants have been used with practical implementation of certain herbal great source of plant based flavonoids, antioxidants compounds. Medicinal plants were traditionally used for health care and serve as the bases for the emergence of modern medicine. They have possess the high quality of the extracts to evaluate their therapeutic efficacy for their pharmacological action. Large variety of medicinal plants have been used as aromatic purposes and hence valuate for aroma and pharmacological sectors. Medicinal plants snowed stronger binding to the proteins secreted by the parasitic worms thus inhibiting them to proliferate in the cellular tissues thus acting as main source of immunity booster to the living tissues against the dyspepsia, gastritis, hyperacidity, menorrhagia, diabetes. Saraca asoca also used as source of medicinal pant due to its to antibacterial activity because of its potential against the of multiple bacterial strains. Some of the medicinal plants acting as dual nature such as targeting the microbial proteins and peptides playing important role in the development of natural therapies. Nanoparticles based therapies can be utilized for treatment of infectious diseases.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124344922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Zahra, Slaoui Aziz, Benaouicha Nisrine, Zraidi Najia, Lakhder Amina, Baydada Aziz
{"title":"Prenatal Diagnosis and Pregnancy Management of MMC","authors":"L. Zahra, Slaoui Aziz, Benaouicha Nisrine, Zraidi Najia, Lakhder Amina, Baydada Aziz","doi":"10.36348/sjls.2022.v07i02.009","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.009","url":null,"abstract":"Open spina bifida (myelomeningocele) is a specific kind of neural tube defect (NTD) resulting from a trouble of closure of the caudal region of the neural tube early in embryogenesis. The diagnosis and management of open spina bifida has changed significantly over the past century. Significant advances in the prevention, diagnosis and treatment of open spina bifida have been made over the last years. The most significant strategy for the prevention of open spina bifida has been with folic acid supplementation. Although progress in the field of myelomeningocele diagnosis and treatment has revolutionised the medical treatment of open spina bifida, the postnatal treatment of myelomeningocele evolved significantly and is now complicated by issues surrounding prenatal diagnosis, including availability, economic feasibility, and selection for invasive fetal surgery and management of pregnancy.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131176573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Awan, K. Mehmood, Asif Ali, H. Tahir, I. Ali, Saba Malik, Amjad Ali, Muhammad Sheeraz Javed, Muhammad Faraz Ali
{"title":"Increase Potential of Environmental Stresses and Climatic Risk of Heavy Metals in Plants and Control through Nanotechnology Advances","authors":"B. Awan, K. Mehmood, Asif Ali, H. Tahir, I. Ali, Saba Malik, Amjad Ali, Muhammad Sheeraz Javed, Muhammad Faraz Ali","doi":"10.36348/sjls.2022.v07i02.005","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.005","url":null,"abstract":"Different heavy salts accumulated in the soil causing the soil salinity and damage the biological processing occurring in plants such as photosynthesis and light reactions. Climate changes also promote the accumulation of heavy metals by promoting the chemicals substances in the leaves and roots cells that causing the chlorosis. Coal combustion release the large amount of mercury metals that acting as toxic for the plants. There is need to design the biological and mechanical processing the removal of salts and toxic wastes from surfaces in such a way that no eruptions of plant materials occur at the surfaces. Nanotechnology employed the nanoparticles to capture the toxic metals through biological and chemical process that is more reliable and less expensive. A large variety of nanoparticles in the form of nanobased graphene oxides, graphite oxides and CNT, mesoporous silica materials have been used for controlling the pollution caused by heavy metals. These nanoparticles are compatible for the plant growth by suppressing the crop diseases by acting directly on phytopathogens. Therefore, it is reliable for controlling the risk of environmental pollution caused by heavy metals.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134165837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Tahir, Hafiz Naeem Ul Rehman, Fareeha Nasrullah, K. Mehmood, U. Chaudhry, Zoha Ashraf, R. Abbasi, Asma Mehboob
{"title":"New Insights and Biological Role in Agricultural Based Development of Novel Crops through Nanotechnology and Biotechnological Advances for Gene Modification","authors":"H. Tahir, Hafiz Naeem Ul Rehman, Fareeha Nasrullah, K. Mehmood, U. Chaudhry, Zoha Ashraf, R. Abbasi, Asma Mehboob","doi":"10.36348/sjls.2022.v07i02.006","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.006","url":null,"abstract":"Seed germination is the critical stage in plant's life cycle, assisting sapling development, survivorship, and population trends. Plants, as sessile life forms, are easily exposed to abiotic stresses like heat, salinity, cold, soil alkalinization, drought. The interaction of nano-materials with the plant, soil, and the holobiont systems is critical for understanding their behaviors within every complicated ecosystem. The use of nanoparticles has a beneficial impact on germinating seeds and also plant growth and development. Titanium based nanoparticles triggers the development of carbohydrates, which promotes rates of photosynthesis and plant growth. It is hoped that nanotech will provide long-term remedies by replacing conventional bulk fertilizers with nano-particulate counter parts that have excellent characteristics for overcoming current problems such as mineral bio-availability and absorption. Nano-priming could be practiced to seeds to preserve them during storage, enhance germination rate, germination synchronization, and plant growth, and also enhance resistance of crop to biotic and abiotic stressful conditions.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125195117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Mikailu, Nimifaa Lucy Obomate, Okitche Princewill Ugochukwu, I. Ekenna
{"title":"Anti-Inflammatory, Fibrinolytic and Anti-Oxidant Activities of the N-Hexane Extract of Ficus sur Forssk (Moraceae) Leaves","authors":"S. Mikailu, Nimifaa Lucy Obomate, Okitche Princewill Ugochukwu, I. Ekenna","doi":"10.36348/sjls.2022.v07i02.004","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.004","url":null,"abstract":"This study investigates the anti-inflammatory, fibrinolytic and anti-oxidant activities of the n-hexane extract and fractions of Ficus sur Forssk leaves. The extract was separated on column chromatography using a gradient elution of hexane, dichloromethane and ethanol. Pooled column fractions were assayed for membrane stabilizing for anti-inflammatory, Streptokinase inhibition for fibrinolytic and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) reduction for anti-oxidant activity. Column fractions were pooled into five fractions (F1 – F5). The n-hexane crude extract and the fraction F3 consistently exhibited anti-inflammatory and fibrinolytic ability. The leaf extract of F. sur showed negligible anti-oxidant activity. Except for F1 all the fractions and the crude extract showed very high dose-dependent anti-inflammatory property even significantly higher (p <0.05) than the reference drug – diclofenac. Crude extract, F2 and F3 exhibited fibrinolytic ability. F1 showed the lowest assayed biological activity consistently. The study shows that the column fractions of n-hexane extract of F. sur leaves have fibrinolytic and anti-inflammatory activity and can be used in the management of thrombosis and inflammation.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115238231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sadaqat S. Ali, Rabia Nadeem, Bisma Arshad, H. Makki, Asma Atta, K. Fiaz, Komal Razzaq, M. Adil, Muhammad Sheeraz Javed
{"title":"New Insights in Cropping Patterns, Hydroponic Farming System and Roles in Crop Optimization through Advanced Technologies","authors":"Sadaqat S. Ali, Rabia Nadeem, Bisma Arshad, H. Makki, Asma Atta, K. Fiaz, Komal Razzaq, M. Adil, Muhammad Sheeraz Javed","doi":"10.36348/sjls.2022.v07i02.003","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.003","url":null,"abstract":"Cropping pattern reflects the growing of genetically modified crops and ordinary crops in the different conditions of temperature and pH also affected the cultivation. It also advances the soil agro ecological measurement and climatic conditions. Monocropping patterns increase the mass crop production due to higher yields by controlling the attack of different pests and improving the soil microbe diversity. Crop rotation depends on different factors such as rotating series and applied frequency of certain crops that improved the functional properties of microorganisms growth. This approach can be helpful for targeting the soil-borne pathogens to maximize soil benefits. Proper irrigation system also another agricultural approach for enriching the ecosystem. It enables the original crop to strike again after harvesting and to raise another crop. Plants grown in in the hydroponic system shows high growth as compared to the conventionally field-grown plants also increase the chances of sustainable agricultural development through green technology where large number of plants can be grown in the nutrient medium. Cropping patterns to make farming more efficient that can be helpful to irrigate crops and more disease resistant varieties.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124758906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Javed, Muhammad Bilal Shahid, Humaira Naeem, Ameer Hamza Jam, A. Nawaz, Aqsa Nazeer
{"title":"Aflatoxins Poisoning","authors":"A. Javed, Muhammad Bilal Shahid, Humaira Naeem, Ameer Hamza Jam, A. Nawaz, Aqsa Nazeer","doi":"10.36348/sjls.2022.v07i02.002","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.002","url":null,"abstract":"Aflatoxins are released from Aspergillus species and enter in living organisms from various routes and results in toxicity. Humans are exposed to aflatoxins poisoning due to consumptions of infected crops, meat, poultry and dairy produce. The physiological effects due to aflatoxins may be mild to fatal, according to their exposed concentration to humans and bioabsorption duration. These side effects are usually categorized as acute toxicity, genotoxicity and immunotoxicity. So further, efficient genomic and proteomic strategies s are required to develop resistant livestock breeds and dietary significance having cultivars along with general public awareness campaigns related to aflatoxins contamination free edible items selection.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121350485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Javed, S. Aslam, Zubaida Qayyum, A. Fatima, Anam Sadiq, K. Kubra
{"title":"Changing Trends of Solanum nigrum Based Pharmacognosy","authors":"A. Javed, S. Aslam, Zubaida Qayyum, A. Fatima, Anam Sadiq, K. Kubra","doi":"10.36348/sjls.2022.v07i02.001","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.001","url":null,"abstract":"Solanum nigrum is one of the commonly found herb around the globe and contains diverse therapeutic along with biological control based potentials. For last few decades, not only aqueous but also other organic solvents based extract have been prepared to obtain maximum benefits of its components to recover external and internal wounds, inflammations, infections, cancer and to control many disorders like cytotoxicity, cardiovascular, hepatic, gastric and enzymatic complications. Moreover, it has been found as effective to reducer aging and an ideal local cost source of phytoremediation. For future progress, its dose and shots optimization should be focused by researchers.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"124 19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114139443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghazanfar Ali, N. Akhter, R. Akram, S. A. J. Kazmi, Mahwash Saleem Khan, S. Iqbal
{"title":"The Loss of Smell and Taste in the COVID-19 Outbreak, A Cross Sectional Study","authors":"Ghazanfar Ali, N. Akhter, R. Akram, S. A. J. Kazmi, Mahwash Saleem Khan, S. Iqbal","doi":"10.36348/sjls.2022.v07i01.005","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i01.005","url":null,"abstract":"Background: A significant proportion of people infected with COVID-19 report new onset of smell and taste loss. The duration of the chemosensory impairment and prognostic factors of recovery is still unclear. We aimed to investigate the prevalence rate and other signs and symptoms which are predictors in patients. Objective: To find out the association of Anosmia and Ageusia with COVID-19. To find out relationship of Gender with Anosmia and Ageusia in COVID-19 or other URTI. Methods: I was a cross-sectional study, participants were from CMH, Multan, Hospitals of different cities of the province of Punjab, Pakistan. The study was conducted from 1st July to 31st of August 2021. 185. All faculty members and medical Students of CMH Bahawalpur. Results: Out of 185 participants, 99 (53.5%) were male and 86 (46.5%) were female. The mean age was 23.93 ± 6.661years. Pearson correlation of covid-19 with loss of smell is 0.533 which shows that there is strong positive relationship between them. On one-way ANOVA fever sig. is 0.002 which shows high significance. URTI also shows association but other signs and symptoms like dyspnoea, dry cough do not show any significance. Shows the majority of participants are suffering from taste and smell loss (95.1%) along with body aches (82.7%), dyspnoea (94.6%), acute dry cough (36.2%), URTI (19.5%) and fever (36.2%).","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122578097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ali, Zarghoona Naz, B. Kanwal, Syeda Ayesha Hamdani, Rabia Rahmat, H. Tahir, Summan Summan, Salma Sharif
{"title":"Botanical Role, Sources, Bioactive Compounds in Medicinal and Genetically Modified Crops","authors":"E. Ali, Zarghoona Naz, B. Kanwal, Syeda Ayesha Hamdani, Rabia Rahmat, H. Tahir, Summan Summan, Salma Sharif","doi":"10.36348/sjls.2022.v07i01.004","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i01.004","url":null,"abstract":"The chemical compounds extracted from medicinal plants have potential to evoke mental and social sensations in addition to maintain physical health. . Species of Asteraceae and Liliaceae play significant cardiovascular roles irrespective of exploring their toxicological aspects. Carbohydrates, proteins, lipids, nucleotides, fats, and steroids are the primary organic compounds which are involved in metabolism of essential developmental and growth functions of plants. The detrimental effects of environmental stress factors are suppressed by the gene expressions of ion transporters and water channel proteins present in the cell membranes incorporated with the up or downregulation of osmo-proctant osmolytes and essential proteins such as HSP and chaperones. Sunflower (Helianthus annuus L.) is an important crop known for its food, forage, and silage constituents. It is a prominent specie in Asteraceae family. Its seeds are enriched with edible oil-world’s fourth largest oil source. The mineral elements, dietary fibers, and secondary metabolites such as carotenoids, flavonoids, tocopherols, saponins, tannins, alkaloids, chlorogenic acid, caffeic acid, peptides, phytosterols, triterpene glycosides, and vitamins contribute towards nutraceutical roles. Pot marigold (Calendula officinalis) possesses antibiotic, anti-inflammatory, and antifungal properties which allow its applications in preventing muscle spasms, treating sore throat and ulcers of duodenum and stomach, soothing eczema, healing wounds, and relieving rashes.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"36 11-12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120900545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}