Haya: The Saudi Journal of Life Sciences最新文献

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Estimation of Fertility Status of Coastal Soils for Agricultural Planning in Bangladesh 孟加拉国沿海土壤肥力状况的农业规划评估
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-05-15 DOI: 10.36348/sjls.2022.v07i05.001
Md Shahin Hossin, A. Paul, Md Fazlul Hoque, M. Mukta, Md. Delower Hossain
{"title":"Estimation of Fertility Status of Coastal Soils for Agricultural Planning in Bangladesh","authors":"Md Shahin Hossin, A. Paul, Md Fazlul Hoque, M. Mukta, Md. Delower Hossain","doi":"10.36348/sjls.2022.v07i05.001","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i05.001","url":null,"abstract":"A study was conducted to know the fertility status of coastal soils of Bangladesh for agricultural planning. Thirty composite soil samples were collected from different locations of Kalapara upazila under Patuakhali coastal district in Bangladesh with Geographic Positioning System (GPS) positions. The soil samples were analyzed for physical properties (moisture, texture, bulk density, particle density and porosity) and chemical properties (pH, electrical conductivity, total nitrogen, organic carbon, exchangeable sodium, exchangeable potassium, available sulphur and available phosphorus). The range of moisture contents of collected soils was 24 to 29% and the textural class was silty clay. The bulk density ranged from 1.30 to 1.47 gcm-3. The particle density ranged from 2.31 to 2.49 gcm-3. The porosity of soil samples ranging from 40.96 to 46.06%. The pH ranged from 5.85 to 6.45. The EC value of collected soils ranged from 3.10 to 5.12 dSm-1. The total nitrogen and organic carbon content was low to medium. The exchangeable sodium and potassium content of soils ranged from 9.22 to 18.47 meq 100g-1 and 0.16 to 0.27 meq 100g-1, respectively. The available sulphur and phosphorus content of soils ranged from 17.21 to 33.21 mg kg-1 and 17.12 to 33.09 mg kg-1, respectively. The results revealed that the soils of the study area were slightly to moderately saline and thus the nutrients present in the soils were low to medium level. Hence, salinity problem of soils should be considered before agricultural planning in the study area.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129639421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Borneol as Adjuvant Chemotherapy: A New Way for the Development of Novel Chemotherapeutic 冰片作为辅助化疗:开发新型化疗药物的新途径
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-04-23 DOI: 10.36348/sjls.2022.v07i04.002
Irum Naureen, A. Saleem, Muhammad Kashif Aziz, Ameer Hamza Jam, U. Baneen, Arfa Chaudhary, Saima Munir, Iqbal Ahmed
{"title":"Borneol as Adjuvant Chemotherapy: A New Way for the Development of Novel Chemotherapeutic","authors":"Irum Naureen, A. Saleem, Muhammad Kashif Aziz, Ameer Hamza Jam, U. Baneen, Arfa Chaudhary, Saima Munir, Iqbal Ahmed","doi":"10.36348/sjls.2022.v07i04.002","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i04.002","url":null,"abstract":"Nature has generously open life-saving remedies to mankind by offering evolutionarily optimized drug like bimolecular in the form of several natural products. These marvelous gifts of nature have been serving as most suitable candidates against the treatment of multiple disorders and particularly for cancer (2nd leading cause of death, cancer) due to their pleiotropic mode of action on target molecules. Current review intends to provide an update on the bioactivities of such gifts from nature, natural borneol, which is the major bioactive constituents of traditionally used medicines. Borneol is a monoterpenoid, isolated from different medicinal plants and have strong potential to be used against multiple disorders such as bacterial and inflammatory infections. Recently it is investigated that borneol has a great potential of inhibiting the growth of multiple neoplasms such as hepatocellular carcinoma, neuroblastoma, glioma, esophageal squamous cell carcinoma, ovarian and lung cancer. Moreover, by regulating the BBB junctions it also increases the drug concentration in cancer cells, this shows that its combine use with already practiced therapeutics may increase the efficacy of these therapeutics against cancer cells. In this review we will summarize all the studies on anticancer activity of borneol, our primary goal will be to discuss the combined use of borneol with other clinically used drugs to improve their efficacy against human cancers.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122988147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbial Assisted Bioremediation of Polluted Water 微生物辅助污水的生物修复
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-04-13 DOI: 10.36348/sjls.2022.v07i04.001
A. Saleem, Irum Naureen, Gulnaz Tasleem, Rabia Anwar, Mahnoor Mairaj, Huma Muddassar, N. Rana
{"title":"Microbial Assisted Bioremediation of Polluted Water","authors":"A. Saleem, Irum Naureen, Gulnaz Tasleem, Rabia Anwar, Mahnoor Mairaj, Huma Muddassar, N. Rana","doi":"10.36348/sjls.2022.v07i04.001","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i04.001","url":null,"abstract":"Bioremediation is a process to remove or detoxify contaminant present in the environment by certain biomolecules or biomass to bind and concentrate selected ions or other molecules. Water pollution is an issue of great concern worldwide, and it can be broadly divided into three main categories, that is, contamination by organic compounds, inorganic compounds (e.g., heavy metals), and microorganisms. A wide range of microorganisms, including bacteria, fungi, yeasts, and algae, can act as biologically active methylators, which are able to at least modify toxic species. Microorganisms cannot destroy metals, they can alter their chemical properties via a surprising array of mechanisms. Different factors affect bioremediation include environmental factor biological factor, availability of nutrients, temperature, ph, and toxic compounds. Among organic pollutants, hydrocarbons may enter in water either directly by spills or effluents or indirectly from atmosphere. These metals are extremely sensitive at low concentrations and can be stored in food webs, posing a serious public health risk. Several microorganisms (natural/exotic/ engineered) having specific metabolic capability and various enzyme production ability which fall under six main divisions include Oxidoreductases, Transferases, Hydrolases, Lyases, Isomerases and Ligases (synthetases) are used during bioremediation process. The heavy metals associated with environmental contamination, for instance, lead (Pb), cadmium (Cd), and chromium (Cr), which are potentially hazardous to ecosystems. The types of microorganisms that are used in bioremediation processes due to their natural capacity to biosorb toxic heavy metal ions.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130616701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Potential Health Benefit of Dates Based on Human Intervention Studies: A Brief Overview 基于人为干预研究的枣的潜在健康益处:简要概述
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-03-25 DOI: 10.36348/sjls.2022.v07i03.006
Irum Naureen, A. Saleem, N. Rana, Maham Ghafoor, Farwa Muhammad Ali, Naveed Murad
{"title":"Potential Health Benefit of Dates Based on Human Intervention Studies: A Brief Overview","authors":"Irum Naureen, A. Saleem, N. Rana, Maham Ghafoor, Farwa Muhammad Ali, Naveed Murad","doi":"10.36348/sjls.2022.v07i03.006","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i03.006","url":null,"abstract":"Date palm tree (Phoenix dactylifera L.) is an important crop or khajoor in the local language which is cultivated in many countries. Different types of dates are present but Ajwa khajoor is very beneficial in cardiovascular activity, heart disease, antimicrobial, nephroprotective, antioxidant, anti-inflammatory activity, provide relaxation during pregnancy, reduce risk of tooth decay, improve bone health, and also provide mental clarity. Prophet Muhammad (Peace Be upon Him) said that the best assets are date palm, dates cure several disorders, and he suggested Muslims to eat the date and have a tendency the date palm. Dates play key role in anti-cancer activity, anti-tumor, cardio-protective activity, and neuroprotective activity. Dates fruits and seeds are considered essential nutrients and medicines. They can be used in a variety of cosmetic and beauty products. Many cosmetic products contain high levels of chemical compounds, commonly found in synthetics such as hydroquinone. Date seed oil has been shown to have a positive effect on human skin and hair, as well as a few products (body creams, soaps, hair products, and sunscreens) are sold. Seed oils have high oxidative properties, extended storage capacity, and can protect the skin from UV rays and repair it. Bioactive compounds, such as flavonoids and phenolics, can prevent hair loss and promote hair growth. The extracts from dietary seeds are rich in phytosterols, essential fatty acids, and nutrients needed to maintain healthy scalp, promote normal hair growth, and support nourishing functions of sebaceous glands and hair follicles. It is important to all synthetic skincare products and medically very beneficial.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125401343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Nanotechnology and biological advances, novel tools for plant genetics and physiological role of newly crops and limited factors affecting growth 纳米技术和生物学的进展,植物遗传学的新工具和新作物的生理作用以及影响生长的有限因素
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-03-22 DOI: 10.36348/sjls.2022.v07i03.005
Nadia Mubarik, M. Irshad, M. Aslam, Anum Marwat, R. Robina, Sobiya Mohiuddin Omar, Arsalan Arif, Muhammad Sohaib, Asma Mehboob
{"title":"Nanotechnology and biological advances, novel tools for plant genetics and physiological role of newly crops and limited factors affecting growth","authors":"Nadia Mubarik, M. Irshad, M. Aslam, Anum Marwat, R. Robina, Sobiya Mohiuddin Omar, Arsalan Arif, Muhammad Sohaib, Asma Mehboob","doi":"10.36348/sjls.2022.v07i03.005","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i03.005","url":null,"abstract":"Nano-pesticides are essential for the successful and sustainable management of different pests, and they can decrease the use of agrochemicals, thereby mitigating current environmental dangers. Nevertheless, advancements in nano-particles or micro-particles, as well as distribution models for biolistic gene delivery in various plants, are still needed to enhance grain growth and crop and plant protection. , seed priming is being used effectively to expedite and synchronize germination, increase seedling vigor, and make plants extra resilient to various biotic and abiotic stresses, resulting in increased efficiency and quality of food. Nano fertilizers have distinct properties like mega absorption, increase in production, enhanced activity of photosynthesis, and a substantial improvement in leaf surface area. Growth of plants is changed to a particular environment conditions at different phases of development; and hence, a proper choice of planting date increases photosynthesis efficacy. In this perspective, providing carbon nano-tubes in to the chloroplasts has resulted in a progress for plants' enhanced capacity to collect more energy from the sun. Lower rates of photosynthetic activity in the crop plants under the cold stress limited metabolic pathways for Carbon assimilation.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"289 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121222507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green Synthesis of Silver Nanoparticles Using the Plant Extract of Leucas aspera (Willd) Link and their Characterization 绿色合成纳米银的植物提取物及其表征
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-03-16 DOI: 10.36348/sjls.2022.v07i03.003
V. Smitha, M. Priyadharshana, M. Girija, M. A. Badhsheeba, V. Vadivel
{"title":"Green Synthesis of Silver Nanoparticles Using the Plant Extract of Leucas aspera (Willd) Link and their Characterization","authors":"V. Smitha, M. Priyadharshana, M. Girija, M. A. Badhsheeba, V. Vadivel","doi":"10.36348/sjls.2022.v07i03.003","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i03.003","url":null,"abstract":"Objective: Silver nanoparticles (AgNPs) were synthesized through the high-efficient, cost-effective green and facile process, using the Leucas aspera (Willd.) Link extract as a bio-reduction and capping agent at room temperature. Methods: The greenly synthesized AgNPs were subjected to UV-Visible spectrophotometer, Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction spectroscopy (XRD) analyses. Results: The surface plasmon resonance found at 410 nm confirmed the formation of AgNPs. FTIR analysis was carried out to identify possible biomolecules responsible for the bio-reduction of silver ions. Furthermore, the crystallographic structure was confirmed by XRD and the average particle size of the synthesized silver nanoparticles was calculated which was found to be 36 nm. Conclusion: This study exhibits one step innovative green approach for the synthesis of silver nanoparticles from L. aspera plant extract. The method stands out primarily because it is eco-friendly and advantageous over conventional physical and chemical methods.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114117878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential Impact of Smog on Human Health 雾霾对人体健康的潜在影响
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-03-16 DOI: 10.36348/sjls.2022.v07i03.002
Irum Naureen, A. Saleem, S. Aslam, Laiba Zakir, Aima Mukhtar, Rafia Nazir, Seemab Zulqarnain
{"title":"Potential Impact of Smog on Human Health","authors":"Irum Naureen, A. Saleem, S. Aslam, Laiba Zakir, Aima Mukhtar, Rafia Nazir, Seemab Zulqarnain","doi":"10.36348/sjls.2022.v07i03.002","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i03.002","url":null,"abstract":"Smog is a term used to describe pollution suspended in humid air. It's made up of different- sized dust particles, as well as non-metal oxides, organic compounds, and heavy metals. Apart from smoking cigarettes, one of the changeable variables leading to the development of respiratory diseases is exposure to toxic compounds dispersed in the air. . Smog is a visible form of air pollution that arises due to the over-emissions of some primary pollutants like volatile organic compounds (VOCs), hydrocarbons, SO, NO, and NO2 which further react in the atmosphere and give rise to toxic and carcinogenic secondary smog components. There are six categories of airborne chemicals that have a negative impact on public health and cause disease. Ozone, particulate matter (PM) of various dimensions - PM2.5, PM2.5–10, PM10, nitrogen – all has important implications. Lead, carbon dioxide, Sulphur dioxide, and carbon monoxide Small dust particles (PM10 and PM2.5) are given special attention since they can enter the lower respiratory tract. The page examines the impact of atmospheric pollutants on both the development and exacerbation of the disease, in addition to detailing the composition of smog and sources of air pollution. Asthma, chronic obstructive pulmonary disease, respiratory infections, and other respiratory tract illnesses can all cause symptoms. Lung cancer is a type of cancer that affects. Some of the legislative methods used in various nations to reduce exposure to harmful air pollution are presented.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127728162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Epidemiological Aspect and Antibiotic Resistance Profile of Acinetobacter baumannii in the Resuscitation Department of Ibn Tofail Hospital CHU Med V 伊本托菲尔医院复苏科鲍曼不动杆菌流行病学及耐药性分析[j]
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-03-05 DOI: 10.36348/sjls.2022.v07i03.001
R. Rada, R. Nakhli, S. Khayati, L. A. Said, K. Zahlane
{"title":"Epidemiological Aspect and Antibiotic Resistance Profile of Acinetobacter baumannii in the Resuscitation Department of Ibn Tofail Hospital CHU Med V","authors":"R. Rada, R. Nakhli, S. Khayati, L. A. Said, K. Zahlane","doi":"10.36348/sjls.2022.v07i03.001","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i03.001","url":null,"abstract":"Background: Multidrug resistant Acinetobacter baumannii, (MRAB) is an important cause of hospital acquired infection. The purpose of this study is to evaluate the epidemiology and analyze the level of antibiotic resistance of Ab strains in the intensive care unit of the ibn Tofail Hospital of the Mohammed VI University Hospital of Marrakech. Material and method: This study is a retrospective review of a city hospital epidemiology data base and includes 42 isolates of Acinetobacter baumannii (AB) from 120 patients. The antibiogram was performed according to European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommendations. Results: In our study, all bacteriological samples were taken from the intensive care unit. The mean age was 48.2 years with extremes ranging from 19 to 72 years.88 patients were male (73.4% of all cases) and 32 female (26.6%).The most frequent reason for hospitalization in the intensive care unit was severe head trauma in 35 cases (29%).During the study period, out of 120 samples received, 42 Ab strains were isolated (35% of samples). These strains were mainly isolated from blood cultures (40%). Conclusions: The diffusion of multi-resistant Ab strains in intensive care units seems to be alarming, hence the need to implement an effective strategy to fight nosocomial infections.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129624824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Season Year Milk Production in Different Breeds of Dairy Cows in Badghis Province 巴德斯省不同品种奶牛季-年产奶量的影响
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-03-02 DOI: 10.36348/sjls.2022.v07i03.004
A. Azimi, S. Anwari, Mohmmad-Mhadi- Moheghi
{"title":"Effect of Season Year Milk Production in Different Breeds of Dairy Cows in Badghis Province","authors":"A. Azimi, S. Anwari, Mohmmad-Mhadi- Moheghi","doi":"10.36348/sjls.2022.v07i03.004","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i03.004","url":null,"abstract":"The experiment was conducted on three breeds the total 30 breeds of dairy cows and the number of animal of different breeds was 10 holistan, 10 garai and 10 Cross-bred (CB) during 2019 and 2020. The objective of this study was to know the impact of seasonal on milk production performance of Holistan, Garsi and CB or doragh. The average highest seasonal milk production of Garsi and CB was in spring and summer season, 9.22 and 9.02 liter, respectively and Holistan was highest in spring and summer season (8.261 liter), respectively. The overall average milk production of CB, Holistan and Garsi were 8.86, 7.98 and 7.37 respectively. The seasonal variation and milk production performance of all three breeds were found highly significant. Because the other season production was low. The average milk production of 2470 ± 37 L milk production in spring season followed by 2427 ± 41 L in summer and lowest in winter, as 2403 ± 82 L respectively. The average milk production of Garsi breed in different seasons was estimated and it was noticed that the highest average of 2460 ± 35 L milk production in spring season followed by 2434 ± 14 L in summer and lowest in winter, as 2413 ± 62 L respectively. The average milk production of CB Doragh breed in different seasons was estimated of 2540 ± 35 L milk production in spring season followed by 2457 ± 25 L in summer and lowest in winter, as 2432 ± 20 L respectively.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132101221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ligating Properties and Antimicrobial Studies of Metal (II) Complexes of Amoxicillin 阿莫西林金属(II)配合物的结扎性质及抗菌研究
Haya: The Saudi Journal of Life Sciences Pub Date : 2022-02-28 DOI: 10.36348/sjls.2022.v07i02.008
N. C, E. U, Nwafor I. A, N. E
{"title":"Ligating Properties and Antimicrobial Studies of Metal (II) Complexes of Amoxicillin","authors":"N. C, E. U, Nwafor I. A, N. E","doi":"10.36348/sjls.2022.v07i02.008","DOIUrl":"https://doi.org/10.36348/sjls.2022.v07i02.008","url":null,"abstract":"Researchers in recent years are working on different approaches to the problem of bacteria resistant to antibiotics through drug modification. The synthesis of metal drug complexes are becoming more popular than their parent drugs because they possess modified pharmacological, toxicological and physiochemical properties. In this study, amoxicillin complexes of copper and zinc (II) ions were synthesized using standard method. The complexes were characterized for aqueous solubility, UV-visible spectral, acid stability, and thermal stability and in-vitro antimicrobial activities. The results of the physiochemical properties showed evidence of complex formation between the metals and the ligand. The acid and thermal stability of amoxicillin complexes showed high acid and thermal stability than its parent form. In-vitro antimicrobial activity of amoxicillin and its complexes form were studied against Staphylococcus aureus and Pseudomonas aeruginosa. The results revealed that Amoxicillin complexes of copper (II) ions showed effective antibacterial effect on Staphylococcus aureus than its pure form while Amoxicillin Zn2+ showed lower antibacterial activity when compared to its parent drug. This study suggests that transition metal complexes of amoxicillin modify the properties of the parent drug.","PeriodicalId":219819,"journal":{"name":"Haya: The Saudi Journal of Life Sciences","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124200594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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