Sleep and Breathing最新文献

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The impact of OSA on benign prostatic hyperplasia and metabolic syndrome Nocturia: a central mechanism analysis. OSA 对良性前列腺增生和代谢综合征夜尿的影响:中心机制分析。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-26 DOI: 10.1007/s11325-024-03086-1
Tsai-Yu Wang, Chun-Te Wu, Yu-Hsiang Lin
{"title":"The impact of OSA on benign prostatic hyperplasia and metabolic syndrome Nocturia: a central mechanism analysis.","authors":"Tsai-Yu Wang, Chun-Te Wu, Yu-Hsiang Lin","doi":"10.1007/s11325-024-03086-1","DOIUrl":"https://doi.org/10.1007/s11325-024-03086-1","url":null,"abstract":"","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A genome-wide methylation analysis of Chinese Han patients with chronic insomnia disorder. 中国汉族慢性失眠症患者的全基因组甲基化分析。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-26 DOI: 10.1007/s11325-024-03145-7
Xiao Li, Xue Meng, Rong-Rong Zhao, Ya-Hui Xu
{"title":"A genome-wide methylation analysis of Chinese Han patients with chronic insomnia disorder.","authors":"Xiao Li, Xue Meng, Rong-Rong Zhao, Ya-Hui Xu","doi":"10.1007/s11325-024-03145-7","DOIUrl":"https://doi.org/10.1007/s11325-024-03145-7","url":null,"abstract":"<p><strong>Background: </strong>As the most common sleep disorder, chronic insomnia disorder (CID) has become a global health burden to the public. However, it remains unclear about the pathogenesis of this disease. Epigenetic changes may provide important insights into the gene-environment interaction in CID. Therefore, this study was conducted to investigate the DNA methylation pattern in CID and reveal the epigenetic mechanism of this disease.</p><p><strong>Methods: </strong>In this study, whole blood DNA was extracted from 8 CID patients (the CID group) and 8 healthy controls (the control group), respectively. Besides, genome-wide DNA methylation was detected by Illumina Human Methylation 850 K Beadchip. Moreover, the sleep quality and insomnia severity were evaluated by the Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI), respectively.</p><p><strong>Results: </strong>A total of 369 differentially methylated positions (DMPs) and 23 differentially methylated regions (DMRs) were identified between the CID and control groups. LHX6 was identified as the most important differentially methylated gene (DMG). The Gene Ontology (GO) analysis results corroborated that DMPs were significantly enriched in 105 GO terms, including cell signaling, homogenous cell adhesion of plasma membrane adhesion molecules, nervous system development, cell adhesion, and calcium ion binding. In addition, it was demonstrated that DMPs were significantly enriched in the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, including the hippo signaling pathway, Ras signaling pathway, and vitamin B6 metabolism. The DMR-related GO analysis results revealed the positive regulation of protein kinase activities.</p><p><strong>Conclusions: </strong>DNA methylation plays a critical role in the development of CID, and LHX6 is validated to be an important DMG.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical activity, body weight, and liver function as factors increasing Insomnia index among Korean adults: a cross-sectional analysis. 体育锻炼、体重和肝功能是增加韩国成年人失眠指数的因素:一项横断面分析。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-26 DOI: 10.1007/s11325-024-03094-1
Seung-Taek Lim, Eunjae Lee
{"title":"Physical activity, body weight, and liver function as factors increasing Insomnia index among Korean adults: a cross-sectional analysis.","authors":"Seung-Taek Lim, Eunjae Lee","doi":"10.1007/s11325-024-03094-1","DOIUrl":"https://doi.org/10.1007/s11325-024-03094-1","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to elucidate the relationship between physical activity, body weight, liver function, and insomnia in Korean adults, thereby providing a foundation for health promotion strategies.</p><p><strong>Methods: </strong>We recruited 11,645 adults (8,051 males and 3,594 females). Participants underwent assessments using the Korean version of the Insomnia Severity Index, measures of physical activity (PA), anthropometric data (body weight, height, body mass index [BMI], and waist circumference [WC]), and liver function (alanine aminotransferase, aspartate aminotransferase [AST], and gamma-glutamyl transferase).</p><p><strong>Results: </strong>One-way ANOVA revealed significant differences among male groups in height (p < .001), weight (p = .036), BMI (p = .002), diastolic blood pressure (p = .008), AST (p = .036), recreational PA (p = .026), moderate PA (p < .01), vigorous PA (p < .01), and moderate-to-vigorous PA (p < .001). Similarly, significant differences were found among female groups in height (p < .001), weight (p = .001), BMI (p = .006), WC (p = .013), moderate PA (p < .001), vigorous PA (p < .001), and moderate-to-vigorous PA (p < .001).</p><p><strong>Conclusion: </strong>To prevent insomnia, it is essential to enhance physical activity and manage factors related to body weight and liver function, such as BMI, WC, and AST. Increasing moderate-to-vigorous physical activity is particularly crucial, as it has a substantial positive impact on reducing body weight and improving liver function.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of hypoxia on interoception in patient with obstructive sleep apnea. 缺氧对阻塞性睡眠呼吸暂停患者内感知的影响
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-23 DOI: 10.1007/s11325-024-03143-9
Mahmut Bilal Çaman, Osman Saraydar, Serkan Aksu, Semai Bek, Gulnihal Kutlu
{"title":"The effect of hypoxia on interoception in patient with obstructive sleep apnea.","authors":"Mahmut Bilal Çaman, Osman Saraydar, Serkan Aksu, Semai Bek, Gulnihal Kutlu","doi":"10.1007/s11325-024-03143-9","DOIUrl":"https://doi.org/10.1007/s11325-024-03143-9","url":null,"abstract":"<p><strong>Purpose: </strong>Obstructive Sleep Apnea (OSA) is the most common sleep-related disorder. Interoception is the collection of sensory and cognitive processes that involve receiving and interpreting physiological signals from internal body structures and conveying the perception of inner sensations. In this study, it was hypothesized that the impairment in cognitive functions associated with chronic hypoxemia and the insular effects due to OSA would negatively affect interoceptive functions. The aim of this study was to evaluate whether interoception in OSA changes consistent with the hypothesis.</p><p><strong>Methods: </strong>A total of 102 patients diagnosed with OSA were included in this study. All participants were divided into groups based on their T90 values: desaturated OSA (T90 ≥ 20%) and non-desaturated OSA (T90 < 20%). The Heartbeat Counting Task was used to assess interoceptive accuracy, while the Interoceptive Sense Questionnaire (ISQ) was employed to identify subjective challenges in evaluating interoception.</p><p><strong>Results: </strong>Interoceptive accuracy was lower in the desaturated OSA group than in the non-desaturated OSA group (Z = -2.463; p = 0.014). Interoceptive accuracy was negatively correlated with the body mass index (r = -0.228; p = 0.021), T90 (r = -0.269; p = 0.006), and positively correlated with the average SaO2 (r = 0.377; p < 0.001) and SaO2 nadir (r = 0.243; p = 0.014).</p><p><strong>Conclusion: </strong>This study examined interoceptive functions in patients with OSA. It was concluded that interoceptive accuracy is affected by the severity of hypoxia as hypothesized.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The knowledge profile, attitudes, and perioperative management of Chinese anesthesiologists towards patients with obstructive sleep apnea: a cross-sectional survey. 中国麻醉医师对阻塞性睡眠呼吸暂停患者的知识概况、态度和围手术期管理:一项横断面调查。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-22 DOI: 10.1007/s11325-024-03119-9
Lingcan Tan, Zhongjing Pan, Qinghan Zeng, Yuanyuan Peng, Fengling Yang, Dan Lu
{"title":"The knowledge profile, attitudes, and perioperative management of Chinese anesthesiologists towards patients with obstructive sleep apnea: a cross-sectional survey.","authors":"Lingcan Tan, Zhongjing Pan, Qinghan Zeng, Yuanyuan Peng, Fengling Yang, Dan Lu","doi":"10.1007/s11325-024-03119-9","DOIUrl":"https://doi.org/10.1007/s11325-024-03119-9","url":null,"abstract":"<p><strong>Backgrounds: </strong>Obstructive sleep apnea syndrome (OSA) is increasingly encountered by anesthesiologists in clinical practice. However, research on managing these patients among anesthesiologists in China is scarce. This study aims to investigate the knowledge, attitudes, and perioperative management strategies for OSA patients among Chinese anesthesiologists.</p><p><strong>Methods: </strong>In this cross-sectional study, anesthesiologists from various hospitals across China were invited to complete a thirty-eight-item online questionnaire survey between October 1 and November 1, 2022. The Obstructive Sleep Apnea Knowledge and Attitude (OSAKA) scale was utilized to measure their knowledge and attitudes.</p><p><strong>Results: </strong>A total of 470 valid participants were recruited for this research, resulting in a valid response rate of 73.3%. (1) While the majority of participants acknowledged the importance of identifying OSA during perioperative management, only 58.3% felt confident in managing OSA patients; (2) Anesthesiologists with higher professional titles and longer work experience exhibited greater confidence in managing OSA patients; (3) Just under half of the participants were familiar with the STOP-Bang and Berlin questionnaires. Anesthesiologists with over 20 years of work experience were more likely to use the STOP-Bang and Berlin questionnaires compared to those with less than 10 years of work experience (OR = 3.166, P < 0.001); (4) 71.1% of participants expressed approval regarding the preparation of sugammadex for muscle relaxation reversal, while only 32.8% approved the safety of opioid use for postoperative analgesia in OSA patients.</p><p><strong>Conclusion: </strong>The study displayed that Chinese anesthesiologists have inadequate knowledge and perioperative management of OSA than expected. However, they have positive attitudes towards the assessment and management of OSA. The study highlights the need for high-quality training to identify and manage OSA among Chinese anesthesiologists.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient preference of level I, II and III sleep diagnostic tests to diagnose obstructive sleep apnoea among pregnant women in early to mid-gestation. 妊娠早中期孕妇对用于诊断阻塞性睡眠呼吸暂停的 I、II 和 III 级睡眠诊断测试的偏好。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-21 DOI: 10.1007/s11325-024-03114-0
Frances Clements, Hima Vedam, Yewon Chung, Nathaniel S Marshall, Kerri Melehan, Annemarie Hennessy, Angela Makris
{"title":"Patient preference of level I, II and III sleep diagnostic tests to diagnose obstructive sleep apnoea among pregnant women in early to mid-gestation.","authors":"Frances Clements, Hima Vedam, Yewon Chung, Nathaniel S Marshall, Kerri Melehan, Annemarie Hennessy, Angela Makris","doi":"10.1007/s11325-024-03114-0","DOIUrl":"https://doi.org/10.1007/s11325-024-03114-0","url":null,"abstract":"<p><strong>Purpose: </strong>There is a paucity of data on preferences for obstructive sleep apnoea (OSA) diagnostic tests during pregnancy. Simple test completion rates fail to capture patient preference or experience of completing sleep diagnostic tests. We assessed preference, ease of use, convenience, and the repeatability of level I, II and III sleep diagnostic tests, using questionnaires, in pregnant women in early to mid-gestation.</p><p><strong>Methods: </strong>Pregnant women with signs or symptoms of OSA, or at high risk of cardiometabolic disorders of pregnancy completed level I, II and III sleep studies by 24 weeks gestation. Participants then completed a questionnaire to rank test preference. Additional questionnaires assessed ease of use, convenience, and acceptability to repeat test, using 5-point Likert scale questions, yes/no response and optional linked text fields.</p><p><strong>Results: </strong>Of fifty-two consented participants, 43 completed any questionnaire (mean age 32.7 ± 5.4 years, BMI 32.7 ± 5.4, median gestation at Level I polysomnography (PSG) of 14.2 weeks (interquartile range (IQR) 13.5-17.6)). Of the 29 respondents who completed test ranking questionnaire, level III was the preferred test ((n = 21 / 29, 75%)), followed by level 1 (n = 6 / 29, 20.7%) and level II (n = 2 / 29, 7.1%) (p for diff < 0.001). Level III was reported the easiest test (very easy to complete) (n = 16, 51.6%), followed by level I(n = 10, 33.3%), and level II (n = 9, 9.1%) (p for diff < 0.001)). Level III was reported most convenient test (very convenient to complete) (n = 16, 51.6%), followed by level I (n = 4, 13.3%) and level II (n = 4, 13.3%) (p for diff < 0.001)). Level III was reported most acceptable to repeat (very acceptable to repeat) (n = 13, 41.9%), followed by level I (n = 3, 10.0%) and level II (n = 3, 10.0%) (p for diff < 0.001)).</p><p><strong>Conclusion: </strong>Pregnant women being assessed for OSA by 24 weeks gestation preferred to undertake level III sleep studies and found level III easier to use, more convenient and most acceptable to repeat than Level I and II studies. Given autonomy is an important principle, patient preference of sleep diagnostic tests should be taken into consideration in sleep clinical services and research involving pregnant women.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of physical activity and quality of life between obese individuals with obstructive sleep apnea syndrome and individuals with obesity hypoventilation syndrome. 患有阻塞性睡眠呼吸暂停综合征的肥胖者与患有肥胖低通气综合征的肥胖者在体育活动和生活质量方面的比较。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-20 DOI: 10.1007/s11325-024-03148-4
Aliki Karkala, Antonios Baxevanidis, Anastasia Chasiotou, Dimitra Siopi, Dimitra Mameletzi, Evangelia Kouidi, Diamantis Chloros, Georgia Pitsiou, Afroditi K Boutou
{"title":"Comparison of physical activity and quality of life between obese individuals with obstructive sleep apnea syndrome and individuals with obesity hypoventilation syndrome.","authors":"Aliki Karkala, Antonios Baxevanidis, Anastasia Chasiotou, Dimitra Siopi, Dimitra Mameletzi, Evangelia Kouidi, Diamantis Chloros, Georgia Pitsiou, Afroditi K Boutou","doi":"10.1007/s11325-024-03148-4","DOIUrl":"https://doi.org/10.1007/s11325-024-03148-4","url":null,"abstract":"<p><strong>Purpose: </strong>Obstructive Sleep Apnea Syndrome (OSAS) and Obesity Hypoventilation Syndrome (OHS) share common causal factors and comorbidities but may have a variable effect on physical activity and associated quality of life, due to differences in pathophysiology. The aim of this study was to compare the levels of physical activity, mental health and quality of life between matched obese patients with either OSAS or OHS, aiming to identify which of the two syndromes may impose the most severe impact on these variables, for the first time in literature.</p><p><strong>Methods: </strong>A total of 76 obese patients (OSAS: Ν1 = 48, OHS: N2 = 26) of similar age (58.2 ± 12.2 vs. 63.6 ± 9.8; p > 0.05), BMI (37.2 ± 6.2 vs. 40.3 ± 7.3; p > 0.05), and Apnea-Hypopnea Index (AHI) under non-invasive ventilation, completed International Physical Activity Questionnaire (IPAQ), Short-Form Health Questionnaire (SF-36), Personal Well-Being (PWB) Scale and Hospital Anxiety and Depression Scale (HADS-A and HADS-D), in this cross-sectional study.</p><p><strong>Results: </strong>Both groups had similar scores in SF-36, HADS-A and HADS-D, while prevalence of clinical cases of anxiety (HADS-A > 8) and depression (HADS-D > 8) were also similar. OSAS patients scored significantly higher in physical activity [absolute IPAQ values 1100.75(7753.5) for OSAS vs. 518(3806) for OHS; p = 0.029]. Group comparisons yielded significant differences in physical functioning (p < 0.05) and general health perceptions (p < 0.05), in favor of the OSAS group.</p><p><strong>Conclusion: </strong>Both syndromes significantly affect patients' quality of life and physical activity, with the burden being heavier for OHS patients. Daily physical activity seems to be more impaired among obese OHS patients perhaps due to daytime hypercapnia.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors predictive of extensive use of CPAP treatment in obstructive sleep apnoea. 阻塞性睡眠呼吸暂停患者广泛使用 CPAP 治疗的预测因素。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-20 DOI: 10.1007/s11325-024-03146-6
Fatma Doghman, Haitham Ballo, Ulla Anttalainen, Tarja Saaresranta
{"title":"Factors predictive of extensive use of CPAP treatment in obstructive sleep apnoea.","authors":"Fatma Doghman, Haitham Ballo, Ulla Anttalainen, Tarja Saaresranta","doi":"10.1007/s11325-024-03146-6","DOIUrl":"https://doi.org/10.1007/s11325-024-03146-6","url":null,"abstract":"<p><strong>Aim: </strong>In patients with obstructive sleep apnoea (OSA), the benefits of continuous positive airway pressure (CPAP) therapy are increased for every additional hour of daily CPAP usage. However, the data of predictors of extensive usage is scarce, if any. Therefore, we evaluated potential predictors affecting extensive treatment usage.</p><p><strong>Methods: </strong>In this retrospective study, we compiled an institutional cohort of consecutive patients diagnosed with who started CPAP therapy 1999-2022 and were included in a wireless telemonitoring system in May 2022 (N = 14,394). Patients using CPAP device ≥ 9 h/d were stratified into a younger (< 65 years; N = 124) and an older group (≥ 65 years; N = 131).</p><p><strong>Results: </strong>We found 255 patients (male 61%) eligible for our study, with a median age of 65 (interquartile range, IQR 55-73) years, and mean body mass index (BMI) of 36 ± 6.9 kg/m<sup>2</sup>. Median CPAP use was 10 h/d (IQR 10-11). BMI and depressive symptoms (DEPS) in the younger group were higher than in the older group (37.9 ± 7 vs. 34.6 ± 6.4 kg/m<sup>2</sup>, p < 0.001 and 11 (IQR 5-20) vs. 7 (IQR 5-14), p = 0.01, respectively). During follow-up, the BMI of the younger group increased (39.9 ± 12.5 kg/m<sup>2</sup> vs. 37.9 ± 7 kg/m<sup>2</sup>, p = 0.009). DEPS values decreased in the younger group and became comparable between the groups. In multivariate models, the baseline BMI independently predicted extensive CPAP use among the younger age group, and the mask leak among the older group.</p><p><strong>Conclusion: </strong>BMI at baseline in the younger and mask leak in the older group could be independent predictive factors for extensive use of CPAP.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of snoring on the risk of stroke in patients with diabetes mellitus. 打鼾对糖尿病患者中风风险的影响。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-16 DOI: 10.1007/s11325-024-03131-z
Eujene Jung, U Chul Ju, Hyun Ho Ryu, Hyun Lee Kim
{"title":"Impact of snoring on the risk of stroke in patients with diabetes mellitus.","authors":"Eujene Jung, U Chul Ju, Hyun Ho Ryu, Hyun Lee Kim","doi":"10.1007/s11325-024-03131-z","DOIUrl":"https://doi.org/10.1007/s11325-024-03131-z","url":null,"abstract":"<p><strong>Background: </strong>The impact of snoring and diabetes on stroke risk is unclear. This study examined the association between snoring and stroke risk and how it varies with diabetes mellitus (DM) status.</p><p><strong>Methods: </strong>This research was conducted as a prospective cohort study. A total of 4,352 subjects were included in the analysis, with a mean follow-up time of 13.7 years. The study used snoring history obtained through interviews as the primary exposure variable and DM as the secondary exposure variable. The main outcome measured was the occurrence of stroke. Cox regression analysis was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Additionally, a joint test was conducted to evaluate the combined effect of snoring and diabetes on the occurrence of stroke.</p><p><strong>Results: </strong>In our study of 4,352 subjects, 1,135 (26.1%) had a history of snoring, 233 (5.4%) had diabetes mellitus, and over the 18-year observation period, there were 168 cases of new-onset stroke. Snoring was not associated with an increased risk of stroke (HR: 0.95, 95% CI [0.68-1.33]), but DM significantly elevated the risk of stroke (3.02 [1.96-4.65]). In the interaction analysis of snoring and DM status on stroke risk, snoring was a significant risk factor for stroke only in the population with DM (2.89 [1.07-7.60]). Compared to non-snoring and non-DM, the multivariate HRs for stroke were 1.09 (0.76-1.57) for snoring and non-DM, 1.64 (0.83-2.82) for non-snoring and DM, and 2.95 (1.42-5.45) for snoring and DM.</p><p><strong>Conclusion: </strong>Diabetes mellitus was associated with an increased risk of stroke, while a history of snoring was not. In a sub analysis, snoring appeared to be associated with an increased risk of stroke among subjects with diabetes mellitus.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroticism affects nightmare distress through rumination. 神经质通过反刍影响噩梦痛苦。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2024-08-16 DOI: 10.1007/s11325-024-03135-9
Xiang Wang, Tamini Soondrum, Lisha Dai
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