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Long-term effects on blood pressure of soft tissue surgery for obstructive sleep apnea treatment in adults: a systematic review and meta-analysis.
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-04-05 DOI: 10.1007/s11325-025-03322-2
Sirisuit Ruengpolviwat, Prakobkiat Hirunwiwatkul, Natamon Charakorn
{"title":"Long-term effects on blood pressure of soft tissue surgery for obstructive sleep apnea treatment in adults: a systematic review and meta-analysis.","authors":"Sirisuit Ruengpolviwat, Prakobkiat Hirunwiwatkul, Natamon Charakorn","doi":"10.1007/s11325-025-03322-2","DOIUrl":"https://doi.org/10.1007/s11325-025-03322-2","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a systematic review and meta-analysis to evaluate long term effect of soft tissue surgery on blood pressure (BP) in adults with obstructive sleep apnea (OSA).</p><p><strong>Search methods: </strong>PubMed, Scopus, the Cochrane library, and Ovid Medline databases were searched through January 2024. Manual searches were also obtained. This review included studies assessing impact of soft tissue surgery for the treatment of OSA in adults on long-term BP.</p><p><strong>Result: </strong>A total of five studies (299 patients) met our inclusion criteria. Pooled random effects analysis demonstrated a statistically significant long-term postoperative reduction of BP, with average systolic BP reduction of 14.04 mmHg [95%CI (-21.97, -6.11); P = 0.0005]. Pooled random effects analysis of data from four studies (277 patients) also demonstrated statistically significant long-term postoperative reduction of diastolic BP by 6.88 mmHg compared with preoperative baseline [95%CI (-13.31, -0.45); P = 0.04].</p><p><strong>Conclusion: </strong>Soft tissue surgery for OSA treatment in adults significantly resulted in long-term blood pressure reduction.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"150"},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of physical activity in Obstructive Sleep Apnoea and their association with sleepiness.
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-04-04 DOI: 10.1007/s11325-025-03314-2
By Jack Callum, Yu Sun Bin, Kate Sutherland, Amanda Piper, Kristina Kairaitis, John Wheatley, Philip de Chazal, Brendon J Yee, Emmanuel Stamatakis, Peter A Cistulli
{"title":"Patterns of physical activity in Obstructive Sleep Apnoea and their association with sleepiness.","authors":"By Jack Callum, Yu Sun Bin, Kate Sutherland, Amanda Piper, Kristina Kairaitis, John Wheatley, Philip de Chazal, Brendon J Yee, Emmanuel Stamatakis, Peter A Cistulli","doi":"10.1007/s11325-025-03314-2","DOIUrl":"10.1007/s11325-025-03314-2","url":null,"abstract":"<p><strong>Objectives: </strong>Excessive daytime sleepiness (EDS) is a key symptom of Obstructive Sleep Apnoea (OSA). Both EDS and OSA affect, and are affected by, physical activity (PA). This study explores physical activity patterns in OSA patients and the association between activity and EDS.</p><p><strong>Methods: </strong>This is a retrospective analysis of cross-sectional data from the Sydney Sleep Biobank, which recruited sleep clinic patients between August 2018 and June 2022. Participants aged > 18 years with untreated OSA were included, while those with other sleep disorders or whose medication/work affected sleepiness were excluded. PA was assessed with the International Physical Activity Questionnaire (IPAQ), with intensity quantified by metabolic equivalent of task (MET). Subjective daytime sleepiness with quantified by the Epworth Sleepiness Scale (ESS).</p><p><strong>Results: </strong>Of 487 patients with OSA, 21% reported low (< 600 MET-min/week), 32% medium (600-2999 MET min/week), and 47% high PA ( > = 3000 MET-min/week). Participants with mild OSA were the most likely to be in the high PA group. ESS was not significantly associated with physical activity nor OSA severity, after adjustment for sex, age, body mass index, and sleep duration. Consideration of a potential interaction between physical activity and OSA severity did not change these results. However, in subgroup analysis of women only, severe OSA and medium and high levels of PA were linked to higher ESS scores.</p><p><strong>Conclusions: </strong>Greater physical activity was associated with higher daytime sleepiness in women, but not men. However, further research is needed to reproduce these findings using objective measures of physical activity and to examine if physical activity has direct benefits for daytime symptoms of OSA beyond sleepiness.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"147"},"PeriodicalIF":2.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of adherence to continuous positive airway pressure and mandibular advancement splints in pregnant individuals with sleep-disordered breathing.
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-04-04 DOI: 10.1007/s11325-025-03284-5
Joshua Smocot, Nelly Huynh, Pattaraporn Panyarath, R John Kimoff, Sara Meltzer, Léa Drouin-Gagné, Raphieal Newbold, Courtney Hebert, Andrea Benedetti, Jean-Patrick Arcache, Anne-Maude Morency, Natasha Garfield, Evelyne Rey, Sushmita Pamidi
{"title":"Patterns of adherence to continuous positive airway pressure and mandibular advancement splints in pregnant individuals with sleep-disordered breathing.","authors":"Joshua Smocot, Nelly Huynh, Pattaraporn Panyarath, R John Kimoff, Sara Meltzer, Léa Drouin-Gagné, Raphieal Newbold, Courtney Hebert, Andrea Benedetti, Jean-Patrick Arcache, Anne-Maude Morency, Natasha Garfield, Evelyne Rey, Sushmita Pamidi","doi":"10.1007/s11325-025-03284-5","DOIUrl":"https://doi.org/10.1007/s11325-025-03284-5","url":null,"abstract":"<p><strong>Purpose: </strong>Night-to-night adherence to sleep-disordered breathing (SDB) treatment with either continuous positive airway pressure (CPAP) or mandibular advancement splints (MAS) in pregnancy has not been well characterized. The objective of this study was to assess night-to-night adherence patterns from existing CPAP and MAS data in pregnancy.</p><p><strong>Methods: </strong>Three separate pregnancy cohorts evaluating treatment for SDB in the second and third trimester were used: 1) CPAP in gestational diabetes mellitus (GDM), 2) CPAP in hypertensive disorders of pregnancy (HDP), and 3) mandibular advancement splints (MAS). The first 30 days of objective adherence data obtained from CPAP and MAS devices were used in this descriptive analysis.</p><p><strong>Results: </strong>Data from 37 CPAP users and 15 MAS users was analyzed. For the GDM and HDP cohorts, three patterns of adherence were observed: 1) consistent CPAP users (38%), 2) improved CPAP usage after initial adaptation (16%), and 3) inconsistent CPAP users (46%). For the MAS cohort, the three observed patterns of adherence were: 1) consistent MAS users (47%), 2) initial usage with subsequent decrease in adherence (20%), and 3) inconsistent MAS users (33%). Participant characteristics (demographics, disease severity) were similar between adherence groups, with the exception of longer total sleep time in consistent CPAP users of the GDM cohort and greater gestational age in consistent CPAP users of the HDP cohort.</p><p><strong>Conclusion: </strong>Overall, objective night-to-night adherence patterns revealed that almost half of CPAP and MAS users had difficulty adapting to treatment in the first 30 days of treatment. Early usage patterns in pregnancy may provide insight into identifying patients who are at risk for poor adherence and for developing tailored and timely interventions to enhance adherence to therapy.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifiers: NCT02245659, NCT03309826, NCT03138291.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"148"},"PeriodicalIF":2.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of a multidisciplinary sleep apnea management group clinic on positive airway pressure adherence and patient-reported outcomes: a randomized controlled trial.
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-04-04 DOI: 10.1007/s11325-025-03319-x
Sepideh Khazaie, Reena Mehra, Raman Bhambra, Douglas E Moul, Nancy Foldvary-Schaefer, Robon Vanek, James Bena, Shannon Morrison, Harneet K Walia
{"title":"Impact of a multidisciplinary sleep apnea management group clinic on positive airway pressure adherence and patient-reported outcomes: a randomized controlled trial.","authors":"Sepideh Khazaie, Reena Mehra, Raman Bhambra, Douglas E Moul, Nancy Foldvary-Schaefer, Robon Vanek, James Bena, Shannon Morrison, Harneet K Walia","doi":"10.1007/s11325-025-03319-x","DOIUrl":"10.1007/s11325-025-03319-x","url":null,"abstract":"<p><strong>Introduction: </strong>Positive airway pressure (PAP) is the mainstay of treatment for obstructive sleep apnea (OSA). However, suboptimal adherence significantly limits its effectiveness. This study examined the impact of a Sleep Apnea Management (SAM) clinic-an innovative, interactive group intervention providing interpersonal support, education, and resources-on PAP adherence and patient-reported outcomes (PROs) compared to usual care.</p><p><strong>Methods: </strong>Participants with OSA who were newly prescribed PAP therapy and demonstrated suboptimal adherence (defined using CMS criteria during the first two weeks) were randomized to the SAM clinic (n = 26) or usual care (n = 30) from April 2019 to November 2022 (NCT-03835702). The primary outcome was the change in average daily PAP usage. Secondary outcomes included changes in the Epworth Sleepiness Scale (ESS), Patient Health Questionnaire-9 (PHQ-9), and PROMIS scales from baseline to 1 and 3 months. Baseline-adjusted mixed-effects linear and logistic models estimated differences between and within groups.</p><p><strong>Results: </strong>Fifty-six participants were enrolled with a mean age of 55 years, 57% female, 63% Caucasian, median AHI of 22.8 (IQR: 9.3,39.6), and median baseline PAP usage of 172 min. After 3 months, the mean (95% CI) SAM clinic daily PAP use was 193 (139, 247) minutes vs usual care at 148 (110, 185) minutes with a mean difference of 46(-8, 99) minutes per day (p = 0.093). Within each group, a mean daily difference of 11(-36,57) minutes (p = 0.65) in SAM clinic and -32(-75,12) (p = 0.15) in the usual care was observed. No significant differences were observed in PROs between SAM and usual care. Within each group, ESS change was -0.7(-2.5,1.2) (p = 0.48) in SAM clinic and -2.5(-4.2, -0.83) (p = .004) in usual care. Significant decrease was noted in PHQ-9 within both SAM clinic at-2.2(-3.9, -0.4) (p = 0.019) and in usual care at -2.3(-4.0, -0.7) (p = 0.006). Improvement in PROMIS sleep-related impairment was noted within both groups: SAM clinic at -3.0(-6.2,0.1) (p = 0.059) and usual care group at -3.5(-6.4, -0.60) (p = 0.019). Similar changes in PAP adherence and PROS were seen at the 1-month follow-up.</p><p><strong>Conclusion: </strong>The SAM clinic demonstrated trends toward improved PAP adherence and PROs compared to usual care, though differences were not statistically significant, likely reflecting the study's small sample size and other methodological constraints, larger, adequately powered studies are needed to confirm these findings and further explore the impact of SAM clinics on PAP adherence and patient outcomes.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"149"},"PeriodicalIF":2.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial.
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-04-01 DOI: 10.1007/s11325-025-03309-z
Siraj Omar Wali, Ghadah Batawi, Omar Kanbr, Nadeem Shafique Butt, Murad A Yasawy, Dalyah Alqaidi, Faris Alhejaili, Ranya Alshumrani, David Gozal
{"title":"Impact of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial.","authors":"Siraj Omar Wali, Ghadah Batawi, Omar Kanbr, Nadeem Shafique Butt, Murad A Yasawy, Dalyah Alqaidi, Faris Alhejaili, Ranya Alshumrani, David Gozal","doi":"10.1007/s11325-025-03309-z","DOIUrl":"https://doi.org/10.1007/s11325-025-03309-z","url":null,"abstract":"<p><strong>Purpose: </strong>Continuous positive airway pressure (CPAP) is the gold standard for managing moderate-to-severe obstructive sleep apnea (OSA). However, adherence to CPAP usage remains problematic with many patients either intermittently or permanently discontinuing CPAP use. However, the impact of CPAP therapy discontinuation remains unclear. This study aimed to evaluate the effects of complete and intermittent CPAP withdrawal on clinical and objective relapse of OSA.</p><p><strong>Patients and methods: </strong>This randomized study involved patients with moderate-to-severe OSA who were compliant with CPAP therapy. All subjects underwent a CPAP efficacy assessment (CPAP check), followed by 1 month of closely monitored CPAP usage. Subjects were then randomized into two groups: (1) complete CPAP withdrawal (NO-CPAP); (2) intermittent CPAP use (INT-CPAP) (using the device every other day). Clinical relapse was assessed daily and defined as reemergence of any of the OSA symptoms. Weekly home sleep testing was performed to assess OSA relapse objectively, defined as an apnea-hypopnea index (AHI) of > 5.</p><p><strong>Results: </strong>A total of 22 patients were included, with 12 subjects assigned to NO-CPAP group and 10 to the INT-CPAP group. Both groups exhibited a rapid recurrence of OSA within 1 week of CPAP discontinuation, with significant increases in AHI, oxygen desaturation index, and time spent with O<sub>2</sub> saturation < 90% compared to baseline CPAP-check parameters (p < 0.05). In addition, clinical relapse occurred earlier in ⁓70% of the INT-CPAP group (Median 2.9 days) and 33% in the NO-CPAP group (Median, 3.5 days) (p < 0.05). Age and neck circumference were identified as significant predictors of OSA relapse (p < 0.05).</p><p><strong>Conclusion: </strong>Discontinuation of CPAP therapy, whether completely or intermittently, leads to rapid OSA relapse, with age and neck circumference being key predictors of OSA relapse. These findings underscore the impact of CPAP withdrawal and the need for continuous CPAP adherence to effectively manage OSA.</p><p><strong>Clinical trial registration: </strong>A full trial protocol can be accessed through: https://clinicaltrials.gov/study/NCT05471765 .</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"146"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The yin and yang of sleep-wake regulation: gender gap in need for sleep persists across the human lifespan. 睡眠-觉醒调节的阴与阳:人类一生对睡眠需求的性别差异始终存在。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-03-30 DOI: 10.1007/s11325-025-03311-5
Arcady A Putilov, Evgeniy G Verevkin
{"title":"The yin and yang of sleep-wake regulation: gender gap in need for sleep persists across the human lifespan.","authors":"Arcady A Putilov, Evgeniy G Verevkin","doi":"10.1007/s11325-025-03311-5","DOIUrl":"https://doi.org/10.1007/s11325-025-03311-5","url":null,"abstract":"<p><strong>Purpose: </strong>Experiments on sleep regulation under the condition of self-selected light-dark and wake-sleep cycle revealed a larger sleep fraction in women than men. In questionnaire studies, women usually report a greater need for sleep than men. They also sleep more than men in overall and at most life course stages. However, much of the gap was explained by work/family responsibilities and gendered time tradeoffs. We tested whether females from childhood to late adulthood spend longer time in bed than males on weekends, and whether on weekdays, their time in bed fails to become longer due to the socially rather than biologically governed earlier weekday wake ups.</p><p><strong>Methods: </strong>A set of 340 paired subsamples of male and female sleep times was analyzed. The averaged sleep times were calculated and simulated.</p><p><strong>Results: </strong>Female-male difference in weekend time in bed attained the value of 0.26 h (the 0.16-h earlier bedtime was combined with the 0.10-h later risetime). The gender gap in weekday risetime was non-significant and the direction of gender difference in weekday time in bed was inconsistent across the lifespan. Model-based simulations provided support for the prediction that the male-female gap in sleep desire can reflect a higher level of sleep slow-wave activity (SWA) in females found in the vast majority of published studies.</p><p><strong>Conclusion: </strong>Since SWA is strongly indicative of age and age-associated change in neuronal networks, the persistency of female's greater desire for sleep can be explained by the underlying sex difference in age-associated structural changes in these networks.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"145"},"PeriodicalIF":2.1,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-time resistance training enhances sleep quality in obese and non-obese young women. 短时间阻力训练可提高肥胖和非肥胖年轻女性的睡眠质量。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-03-29 DOI: 10.1007/s11325-025-03310-6
Thaís Alves de Paiva Ferreira, Lucas Melo Neves, Alberto Jiménez-Maldonado, Larissa Kelly de Araújo Cardoso, Paulo Egdio Araújo Ferreira, Joniel Ronney Gomes da Silva, Clara Andressa de Araujo Barros, Nathanael Leal Santana, Ivoneide Maria Rodrigues de Araújo, Paula Alves Monteiro, Fabrício Eduardo Rossi
{"title":"Short-time resistance training enhances sleep quality in obese and non-obese young women.","authors":"Thaís Alves de Paiva Ferreira, Lucas Melo Neves, Alberto Jiménez-Maldonado, Larissa Kelly de Araújo Cardoso, Paulo Egdio Araújo Ferreira, Joniel Ronney Gomes da Silva, Clara Andressa de Araujo Barros, Nathanael Leal Santana, Ivoneide Maria Rodrigues de Araújo, Paula Alves Monteiro, Fabrício Eduardo Rossi","doi":"10.1007/s11325-025-03310-6","DOIUrl":"https://doi.org/10.1007/s11325-025-03310-6","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to examine the effects of short-term resistance training on sleep quantity and quality in young women, according to their body fat.</p><p><strong>Methods: </strong>Thirty-five young women were randomly assigned based on their body fat levels, using the 90th percentile of fat mass as a criterion, with a threshold set at ≥ 21 kg of fat mass for the obese group (n = 16) and < 21 kg of fat mass for the non-obese group (n = 19). Subjective sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI) at pre and post a progressive six-week full-body resistance training (RT).</p><p><strong>Results: </strong>Post-intervention analysis showed a reduction in the overall sleep score (p = 0.006, η2 = 0.21), improvement in subjective sleep quality (p < 0.001; η2 = 0.357) and a decrease in sleep disturbances (p = 0.034; η2 = 0.129). However, no interaction between group x training for sleep parameters and body composition was observed (p > 0.05). There were no significant correlations between sleep quality, fat mass and fat-free mass in both groups investigated (p > 0.05).</p><p><strong>Conclusion: </strong>Six-weeks of RT improved subjective sleep quality and reduced sleep disturbances in young women, regardless of the amount of fat mass. Sleep variables were not associated with changes in body composition.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"144"},"PeriodicalIF":2.1,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Richard Caton's "case of narcolepsy": obesity hypoventilation syndrome in the 1880s?
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-03-29 DOI: 10.1007/s11325-025-03299-y
Kariem Elhadd, Andrew J Larner
{"title":"Richard Caton's \"case of narcolepsy\": obesity hypoventilation syndrome in the 1880s?","authors":"Kariem Elhadd, Andrew J Larner","doi":"10.1007/s11325-025-03299-y","DOIUrl":"https://doi.org/10.1007/s11325-025-03299-y","url":null,"abstract":"<p><p>A literary account of an obese individual manifesting excessive daytime sleepiness, Joe the Fat Boy, appeared in Charles Dickens's work The Posthumous Papers of the Pickwick Club published in 1837. Adoption of the terms \"Pickwickian\" and \"Pickwickian syndrome\" in the medical literature did not occur until much later, for example by William Osler in 1918. We present a report published in 1889 by the English physician Richard Caton in which he described an obese patient with clinical evidence of excessive daytime sleepiness, nocturnal sleep apnoeas with persistent thoraco-abdominal movements, and cyanosis indicative of oxygen desaturation. Caton's carefully observed case adds to the history of obesity hypoventilation syndrome and obstructive sleep apnoea.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"143"},"PeriodicalIF":2.1,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Home sleep study nasal airflow patterns and epiglottic collapse during drug induced sleep endoscopy. 药物诱导睡眠内窥镜检查时的家庭睡眠研究鼻气流模式和会厌塌陷。
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-03-28 DOI: 10.1007/s11325-025-03305-3
Abhay Sharma, Jacob Noel, B Tucker Woodson
{"title":"Home sleep study nasal airflow patterns and epiglottic collapse during drug induced sleep endoscopy.","authors":"Abhay Sharma, Jacob Noel, B Tucker Woodson","doi":"10.1007/s11325-025-03305-3","DOIUrl":"https://doi.org/10.1007/s11325-025-03305-3","url":null,"abstract":"<p><strong>Purpose: </strong>Obstructive sleep apnea (OSA) is characterized by collapse of various portions of the pharynx. Epiglottic collapse is difficult to diagnose and may affect treatment tolerance. Previous research shows a distinct nasal airflow pattern during epiglottic obstruction characterized by signal discontinuities. It was hypothesized that primary epiglottic collapse characterized during drug-induced sleep endoscopy (DISE) correlates with nasal airflow discontinuity signals seen on home sleep studies.</p><p><strong>Methods: </strong>Patients with clinical records of undergoing both DISE and home portable sleep studies with raw data available from December 2016 to August 2021 were screened for epiglottic collapse or no epiglottic collapse using the VOTE scoring system. Any patient with tongue base collapse was excluded. Characterization of nasal airflow signals as discontinuities was based on previously published data. Acute flow discontinuities were scored by two blinded observers (AS, JN) from home cardiorespiratory studies using nasal pressure cannulas (Apnea Link Plus). Breath statistics (total number of breaths and flow limited breaths) for each patient were captured by the home cardiorespiratory device. DISE was performed under propofol anesthesia to a Ramsay level 5. Epiglottic collapse was described by shape, direction (AP or lateral), and timing (prolonged or intermittent).</p><p><strong>Results: </strong>The home sleep studies and DISE of 18 patients being considered for surgical therapies were retrospectively analyzed. Patients included had either complete (n=11) or no epiglottic collapse (n=7). The mean AHI was 21.3 and 19.7, respectively. There was a significant difference between nonepiglottic and epiglottic collapse groups in the total discontinuity breaths (median 7 vs 29, p=0.002), discontinuity breaths/hour (median 0.91 vs 5.3, p=0.001), and fraction of discontinuity breaths over total flow limited breaths (0.5% vs 1.9%, p=0.001). Morphological changes in epiglottic collapse did not affect discontinuities.</p><p><strong>Conclusion: </strong>The data from this study demonstrates nasal airflow signals from home sleep studies correlate with DISE epiglottic collapse.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"142"},"PeriodicalIF":2.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between dysfunctional beliefs and attitudes about sleep and mental health in medical staff: the mediating role of sleep quality.
IF 2.1 4区 医学
Sleep and Breathing Pub Date : 2025-03-27 DOI: 10.1007/s11325-025-03283-6
Benhong Wang, Zhong Wang, Xiaomei Zhang, Yanbin Ji, Yibin Shuai, Yinping Shen, Zhongxia Shen, Wenhao Chen
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