Sleep and Breathing最新文献

{"title":"Effect of obstructive sleep apnea risk on sialorrhea in patients with Parkinson's disease.","authors":"Özge Özkutlu, Esma Demir, Nezehat Özgül Ünlüer, Rıza Sonkaya","doi":"10.1007/s11325-024-03234-7","DOIUrl":"https://doi.org/10.1007/s11325-024-03234-7","url":null,"abstract":"<p><strong>Background: </strong>Our aim was to determine the effect of obstructive sleep apnea syndrome (OSAS) risk on sialorrhea in patients with Parkinson's disease (PD).</p><p><strong>Methods: </strong>A total of 75 patients with PD (mean age 66.36 ± 8.07) were included. Sialorrhoea was evaluated using the \"Sialorrhoea Clinical Scale for Parkinson's Disease\" and OSAS risk was determined using the STOP-Bang questionnaire. Diurnal and nocturnal sialorrhoea, drooling severity, speech impairment, eating impairment frequency of drooling, and social discomfort were evaluated. Patients were classified as having low, moderate, or high risk of OSAS. One-way analysis of variance, Tukey's multiple comparison test, Kruskal-Wallis test, Bonferroni-Dunn tests, and Fischer's exact test were used to compare groups according to the normality of the data.</p><p><strong>Results: </strong>Patients were classified as low risk (n = 10), intermediate risk (n = 29) and high risk (n = 36). The clinical characteristics were similar in all risk groups. The highest rate of nocturnal sialorrhea was observed in all risk groups. The lowest-risk group scored 4.30 ± 3.09, whereas the intermediate- and high-risk groups scored 4.21 ± 4.46, 6.94 ± 4.81 respectively for sialorrhea (p = 0.034). A significant difference in sialorrhea between the groups was found in the intermediate and high-risk groups (p = 0.034).</p><p><strong>Conclusion: </strong>This study showed that sialorrhea changes were significant in patients with PD in the intermediate-and high-risk OSAS groups. It may be suggested that sialorrhoea be assessed and included in the treatment program in patients at high risk of OSAS or that PD patients with high levels of sialorrhoea should be tested for OSAS. Patients may benefit from treatment methods that address both conditions.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"70"},"PeriodicalIF":2.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of continuous positive airway pressure therapy on early atherosclerosis in patients with severe obstructive sleep apnea-hypopnea syndrome.","authors":"Dóra Sulina, Szilvia Puskás, Mária Tünde Magyar, László Oláh, Norbert Kozák","doi":"10.1007/s11325-024-03189-9","DOIUrl":"10.1007/s11325-024-03189-9","url":null,"abstract":"<p><strong>Purpose: </strong>Obstructive sleep apnea-hypopnea syndrome (OSAHS) is the most common sleep-related breathing disorder. Longer term, repeated episodes of hypercapnia and hypoxemia during sleep are associated with inflammatory and atherosclerosis-related factors. The aim of this study was to explore the effect of continuous positive airway pressure (CPAP) therapy on cerebral vasoreactivity and early atherosclerosis in patients with severe OSAHS.</p><p><strong>Methods: </strong>Forty-one patients with severe OSAHS were enrolled. The mean follow-up time was 39.8 ± 9.1 months. Cardiovascular risk factors were assessed, and laboratory tests, carotid artery intima-media thickness (CIMT) measurement and cerebrovascular reserve capacity (CRC) measurement were performed. After the baseline examination, 28 patients received CPAP therapy (treated group), which was not available for 13 patients (untreated group). Parameters were compared before and after treatment, between treated and untreated patients.</p><p><strong>Results: </strong>Cardiovascular risk factors, baseline polysomnographic parameters, laboratory values, CIMT and CRC of the two groups were similar at baseline. At the follow-up, CRC did not differ between the two groups, but CIMT was significantly lower in the treated group than in the untreated group (0.73 ± 0.11 mm vs. 0.84 ± 0.21 mm, p = 0.027). The CIMT of both groups increased significantly during the follow-up period (from 0.65 ± 0.11 mm to 0.73 ± 0.11 mm in the treated group, and from 0.69 ± 0.11 mm to 0.84 ± 0.21 mm in the untreated group), but the increase in the treated group was smaller than in the untreated group (0.09 ± 0.09 mm vs. 0.15 ± 0.15 mm).</p><p><strong>Conclusion: </strong>In patients with severe OSAHS, CPAP treatment significantly reduced the progression of CIMT.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"71"},"PeriodicalIF":2.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with lower forced vital capacity in children and adults with Duchenne muscular dystrophy using non-invasive ventilation: a multicenter analysis.","authors":"Kanokkarn Sunkonkit, Manju Hurvitz, Andrew Defante, Jeremy Orr, Abhishek Chakraborty, Reshma Amin, Rakesh Bhattacharjee","doi":"10.1007/s11325-024-03183-1","DOIUrl":"10.1007/s11325-024-03183-1","url":null,"abstract":"<p><strong>Background: </strong>Reduced forced vital capacity (FVC) is associated with morbidity and mortality in individuals with Duchenne muscular dystrophy (DMD). Non-invasive ventilation (NIV) is often prescribed for the treatment of sleep-disordered breathing (SDB), and chronic respiratory insufficiency. Despite the common practice of initiating NIV later in the progression of DMD, the factors influencing FVC subsequent to the commencement of NIV remain unclear.</p><p><strong>Objective: </strong>To evaluate the demographic, clinical and socioeconomic determinants of FVC% predicted across several cohorts of DMD children and adults prescribed NIV.</p><p><strong>Methods: </strong>A multicenter retrospective review of individuals with DMD prescribed NIV was performed between February 2016 to October 2020. Patients were identified from three sites: The Hospital for Sick Children, Canada; Rady Children's Hospital San Diego, USA; and University of California San Diego Health, USA. Multivariate regression analysis was performed to determine factors that influence FVC.</p><p><strong>Results: </strong>Fifty-nine male patients with DMD prescribed NIV (mean ± SD for age and BMI was 20.1 ± 6.7 years and 23.8 ± 8.8 kg/m²) were included. Following multivariate analysis, a lower FVC% predicted was associated with older age (β = -1.44, p = 0.001), presence of scoliosis (β = -16.94, p = 0.002), absent deflazacort prescription (β = 14.43, p = 0.009), and use of in-ex sufflator (β = -39.73, p < 0.001), respectively.</p><p><strong>Conclusion: </strong>In our study, several factors were associated with reduced FVC% predicted in a DMD population using NIV. Future, prospective, longitudinal studies are imperative to comprehend the trajectory of FVC% predicted over time in individuals with DMD using NIV.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"68"},"PeriodicalIF":2.1,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergic rhinitis may attenuate the sympathovagal imbalances in patients with severe obstructive sleep apnea: pilot study using a heart rate variability analysis.","authors":"Tae Su Kim, Jun Yeon Won, Eui-Cheol Nam, Yoon-Jong Ryu, Young Ju Jin, Woo Hyun Nam, Ji-Su Jang, Jeong-Whun Kim, Woo Hyun Lee","doi":"10.1007/s11325-024-03203-0","DOIUrl":"https://doi.org/10.1007/s11325-024-03203-0","url":null,"abstract":"<p><strong>Purpose: </strong>The effect of allergic rhinitis (AR) on autonomic nervous system in patients with obstructive sleep apnea (OSA) remains unclear. We utilized heart rate variability (HRV) analysis to assess cardiac autonomic activity in patients with OSA, comparing those with and without allergic rhinitis (AR).</p><p><strong>Methods: </strong>We enrolled 182 patients who visited our sleep clinic complaining of habitual snoring or apnea during sleep. All patients underwent full-night polysomnography (PSG) and multiple allergen simultaneous tests. We calculated the HRV extracted from the electrocardiography of the PSG. Participants were divided into a normal group and an AR group, and HRV indices were compared according to OSA severity in each group.</p><p><strong>Results: </strong>The low-frequency (LF) to high-frequency (HF) ratio (LF/HF; r = 0.336, p < 0.001), LF normalised unit (LFnu; r = 0.345, p < 0.001), and HFnu (r = -0.345, p < 0.001) were significantly correlated with the apnea-hypopnea index. The HRV index comparison between non-severe and severe OSA in the normal group showed significant differences in LFnu (64.7 ± 12.5 in non-severe and 72.4 ± 11.7 in severe, p < 0.001), LF/HF (2.3 ± 1.6 in non-severe and 3.3 ± 2.0 in severe, p = 0.002), and HFnu (35.3 ± 12.5 in non-severe and 27.6 ± 11.7 in severe, p < 0.001). However, in the AR group, LFnu (p = 0.648), LF/HF (p = 0.441), and HFnu (p = 0.648) were comparable between non-severe and severe OSA.</p><p><strong>Conclusion: </strong>Considering that LFnu, HFnu, and LF/HF represent sympathetic activity, parasympathetic activity, and sympathovagal balance, respectively, AR may attenuate the sympathetic predominance and sympathovagal imbalance associated with cardiovascular morbidity in severe OSA.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"69"},"PeriodicalIF":2.1,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between REI and PSA in patients with obstructive sleep apnea: a prospective case-control study.","authors":"Lijuan Yang, Ying Feng, Jianhua Xue, Jianguang Tian, Yunle Wang","doi":"10.1007/s11325-024-03182-2","DOIUrl":"10.1007/s11325-024-03182-2","url":null,"abstract":"<p><strong>Background: </strong>Obstructive sleep apnea has been associated with various urinary system diseases, including prostatic hyperplasia and nocturia. Recently, it has been linked to prostate cancer. This study investigated the relationship between the apnea hypopnea index, prostate-specific antigen (PSA) levels, and changes in PSA.</p><p><strong>Methods: </strong>A total of 673 male patients who received portable sleep monitoring were assessed. All participants underwent thorough health assessments, including PSA testing. Individuals in Study 1 were divided into OSA and control groups based on an REI (Respiratory event index) ≥ 15 events/h. In Study 2, 176participants from the initial study were retested for PSA after three years.</p><p><strong>Results: </strong>In Study 1, patients with OSA had significantly higher ln-transformed PSA levels than controls (P < 0.05). Ln-transformed PSA levels showed a positive correlation with the REI (r = 0.184, p = 0.015). In Study 2, after three years, the ln-transformed PSA level increased by 0.13 ng/ml in the OSA group, while it decreased by -0.05 ng/ml in the control group. The change in ln-transformed PSA was significantly higher in patients with OSA (p = 0.014). Even after adjusting for age, body mass index (BMI), smoking, hypertension, and diabetes, REI remained a significant predictor of PSA level changes (β = 0.226, 95% CI = 0.001-0.009; p = 0.008).</p><p><strong>Conclusions: </strong>This study highlights the close relationship between REI and PSA levels in individuals with obstructive sleep apnea, indicating that REI is an independent risk factor for PSA levels. Obstructive sleep apnea may be associated with the incidence of prostate cancer.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"67"},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of light therapy on insomnia: A systematic review and meta-analysis.","authors":"Yi Wang, Xianchao Zhao, Jiafeng Ren, Shengwen Xue, Yuhang Liu, Liping Zhang, Mengmeng Fan, Changjun Su, Jin-Xiang Cheng","doi":"10.1007/s11325-024-03204-z","DOIUrl":"https://doi.org/10.1007/s11325-024-03204-z","url":null,"abstract":"<p><strong>Purpose: </strong>Light is a crucial factor influencing sleep arousal patterns. This meta-analysis investigates the efficacy of light therapy (LT) for insomnia treatment.</p><p><strong>Methods: </strong>Five electronic databases were independently searched by two reviewers until August 2024. The literature screening focused specifically on populations with insomnia complaints treated by LT. Weighted Mean Difference (WMD) and 95% Confidence Interval (CI) were used as statistical tools, while the Cochrane Risk of Bias tool version 2 (RoB 2) was employed to assess the quality of evidence. A total of 10 randomized controlled trials (RCTs) were analyzed.</p><p><strong>Results: </strong>The results demonstrated that LT showed statistically significant improvements in subjective sleep quality, as evidenced by a reduction in Pittsburgh sleep quality scale (PSQI) scores by -2.89 (95% CI = -4.80 to -0.97) and Insomnia severity index (ISI) scores by -2.16 (95% CI = -4.23 to -0.08) post-intervention. Additionally, actigraphy revealed a statistically significant increase in total sleep time (TST) by 16.78 min (95% CI = 0.67 to 32.89) and a decrease in wake after sleep onset (WASO) by -12.91 min (95% CI = -25.62 to -0.20) by LT.</p><p><strong>Conclusion: </strong>The preliminary results of the study suggest that LT has some efficacy in improving sleep quality in insomnia. However, it needs to be validated in future clinical trials with larger samples.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"66"},"PeriodicalIF":2.1,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive symptoms after surgical and medical management of OSA: a systematic review and meta-analysis.","authors":"Alejandro R Marrero-Gonzalez, Craig D Salvador, Shaun A Nguyen, Ted A Meyer, Dee W Ford, Andrea M Rinn, Chitra Lal, Melissa Swanson, Mohamed Abdelwahab","doi":"10.1007/s11325-024-03235-6","DOIUrl":"10.1007/s11325-024-03235-6","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of CPAP and surgical alternatives for OSA on depression and compare the results of surgery to CPAP. ​METHODS: COCHRANE Library, CINAHL, PubMed, and Scopus databases were searched for English-language articles. Meta-analysis of continuous measures (mean), proportions (%), and mean difference (Δ) with 95% confidence interval was conducted for objective and subjective outcomes before and after treatment with CPAP or surgical interventions.</p><p><strong>Results: </strong>We identified 2018 abstracts, 14 studies (N = 3,488) were included in the meta-analysis. Both treatments witnessed significant improvement in Apnea-hypopnea Index (AHI), with similar improvement with CPAP (Δ-48.8 [-51.2, -46.4]) and surgical interventions (Δ -20.22 [-31.3, -9.17]). An improvement in Epworth Sleepiness Scale (ESS) was noted between groups with (Δ -3.9 [-6.2, -1.6]) for the CPAP group and (Δ -4.3 [-6.0, -2.5]) for surgical interventions. The improvement of BDI II depression scores pre- and post-treatment was comparable between treatments with (Δ -4.1 [-5.8, -2.4]) for the CPAP group and (Δ- 5.6 [-9.2, -2.0]) for surgical interventions.</p><p><strong>Conclusion: </strong>Our findings suggest a reduction in AHI is seen in both CPAP and surgical interventions for OSA, with no difference in AHI reduction between groups. Both treatments also lead to a similar improvement in depression scores providing strong evidence regards impact of surgery on OSA-associated mood disorders. While percent reduction in depression is higher in the surgical group, the difference did not reach statistical significance when compared to CPAP. When stratified by surgical intervention, most interventions suggest an improvement in depression scores.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"64"},"PeriodicalIF":2.1,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of sleep deprivation on the balance system: following normal sleep, 24 h of sleep deprivation, and rest under eyes-open and eyes-closed conditions.","authors":"Menekşe Karahan, Enis Uluçam, Metehan Pehlivan, Didem Dönmez Aydın, Eren Ogut","doi":"10.1007/s11325-024-03217-8","DOIUrl":"https://doi.org/10.1007/s11325-024-03217-8","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the effects of sleep deprivation (SD) on balance after normal sleep, 24 h of SD, and subsequent rest under eyes-open (EO) and eyes-closed (EC) conditions. Our aim was to ascertain whether the reduced efficiency of balance control following SD is generalized or selective.</p><p><strong>Method: </strong>Nineteen participants (12 females, 7 males) completed the Pittsburgh Sleep Quality Index (PSQI). The mean ages for male participants were 24.14 ± 0.37 years, their height was 180.71 ± 5.46 cm, and weight of male participants were 81.71 ± 13.42 kg. For female participants, the mean ages were 24.41 ± 4.01 years, their height was 163.66 ± 2.64 cm, and their weight was 59.54 ± 9.18 kg. Stance analyses were conducted after normal sleep, 24 h of SD, and subsequent rest of both the EO and EC. Participants performed a normal balance test, a second test while holding cubes and counting backwards from 200 by sevens, and a third test after rest under EO and EC.</p><p><strong>Results: </strong>Independent samples t-tests showed significant height and weight differences between sexes (p < 0.05), with females generally smaller. No significant differences were found in age, daytime sleep duration, or PSQI score (p > 0.05). Significant differences in parameters such as length of the minor axis (lomna), angle, and area were observed in EO and EC across the three days, revealing the interplay between visual stimuli, cognitive tasks, and parameter stability.</p><p><strong>Conclusion: </strong>SD has multifaceted impacts on motor and cognitive performance, even when attentional and sensory resources are not strained. Our findings elucidate the nuanced impact of SD on cognitive performance, and suggest the efficacy of external factors in mitigating its effects on postural control.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"65"},"PeriodicalIF":2.1,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are noradrenergics combined with antimuscarinics the future pharmacologic treatment for obstructive sleep apnea? A systematic review and meta-analysis of randomized controlled trials.","authors":"Zeyad Bady, Hazem E Mohammed, Heba Aboeldahab, Mahmoud Samir, Mohamed Smail Aissani, Aliaë A R Mohamed-Hussein","doi":"10.1007/s11325-024-03227-6","DOIUrl":"10.1007/s11325-024-03227-6","url":null,"abstract":"<p><strong>Purpose: </strong>Noradrenergics and antimuscarinics have been proposed as future pharmacotherapy for obstructive sleep apnea (OSA). However, the available randomized controlled trials (RCTs) showed heterogeneous results regarding the safety and efficacy of the combined regimen in OSA. Therefore, we performed this meta-analysis from the published RCTs to clarify this conflicting evidence.</p><p><strong>Methods: </strong>A systematic search of four electronic databases was done till December 2023.</p><p><strong>Results: </strong>Thirteen RCTs (n = 345) were systematically reviewed and meta-analyzed. The combined regimen significantly reduced apnea-hypopnea index (AHI): AHI 3% [events/h; Mean difference (MD): - 6.30; 95% Confidence interval (CI) (- 9.74, - 2.87); P = 0.0003], AHI 4% [events/h; MD: - 6.50; 95% CI (- 8.74, - 4.26 events/h); P < 0.00001]. All gasometric measures significantly improved in the combined regimen group except mean SpO2. No difference was found in total sleep time between the treatment and placebo. However, compared to placebo, the combined regimen altered sleep architecture and decreased sleep efficiency. Regarding OSA endotypes, the combined regimen significantly improved loop gain, pharyngeal muscle compensation, pharyngeal muscle recruitment, and respiratory arousal threshold.</p><p><strong>Conclusion: </strong>The combined regimen effectively reduces AHI and OSA severity with improvement in almost all OSA endotypes. However, this regimen decreased sleep efficiency and altered sleep architecture. Short-term side effects can be confined to increased heart rate, dry mouth and urinary hesitancy. Therefore, noradrenergics and anti-muscarinics is a promising regimen for treating OSA, yet this optimism must be titrated by the lack of long-term effects of the regimen. Future RCTs with focus on the long-term efficacy of the regimen and cardiovascular outcomes is recommended.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"63"},"PeriodicalIF":2.1,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The deficiencies of epworth sleepiness scale in the evaluation of excessive daytime sleepiness in obstructive sleep apnea and related factors.","authors":"Canan Gunduz Gurkan, Sema Sarac, Ezgi Yukcu Memis, Fatma Ozbaki","doi":"10.1007/s11325-024-03233-8","DOIUrl":"https://doi.org/10.1007/s11325-024-03233-8","url":null,"abstract":"<p><strong>Background: </strong>Epworth Sleepiness Scale(ESS) is widely used in the assessment of excessive daytime sleepiness (EDS) despite certain deficiencies. It was aimed to evaluate the factors associated with low ESS scores in subjects investigated for OSA.</p><p><strong>Methods: </strong>In this cross sectional study, we recorded the ESS and Pittsburg sleep quality index (PSQI) scores of patients undergoing polysomnography in our sleep center between November 2022-January 2023. Additional questions regarding literacy, vehicle use, driver licence and travelling habits were asked. Sleep indices of patients with AHI ≥ 5 were recorded following PSG.</p><p><strong>Results: </strong>96 patients with mean age 51 ± 12, 68% male, median AHI 34.6 (7-105), ESS 7 (0-22), PSQI 9 (2-15) were included. Among moderate-severe OSA patients without EDS; 10% were illiterate, 67% performed reading only from cellular phone, 88% did not attend the social settings, 53% did not travel frequently and 40% did not use any vehicle. The listed factors were also associated with low ESS (p < 0.001). The sleep indices and PSQI scores of patient groups with and without EDS were similar. There was a correlation between ESS and total PSQI score (β = 0.31, p = 0.002) and subjective sleep quality (β = 0.21, p = 0.04), sleep disturbances (β = 0.29, p = 0.004) and daytime dysfunction (β = 0.49, p < 0.001) domains.</p><p><strong>Conclusion: </strong>ESS may be inadequate in the assessment of the demographical features and daily habits of patients from different sociocultural settings. Clinicians should be aware that the patients may have severe OSA and poor sleep quality despite low ESS scores and should evaluate each patient individually.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 1","pages":"62"},"PeriodicalIF":2.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}