SLEEP Advances最新文献

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“What if that’s your last sleep?”: A qualitative exploration of the trauma of incarceration and sleep "如果这是你最后一觉怎么办?对监禁创伤和睡眠的定性探索
SLEEP Advances Pub Date : 2023-12-27 DOI: 10.1093/sleepadvances/zpad055
Johanna E. Elumn, Patrick Li, Malcolm S Lytell, Marisol Garcia, Emily A. Wang, H. Yaggi
{"title":"“What if that’s your last sleep?”: A qualitative exploration of the trauma of incarceration and sleep","authors":"Johanna E. Elumn, Patrick Li, Malcolm S Lytell, Marisol Garcia, Emily A. Wang, H. Yaggi","doi":"10.1093/sleepadvances/zpad055","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad055","url":null,"abstract":"Sleep is an underexplored factor in the health of people involved in the criminal legal system. This study addresses the paucity of research on how individual, social, and physical environmental factors impact sleep health during and after incarceration by highlighting the voices of people involved in the criminal legal system through a community-engaged qualitative research approach. We conducted 20 semi-structured interviews with men recently released from prison for a study on trauma and healthcare during incarceration and after release. Interviews were coded and analyzed using reflexive thematic analysis and a critical realist framework. Our research team included people with a history of incarceration who performed central roles in the research process. Three themes emerged from participants’ descriptions of sleep during and after incarceration: (1) concerns about health contributing to sleep problems, (2) lack of access to treatment for sleep disorders leading to ongoing sleep problems, and (3) issues of safety contributing to sleep problems during incarceration and after release. This study identifies factors and domains influencing sleep during and after incarceration. By identifying which interpersonal, environmental, and structural factors impact sleep quality, medical and carceral staff are better equipped to ameliorate sleep health disparities within populations with a history of incarceration and those actively bound by the criminal legal system. Future research should examine other factors impacting sleep in incarcerated and recently released populations and develop multi-level interventions to improve sleep health.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"48 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index 与呼吸暂停-低通气指数相比,呼吸事件指数低估了睡眠呼吸暂停的严重程度
SLEEP Advances Pub Date : 2023-12-22 DOI: 10.1093/sleepadvances/zpad054
M. Pitkänen, R. K. Nath, H. Korkalainen, Sami Nikkonen, Alaa Mahamid, A. Oksenberg, B. Duce, Juha Töyräs, S. Kainulainen, T. Leppänen
{"title":"Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index","authors":"M. Pitkänen, R. K. Nath, H. Korkalainen, Sami Nikkonen, Alaa Mahamid, A. Oksenberg, B. Duce, Juha Töyräs, S. Kainulainen, T. Leppänen","doi":"10.1093/sleepadvances/zpad054","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad054","url":null,"abstract":"Polygraphy (PG) is often used to diagnose obstructive sleep apnea (OSA). However, it does not use electroencephalography (EEG), and therefore cannot estimate sleep time or score arousals and related hypopneas. Consequently, the PG-derived respiratory event index (REI) differs from the polysomnography (PSG) derived apnea-hypopnea index (AHI). In this study, we comprehensively analyzed the differences between AHI and REI. Conventional AHI and REI were calculated based on total sleep time (TST) and total analyzed time (TAT), respectively, from two different PSG datasets (N=1561). Moreover, TAT-based AHI (AHITAT) and TST-based REI (REITST) were calculated. These indices were compared keeping AHI as the gold standard. The REI, AHITAT, and REITST were significantly lower than AHI (p<0.0001, p≤0.002, p≤0.01, respectively). The total classification accuracy of OSA severity based on REI was 42.1% and 72.8% for two datasets. Based on AHITAT the accuracies were 68.4% and 85.9%, and based on REITST they were 65.9% and 88.5% compared to AHI. AHI was most correlated with REITST (r=0.98 and r=0.99 for the datasets) and least with REI (r=0.92 and r=0.97). Compared to AHI, REI had the largest mean absolute error (13.9 and 6.7) and REITST the lowest (5.9 and 1.9). REI had the lowest sensitivity (42.1% and 72.8%) and specificity (80.7% and 90.9%) in both datasets. Based on these present results, REI underestimates AHI. Furthermore, these results indicate that arousal-related hypopneas are an important measure for accurately classifying OSA.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"42 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139164431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fear of sleep in first responders: Associations with trauma types, psychopathology, and sleep disturbances 急救人员的睡眠恐惧:与创伤类型、精神病理学和睡眠障碍的关系
SLEEP Advances Pub Date : 2023-12-01 DOI: 10.1093/sleepadvances/zpad053
A. Reffi, D. Kalmbach, Philip Cheng, Peter C Tappenden, Jennifer Valentine, Christopher L. Drake, W. Pigeon, Scott M. Pickett, Michelle M Lilly
{"title":"Fear of sleep in first responders: Associations with trauma types, psychopathology, and sleep disturbances","authors":"A. Reffi, D. Kalmbach, Philip Cheng, Peter C Tappenden, Jennifer Valentine, Christopher L. Drake, W. Pigeon, Scott M. Pickett, Michelle M Lilly","doi":"10.1093/sleepadvances/zpad053","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad053","url":null,"abstract":"\u0000 \u0000 \u0000 Fear of sleep contributes to insomnia in some individuals with posttraumatic stress disorder (PTSD) but remains uncharacterized in first responders, a population with high rates of insomnia and PTSD. We evaluated the clinical relevance of fear of sleep in first responders by (1) examining its relationship with trauma types and clinical symptoms and (2) assessing differences in fear of sleep severity between those reporting provisional PTSD, insomnia, or both.\u0000 \u0000 \u0000 \u0000 A cross-sectional study of 242 first responders across the US (59.2% male, 86.4% White, 56.2% law enforcement officers, 98.7% active duty, Myears of service = 17). Participants completed the Fear of Sleep Inventory – Short Form and measures of trauma history, psychopathology (e.g., PTSD), and sleep disturbances (insomnia and trauma-related nightmares).\u0000 \u0000 \u0000 \u0000 Fear of sleep was associated with trauma types characterized by interpersonal violence and victimization, as well as symptoms of PTSD, depression, anxiety, stress, alcohol use problems, insomnia, and trauma-related nightmares. Fear of sleep was most pronounced among first responders reporting provisional PTSD comorbid with insomnia compared to those with PTSD or insomnia only. Post hoc analyses revealed PTSD hyperarousal symptoms and trauma-related nightmares were independently associated with fear of sleep, even after adjusting for the remaining PTSD clusters, insomnia, sex, and years of service.\u0000 \u0000 \u0000 \u0000 Fear of sleep is a clinically relevant construct in first responders that is associated with a broad range of psychopathology symptoms and is most severe among those with co-occurring PTSD and insomnia. Fear of sleep may merit targeted treatment in first responders.\u0000","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138618978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma and CSF Proteomic Signatures of Acutely Sleep-Deprived Humans: An Exploratory Study 急性睡眠剥夺人类血浆和脑脊液蛋白质组学特征:一项探索性研究
SLEEP Advances Pub Date : 2023-11-14 DOI: 10.1093/sleepadvances/zpad047
Ana Vaquer-Alicea, Jinsheng Yu, Haiyan Liu, Brendan P Lucey
{"title":"Plasma and CSF Proteomic Signatures of Acutely Sleep-Deprived Humans: An Exploratory Study","authors":"Ana Vaquer-Alicea, Jinsheng Yu, Haiyan Liu, Brendan P Lucey","doi":"10.1093/sleepadvances/zpad047","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad047","url":null,"abstract":"Abstract Study objectives Acute sleep deprivation affects both central and peripheral biological processes. Prior research has mainly focused on specific proteins or biological pathways that are dysregulated in the setting of sustained wakefulness. This exploratory study aimed to provide a comprehensive view of the biological processes and proteins impacted by acute sleep deprivation in both plasma and cerebrospinal fluid (CSF). Methods We collected plasma and CSF from human participants during one night of sleep deprivation and control normal sleep conditions. 1300 proteins were measured at hour 0 and hour 24 using a high-scale aptamer-based proteomics platform (SOMAscan) and a systematic biological database tool (Metascape) was used to reveal altered biological pathways. Results Acute sleep deprivation decreased the number of upregulated and downregulated biological pathways and proteins in plasma but increased upregulated and downregulated biological pathways and proteins in CSF. Predominantly affected proteins and pathways were associated with immune response, inflammation, phosphorylation, membrane signaling, cell-cell adhesion, and extracellular matrix organization. Conclusions The identified modifications across biofluids adds to evidence that acute sleep deprivation has important impacts on biological pathways and proteins that can negatively affect human health. As a hypothesis-driving study, these findings may help with the exploration of novel mechanisms that mediate sleep loss and associated conditions, drive the discovery of new sleep loss biomarkers, and ultimately aid in the identification of new targets for intervention to human diseases.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"4 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134991479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Life Will Never Be the Same”: A Qualitative Analysis of the Impact of COVID-19 on Adults with a History of Insomnia “生活将永远不一样”:新冠肺炎对有失眠史的成年人影响的定性分析
SLEEP Advances Pub Date : 2023-11-13 DOI: 10.1093/sleepadvances/zpad046
Ashley Redding, Sara Santarossa, Chaewon Sagong, David A Kalmbach, Christopher L Drake, Melynda D Casement, Philip Cheng
{"title":"“Life Will Never Be the Same”: A Qualitative Analysis of the Impact of COVID-19 on Adults with a History of Insomnia","authors":"Ashley Redding, Sara Santarossa, Chaewon Sagong, David A Kalmbach, Christopher L Drake, Melynda D Casement, Philip Cheng","doi":"10.1093/sleepadvances/zpad046","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad046","url":null,"abstract":"Abstract Study Objectives To utilize qualitative data analysis to enrich our understanding of the impact of COVID-19 on those with a pre-pandemic history of insomnia. Methods The sample included 208 participants who completed the Coronavirus Impact Scale in April and May 2020. A content analysis was used to analyze responses to a free response item “Please tell us about any other ways the coronavirus has impacted your life” (n = 175), using a combination of inductive and deductive coding. Results Both negative and positive themes emerged, including altered access to health care, negative financial impacts, and various emotions surrounding COVID-19. Some shared “silver linings” such as having more time for physical activity and deepening familial connections. Conclusions This analysis provides novel insight into the shared concerns and lived experiences of those with a history of insomnia. Understanding these unique stressors can enable healthcare professionals to better anticipate the needs of this population, as well as learn to navigate future stressful events.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"52 20","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A conserved role for frizzled in sleep architecture 卷曲在睡眠结构中的保守作用
SLEEP Advances Pub Date : 2023-11-11 DOI: 10.1093/sleepadvances/zpad045
Nicholas R Gessner, Morteza Peiravi, Fan Zhang, Shemsiya Yimam, Danielle Springer, Susan T Harbison
{"title":"A conserved role for <i>frizzled</i> in sleep architecture","authors":"Nicholas R Gessner, Morteza Peiravi, Fan Zhang, Shemsiya Yimam, Danielle Springer, Susan T Harbison","doi":"10.1093/sleepadvances/zpad045","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad045","url":null,"abstract":"Abstract Previous studies of natural variants in Drosophila melanogaster implicated the Wnt signaling receptor frizzled in sleep. Given that the Wnt signaling pathway is highly conserved across species, we hypothesized that frizzled class receptor 1 (Fzd1), the murine homolog of frizzled, would also have a role in sleep. Using a CRISPR transgenic approach, we removed most of the Fzd1 coding region from C57BL/6N mice. We used a video assay to measure sleep characteristics in Fzd1-deficient mice. As Wnt signaling is known to affect visuospatial memory, we also examined the impact of the deletion on learning and memory using the Novel Object Recognition (NOR) paradigm. Fzd1-deficient mice had altered sleep compared to littermate controls. The mice did not respond differently to the NOR paradigm compared to controls but did display anxiety-like behavior. Our strategy demonstrates that the study of natural variation in Drosophila sleep translates into candidate genes for sleep in vertebrate species such as the mouse.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"21 14","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135086521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening for Obstructive Sleep Apnea in Patients with Cancer – a Machine Learning Approach 癌症患者的阻塞性睡眠呼吸暂停筛查——一种机器学习方法
SLEEP Advances Pub Date : 2023-10-31 DOI: 10.1093/sleepadvances/zpad042
Karen A Wong, Ankita Paul, Paige Fuentes, Diane C Lim, Anup Das, Miranda Tan
{"title":"Screening for Obstructive Sleep Apnea in Patients with Cancer – a Machine Learning Approach","authors":"Karen A Wong, Ankita Paul, Paige Fuentes, Diane C Lim, Anup Das, Miranda Tan","doi":"10.1093/sleepadvances/zpad042","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad042","url":null,"abstract":"Abstract Background Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder associated with daytime sleepiness, fatigue, and increased all-cause mortality risk in cancer patients. Existing screening tools for OSA do not account for the interaction of cancer-related features that may increase OSA risk. Study Design and Methods This is a retrospective study of cancer patients at a single tertiary cancer institution who underwent home sleep apnea test (HSAT) to evaluate for OSA. Unsupervised machine learning (ML) was used to reduce the dimensions and extract significant features associated with OSA. ML classifiers were applied to principal components and model hyperparameters were optimized using k-fold cross validation. Training models for OSA were subsequently tested and compared with the STOP-Bang questionnaire on a prospective unseen test set of patients who underwent an HSAT. Results From a training dataset of 249 patients, kernel principal component analysis extracted 8 components through dimension reduction to explain the maximum variance with OSA at 98%. Predictors of OSA were smoking, asthma, chronic kidney disease, STOP-Bang score, race, diabetes, radiation to head/neck/thorax (RT-HNT), type of cancer, and cancer metastases. Of the ML models, PCA+RF had the highest sensitivity (96.8%), specificity (92.3%), negative predictive value (92%), F1 score (0.93), and ROC-AUC score (0.88). The PCA+RF screening algorithm also performed better than the STOP-Bang questionnaire alone when tested on a prospective unseen test set. Conclusion The PCA+RF ML model had the highest accuracy in screening for OSA in cancer patients. History of RT-HNT, cancer metastases, and type of cancer were identified as cancer-related risk factors for OSA.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"72 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135927973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P090 How do Australian Shiftworkers and Non-Shiftworkers Prioritise Sleep, Diet, and Physical activity? 澳大利亚轮班工人和非轮班工人如何优先考虑睡眠、饮食和体育活动?
SLEEP Advances Pub Date : 2023-10-01 DOI: 10.1093/sleepadvances/zpad035.175
C Gupta, M Duncan, S Ferguson, A Rebar, C Vandelanotte, M Sprajcer, S Khalesi, L Booker, C Rampling, G Rigney, G Vincent
{"title":"P090 How do Australian Shiftworkers and Non-Shiftworkers Prioritise Sleep, Diet, and Physical activity?","authors":"C Gupta, M Duncan, S Ferguson, A Rebar, C Vandelanotte, M Sprajcer, S Khalesi, L Booker, C Rampling, G Rigney, G Vincent","doi":"10.1093/sleepadvances/zpad035.175","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.175","url":null,"abstract":"Abstract Background Increasing engagement with sleep, diet, and physical activity (PA) is critical for populations who are at higher risk of poor health, such as shiftworkers. To increase engagement in sleep, diet and PA, it is critical to first understand which of these behaviours Australians currently prioritise and whether this prioritisation relates to actual behaviour. Therefore, this study aimed to investigate how Australians prioritise sleep, diet and PA. Methods A cohort of 1151 Australian adults (54% female, aged 18-65 years) completed a phone interview, and a cohort of 588 Australian shiftwork-only adults (76% female, 18-72 years) completed an online survey. All participants were asked which health behaviour (sleep, diet or PA) they prioritised. Behavioural correlates of sleep, diet, and PA, and questions on shiftwork experience were also collected. Results Diet was prioritised by the adults (49%), whereas sleep was prioritised by the shiftwork-only sample (68%). Multinomial logistic regressions revealed that adults who prioritised diet were significantly more likely to report less fast-food consumption (p&amp;lt;0.002) and more fruit consumption (p&amp;lt;0.002) compared to those that prioritised sleep. For the shiftwork-only sample, those with 16-30 years of shiftwork experience were significantly more likely to prioritise sleep compared to diet (p&amp;lt;0.05). Conclusions While prioritising diet was associated with healthier diet behaviour in Australian adults, overall, across both cohorts, behaviour prioritisation did not relate to actual behaviour. This suggests that there are factors other than behaviour prioritisation that influence engagement in healthy behaviours. These factors, such as workplace barriers, should be the focus of future research.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136052641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
O019 Sleep spindles are reduced in children with Down syndrome and sleep disordered breathing [019]患有唐氏综合症和睡眠呼吸障碍的儿童睡眠纺锤波减少
SLEEP Advances Pub Date : 2023-10-01 DOI: 10.1093/sleepadvances/zpad035.019
M Shetty, B Tan, M Davey, G Nixon, L Walter, R Horne
{"title":"O019 Sleep spindles are reduced in children with Down syndrome and sleep disordered breathing","authors":"M Shetty, B Tan, M Davey, G Nixon, L Walter, R Horne","doi":"10.1093/sleepadvances/zpad035.019","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.019","url":null,"abstract":"Abstract Background Children with Down syndrome (DS) are at increased risk of sleep disordered breathing (SDB), which is associated with sleep disruption affecting daytime functioning. There is growing evidence that sleep spindles may serve as a sensitive marker of sleep quality. We investigated sleep spindle activity and its relationship with daytime functioning in children with DS compared to typically developing (TD) children matched for SDB severity. Methods Children with DS and SDB (n=44) and TD children matched for age, sex and SDB severity underwent overnight polysomnography. Fast or Slow sleep spindles were identified manually during N2 and N3 sleep. Spindle activity was characterised as spindle number, density (number of spindles/h) and intensity (density x average duration) on central (C) and frontal (F) electrodes. Parents completed the Child Behavior Checklist (CBCL) and OSA-18 questionnaires. Results Spindle number, density, and intensity were lower in the children with DS compared to TD children for F Slow and F Slow&amp;Fast spindles combined (p&amp;lt;0.001 for all). In children with DS, there were no correlations between the density of any spindle type and subscales of the CBCL, however, spindle number, density and intensity for C Fast and C Slow&amp;Fast were negatively correlated with OSA-18 emotional symptoms and caregiver concerns and C Fast number, density and intensity were also negatively correlated with daytime function and total problems. Conclusions The reduced spindle activity in the children with DS, indicates sleep micro-architecture is disrupted and this disruption may underpin the negative effects of SDB on quality of life and behaviour.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P085 Early Childhood and Adolescent Predictors of Sleep Problems and Sleep Disorders in Adulthood: A Systematic Review of Longitudinal Observational Studies 儿童早期和青少年睡眠问题和成年期睡眠障碍的预测因素:纵向观察研究的系统回顾
SLEEP Advances Pub Date : 2023-10-01 DOI: 10.1093/sleepadvances/zpad035.170
G Desalegn, G Rawson, Y Melaku, Z Abitew, P Eastwood, A Reynolds
{"title":"P085 Early Childhood and Adolescent Predictors of Sleep Problems and Sleep Disorders in Adulthood: A Systematic Review of Longitudinal Observational Studies","authors":"G Desalegn, G Rawson, Y Melaku, Z Abitew, P Eastwood, A Reynolds","doi":"10.1093/sleepadvances/zpad035.170","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.170","url":null,"abstract":"Abstract Background By middle-age, 43% of Australian adults live with a clinical sleep disorder. Sleep disorders are linked to chronic illnesses which are a leading cause of premature mortality. The aim of this review was to identify, appraise and synthesise evidence from longitudinal observational studies to clarify childhood and adolescence risk factors associated with sleep disorders in adulthood. Method Four databases (Web of Science, Medline, SCOPUS, and PSYCINFO) were searched using predefined inclusion and exclusion criteria for studies which were longitudinal, including at least one risk factor measured before 18 years of age, and an assessment of sleep problems or disorders in adulthood. This study was registered with PROSPERO (CRD42022301342). Result A total of 13,712 studies were screened, with 51 studies meeting criteria for data extraction. Sleep problems in childhood (n=9), childhood mental health (n=7), family environment (n= 2), adverse childhood experience (n=5), and lifestyle factors (n=9) were reported to be associated with sleep problems in adulthood. However most studies (n=30) only considered one or two measurements time points in childhood or adolescence as a predictor of adult sleep problems, and the age of sleep problem measurement in adulthood varied considerably (18 – 42 years). Further, heterogeneous sleep outcomes were reported across the studies, making quantitative synthesis of the data extremely challenging. Discussion Sleep problems in adulthood may be a result of cumulative risk factors in early childhood and adolescence. Consideration of childhood and adolescent trajectories are needed to better understand the biopsychosocial predictors of sleep problems in adulthood.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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