SLEEP Advances最新文献_第4页

Prevalence of Central Sleep Apnea among Veterans and Response Rate to Continuous Positive Airway Pressure Therapy 退伍军人中中枢性睡眠呼吸暂停的患病率和对持续气道正压疗法的反应率

SLEEP Advances Pub Date : 2024-02-05 DOI: 10.1093/sleepadvances/zpae011

Nesrine Adly Ibrahim, Abdulghani Sankari, A. Aldwaikat, Nishtha Pandya, S. Chowdhuri, A. Salloum, Jennifer L Martin, S. Zeineddine, M. S. Badr

{"title":"Prevalence of Central Sleep Apnea among Veterans and Response Rate to Continuous Positive Airway Pressure Therapy","authors":"Nesrine Adly Ibrahim, Abdulghani Sankari, A. Aldwaikat, Nishtha Pandya, S. Chowdhuri, A. Salloum, Jennifer L Martin, S. Zeineddine, M. S. Badr","doi":"10.1093/sleepadvances/zpae011","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae011","url":null,"abstract":"\u0000 \u0000 \u0000 Sleep-disordered breathing (SDB) is common in the Veteran population. In this retrospective study, we investigated the prevalence of comorbid central and obstructive SDB and the response rate to PAP among Veterans.\u0000 \u0000 \u0000 \u0000 Veterans were screened from a single VA medical center who had a polysomnography (PSG) study from 2017-2021 to ascertain the presence, severity, and type of SDB by measuring the Apnea-Hypopnea Index (AHI) and Central Apnea Index (CAI). Patients were excluded if they did not have complete studies (diagnostic and PAP titration studies). The inclusion criteria for these analyses were central sleep apnea (CSA) defined as AHI ≥ 10 events/hour and CAI ≥ 5 events/ hour. Diagnostic “CSA only” was defined as AHI ≥ 10 events/ hour and CAI ≥ 50% of AHI. “OSA only” was defined if AHI≥ 10 events/ hour and CAI < 5 events/ hour. Comorbid central and obstructive sleep apnea (COSA) was defined if AHI≥ 10 events/ hour and CAI > 5 events/ hour but <50% of AHI. The responsiveness to PAP therapy was determined based on the CAI < 5 events/h on the titration study.\u0000 \u0000 \u0000 \u0000 A total of 90 patients met the inclusion criteria and from those 64 Veterans were found to have COSA (71%), 18 (20%) were CSA only, and 8 (9%) were OSA only. A total of 22 (24.4%) Veterans diagnosed with CSA or COSA were responsive to PAP therapy. Sixty days after treatment initiation, both responsive and nonresponsive groups had significant decreases in AHI and CAI (p<0.05).\u0000 \u0000 \u0000 \u0000 Comorbid central and obstructive SDB is common among Veterans. The response to PAP therapy is suboptimal but improves over time.\u0000","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139865510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving Adolescent Sleep in Long-Term Juvenile Correctional Settings: Case Examples with Clinical, Research, and Policy Implications 改善长期青少年管教环境中的青少年睡眠：具有临床、研究和政策影响的案例

SLEEP Advances Pub Date : 2024-02-04 DOI: 10.1093/sleepadvances/zpae006

Barbara Robles-Ramamurthy, Saadia Zaki, Jessica Sandoval, Anish R Dube, Steven Hlozek, Lisa R Fortuna, Ariel A Williamson

{"title":"Improving Adolescent Sleep in Long-Term Juvenile Correctional Settings: Case Examples with Clinical, Research, and Policy Implications","authors":"Barbara Robles-Ramamurthy, Saadia Zaki, Jessica Sandoval, Anish R Dube, Steven Hlozek, Lisa R Fortuna, Ariel A Williamson","doi":"10.1093/sleepadvances/zpae006","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae006","url":null,"abstract":"\u0000 Poor sleep during adolescence is a public health concern that may be especially important to address among youth in juvenile correctional facilities, who tend to experience greater mental health challenges, substance use disorders, and traumatic stress exposure. However, evidence for addressing sleep in correctional settings is limited. Using de-identified composite clinical cases, this paper describes challenges and opportunities for addressing sleep disorders (i.e., insomnia) and promoting sleep health (i.e., improving duration, regularity, and behaviors) among adolescents in long-term juvenile correctional facilities. These clinical cases highlight common presenting problems and underscore the need for integrated sleep and mental health interventions as well as adaptations to enhance feasibility and efficacy of behavioral sleep treatment and sleep health promotion in juvenile correctional contexts. We conclude by summarizing clinical, research, and policy implications for addressing adolescent sleep problems and promoting sleep health and wellbeing in these contexts.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"2012 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139807386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving Adolescent Sleep in Long-Term Juvenile Correctional Settings: Case Examples with Clinical, Research, and Policy Implications 改善长期青少年管教环境中的青少年睡眠：具有临床、研究和政策影响的案例

SLEEP Advances Pub Date : 2024-02-04 DOI: 10.1093/sleepadvances/zpae006

Barbara Robles-Ramamurthy, Saadia Zaki, Jessica Sandoval, Anish R Dube, Steven Hlozek, Lisa R Fortuna, Ariel A Williamson

{"title":"Improving Adolescent Sleep in Long-Term Juvenile Correctional Settings: Case Examples with Clinical, Research, and Policy Implications","authors":"Barbara Robles-Ramamurthy, Saadia Zaki, Jessica Sandoval, Anish R Dube, Steven Hlozek, Lisa R Fortuna, Ariel A Williamson","doi":"10.1093/sleepadvances/zpae006","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae006","url":null,"abstract":"\u0000 Poor sleep during adolescence is a public health concern that may be especially important to address among youth in juvenile correctional facilities, who tend to experience greater mental health challenges, substance use disorders, and traumatic stress exposure. However, evidence for addressing sleep in correctional settings is limited. Using de-identified composite clinical cases, this paper describes challenges and opportunities for addressing sleep disorders (i.e., insomnia) and promoting sleep health (i.e., improving duration, regularity, and behaviors) among adolescents in long-term juvenile correctional facilities. These clinical cases highlight common presenting problems and underscore the need for integrated sleep and mental health interventions as well as adaptations to enhance feasibility and efficacy of behavioral sleep treatment and sleep health promotion in juvenile correctional contexts. We conclude by summarizing clinical, research, and policy implications for addressing adolescent sleep problems and promoting sleep health and wellbeing in these contexts.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"12 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139867018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association between Timing of Dietary Macronutrient and Sodium Consumption and Sleep Duration and Quality 膳食中摄入宏量营养素和钠的时间与睡眠时间和质量之间的关系

SLEEP Advances Pub Date : 2024-01-23 DOI: 10.1093/sleepadvances/zpae007

V. A. Ansu Baidoo, S. Alexandria, Phyllis C Zee, Kristen L. Knutson

{"title":"The Association between Timing of Dietary Macronutrient and Sodium Consumption and Sleep Duration and Quality","authors":"V. A. Ansu Baidoo, S. Alexandria, Phyllis C Zee, Kristen L. Knutson","doi":"10.1093/sleepadvances/zpae007","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae007","url":null,"abstract":"\u0000 \u0000 \u0000 The objective of this study was to examine the association between the timing of dietary macronutrients and sodium intake and sleep quantity and quality\u0000 \u0000 \u0000 \u0000 This was a cross-sectional study that included 34 adults between 21 and 50 years of age. The main outcome measures were objective sleep measures assessed from 3 nights of wrist actigraphy including sleep duration, fragmentation, and wake after sleep onset (WASO), and one night of polysomnography (PSG), including rapid eye movement (REM) sleep, non-REM stage 2 (N2), stage 3 (N3), and WASO. Multiple linear regression models and linear mixed models were used to estimate the associations between sleep measures and dietary measures (carbohydrates, fats, saturated fats, proteins, and sodium). Dietary timing was examined in two ways: (1) the average amount of each nutrient consumed within three hours of sleep start, and (2) the interval between the final intake of each nutrient and sleep.\u0000 \u0000 \u0000 \u0000 Average fat intake within 3 hours of sleep was associated with greater WASO from PSG (β=4.48, p=0.01). No other associations were found between the macronutrients or sodium intake (p>0.05) within 3 hours of sleep and the sleep parameters from PSG or actigraphy. Similarly, no associations were found between any of the PSG or actigraphy sleep measures and the interval between final nutrient intakes and sleep with sleep duration.\u0000 \u0000 \u0000 \u0000 The study suggests that greater fat but not carbohydrate, protein, saturated fat, or sodium intake close to sleep may be associated with greater sleep disruption, however, no other associations were observed.\u0000","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"115 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139605618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obstructive sleep apnea, nocturnal hypoxemia and retinal microvasculature: The Atherosclerosis Risk in Communities Study 阻塞性睡眠呼吸暂停、夜间低氧血症和视网膜微血管：社区动脉粥样硬化风险研究

SLEEP Advances Pub Date : 2024-01-20 DOI: 10.1093/sleepadvances/zpae004

Nathan Hoeft, Kelsie M. Full, Jeffrey R Misialek, K. Lakshminarayan, Srishti Shrestha, Jennifer A Deal, P. Lutsey

{"title":"Obstructive sleep apnea, nocturnal hypoxemia and retinal microvasculature: The Atherosclerosis Risk in Communities Study","authors":"Nathan Hoeft, Kelsie M. Full, Jeffrey R Misialek, K. Lakshminarayan, Srishti Shrestha, Jennifer A Deal, P. Lutsey","doi":"10.1093/sleepadvances/zpae004","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae004","url":null,"abstract":"\u0000 \u0000 \u0000 Retinal microvascular pathology (RMP) and obstructive sleep apnea (OSA) are both cardiovascular disease risk factors. Limited data exists on their interrelationship. We tested the hypotheses that OSA and nocturnal hypoxemia would be associated with retinal microvascular pathology and vessel calibers.\u0000 \u0000 \u0000 \u0000 We conducted a quasi-cross-sectional analysis of 1,625 participants in the Atherosclerosis Risk in Communities (ARIC) Sleep Heart Health Study (SHHS). Participants completed in-home polysomnography monitoring (1996-1998) and were categorized by OSA severity (apnea-hypopnea index (AHI): <5, 5-14.9, ≥15) and proportion of total sleep time with oxygen saturation <90% (T90). Retinal photography (1993-1995) was used to assess RMP and measure vascular diameters (central retinal arteriolar and venular equivalent; CRAE and CRVE). Logistic and linear models were adjusted for demographics, behaviors and BMI.\u0000 \u0000 \u0000 \u0000 Of the participants, 19% had OSA (AHI>15) and 4% had RMP. Severe OSA was not associated with RMP [OR (95% CI): 1.08 (0.49-2.38)] or CRAE in adjusted models. OSA severity showed a positive linear relationship with CRVE; adjusted mean CRVE for those with OSA was 195.8 μm compared to 193.2 μm for those without OSA (Ptrend = 0.03). T90 was strongly associated with CRVE, but not with RMP or CRAE. Adjusted mean CRVE for T90 ≥5% was 199.0 and 192.9 for T90 <1% (Ptrend <0.0001).\u0000 \u0000 \u0000 \u0000 OSA and T90 were not associated with RMP or CRAE. However, both OSA and T90 ≥5% were associated with wider venules, which may be early and indicative changes of increased inflammation and future risk of stroke and CHD.\u0000","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"12 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139610630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treating insomnia in people who are incarcerated: a feasibility study of a multi-component treatment pathway 治疗被监禁者的失眠症：多成分治疗路径的可行性研究

SLEEP Advances Pub Date : 2024-01-20 DOI: 10.1093/sleepadvances/zpae003

L. Dewa, B. Thibaut, Natalie Pattison, Sean James Campbell, Thomas Woodcock, Paul Aylin, Stephanie Archer

{"title":"Treating insomnia in people who are incarcerated: a feasibility study of a multi-component treatment pathway","authors":"L. Dewa, B. Thibaut, Natalie Pattison, Sean James Campbell, Thomas Woodcock, Paul Aylin, Stephanie Archer","doi":"10.1093/sleepadvances/zpae003","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae003","url":null,"abstract":"\u0000 Around 60% of people who are incarcerated have insomnia; 6-10 times more prevalent than the general population. Yet, there is no standardised, evidence-based approach to insomnia treatment in prison. We assessed the feasibility of a treatment pathway for insomnia in a high-secure prison to inform a future randomised controlled trial (RCT) and initial efficacy data for sleep and mental health outcomes. We used a within-subjects pre-post design. The stepped-care pathway included: self-management with peer support, environmental aids, and cognitive behavioural therapy for insomnia (CBTi). Assessment measures for insomnia, wellbeing, mood, anxiety, suicidality, overall health, sleepiness, fatigue, and cognitive functioning were administered at baseline and pathway exit. Feasibility criteria included eligibility to participate, CBTi uptake and assessment completion. Forty-two adult males who are incarcerated were approached of which 95.2% were eligible. Of those deemed eligible, most participated (36/40, 90.0%). Most who completed baseline completed post-assessments (28/36, 77.8%) and of these, most showed improvements in their subjective sleep (27/28, 96.4%). Large reductions were found from pre- to post-treatment in insomnia severity (d=-1.81, 95% CIs 8.3 to 12.9) and 57.0% reported no clinically significant insomnia symptoms at post-assessment. There was no overall change in actigraphy-measured sleep. Large treatment benefits were found for depression, anxiety, wellbeing, and cognitive functioning, with a medium benefit on suicidal ideation. The treatment pathway for insomnia in prison was feasible and may be an effective treatment for insomnia in people who are incarcerated, with additional promising benefits for mental health. A pragmatic RCT across different prison populations is warranted.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"7 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139610978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shorter total sleep time is associated with lower CD4+/CD8+ T cell ratios in virally suppressed men with HIV 总睡眠时间较短与病毒已被抑制的男性艾滋病毒感染者 CD4+/CD8+ T 细胞比率较低有关

SLEEP Advances Pub Date : 2024-01-17 DOI: 10.1093/sleepadvances/zpae001

P. Borker, B. Macatangay, Joseph B Margolick, Naresh M Punjabi, Charles R. Rinaldo, Valentina Stosor, Joshua Hyong-Jin Cho, Heather McKay, Sanjay R Patel

{"title":"Shorter total sleep time is associated with lower CD4+/CD8+ T cell ratios in virally suppressed men with HIV","authors":"P. Borker, B. Macatangay, Joseph B Margolick, Naresh M Punjabi, Charles R. Rinaldo, Valentina Stosor, Joshua Hyong-Jin Cho, Heather McKay, Sanjay R Patel","doi":"10.1093/sleepadvances/zpae001","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae001","url":null,"abstract":"\u0000 \u0000 \u0000 Although poor sleep quality is associated with lower CD4+ T cell counts among people living with HIV (PLWH), the association between objective sleep metrics and T lymphocyte subset counts is unknown. We evaluated the association between polysomnography (PSG) derived sleep metrics and T lymphocyte subpopulations in a cohort of men living with HIV.\u0000 \u0000 \u0000 \u0000 Virally suppressed men living with HIV participating in the Multicenter AIDS Cohort Study underwent home overnight PSG. We assessed the association of PSG parameters with CD4+ and CD8+ T cell counts and the CD4+/CD8+ T cell ratio.\u0000 \u0000 \u0000 \u0000 Overall, 289 men with mean (±SD) age 55.3 ±11.3 years and mean CD4+ T cell count 730 ±308 cells/mm3 were evaluated. Total sleep time (TST) was significantly associated with CD8+ but not CD4+ T cell counts. After adjusting for age, race, depressive symptoms, antidepressant use, and non-nucleoside reverse transcriptase inhibitors use, every hour of shorter TST was associated with an additional 33 circulating CD8+ T cells/mm3 (p=0.05) and a 5.6% (p=0.0007) decline in CD4+/CD8+ T cell ratio. In adjusted models, every hour of shorter REM sleep was associated with an additional 113 CD8+ T cells/mm3 (p=0.02) and a 15.1% lower CD4+/CD8+ T cell ratio (p=0.006). In contrast, measures of sleep efficiency and sleep-disordered breathing were not associated with differences in T lymphocyte subpopulations.\u0000 \u0000 \u0000 \u0000 Our findings suggest that shorter TST and REM sleep durations are associated with differences in T lymphocyte subpopulations among men living with HIV. Addressing sleep may reflect a novel opportunity to improve immune function in PLWH.\u0000","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"18 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of sleep disruption on cognitive function in patients with post-acute sequelae of SARS-CoV-2 infection: Initial findings from a Neuro-COVID-19 clinic 睡眠中断对 SARS-CoV-2 感染后急性后遗症患者认知功能的影响：神经-COVID-19 诊所的初步发现

SLEEP Advances Pub Date : 2024-01-12 DOI: 10.1093/sleepadvances/zpae002

K. Reid, Louis T Ingram, M. Jimenez, Z. Orban, Sabra M. Abbott, Daniela Grimaldi, Kristen L. Knutson, Phyllis C Zee, Igor Koralnik, Mathew B Maas

{"title":"Impact of sleep disruption on cognitive function in patients with post-acute sequelae of SARS-CoV-2 infection: Initial findings from a Neuro-COVID-19 clinic","authors":"K. Reid, Louis T Ingram, M. Jimenez, Z. Orban, Sabra M. Abbott, Daniela Grimaldi, Kristen L. Knutson, Phyllis C Zee, Igor Koralnik, Mathew B Maas","doi":"10.1093/sleepadvances/zpae002","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae002","url":null,"abstract":"\u0000 \u0000 \u0000 Fatigue, brain fog and sleep disturbance are among the most common symptoms of post-acute sequelae of SARS-CoV-2 infection (PASC). We sought to determine the impact of sleep disruption on cognition and quality-of-life in patients with neurologic manifestations of PASC (Neuro-PASC).\u0000 \u0000 \u0000 \u0000 Thirty-nine patients were recruited from Neuro-COVID-19 clinic. Mean age was 48.1 years, 71.8% were female, and 82% were never hospitalized for COVID-19. Patients were evaluated via clinical assessment, quality-of-life measures in domains of cognitive function, fatigue, sleep disturbance, anxiety, and depression, NIH toolbox cognitive tests, and 7 days of wrist actigraphy.\u0000 \u0000 \u0000 \u0000 The median number of neurologic symptoms attributed to PASC was 6, with brain fog being the most common in 89.7%. Regarding non-neurologic symptoms, 94.9% complained of fatigue and 74.4% of insomnia. Patients reported significant impairment in all quality-of-life domains and performed worse in a task of attention compared to a normative US population. Actigraphy showed Neuro-PASC patients had lower sleep efficiency, longer sleep latency (both p<0.001) and later sleep midpoint (p=0.039) compared to 71 age-matched healthy controls with no PASC history. Self-reported cognitive symptoms correlated with severity of fatigue (p<0.001), anxiety (p=0.05), and depression (p<0.01). Objective evidence of sleep disruption measured by wakefulness after sleep onset, sleep efficiency and latency were associated with decreased performance in attention and processing speed.\u0000 \u0000 \u0000 \u0000 Prospective studies including larger populations of patients are needed to fully determine the interplay of sleep disruption on the cognitive function and quality of life of patients with PASC.\u0000","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139624165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice 富氢水可改善小鼠的睡眠巩固并增强前脑神经元的激活能力

SLEEP Advances Pub Date : 2023-12-30 DOI: 10.1093/sleepadvances/zpad057

S. Vincent, M. Madani, D. Dikeman, K. Golden, N. Crocker, C. Jackson, S. Wimmer, M. Dover, A. Tucker, C. A. Ghiani, C. S. Colwell, T. W. LeBaron, A. Tarnava, K. Paul

{"title":"Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice","authors":"S. Vincent, M. Madani, D. Dikeman, K. Golden, N. Crocker, C. Jackson, S. Wimmer, M. Dover, A. Tucker, C. A. Ghiani, C. S. Colwell, T. W. LeBaron, A. Tarnava, K. Paul","doi":"10.1093/sleepadvances/zpad057","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad057","url":null,"abstract":"Sleep loss contributes to various health issues and impairs neurological function. Molecular hydrogen has recently gained popularity as a non-toxic ergogenic and health promoter. The effect of molecular hydrogen on sleep and sleep-related neural systems remains unexplored. This study investigates the impact of hydrogen-rich water (HRW) on sleep behavior and neuronal activation in sleep-deprived mice. Adult C57BL/6J mice were implanted with electroencephalography (EEG) and electromyography (EMG) recording electrodes and given HRW (0.7 -1.4 mM) or regular water for 7 days ad libitum. Sleep-wake cycles were recorded under baseline conditions and after acute sleep loss. Neuronal activation in sleep- and wake-related regions was assessed using cFos immunostaining. HRW increased sleep consolidation in undisturbed mice and increased non-rapid eye movement (NREM) and rapid-eye movement (REM) sleep amount in sleep-deprived mice. HRW also decreased the average amount of time for mice to fall asleep after light onset. Neuronal activation in the lateral septum, medial septum, ventrolateral preoptic area, and median preoptic area was significantly altered in all mice treated with HRW. HRW improves sleep consolidation and increases neuronal activation in sleep-related brain regions. It may serve as a simple, effective treatment to improve recovery after sleep loss.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139140877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Night-time Sleep Duration and Postpartum Weight Retention in Primiparous Women 初产妇夜间睡眠时间与产后体重潴留

SLEEP Advances Pub Date : 2023-12-27 DOI: 10.1093/sleepadvances/zpad056

Jeanna T Ryan, Heather Day, Marlene J Egger, Jiqiang Wu, Christopher M Depner, Janet M Shaw

{"title":"Night-time Sleep Duration and Postpartum Weight Retention in Primiparous Women","authors":"Jeanna T Ryan, Heather Day, Marlene J Egger, Jiqiang Wu, Christopher M Depner, Janet M Shaw","doi":"10.1093/sleepadvances/zpad056","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad056","url":null,"abstract":"Approximately 75% of women weigh more at 1-year postpartum than pre-pregnancy. More than 47% retain >10 lbs at 1-year postpartum, which is associated with adverse health outcomes for mother and child. Disturbed sleep may contribute to risk of postpartum weight retention (PWR) as short sleep duration is associated with increased risk of obesity. Thus, we investigated whether night-time sleep duration is associated with risk for excessive PWR. We also explored night-time sleep duration and change in postpartum waist circumference. This is an ancillary analysis from a prospective cohort study. Participants were healthy primiparous adults with a singleton birth. Excessive PWR at 1-year postpartum was defined as ≥7% of pre-pregnancy weight. Log-binomial and linear regression assessed associations between night-time sleep duration at 6 months postpartum and PWR at 1-year postpartum. Linear regression assessed association between night-time sleep duration and change in postpartum waist circumference. Mean age of participants (N=467) was 29.51 (SD±4.78) years. Night-time sleep duration by actigraphy or self-report was not associated with risk for excessive PWR (Risk Ratio 0.96, [95%CI 0.87-1.06]; Risk Ratio 0.95 [95%CI 0.83-1.07], respectively) or change in waist circumference. Night-time sleep duration at 6 months postpartum was not associated with PWR at 1-year postpartum. Mixed findings among our results and previous research could be due to our focus on night-time sleep, and differences in sleep measurement methods and timeframes across studies. More comprehensively assessing sleep, including multiple sleep dimensions, may help advance our understanding of potential links between sleep and PWR.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"58 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0