Skin Appendage Disorders最新文献_第9页

Nail Supplements: When, How, and Why? 指甲补充剂：何时，如何，为什么？

IF 1.4

Skin Appendage Disorders Pub Date : 2025-04-01 Epub Date: 2024-09-26 DOI: 10.1159/000541048

Ines Zaraa, Bertrand Richert

引用次数: 0

The First Colombian Patient with CDH3-Related Hypotrichosis with Juvenile Macular Dystrophy. 哥伦比亚首位cdh3相关性毛少症伴幼年黄斑营养不良患者

IF 1.4

Skin Appendage Disorders Pub Date : 2025-03-28 DOI: 10.1159/000545293

Luis Eduardo Prieto, Diana Marcela Vasquez-Forero, Harry Pachajoa

引用次数: 0

Episodes of Keratitis during Treatment with Baricitinib for Alopecia Areata. Baricitinib治疗斑秃期间角膜炎发作。

IF 1.3

Skin Appendage Disorders Pub Date : 2025-03-28 DOI: 10.1159/000544920

Dorottya Godor, Anastasia Therianou

引用次数: 0

Secondary Intention Healing after Functional Surgery for Melanoma of the Nail Apparatus: Functional, Cosmetic, and Patient Satisfaction Results. 甲器黑色素瘤功能性手术后的二次意向愈合：功能、美容和患者满意度结果。

IF 1.4

Skin Appendage Disorders Pub Date : 2025-03-28 DOI: 10.1159/000545468

Jonathan Stevens, Martín Céspede-Núñez

{"title":"Secondary Intention Healing after Functional Surgery for Melanoma of the Nail Apparatus: Functional, Cosmetic, and Patient Satisfaction Results.","authors":"Jonathan Stevens, Martín Céspede-Núñez","doi":"10.1159/000545468","DOIUrl":"https://doi.org/10.1159/000545468","url":null,"abstract":"Introduction: Functional surgery is the preferred approach for nail melanoma in situ (NMIS) and minimally invasive nail melanoma (MINM, Breslow ≤0.5 mm). Secondary intention healing (SIH) offers an alternative to traditional skin grafting, with favorable cosmetic, functional, and satisfaction outcomes and minimal complications.Methods: Six patients (mean age 54.8 years; 4 SMIS, 2 MISSM) underwent functional surgery with SIH. Healing times (granulation [T1] and re-epithelialization [T2]), complications, and outcomes were assessed at 12 weeks using QUICK-DASH, VBSAS, VAS, satisfaction scores, and DLQI.Results: Mean T1 and T2 were 2.83 and 8.45 weeks, respectively. One patient experienced intense postoperative pain; another had a late nail spike. No hyperpigmentation or recurrences were observed. Outcomes: QUICK-DASH 18.92%; VBSAS 2.8 (12 weeks) and 0.25 (24 weeks); VAS 2; DLQI 2; and satisfaction 9.8/10 (10/10 after amputation discussion).Conclusions: SIH provides an effective alternative to grafting, allowing acceptable healing times, flexibility for margin extension or amputation, and excellent cosmetic, functional, and satisfaction outcomes with minimal complications.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Malignant Hidradenoma of the Scalp: A Rare Case with Diagnostic Challenges and Immunohistochemical Insights. 恶性头皮汗腺瘤：罕见病例诊断挑战和免疫组织化学见解。

IF 1.3

Skin Appendage Disorders Pub Date : 2025-03-24 DOI: 10.1159/000545383

Anuradha Calicut Kini Rao, Rakshatha Nayak, P S M Ameer Ali, Shikha Jayasheelan, Kudurugundi Basavaraju Vatsala

{"title":"Malignant Hidradenoma of the Scalp: A Rare Case with Diagnostic Challenges and Immunohistochemical Insights.","authors":"Anuradha Calicut Kini Rao, Rakshatha Nayak, P S M Ameer Ali, Shikha Jayasheelan, Kudurugundi Basavaraju Vatsala","doi":"10.1159/000545383","DOIUrl":"https://doi.org/10.1159/000545383","url":null,"abstract":"Introduction: Hidradenocarcinoma is an extremely rare and aggressive malignant tumor originating from eccrine sweat glands. It typically presents with nonspecific clinical features, which makes early diagnosis challenging. The tumor is known for its potential for recurrence and metastasis, often complicating management.Case presentation: A 57-year-old male presented with a painless, gradually enlarging swelling on the scalp, which had been present for 2.5 years. Initially suspected to be an infected sebaceous cyst, the lesion was excised. Histopathological analysis revealed malignant hidradenoma, characterized by clear cytoplasm, nuclear pleomorphism, and increased mitotic activity. Immunohistochemical staining showed 22% Ki-67 and 14% p53 expression, confirming malignancy. No metastasis was found.Conclusion: Malignant hidradenoma is a rare and aggressive cutaneous tumor that can be challenging to diagnose due to its nonspecific presentation. Early recognition and wide surgical excision are essential for better prognosis and to prevent recurrence or metastasis.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-6"},"PeriodicalIF":1.3,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two Cases of Scabies Located Exclusively on a Toenail: A Case Report. 两例疥疮仅位于脚趾甲：一个病例报告。

IF 1.3

Skin Appendage Disorders Pub Date : 2025-03-24 DOI: 10.1159/000545326

Stefano Veraldi, Gianluca Nazzaro, Italo Francesco Aromolo, Luigi Valenzano

引用次数: 0

Non-Amputative Digit Preservation Surgery versus Amputation in Nail Unit Melanoma: A Retrospective Study in Mexico and Brazil. 指甲单位黑色素瘤的非截肢手指保留手术与截肢：墨西哥和巴西的回顾性研究。

IF 1.4

Skin Appendage Disorders Pub Date : 2025-03-20 DOI: 10.1159/000544995

Jorge Ocampo-Garza, Adriana G Peña-Romero, Eduardo Bertolli, Mayra A Reyes Soto, Nilton Gioia Di Chiacchio, Francisco A Belfort, Veronica Fonte-Avalos, Nilton Di Chiacchio, Judith Domínguez-Cherit

{"title":"Non-Amputative Digit Preservation Surgery versus Amputation in Nail Unit Melanoma: A Retrospective Study in Mexico and Brazil.","authors":"Jorge Ocampo-Garza, Adriana G Peña-Romero, Eduardo Bertolli, Mayra A Reyes Soto, Nilton Gioia Di Chiacchio, Francisco A Belfort, Veronica Fonte-Avalos, Nilton Di Chiacchio, Judith Domínguez-Cherit","doi":"10.1159/000544995","DOIUrl":"https://doi.org/10.1159/000544995","url":null,"abstract":"Introduction: Nail unit melanoma (NUM) is a rare but aggressive malignancy with historically poor outcomes. Currently, there are no treatment guidelines for NUM.Methods: A retrospective analysis was conducted on patients diagnosed with NUM in Mexico and Brazil. Clinical and histopathological data were reviewed, and outcomes were compared between those who underwent amputation versus digit preservation surgery. Survival rates, recurrence, and functional status were assessed.Results: A total of 75 patients from Mexico (51.9%) and Brazil (48.1%) were evaluated. Clinical and pathological characteristics were similar between both groups. Functional surgery was performed in 40 patients (49.4%), including six with invasive melanomas. The median follow-up was 50.3 months (95% CI: 29.4-71.3, SE: 10.7). Among the 7 patients with invasive melanomas who underwent functional surgery, one experienced a recurrence, and one died from a cerebrovascular accident. The remaining 5 patients are alive and disease-free, with follow-up periods ranging from 1 to 27 months.Conclusions: Non-amputative surgery may be a safe alternative for thin NUMs, reducing amputation-related morbidity. Long-term follow-up and larger studies are needed to confirm guidelines.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermatological Comorbidities Accompanying Rosacea and Their Relationship with Clinical and Demographic Features, Quality of Life, and Systemic Comorbidities: A Retrospective, Case-Controlled, Multicenter Survey. 伴随酒渣鼻的皮肤病合并症及其与临床和人口学特征、生活质量和全身合并症的关系：一项回顾性、病例对照、多中心调查。

IF 1.4

Skin Appendage Disorders Pub Date : 2025-03-20 DOI: 10.1159/000545295

Berna Aksoy, Elif Yıldırım, Ezgi Aktaş, Mualla Polat, Kıymet Handan Kelekci, Mustafa Tosun, Aysun Sikar Aktürk, Ilkin Zindancı, Seniz Duygulu, Emine Çölgeçen, Zehra Asiran Serdar, Ömer Kutlu, Neslihan Fişek İzci, Ayşe Serap Karadağ

{"title":"Dermatological Comorbidities Accompanying Rosacea and Their Relationship with Clinical and Demographic Features, Quality of Life, and Systemic Comorbidities: A Retrospective, Case-Controlled, Multicenter Survey.","authors":"Berna Aksoy, Elif Yıldırım, Ezgi Aktaş, Mualla Polat, Kıymet Handan Kelekci, Mustafa Tosun, Aysun Sikar Aktürk, Ilkin Zindancı, Seniz Duygulu, Emine Çölgeçen, Zehra Asiran Serdar, Ömer Kutlu, Neslihan Fişek İzci, Ayşe Serap Karadağ","doi":"10.1159/000545295","DOIUrl":"https://doi.org/10.1159/000545295","url":null,"abstract":"Introduction: As rosacea patients are generally light-skinned and photosensitized some sun-related skin findings are likely to be observed. This study aimed to determine which dermatological comorbidities accompany rosacea and evaluate their relationship with clinical, demographic, quality-of-life, and systemic comorbidities.Methods: This case-control multicenter study was conducted by the Turkish Society of Dermatology Acne Study Group. Patient demographics, clinical findings, lifestyle data, medical history, and dermatological comorbidities were collected using a structured physician-administered questionnaire. All patients completed the Dermatology Life Quality Index.Results: The study included 922 rosacea patients and 799 controls without rosacea. Rosacea patients had higher dermatological comorbidities than controls. The prevalence of skin comorbidities increased as patient age and duration of rosacea increased. Additionally, these skin comorbidities negatively affected quality of life. Some dermatological comorbidities, especially civatte poikiloderma, had strongest predictive risk (odds ratio ⫺3) of significant systemic comorbidities.Conclusion: Based on the present findings, clinicians should also assess rosacea patients for cutaneous dermatological comorbidities. Presence of skin comorbidities increased as patient age and duration of rosacea increased and might be predictive of systemic comorbidities.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-7"},"PeriodicalIF":1.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scarring Alopecia and Risk of Skin Cancer: A Literature Review. 瘢痕性脱发与皮肤癌风险：文献综述。

IF 1.4

Skin Appendage Disorders Pub Date : 2025-03-20 DOI: 10.1159/000545345

Juwon Lee, Ludovica de Gregorio, Antonella Tosti

{"title":"Scarring Alopecia and Risk of Skin Cancer: A Literature Review.","authors":"Juwon Lee, Ludovica de Gregorio, Antonella Tosti","doi":"10.1159/000545345","DOIUrl":"https://doi.org/10.1159/000545345","url":null,"abstract":"Background: Primary scarring alopecia is characterized by irreversible hair follicle destruction and chronic inflammation, which may create a microenvironment conducive to skin cancer development. Non-melanoma skin cancers (NMSCs), such as squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), are influenced by factors like UV exposure and prolonged inflammation. The link between primary scarring alopecia and increased scalp skin cancer risk remains unclear.Summary: This review analyzed thirteen studies reporting NMSC in primary scarring alopecia subtypes, including lichen planopilaris, discoid lupus erythematosus, folliculitis decalvans, and erosive pustular dermatosis of the scalp. Chronic inflammation, UV exposure, and immunosuppressive therapies were identified as potential contributors to malignancy.Key messages: Primary scarring alopecia may increase susceptibility to SCC and BCC, particularly in areas of prolonged inflammation or immunosuppression. Clinicians should emphasize sun protection, routine follow-up, and patient education to minimize risk and improve outcomes. Further research is needed to clarify these associations.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Selenium Disulfide-Based Shampoo Is Beneficial for Dandruff Management and Rebalancing the Scalp Microbiome of Subjects of Any Hair Type. 含二硫化硒的洗发水对任何发质的头皮屑管理和头皮微生物群的平衡都有好处。

IF 1.4

Skin Appendage Disorders Pub Date : 2025-03-11 DOI: 10.1159/000544742

Pascal Edouard Reygagne, Claire Deloche-Bensmaine, Stephanie Leclerc-Mercier, Julie Faure, Natalia Kovylkina, Cecile Clavaud, Audrey Gueniche, Victoria Barbosa

{"title":"A Selenium Disulfide-Based Shampoo Is Beneficial for Dandruff Management and Rebalancing the Scalp Microbiome of Subjects of Any Hair Type.","authors":"Pascal Edouard Reygagne, Claire Deloche-Bensmaine, Stephanie Leclerc-Mercier, Julie Faure, Natalia Kovylkina, Cecile Clavaud, Audrey Gueniche, Victoria Barbosa","doi":"10.1159/000544742","DOIUrl":"10.1159/000544742","url":null,"abstract":"Introduction: Dandruff is a chronic scalp condition occurring in all hair types. Selenium disulfide (SeS2) shampoo is beneficial in dandruff and rebalances the scalp microbiome. However, data regarding subjects with curly hair are missing. This study assessed the clinical and scalp microbiome benefits of SeS2 shampoo in subjects of any hair type with moderate-to-severe dandruff.Methods: A 6-week study in adult subjects of any De La Mettrie hair type (I-VIII) assessed total dandruff, SD severity score (SSSD), erythema, hair greasiness, quality of life, discomfort, local tolerance, perceived benefit, acceptability, cosmeticity, and changes in the scalp microbiota. SeS2 shampoo was applied twice every week.Results: Overall, 93 subjects of any hair type (women: 83%, hair types: I-III: 41%, IV-V: 29%, VI-VIII: 30%) were recruited. 69% were of European and 31% of African origin. SSSD and total dandruff scores were the highest in hair type IV-V, erythema scores in hair type I-III, and the itching score in hair type VI-VIII, with no differences between hair types for any parameter. After 4 weeks, clinical signs and subject assessments had significantly (all p < 0.05) decreased in all phototypes. SeS2 shampoo significantly (p < 0.001) rebalanced the scalp microbiome. All subjects highly appreciated its benefit, acceptability, and cosmeticity. SeS2 shampoo was well tolerated.Conclusion: SeS2 shampoo is beneficial in moderate-to-severe dandruff and rebalances the scalp microbiota in all hair types. SeS2 shampoo was highly appreciated by the subjects for its benefit, acceptability, and cosmeticity, allowing a potential improvement of compliance, including in the long term.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-12"},"PeriodicalIF":1.4,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0