Skin Appendage Disorders最新文献_第8页

Sensitive Scalp and Trichodynia: Epidemiology, Etiopathogenesis, Diagnosis, and Management 敏感头皮和毛痛症:流行病学、病因、诊断和管理

Skin Appendage Disorders Pub Date : 2023-09-21 DOI: 10.1159/000533795

Emilly Neves Souza, Alessandra Anzai, Carolina Oliveira Costa Fechine, Neusa Yuriko Sakai Valente, Ricardo Romiti

引用次数: 0

Hair-to-Hair Trichoscopy: An Objective Method to Assess Effectiveness of Botulinum Toxin in a Clinical Trial for Androgenetic Alopecia 毛发毛发镜:一种客观的方法来评估肉毒毒素在雄激素性脱发临床试验中的有效性

Skin Appendage Disorders Pub Date : 2023-09-21 DOI: 10.1159/000533796

Daniel Fernandes Melo, André Luiz Vairo Donda, Rita Fernanda Cortez de Almeida, Daniela Alves Pereira Antelo, Paulo Muller-Ramos, Carla Jorge Machado, Sidney Frattini, Antonella Tosti, Carlos Baptista Barcaui

{"title":"Hair-to-Hair Trichoscopy: An Objective Method to Assess Effectiveness of Botulinum Toxin in a Clinical Trial for Androgenetic Alopecia","authors":"Daniel Fernandes Melo, André Luiz Vairo Donda, Rita Fernanda Cortez de Almeida, Daniela Alves Pereira Antelo, Paulo Muller-Ramos, Carla Jorge Machado, Sidney Frattini, Antonella Tosti, Carlos Baptista Barcaui","doi":"10.1159/000533796","DOIUrl":"https://doi.org/10.1159/000533796","url":null,"abstract":"Introduction: Androgenetic alopecia (AGA) is the most common alopecia affecting both genders leading to a potential decrease in quality of life and self-esteem. A current concern in trichology is how to accurately measure clinical response in both daily medical practice and academic research. Hair-to-hair (H2H)-matching technology™ has recently emerged as a technique to evaluate variations in follicular units, hair shaft number, and thickness. This study aimed to describe the methodology employed in a clinical trial using this technology to test the efficacy of botulinum toxin (BT) for male AGA. Methods: This pilot study is a triple-blind, randomized, split scalp, placebo-controlled clinical trial. Patients enrolled were submitted to injections half of the scalp with 50 IU of BT and the other half with 1 mL of normal saline as a control. The trial involved three visits (weeks 0, 12, and 24) and 8 global clinical photographs followed by H2H-matching trichoscopy were captured before the injections at each visit. Paired t test analysis was employed for matched pairs of the following parameters: total hair count, the total number of terminal hair strands, average shaft thickness, and the number of hairs lost or gained during each visit. Then, the software compared the differences between the two sides (BT vs. placebo) per scalp zone and a long time. Conclusion: The combination of manually corrected image processing, follicular map, and H2H-matching technology™ appears to be the most precise way to evaluate changes in hair count and thickness over time. The design is reproducible and can help other researchers and dermatologists in their clinical practice to obtain reliable results in similar scientific research.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136239862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Hydroxychloroquine in Hair Disorders 羟氯喹在头发疾病中的应用

Skin Appendage Disorders Pub Date : 2023-09-19 DOI: 10.1159/000533583

Advaitaa Ravipati, Michael Randolph, Waleed Al-Salhi, Antonella Tosti

引用次数: 1

Atypical Presentation of Spitz Nevus: A Case Report 斯皮兹痣的非典型表现:1例报告

Skin Appendage Disorders Pub Date : 2023-09-06 DOI: 10.1159/000533385

Isabel Araiza-Atanacio, Andrea Venegas-Andrade, Sonia Toussaint-Caire, Carolina Palacios López

引用次数: 1

Plica Neuropathica in 2 Hispanic Patients 2例西班牙裔患者的皱襞神经病

Skin Appendage Disorders Pub Date : 2023-09-06 DOI: 10.1159/000531938

Daniel Asz-Sigall, César Ramos-Cavazos, Paulina Mariel Gay-Muñoz, Jessica González-Gutiérrez, Alejandra Guerrero-Álvarez, Eduardo Corona-Rodarte

{"title":"Plica Neuropathica in 2 Hispanic Patients","authors":"Daniel Asz-Sigall, César Ramos-Cavazos, Paulina Mariel Gay-Muñoz, Jessica González-Gutiérrez, Alejandra Guerrero-Álvarez, Eduardo Corona-Rodarte","doi":"10.1159/000531938","DOIUrl":"https://doi.org/10.1159/000531938","url":null,"abstract":"Introduction: Plica neuropathica (PN) is a rare, acquired, and irreversible condition characterized by the formation of a compacted mass of tangled hair held together by a hard keratin cement. Case Presentation: In case 1, a 50-year-old woman with history of contact dermatitis of the scalp presented with hair tangling and difficulty combing. Physical examination revealed a matted mass of hair with a dirty appearance and non-scarring alopecia. Case 2 involved a 46-year-old woman who experienced spontaneous hair matting after using various products, resulting in a dreadlock-like appearance. Clinical examination showed a compact and matted mass of hair with irregular twists, dirt, and yellowish exudate. Conclusion: PN’s exact pathogenesis is not fully understood, but it is believed to involve physical and chemical insults to the hair shaft. Risk factors include self-neglect, hair felting or rubbing, certain substances, religious practices, chemotherapy, immunosuppressive drugs, infections, and contact dermatitis. Trichoscopy can provide valuable clues for an accurate diagnosis, such as fractured hairs, bent hair shafts, trichorrhexis nodosa, retained telogen hairs, and twisted hairs. Treatment involves cutting the matted hair, and early-stage manual separation may be beneficial.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"V 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Truth or Trend – Misinformation Spreading Fast on TikTok: A Cross-Sectional Analysis of Onychomycosis Content 真相还是趋势——在TikTok上快速传播的错误信息:对甲真菌病内容的横断面分析

Skin Appendage Disorders Pub Date : 2023-09-01 DOI: 10.1159/000533319

Kelita A. Waterton, Shari R. Lipner

{"title":"Truth or Trend – Misinformation Spreading Fast on TikTok: A Cross-Sectional Analysis of Onychomycosis Content","authors":"Kelita A. Waterton, Shari R. Lipner","doi":"10.1159/000533319","DOIUrl":"https://doi.org/10.1159/000533319","url":null,"abstract":"Background: Onychomycosis is the most frequently diagnosed nail condition in clinical practice. With the growing popularity of TikTok and online health information-seeking behavior, it is imperative to understand onychomycosis-related content on this platform. Objective: Our objective was to assess content and quality of the most popular onychomycosis-related content on TikTok. Methods: We queried TikTok for videos using the search terms “onychomycosis” and “nail fungus” for the top 100 videos by view count, with DISCERN scoring used to rate videos for quality. Results: Average DISCERN score was 1.77 and dermatologists posted videos with the highest mean score (2.56). Most of the videos were educational (72%) and/or related to treatment (69%). Home remedies were recommended more often (58%) than FDA-approved therapies (7%). Physician versus nonphysician posted videos had higher mean DISCERN score (2.28 vs. 1.44) (p &lt; 0.001), greater view number (1,209,953 vs. 343,993) (p &lt; 0.05), and more often discussed medical therapy (p &lt; 0.05). Conclusion: While social media is a valuable resource for providing medical information to an interminable audience, there are significant shortcomings. Therefore, we recommend that dermatologists advise patients against relying on social media for medical information and consider using social media to provide accessible evidence-based health education on onychomycosis.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135688177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kaposi Sarcoma of the Nail Unit: A Case Report and Review of the Literature 甲部卡波西肉瘤1例报告及文献复习

Skin Appendage Disorders Pub Date : 2023-08-23 DOI: 10.1159/000532114

Jonathan Krygier, Ursula Sass, Isabelle Meiers, Alice Marneffe, Marine de Vicq de Cumptich, Bertrand Richert

引用次数: 0

Dasatinib-Induced Transverse Melanonychia 达沙替尼诱导的横向黑色素瘤

Skin Appendage Disorders Pub Date : 2023-08-21 DOI: 10.1159/000531928

Mehul Tyagi, Vishal Gaurav, Japnoor Kaur

{"title":"Dasatinib-Induced Transverse Melanonychia","authors":"Mehul Tyagi, Vishal Gaurav, Japnoor Kaur","doi":"10.1159/000531928","DOIUrl":"https://doi.org/10.1159/000531928","url":null,"abstract":"Introduction: Transverse melanonychia, characterized by grey to black pigmented bands traversing the nail plate, can occur as a side-effect of certain medications. While no documented reports specifically associate dasatinib, a tyrosine kinase inhibitor used in the treatment of chronic myeloid leukaemia (CML) and acute lymphoblastic leukaemia, with nail changes, we present a case of transverse melanonychia possibly related to dasatinib therapy. Case Report: A 54-year-old male with CML, receiving dasatinib for 1.5 years, presented with transverse pigmented lines involving all fingernails and toenails. Clinical examination revealed discrete bands of transverse melanonychia in the nails. Onychoscopy of all finger- and toenails revealed multiple longitudinal grey lines within transverse grey bands of homogeneous chromonychia. Based on clinical presentation, onychoscopic features, and temporal association with dasatinib therapy, a provisional diagnosis of dasatinib-induced transverse melanonychia was made. Discussion: The exact mechanisms underlying melanonychia are not fully understood but may involve nail matrix or toxicity, stimulation of nail-matrix melanocytes, or drug deposition within the nail plate. This case highlights the possibility of dasatinib-induced transverse melanonychia and underscores the importance of monitoring and evaluating nail changes in patients undergoing dasatinib treatment.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135876585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Fluconazole-Induced Fixed Drug Eruption of the Digit with Nail Matrix Involvement: A Case Report and Review of the Literature 复发性氟康唑致累及甲基质的手指固定药疹1例报告及文献复习

Skin Appendage Disorders Pub Date : 2023-08-18 DOI: 10.1159/000532112

Loren E. Hernandez, Arvin Jadoo, Brian Morrison

引用次数: 0

Fibro-Osseus Pseudotumor of the Digit: A Case Report and Review of Literature 手指纤维-骨假瘤1例报告及文献复习

Skin Appendage Disorders Pub Date : 2023-08-18 DOI: 10.1159/000532113

Chander Grover, Pratibha Gupta, Chhavi Gupta, Kaniyappan Nambiyar, Shitij Goel

引用次数: 0