Skeletal RadiologyPub Date : 2025-07-01Epub Date: 2024-11-28DOI: 10.1007/s00256-024-04823-z
Isabela A N Cruz, Júlio B Guimarães, Marco A S Ratti, Thomas M Link, Marcelo A C Nico, Alípio G Ormond Filho
{"title":"Unusual bone abnormalities from therapeutic ultrasound diathermy: a radiological case report.","authors":"Isabela A N Cruz, Júlio B Guimarães, Marco A S Ratti, Thomas M Link, Marcelo A C Nico, Alípio G Ormond Filho","doi":"10.1007/s00256-024-04823-z","DOIUrl":"10.1007/s00256-024-04823-z","url":null,"abstract":"<p><p>This report describes bone marrow abnormalities arising as a consequence of therapeutic ultrasound diathermy, which are an uncommon diagnostic entity. Over the period from 2018 to 2023, 11 patients were identified that showed abnormalities of the bone marrow on MRI, as a direct result of ultrasound diathermy treatment. These abnormalities displayed consistent imaging features, characterized by areas of low T1W and high T2W signal intensity with well-demarcated geographic margins and central fatty areas, as can be seen in bone infarction. The imaging findings were localized in the superficial aspect of the bone, near the skin surface, corresponding to the site of ultrasound insonation. The clinical relevance of this report stems from the scarcity of documented cases and the unfamiliarity of this diagnostic entity among radiologists and orthopedic surgeons. The specificity of the imaging findings, their typical location, and the potential for resolution with cessation of the diathermy therapy reinforces the importance of this report. Recognition of this condition enables understanding potential adverse effects of ultrasound diathermy, increasing awareness regarding the importance of adhering to safe techniques and the use of this physical treatment modality in clinical practice. This information is also useful to athletic trainers, physical therapists, physical medicine and rehabilitation clinicians, and anyone who might perform ultrasound diathermy.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1517-1523"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-22DOI: 10.1007/s00256-024-04858-2
Tina Shiang, Ged G Wieschhoff, Jim S Wu, Jacob C Mandell
{"title":"Comparison of patient radiation exposure and procedure time between CT-fluoroscopy and spiral CT for lumbar epidural steroid injections.","authors":"Tina Shiang, Ged G Wieschhoff, Jim S Wu, Jacob C Mandell","doi":"10.1007/s00256-024-04858-2","DOIUrl":"10.1007/s00256-024-04858-2","url":null,"abstract":"<p><strong>Objective: </strong>To compare patient radiation exposure and procedure time for lumbar epidural steroid injections (ESIs) performed under CT-fluoroscopy (CTF) vs spiral CT-guidance.</p><p><strong>Materials and methods: </strong>A retrospective cohort study of 767 consecutive lumbar ESIs performed between 2015-2023 using CTF vs spiral CT-guidance was conducted. Patient characteristics (age, sex, weight), procedural characteristics (injection level, type of ESI, trainee participation), and outcomes (patient radiation exposure, procedure time, pain relief, complications) were compared. Student's t and chi-squared tests were performed for statistical analysis.</p><p><strong>Results: </strong>There were 240 CTF and 527 spiral CT-guided lumbar ESIs. There were no significant differences in patient demographics between groups. Radiation exposure for the CTF group was 37.2 ± 50.5 mGy <math><mo>∙</mo></math> cm, compared to 251.1 ± 178.6 mGy <math><mo>∙</mo></math> cm in the spiral CT group (p < 0.001). Procedure times were shorter in the CTF group (20.1 ± 6.1 vs 29.6 ± 12.9 min, p < 0.001). There was no significant difference in immediate post-procedure pain reduction in CTF vs spiral CT groups (p = 0.12). There were no intrathecal puncture complications in the CTF group and four in the spiral CT group. Subgroup analysis of attending-only and trainee-performed lumbar ESIs comparing CTF vs spiral-CT groups showed similar results as the primary analysis, with significant reductions in patient radiation (attending: 31.6 ± 40.7 vs 144.4 ± 97.4 mGy <math><mo>∙</mo></math> cm; trainee: 40.7 ± 55.5 vs 264.5 ± 182.0 mGy <math><mo>∙</mo></math> cm; both p < 0.001) and procedural time (attending: 18.3 ± 4.2 vs 24.4 ± 7.4 min; trainee: 21.2 ± 6.8 vs 30.2 ± 12.4; both p < 0.001).</p><p><strong>Conclusion: </strong>Image-guided lumbar ESIs using CTF were associated with less patient radiation exposure and shorter procedure times without differences in pain relief when compared with spiral CT technique in our practice.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1491-1501"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-09DOI: 10.1007/s00256-024-04843-9
Anna M P Boeren, Dennis A Ton, Elise van Mulligen, Bianca Boxma-de Klerk, Pascal H P de Jong, Edwin H G Oei, Monique Reijnierse, Annette H M van der Helm-van Mil
{"title":"A simplified fluid-sensitive MRI protocol for the hands to detect inflammation without contrast administration: a large study of symptom-free subjects from the general population as a reference for normality.","authors":"Anna M P Boeren, Dennis A Ton, Elise van Mulligen, Bianca Boxma-de Klerk, Pascal H P de Jong, Edwin H G Oei, Monique Reijnierse, Annette H M van der Helm-van Mil","doi":"10.1007/s00256-024-04843-9","DOIUrl":"10.1007/s00256-024-04843-9","url":null,"abstract":"<p><strong>Objective: </strong>MRI of the hands is valuable for risk-stratification in patients with arthralgia at-risk for developing rheumatoid arthritis (RA). Contrast-enhanced MRI is considered standard for assessment of RA, but has practical disadvantages. It also shows inflammation-like features in the general population, especially at older age, which should be considered in image interpretation. The modified-Dixon (mDixon) technique is reliable compared to contrast-enhanced sequences. Moreover, this short protocol without contrast-enhancement is patient-friendly. Whether it also shows inflammation-like features in the general population is unknown. We studied this to support accurate use in the clinic.</p><p><strong>Methods: </strong>Two hundred twenty symptom-free volunteers from different age-categories were recruited from the general population and underwent mDixon MRI of both hands. Two readers independently scored MRIs for synovitis, tenosynovitis, and bone marrow edema (BME) in the metacarpophalangeal-joints (MCP) and wrists according to the RAMRIS. Features were considered present if scored by both readers; frequencies > 5% were considered relevant in terms of specificity and determined per age-category (< 40/40- < 60/ ≥ 60-years).</p><p><strong>Results: </strong>Higher age correlated with higher BME-scores (p-value < 0.005), but not with synovitis and tenosynovitis-scores. BME (grade 1) occurred in some bones in people aged ≥ 60, 14% had BME in the lunate, 7% in metacarpal-1, and 6% in the trapezium. Synovitis and tenosynovitis did not occur in > 5%, except for grade-1 synovitis in the right distal radio-ulnar-joint in people aged ≥ 60 (11%).</p><p><strong>Conclusion: </strong>On mDixon MRI, inflammatory features in the hands of the general population are rare. This facilitates image interpretation. To prevent overinterpretation, only several locations should be considered when evaluating people aged ≥ 60-years.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1429-1439"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-11DOI: 10.1007/s00256-024-04845-7
Sophia S Goller, Georg W Kajdi, Stephan Wirth, Jess G Snedeker, Reto Sutter
{"title":"Assessment of calf muscle constitution in chronic Achilles tendon disease using Dixon-based MRI.","authors":"Sophia S Goller, Georg W Kajdi, Stephan Wirth, Jess G Snedeker, Reto Sutter","doi":"10.1007/s00256-024-04845-7","DOIUrl":"10.1007/s00256-024-04845-7","url":null,"abstract":"<p><strong>Objectives: </strong>To assess calf muscle constitution in chronic Achilles tendon disease (ATD) using two-point Dixon-based MRI (2pt-MRI<sub>DIXON</sub>).</p><p><strong>Materials and methods: </strong>This retrospective study analyzed 91 patients (36 females; 57.0 ± 14.4 years) with midportion or insertional chronic ATD who underwent clinical MRI of the Achilles tendon (AT), including 2pt-MRI<sub>DIXON</sub> for quantitative assessment of calf muscle fat content (MFC). Additionally, two radiologists qualitatively assessed MFC, AT quality, and co-pathologies. 2pt-MRI<sub>DIXON</sub>-derived fat fractions (FF) were related to patients' demographics and qualitative imaging findings.</p><p><strong>Results: </strong>The overall mean FF derived from 2pt-MRI<sub>DIXON</sub> of the triceps surae muscle was 11.2 ± 9.3%. Comparing midportion and insertional ATD, there was no significant difference regarding fatty muscle infiltration assessed with 2pt-MRI<sub>DIXON</sub> (P ≥ .47) or qualitative grading (P ≥ .059). More severe AT thickening (11 vs.9 mm, P < .001) and complete tears (29 vs. 9%, P = .025) were significantly more common in midportion ATD, while partial tears were significantly more frequent in insertional ATD (55 vs. 31%, P = .027). Soleus muscle edema was more prevalent in midportion than insertional ATD (40 vs. 9%, P = .002). In contrast, insertional ATD more commonly featured bone marrow edema (61 vs. 2%), Haglund's deformity (67 vs. 0%), and retrocalcaneal bursitis (82 vs. 43%) (P ≤ .002). Significant correlations (P ≤ .001) were demonstrated between FF, AT diameter, age (both in midportion and insertional ATD), and body mass index (in midportion ATD only) (ρ range = 0.53-0.61).</p><p><strong>Conclusion: </strong>In chronic ATD, calf MFC was statistically equivalent (approximately 11%), irrespective of the localization of tendon damage. More severe tendon thickening and complete tears were more common in midportion ATD, and, vice versa, partial AT tears were significantly more frequent in insertional ATD.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1457-1468"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-04DOI: 10.1007/s00256-024-04837-7
Nana Zhu, Feige Niu, Shuxuan Fan, Xianghong Meng, Yongcheng Hu, Jun Han, Zhi Wang
{"title":"Predicting progression-free survival in sarcoma using MRI-based automatic segmentation models and radiomics nomograms: a preliminary multicenter study.","authors":"Nana Zhu, Feige Niu, Shuxuan Fan, Xianghong Meng, Yongcheng Hu, Jun Han, Zhi Wang","doi":"10.1007/s00256-024-04837-7","DOIUrl":"10.1007/s00256-024-04837-7","url":null,"abstract":"<p><strong>Objectives: </strong>Some sarcomas are highly malignant, associated with high recurrence despite treatment. This multicenter study aimed to develop and validate a radiomics signature to estimate sarcoma progression-free survival (PFS).</p><p><strong>Materials and methods: </strong>The study retrospectively enrolled 202 consecutive patients with pathologically diagnosed sarcoma, who had pre-treatment axial fat-suppressed T2-weighted images (FS-T2WI), and included them in the ROI-Net model for training. Among them, 120 patients were included in the radiomics analysis, all of whom had pre-treatment axial T1-weighted and transverse FS-T2WI images, and were randomly divided into a development group (n = 96) and a validation group (n = 24). In the development cohort, Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression was used to develop the radiomics features for PFS prediction. By combining significant clinical features with radiomics features, a nomogram was constructed using Cox regression.</p><p><strong>Results: </strong>The proposed ROI-Net framework achieved a Dice coefficient of 0.820 (0.791-0.848). The radiomics signature based on 21 features could distinguish high-risk patients with poor PFS. Univariate Cox analysis revealed that peritumoral edema, metastases, and the radiomics score were associated with poor PFS and were included in the construction of the nomogram. The Radiomics-T1WI-Clinical model exhibited the best performance, with AUC values of 0.947, 0.907, and 0.924 at 300 days, 600 days, and 900 days, respectively.</p><p><strong>Conclusion: </strong>The proposed ROI-Net framework demonstrated high consistency between its segmentation results and expert annotations. The radiomics features and the combined nomogram have the potential to aid in predicting PFS for patients with sarcoma.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1417-1427"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahyar Daskareh, Melissa Lou Silva, Hamidreza Shaterian Mohammadi, Arya Suprana, Dina Moazamian, Saeed Jerban, Yajun Ma
{"title":"Assessment of vastus medialis muscle quality in knee osteoarthritis using ultrashort echo time magnetization transfer MR imaging.","authors":"Mahyar Daskareh, Melissa Lou Silva, Hamidreza Shaterian Mohammadi, Arya Suprana, Dina Moazamian, Saeed Jerban, Yajun Ma","doi":"10.1007/s00256-025-04977-4","DOIUrl":"https://doi.org/10.1007/s00256-025-04977-4","url":null,"abstract":"<p><strong>Objectives: </strong>Knee osteoarthritis (KOA) is a leading cause of disability, driven by cartilage degeneration, joint inflammation, and biomechanical stress. Beyond these changes, quadriceps muscle (QM) degradation, particularly in the vastus medialis (VM), has emerged as a key contributor to symptomatic KOA. Clinical MRI primarily offers qualitative assessments of muscle alterations, with limited ability to evaluate compositional changes, especially in collagen content. Novel ultrashort echo time magnetization transfer (UTE-MT) is a quantitative technique that can be used to evaluate muscle in KOA.</p><p><strong>Materials and methods: </strong>This cross-sectional study included 54 participants (mean age: 53 ± 17 years), comprising healthy volunteers and patients with knee osteoarthritis (KOA). Knee MRI was performed to map the magnetization transfer ratio (MTR) of the VM. Intramuscular fat infiltration was classified using the Goutallier score (GS). The performance of UTE-MTR was compared with that of the GS assessed on T1-weighted imaging (T1WI) and with UTE-T1 and UTE-T2* measurements. Correlation analysis was applied to assess the relationship between VM MRI biomarkers and KOA severity, classified according to the Kellgren-Lawrence (KL) grading. An ordinal regression model was designed to estimate the severity of KOA based on UTE-derived measurements.</p><p><strong>Results: </strong>UTE-MTR of the VM demonstrated a strong negative correlation with KL groups (r = - 0.82), outperforming T1WI (r = 0.55) for GS classification, as well as UTE-T1 (r = - 0.60) and UTE-T2* (r = - 0.50) techniques. The ordinal regression model identified UTE-MTR as the only statistically significant indicator of OA severity (adjusted odds ratio: 0.13).</p><p><strong>Conclusions: </strong>UTE-MTR is a promising quantitative imaging biomarker for assessing VM muscle degradation in KOA.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144542160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark J Kransdorf, Brandon T Larsen, Mark D Murphey, Jeremiah R Long
{"title":"Imaging features of nodular fasciitis: a review of 89 cases.","authors":"Mark J Kransdorf, Brandon T Larsen, Mark D Murphey, Jeremiah R Long","doi":"10.1007/s00256-025-04973-8","DOIUrl":"https://doi.org/10.1007/s00256-025-04973-8","url":null,"abstract":"<p><strong>Objective: </strong>To review the spectrum of clinical and imaging features of nodular fasciitis, emphasizing those most characteristic of this diagnosis.</p><p><strong>Material and methods: </strong>A retrospective review of our institutional pathology and imaging databases from 2006 to 2024 identified 89 patients with confirmed nodular fasciitis pathology and imaging evaluation. For the purpose of analysis, lesions were subdivided into 2 basic groups: superficial and deep. Superficial lesions were defined as those involving the skin, superficial fascia, subcutaneous fat, and/or extending to the deep fascia. Deep lesions were defined as those localized to the deep fascia or extending deep to the deep fascia, as well as those that were intermuscular or intramuscular.</p><p><strong>Results: </strong> There were 45 females and 44 males with an overall average age of 37.3 years (range 1.5-84 years; 68.5% between 20 and 60 years). There were 30 superficial lesions (33.7%) and 59 (66.3%) deep lesions. Deep lesions were on average 65% larger than those located superficially and patients with deep lesions were on average 7.2 years older than those with superficial lesions. While there are no pathognomonic imaging features, careful attention to the relationship of the lesion to the adjacent fascia, as well as to the identification of characteristic time-dependent lesional MR signal changes can be useful aids in identifying this lesion.</p><p><strong>Conclusion: </strong>While nodular fasciitis is often considered to be an uncommon soft tissue tumor, it is recognized as the third most common benign soft tissue lesion. Knowledge of the spectrum of lesion characteristic locations and appearances will facilitate definitive diagnosis.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitor Neves Sato, Tatiane Lumi Moriwaki, Leonardo Kazunori Tsuji, Daisy Terumi Kase, Lucas Kenzo Miyahara, Andre Hiroki Suyama Tsuji, Adham do Amaral E Castro, Carolina Freitas Lins, André Fukunishi Yamada, Artur da Rocha Correa Fernandes, Marcello Henrique Nogueira-Barbosa, Júlio Brandão Guimarães, André Yui Aihara
{"title":"Musculoskeletal manifestations of sickle cell disease: an imaging perspective.","authors":"Vitor Neves Sato, Tatiane Lumi Moriwaki, Leonardo Kazunori Tsuji, Daisy Terumi Kase, Lucas Kenzo Miyahara, Andre Hiroki Suyama Tsuji, Adham do Amaral E Castro, Carolina Freitas Lins, André Fukunishi Yamada, Artur da Rocha Correa Fernandes, Marcello Henrique Nogueira-Barbosa, Júlio Brandão Guimarães, André Yui Aihara","doi":"10.1007/s00256-025-04975-6","DOIUrl":"10.1007/s00256-025-04975-6","url":null,"abstract":"<p><p>Sickle cell disease (SCD) is a spectrum of inherited blood disorders, leading to propensity to sickling disruption of red blood cells. Musculoskeletal complications are a common cause of acute and chronic morbidities, related to the main pathophysiological processes: (i) hemolysis and anemia, resulting in marrow hyperplasia and extramedullary hematopoiesis; and (ii) vaso-occlusion, leading to osteonecrosis/bone infarction, myonecrosis, and infection (osteomyelitis and septic arthritis). Knowing the pathophysiology and clinical manifestations is essential for imaging interpretation, but differentiation between acute osteomyelitis and bone infarction remains a clinical and imaging challenge, therefore requiring a multidisciplinary approach. Large subperiosteal fluid collections (≥ 4 mm in depth), in conjunction with elevated inflammatory markers and white blood counts, are more suggestive of osteomyelitis rather than isolated bone infarction. The unenhanced T1-weighted fat-suppressed sequence on MR images was also proposed to aid in this differentiation, but so far with controversial results. Future perspectives of MR imaging include the DIXON technique, which has shown promising results as a biomarker of morbidity of SCD, through evaluation of fat fraction (FF) of bone marrow in a single acquisition and noninvasive way.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent developments in pharmacologic therapy of synovitis in osteoarthritis.","authors":"Francis Berenbaum","doi":"10.1007/s00256-025-04976-5","DOIUrl":"10.1007/s00256-025-04976-5","url":null,"abstract":"<p><p>Osteoarthritis (OA) is now considered an inflammatory disease in which synovitis has an active role in the generation of pain and structural progression. Despite attempts to reposition treatments for rheumatoid arthritis without conclusive success, synovitis remains a viable therapeutic target to slow progression and enhance the quality of life of OA patients. This review highlights the main targets explored today at the clinical and preclinical levels with the goal to not only relieve the symptoms but also to provide real disease modifying treatments that can prevent further joint damage and improve joint function by treating synovitis.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oscar Luis Casado-Verdugo, Victoria Isabel Carnerero Herrera, Iban Aransaez Aguirre, Idoia Gutierrez Sanchez, Jofre Tenorio-Laranga, Estrella Prieto Sanchez
{"title":"MRI of early potential complications of subacromial balloon implantation: a retrospective cross-sectional study.","authors":"Oscar Luis Casado-Verdugo, Victoria Isabel Carnerero Herrera, Iban Aransaez Aguirre, Idoia Gutierrez Sanchez, Jofre Tenorio-Laranga, Estrella Prieto Sanchez","doi":"10.1007/s00256-025-04974-7","DOIUrl":"10.1007/s00256-025-04974-7","url":null,"abstract":"<p><strong>Objective: </strong>To describe MRI application in the follow-up of subacromial balloon implantation and to show MRI findings of early displacement, balloon morphologies, and their potential association with synovitis and chondrolysis within the first-year post-implantation.</p><p><strong>Materials and methods: </strong>Data were retrospectively collected from 18 consecutive shoulder MRI studies performed in symptomatic cases after balloon implantation. MRI studies were done randomly once during the first year after balloon implantation in a single tertiary-care institution. MRI studies performed after 1 year of implantation were excluded (n = 3). Normal subacromial versus displaced balloon location, morphology of the subacromial or displaced balloon, type of synovitis, and evolution of synovitis and chondropathy compared to presurgical MRI studies were recorded. Arthroscopic surgery for balloon replacement was not performed as reference standard. Descriptive statistics were utilized to display the findings: chi-square and Fisher's exact tests to assess associations between implant morphology and evolution of synovitis or chondropathy; Kruskal-Wallis and post hoc tests to assess associations between implant morphology and time since surgery.</p><p><strong>Results: </strong>The balloon was posteriorly displaced in the glenohumeral joint or in the subdeltoid bursa in most cases (72.22%). The displaced balloon showed folded, band-like or pseudomass morphologies, and the morphology type was statistically associated with point time from surgery (p = 0.021). Papillary synovitis largely prevailed (77.7%). No statistical association was found between implant morphology and evolution of synovitis or chondropathy (p > 0.05).</p><p><strong>Conclusion: </strong>In symptomatic patients following subacromial ballon implantation, MRI is useful in diagnosing complications including displacement, collapse and reactive synovitis.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}