Skeletal Radiology最新文献_第9页

A case report of pediatric Gardner syndrome and literature review. 小儿加德纳综合征1例报告并文献复习。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-13 DOI: 10.1007/s00256-026-05390-1

Meitao Liu, Siping He

{"title":"A case report of pediatric Gardner syndrome and literature review.","authors":"Meitao Liu, Siping He","doi":"10.1007/s00256-026-05390-1","DOIUrl":"https://doi.org/10.1007/s00256-026-05390-1","url":null,"abstract":"This case report discusses the diagnosis and treatment of a 14-year-8-month-old male patient genetically diagnosed with Gardner syndrome (GS), systematically reviewing the disease's epidemiology, clinical manifestations, imaging advances, and management strategies. The patient presented with a post-influenza A chest wall mass and had prior resections of abdominal/scalp masses. Colonoscopy revealed > 20 adenomatous polyps. Imaging demonstrated multiple craniofacial osteomas and epidermoid cysts. Genetic testing identified a pathogenic APC gene mutation (NM_000038.6:c.4669_4670del (p.Ile1557*) heterozygous variant). GS, a familial adenomatous polyposis (FAP) subtype, has an estimated pediatric incidence of 1/8000-1/14,000. Its classic triad comprises colorectal polyps, osteomas, and soft tissue tumors. Recent studies indicate earlier malignant transformation of duodenal polyps in children versus adults, with desmoid tumor incidence reaching 10-20%. In imaging, low-dose CT, panoramic radiography, and contrast-enhanced MRI can improve early detection of bone lesions and soft tissue tumors. Genetic testing (APC/MUTYH) is the pediatric screening gold standard. Optimized chemoprevention (sulindac/celecoxib) and endoscopic monitoring have significantly improved prognoses. This case highlights the urgency of multidisciplinary management and genetic counseling for pediatric GS.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute glenoid rim fractures: reliability of linear and surface area methods for CT-based bone loss assessment. 急性盂缘骨折：基于ct的骨损失评估的线性和表面积方法的可靠性。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-13 DOI: 10.1007/s00256-026-05389-8

Katarina Lindgren, Lars Adolfsson, Anders Stålman, Erica Domeij-Arverud, Karin Kockum

{"title":"Acute glenoid rim fractures: reliability of linear and surface area methods for CT-based bone loss assessment.","authors":"Katarina Lindgren, Lars Adolfsson, Anders Stålman, Erica Domeij-Arverud, Karin Kockum","doi":"10.1007/s00256-026-05389-8","DOIUrl":"https://doi.org/10.1007/s00256-026-05389-8","url":null,"abstract":"Objective: We wanted to investigate and compare the reliability of two measuring methods for glenoid bone loss, one linear- and one surface area method, in acute glenoid fractures after dislocation. This was an experimental study.Method: Thirty CT-shoulder scans in patients with an acute glenoid rim fracture were measured in a lateral\"en face\" view in 2D and 3D by two independent assessors. In 10 of 30 patients contralateral shoulder CT-scan was obtained for reference circle placement. Intra- and interrater reliability was analysed by Intra Class Correlation. Wilcoxon signed rank test was performed for comparison of bone loss estimates between methods.Results: The reliability ranged from 0.85 to 0.97 for the two methods in both 2D and 3D, which is considered good to excellent. The bone loss estimates were significantly larger with linear method than area method. Drawing of a best-fitting-circle had a good reliability between assessors.Conclusions: Linear- and surface area methods demonstrated comparable reliability in assessing glenoid bone loss in acute fractures and we found no difference between 2D- and 3D-modalities. However, linear methods may overestimate defect in cases with irregular fracture lines, suggesting area method may be preferable in acute fractures.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When AI says DOUBT: why abstention should be part of diagnostic performance. 当人工智能说怀疑：为什么弃权应该是诊断表现的一部分。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-13 DOI: 10.1007/s00256-026-05397-8

Alexander Reyes Lobo

引用次数: 0

Ultrasound-guided injection treatments for tendinopathy: an update. 超声引导下肌腱病变注射治疗：最新进展。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-12 DOI: 10.1007/s00256-026-05396-9

Lionel Pesquer, Philippe Meyer, Alessandra Ross, Benjamin Dallaudiere, Alain Silvestre

引用次数: 0

Primary leiomyosarcoma arising adjacent to a femoral stem following total hip arthroplasty: a case report with radiologic and histopathological correlation. 全髋关节置换术后发生于股干附近的原发性平滑肌肉瘤：1例与放射学和组织病理学相关的报告。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-12 DOI: 10.1007/s00256-026-05391-0

Sakura Shiraishi, Toshifumi Fujiwara, Satoshi Hamai, Taro Mori, Nobuhiko Yokoyama, Akira Nabeshima, Makoto Endo, Yasuharu Nakashima, Yoshinao Oda

{"title":"Primary leiomyosarcoma arising adjacent to a femoral stem following total hip arthroplasty: a case report with radiologic and histopathological correlation.","authors":"Sakura Shiraishi, Toshifumi Fujiwara, Satoshi Hamai, Taro Mori, Nobuhiko Yokoyama, Akira Nabeshima, Makoto Endo, Yasuharu Nakashima, Yoshinao Oda","doi":"10.1007/s00256-026-05391-0","DOIUrl":"https://doi.org/10.1007/s00256-026-05391-0","url":null,"abstract":"Periprosthetic sarcomas associated with total hip arthroplasty (THA) are exceedingly rare, and most reported cases represent undifferentiated pleomorphic sarcoma or osteosarcoma. Primary leiomyosarcoma of bone is also an uncommon malignancy, accounting for less than 1% of primary malignant bone tumors. The occurrence of primary leiomyosarcoma adjacent to an orthopedic implant is therefore exceptionally rare. A 69-year-old woman presented with progressive left thigh pain 13 years after THA. Radiographs demonstrated osteolysis and cortical thinning at the distal femoral stem. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed an intramedullary lesion with cortical thinning and contrast enhancement. 18F-fluorodeoxyglucose positron emission tomography-CT showed increased uptake at the lesion (SUV max, 11.9), without evidence of other primary tumors. The differential diagnoses included implant-related osteolysis, infection, metastatic tumor, and primary bone tumor. An open biopsy was performed, and a diagnosis of pleomorphic sarcoma was made. Wide resection with proximal femoral replacement was performed. Histopathological examination established the diagnosis of primary leiomyosarcoma of bone. Prominent lymphocytic infiltration and immunohistochemical findings, including p53 overexpression and partial loss of Rb expression, within the tumor, raise the possibility of chronic inflammation and associated molecular alterations as theoretical contributing factors to tumorigenesis. Periprosthetic sarcomas can mimic more common postoperative complications, making diagnosis challenging. Delayed diagnosis may adversely affect prognosis. This case highlights the importance of considering malignancy in atypical periprosthetic lesions and underscores the role of multimodality imaging and biopsy in achieving an accurate diagnosis.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CIC-rearranged sarcoma of the arm presenting as a soft tissue mass with regional lymphadenopathy and tumor thrombus. 手臂cic重排肉瘤，表现为软组织肿块，伴有局部淋巴结病变和肿瘤血栓。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-09 DOI: 10.1007/s00256-026-05384-z

Manish Saini, Stuti Chandola, Sameer Rastogi, Adarsh Barwad, Shamim Ahmed Shamim, Stanzin Spalkit

引用次数: 0

Atypical spindle cell/pleomorphic lipomatous tumor with sarcomatous transformation during recurrence. 不典型梭形细胞/多形性脂肪瘤复发时伴肉瘤转化。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-07 DOI: 10.1007/s00256-026-05385-y

Jens De Temmerman, Thomas Van Den Berghe, Fleur Cordier, Desirée Dorleijn, Kiara Peirens, Maryse Lejoly, Ruben Rimbaut, Gwen Sys, David Creytens, Koenraad L Verstraete

{"title":"Atypical spindle cell/pleomorphic lipomatous tumor with sarcomatous transformation during recurrence.","authors":"Jens De Temmerman, Thomas Van Den Berghe, Fleur Cordier, Desirée Dorleijn, Kiara Peirens, Maryse Lejoly, Ruben Rimbaut, Gwen Sys, David Creytens, Koenraad L Verstraete","doi":"10.1007/s00256-026-05385-y","DOIUrl":"https://doi.org/10.1007/s00256-026-05385-y","url":null,"abstract":"Atypical spindle cell/pleomorphic lipomatous tumor (ASPLT) is a recently defined adipocytic neoplasm with broad morphological variability. While generally benign, a small subset of ASPLT can demonstrate locally aggressive behavior with recurrences after incomplete resection. There is only limited description of the radiologic features of ASPLT in the literature. This case report presents a unique longitudinal case of a 75-year-old woman with an ASPLT in the subcutaneous tissue of the left lower leg. Following two incomplete resections, the tumor recurred twice over 38 months, each time with increasing volume and growth rate. The second recurrence demonstrated abrupt histological transition from low-grade ASPLT to high-grade undifferentiated sarcoma, with underlying RB1 deletion, an additional NF1 gene mutation, and a complex genomic profile. The tumors demonstrated low to intermediate signal intensity on T1-weighted imaging and heterogeneous enhancement on T1-weighted fat-saturated images after contrast agent injection. Dynamic contrast-enhanced (DCE)-MRI revealed heterogeneous perfusion patterns correlating to sarcomatous regions. Elevated (semi-)quantitative DCE-MRI parameters, reflecting increased vascularization, perfusion, and high capillary permeability, were observed in histologically high-grade areas compared with low-grade regions. To the best of our knowledge, this is the first in-depth clinicoradiological study documenting transformation of an ASPLT into a high-grade undifferentiated sarcoma following incomplete surgery. This case also emphasizes the diagnostic value of DCE-MRI in identifying biologically aggressive (high-grade) regions within ASPLTs undergoing sarcomatous transformation.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep learning-based synthetic CT for the assessment of spinal structural lesions in axial spondyloarthritis. 基于深度学习的合成CT对中轴性脊柱炎脊柱结构病变的评估。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-07 DOI: 10.1007/s00256-026-05371-4

Qinxin Cai, Kelly Di Dier, Lieve Morbée, Nele Herregods, Elke Vereecke, Min Chen, Thomas Van Den Berghe, Wei Li, Eva Schiettecatte, Jacob L Jaremko, Lennart Jans

{"title":"Deep learning-based synthetic CT for the assessment of spinal structural lesions in axial spondyloarthritis.","authors":"Qinxin Cai, Kelly Di Dier, Lieve Morbée, Nele Herregods, Elke Vereecke, Min Chen, Thomas Van Den Berghe, Wei Li, Eva Schiettecatte, Jacob L Jaremko, Lennart Jans","doi":"10.1007/s00256-026-05371-4","DOIUrl":"https://doi.org/10.1007/s00256-026-05371-4","url":null,"abstract":"Objective: To evaluate the accuracy of synthetic CT for detecting spinal structural lesions in patients with suspected axial spondyloarthritis (axSpA).Materials and methods: Patients with inflammatory back pain who underwent both spinal CT and MRI examinations were included in this retrospective study. Two readers independently assessed the presence of structural lesions (facet joint ankylosis, structural Andersson lesions, discal ossifications, vertebral ankylosis, syndesmophytes, and erosions) on conventional CT and synthetic CT images. Feature detection accuracy of synthetic CT relative to conventional CT was evaluated using sensitivity, specificity, positive predictive value, and negative predictive value, with consensus reading as the reference standard. In addition, lesion-level erosion detection accuracy was assessed, and erosion size was compared between conventional CT and synthetic CT.Results: Eighty-seven patients (mean age, 41 ± 14.2 years; range, 18-80 years; 42 males and 45 females) were included. Sensitivity of synthetic CT was 1.00 for facet joint ankylosis, structural Andersson lesions, vertebral ankylosis, and erosions, 0.91 for syndesmophytes, and 0.67 for discal ossifications. Specificity ranged from 0.97 to 1.00 across all lesion types. Lesion-level analysis showed sensitivity of 0.82-1.00 and specificity of 0.96-1.00 for erosion detection across different spinal regions. No significant differences of erosion size (median [IQR], mm) between conventional CT and synthetic CT (width, 7.7 [4.4-9.7] vs. 8.0 [4.1-9.6], P = 0.15; depth, 4.5 [3.5-6.7] vs. 4.5 [3.5-6.5], P = 0.12).Conclusion: Synthetic CT demonstrates a high feature detection accuracy for assessing most spinal structural lesions in patients with suspected axSpA.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging of acute sports injuries of the shoulder girdle. 肩带急性运动损伤的影像学分析。

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-07 DOI: 10.1007/s00256-026-05375-0

Nehal Shah, William E Palmer, Vy Pham Thao Vu, Jim S Wu, Kirstin M Small

引用次数: 0

Are ipsilateral proximal femur and pubic rami fractures mutually exclusive in acute trauma? 同侧股骨近端骨折和耻骨骨折在急性创伤中是否相互排斥？

IF 2.5 3区医学

Skeletal Radiology Pub Date : 2026-10-06 DOI: 10.1007/s00256-026-05383-0

Kawan S Rakhra, Olaitan Ogunkinle, Jin Hui Yan, Ryan Foster

{"title":"Are ipsilateral proximal femur and pubic rami fractures mutually exclusive in acute trauma?","authors":"Kawan S Rakhra, Olaitan Ogunkinle, Jin Hui Yan, Ryan Foster","doi":"10.1007/s00256-026-05383-0","DOIUrl":"https://doi.org/10.1007/s00256-026-05383-0","url":null,"abstract":"Objective: To determine whether proximal femur and pubic rami fractures are mutually exclusive in acute trauma.Methods: Pelvic/hip radiographs of consecutive adult patients presenting to ER with acute trauma at a tertiary, university hospital between January 1 and December 31, 2020, were retrospectively reviewed for proximal femur and/or pubic ramus fractures. The number of fractures, fracture location, age and gender were recorded. Cases with concomitant pubic rami and proximal femoral fractures were identified. Electronic records confirmed the history of trauma and mechanism of injury (low energy or high energy). Continuous data variables were summarized using descriptive statistics of mean, range and standard deviation. Categorical variables were summarized as count and percentages with proportions compared using Chi-square test.Results: A total of 1967 patients were included (826 male, 1141 female; mean age 69 years [range 18-119, SD 22]). There were 633 fractures in 624 patients, 125 pubic ramus (19.7% of total, 68.8% females) and 508 proximal femur (80.3% of total, 67.9% females). Injury mechanism was predominantly low energy for both pubic ramus (53%) and proximal femur (91%) fractures. The incidence of concomitant pubic ramus and proximal femur fractures was 1.4% (9/624). Of these 9 cases, two subgroups emerged: (1) 3 middle-aged patients of age 44-62 years, with high energy mechanism, all with subtrochanteric proximal femur fracture, and (2) 6 elderly patients, all age > 90 years, with low energy mechanism, with femoral neck or intertrochanteric proximal femur fracture.Conclusion: Proximal femur and pubic ramus fractures are not mutually exclusive, although their coexistence is rare.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0