Skin Research and Technology最新文献

{"title":"Expression of Concern: M6A- and m5C- Modified LncRNAs Orchestrate the Prognosis in Cutaneous Melanoma and m6A- Modified LINC00893 Regulates Cutaneous Melanoma Cell Metastasis.","authors":"","doi":"10.1111/srt.70175","DOIUrl":"https://doi.org/10.1111/srt.70175","url":null,"abstract":"","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70175"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Interventions for Apocrine, Eccrine, and Pseudo Chromhidrosis: An Overview of the Current Literature.","authors":"Jimmy Dhillon, Madeline Tchack, Bassem Rafiq, Noah Musolff, Babar Rao","doi":"10.1111/srt.70167","DOIUrl":"https://doi.org/10.1111/srt.70167","url":null,"abstract":"","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70167"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: LncRNA SLNCR1 Facilitates Angiogenesis and Tumor Growth in Melanoma via DNMT1-Mediated Epigenetically Silencing SPRY2.","authors":"","doi":"10.1111/srt.70184","DOIUrl":"10.1111/srt.70184","url":null,"abstract":"","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70184"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Invasive Imaging for the Evaluation of a New Oral Supplement in Skin Aging: A Case-Controlled Study.","authors":"Simone Michelini, Maria Elisabetta Greco, Giordano Vespasiani, Federica Trovato, Camilla Chello, Noah Musolff, Carmen Cantisani, Giovanni Pellacani","doi":"10.1111/srt.70171","DOIUrl":"10.1111/srt.70171","url":null,"abstract":"<p><strong>Background: </strong>Skin aging represents a para-physiological process related to metabolic imbalances, inflammation, proliferative responses, and oxidative stress. Ending the cycle of inflammation, and oxidative stress represents a way to slow the effects of aging.</p><p><strong>Study objective: </strong>The aim of our study was to evaluate the benefits of supplements with an herbal mixture based on Venerinase and B-group vitamins, Zinc, and Magnesium in preventing/reducing photoaging by means of objective quantitative analysis of visual skin features obtained by VISIA 2D and stroma and vascular characteristics measured by Optical Coherence Tomography (OCT).</p><p><strong>Methods: </strong>A prospective clinical study was conducted in 40 participants. They were randomized 1:1 to receive the supplement (Giovina) or placebo. Assessments were conducted at Baseline (T0), after 2 months (T1), and after 4 months (T2). The primary endpoint was to obtain a significant improvement in facial photo/chrono-aging in the treatment arm, as assessed through the evaluation of the Griffith scale. Secondary endpoints were to assess significant changes in skin aging objective features (VISIA) and Optical Coherence Tomography (OCT) parameters.</p><p><strong>Results: </strong>The treated group showed a significant reduction in the mean Griffith scale score from 4.5 at baseline to 3.76 at T2 (4 months) (p = 0.001). A significant decrease in red areas and a borderline significant reduction in the number of wrinkles have been shown by skin aging objective feature calculation on VISIA 2D photographs. OCT analysis showed a borderline significant reduction in collagen density.</p><p><strong>Conclusions: </strong>The decrease in vascular pattern and collagen density suggests an anti-inflammatory effect with a potential stromal remodeling in the treated group. This seems to be correlated to the reduction in wrinkles and facial redness.</p>","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70171"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of the Relationship Between Hyaluronic Acid and Wound Healing: A Bibliometric Analysis.","authors":"Zhang Yue, Keke Shao","doi":"10.1111/srt.70164","DOIUrl":"https://doi.org/10.1111/srt.70164","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Wound healing is a complex process with significant economic implications. Hyaluronic acid (HA), valued for its adaptability and biocompatibility, shows the potential to improve multiple facets of wound healing. Despite the expanding literature on the use of HA in wound care, a comprehensive analysis of its scholarly evolution is lacking. This study employs a bibliometric approach to objectively evaluate trends in scholarly publications regarding HA's role in promoting wound healing.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We searched in the Web of Science Core Collection (WoSCC) for articles published from January 1, 2000 to March 31, 2024. We extracted relevant information about using HA to promote wound healing following a thorough screening process. Subsequently, a comprehensive analysis was undertaken on a total of 1886 publications. The analysis utilized GraphPad Prism 9, CiteSpace6.1.6, VOSviewer1.6.19, the Online Analysis Platform of Literature Metrology (http://bibliometric.com/), GeneMANIA (https://genemania.org/), and Metascape (https://metascape.org/gp/index.html#/main/step1).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We retrieved 2424 publications on hyaluronic acid (HA) and wound healing from the Web of Science Core Collection, covering the period from January 2000 to March 2024, and selected 1886 for analysis. The results show a significant increase in publications since 2016, reflecting a growing focus on this field. Currently, China's publication volume has surpassed the United States since 2017, indicating a significant rise in China's influence in this area. Using CiteSpace software for co-citation analysis, we identified eight main research clusters, including promoted wound healing, injured tissue, and advanced multi-targeted composite biomaterial. Key research areas involve the role and mechanisms of hyaluronic acid in tissue repair, particularly its applications in growth factor production and regenerative therapy. Analyzing keyword co-occurrence and burst data with VOSviewer, we identified research hotspots focused on biomaterials, such as nanoparticles and hydrogels, and their antibacterial properties. The keyword \"CD44\" showed a long burst period, while \"antibacterial\" had the highest burst intensity in 2022. We identified the top 21 genes extensively studied in hyaluronic acid and wound healing, including CD44, VEGF, and TGF-β. These genes are mainly involved in regulating cell migration, adhesion, proliferation, and cytokine activity. GO enrichment and KEGG pathway analyses indicate that these genes are associated with key signaling pathways, such as MAPK and EGFR, revealing the primary mechanisms hyaluronic acid promotes wound healing.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This pioneering study provides the first comprehensive bibliometric analysis of HA in wound healing. Covering the period from January 1, 2000 to March 31, 2024, it reveals a significant expansion in annual scholarly production. Current re","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70164"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Hsa_circ_0005085 May Suppress Cutaneous Squamous Cell Carcinoma Growth and Metastasis Through Targeting the MiR-186-5p/LAMC1 Axis.","authors":"","doi":"10.1111/srt.70181","DOIUrl":"https://doi.org/10.1111/srt.70181","url":null,"abstract":"","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70181"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: No Causal Association Between Atopic Dermatitis and COVID-19 Outcomes: A Mendelian Randomization Study.","authors":"","doi":"10.1111/srt.70182","DOIUrl":"https://doi.org/10.1111/srt.70182","url":null,"abstract":"","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70182"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Stimulus Temperature and Skin Hydration Levels on Wetness Perception at the Underarm.","authors":"Jade Ward, Emilio Verucchi, Dave Swaile, Katie Parker, Peter R Worsley, Davide Filingeri","doi":"10.1111/srt.70170","DOIUrl":"10.1111/srt.70170","url":null,"abstract":"<p><strong>Background: </strong>Experiencing wetness on the skin because of sweating or contact with fluids can induce thermal discomfort. Millions of people apply antiperspirant deodorant products to the underarm to minimise this negative experience. However, the mechanisms underpinning wetness perception at the underarm and the influence of underlying stratum corneum hydration remain under investigation. We aimed to evaluate the role of stimulus temperature and skin hydration levels on wetness perception at the underarm in young participants.</p><p><strong>Materials and methods: </strong>Ten healthy participants (5 M/5 F; 29 ± 7 years) underwent a quantitative sensory test during which they reported the perceived magnitude of wetness perception from a short-duration static application of a cold-wet (i.e., 5°C below local skin temperature), neutral-wet (i.e., equal to local skin temperature) and warm-wet (i.e., 5°C above local skin temperature) stimuli. Wetness perception was assessed on a 100-mm visual analogue scale (0 = dry; 100 = completely wet), with a repeated measures design exploring the effects of overhydration (+21 %) and dehydration (-40 %) of the underarm's skin.</p><p><strong>Results: </strong>Our results indicated a higher wetness perception (p = 0.012) during the cold-wet (40 mm, 95 % CI: 25, 56) than during the warm-wet (25 mm, 95 % CI: 12, 39), and neutral-wet stimuli (24 mm, 95 % CI: 7, 40). Furthermore, overhydration of the underarm' stratum corneum can lead to an increase in wetness perceptions upon contact with cold-wet stimuli only (mean increase: 20 mm, 95 % CI: 3, 36; p = 0.024; corresponding to 20 % increase).</p><p><strong>Conclusion: </strong>Our findings provide novel fundamental insights into the underarm's perceptual responses to wetness, which could inform understanding of the determinants of wet feel associated with periods of sweating and the application of antiperspirant products.</p>","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70170"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Revealing an Association Between HPV and Systemic Lupus Erythematosus: A Bidirectional Two-Sample Mendelian Randomization Study.","authors":"","doi":"10.1111/srt.70178","DOIUrl":"10.1111/srt.70178","url":null,"abstract":"","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70178"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Frontiers of Non-Invasive Detection in Scalp and Hair Diseases: A Review of the Application of Novel Detection Techniques.","authors":"Meijiao Du, Ying Wang, Jing Wang, Ying Xie, Yonglong Xu, Dingquan Yang","doi":"10.1111/srt.70163","DOIUrl":"https://doi.org/10.1111/srt.70163","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this paper is to review the current status and recent progress of the application of novel non-invasive testing technologies in the diagnosis, treatment, and care of scalp hair diseases in recent years, and to discuss their contribution to the improvement of scalp hair health management.</p><p><strong>Methods: </strong>Through a literature review, the principles and current status of application of technologies such as trichoscopy, microbiological testing, scalp skin physiological function testing, hair physiological index testing, and hair product patch testing, and their specific roles in the management of scalp hair diseases were systematically sorted out.</p><p><strong>Results: </strong>Trichoscopic intelligent analysis technology can quantitatively assess the hair growth status and provide an objective assessment of the efficacy of hair diseases; microbiological testing provides a laboratory reference for the rapid diagnosis of scalp diseases and clinical use of medication; scalp skin physiological function testing and hair physiological index testing are essential for a comprehensive assessment of the scalp environment and hair health. The patch test can effectively detect allergenic substances, which can help to safely select topical drugs and hair care products, avoid medical risks, and facilitate safety evaluation.</p><p><strong>Conclusion: </strong>Novel non-invasive testing techniques provide powerful technical support for accurate diagnosis, personalized treatment, and safe care of scalp hair diseases, and show a broad application prospect. Future research should focus on improving the accuracy and detection efficiency of these techniques to meet the growing demand for scalp hair health management and to promote the development of this field in a more scientific and refined direction.</p>","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70163"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}