Skin Research and Technology最新文献_第9页

RETRACTION: Identifying the Genetic Association Between Common Rheumatic Diseases and Vitiligo. 撤回：确定常见风湿病和白癜风之间的遗传关联。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70197

引用次数: 0

Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis. 在2,4-二硝基氯苯诱导的特应性皮炎小鼠模型中，多核苷酸增强皮肤屏障功能并减轻炎症。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70189

Ye Jin Ha, Ka Hee Tak, Jong Lyul Lee, Chan Wook Kim, Young-Chang Ah, Seok-Soon Kim, Ik Jun Moon, Yong Sik Yoon

{"title":"Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis.","authors":"Ye Jin Ha, Ka Hee Tak, Jong Lyul Lee, Chan Wook Kim, Young-Chang Ah, Seok-Soon Kim, Ik Jun Moon, Yong Sik Yoon","doi":"10.1111/srt.70189","DOIUrl":"10.1111/srt.70189","url":null,"abstract":"Background: Atopic dermatitis (AD) is a chronic inflammatory dermatological disorder characterized by skin barrier dysfunction, dry skin, pruritus, and aberrant immune responses to external stimuli. Although polynucleotides (PNs) have anti-inflammatory properties, their effect on AD remains unexplored.Materials and methods: This study investigated the effects of PNs on a 2,4-dinitrochlorobenzene (DNCB)-induced AD mouse model. The effects were evaluated by the dermatitis severity score (DSS), the spleen index, the serum immunoglobulin E (IgE) concentration, trans-epidermal water loss (TEWL), histological findings, and the expression levels of cytokine mRNA and filaggrin protein in skin tissue.Results: Topical application of PNs significantly reduced the DSS, the spleen index, the serum IgE concentration, and TEWL compared with the control. Additionally, histopathological analysis showed that PNs reduced epidermal and dermal thickness, the mast cell count, collagen deposition, and eosinophil infiltration in the dermis. Moreover, PNs significantly downregulated the expression of key inflammatory cytokines, including interleukin (IL)-4, IL-5, IL-13, IL-25, IL-33, and thymic stromal lymphopoietin (TSLP), in affected skin tissue. Immunohistochemical (IHC) staining and Western blot revealed that PNs inhibited DNCB-induced suppression of filaggrin. A combination of hyaluronic acid (HA) and PNs showed enhanced efficacy compared with PNs alone, particularly for reducing the serum IgE concentration and TEWL and increasing filaggrin expression.Conclusion: These results suggest that PNs are potential candidates to treat AD because they possess anti-inflammatory properties and improve skin barrier function.","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 6","pages":"e70189"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: The Causal Relationship between Immune Cells and Atopic Dermatitis: A Bidirectional Mendelian Randomization Study. 撤回：免疫细胞与特应性皮炎之间的因果关系：一项双向孟德尔随机研究。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70200

引用次数: 0

RETRACTION: Causal Effects of Genetically Determined Metabolites on Androgenetic Alopecia: A Two-Sample Mendelian Randomization Analysis. 撤回：基因决定代谢物对雄激素性脱发的因果影响：一项双样本孟德尔随机分析。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70202

引用次数: 0

RETRACTION: Horizontal Necklines Correction With Absorbable Braided Polydioxanone Threads: Case Series. 缩回：水平领口矫正与可吸收的编织聚二氧环酮线：案例系列。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70186

引用次数: 0

RETRACTION: Circ_0081054 Facilitates Melanoma Development via Sponging MiR-637 and Regulating RAB9A. 撤回：Circ_0081054通过海绵化MiR-637和调节RAB9A促进黑色素瘤的发展。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70204

引用次数: 0

RETRACTION: Correlation between Cigarette Smoking and Alcohol Consumption and Rosacea: A Two-Sample Mendelian Randomization Study. 撤回：吸烟和饮酒与酒渣鼻的相关性：一项双样本孟德尔随机研究。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-06-01 DOI: 10.1111/srt.70194

引用次数: 0

Short- and Long-Term Effects of Adding Topical Cosmetics to a Dermatological Procedure (Thermage): A Randomized Controlled Comparative Study Exploring the Synergistic Effects. 在皮肤手术（热疗）中添加局部化妆品的短期和长期影响：一项探索协同效应的随机对照比较研究。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-02-01 DOI: 10.1111/srt.70162

Sae-Ra Park, Ji-Yei Choi, Jangmi Suk, Byung-Fhy Suh, Eunjoo Kim

{"title":"Short- and Long-Term Effects of Adding Topical Cosmetics to a Dermatological Procedure (Thermage): A Randomized Controlled Comparative Study Exploring the Synergistic Effects.","authors":"Sae-Ra Park, Ji-Yei Choi, Jangmi Suk, Byung-Fhy Suh, Eunjoo Kim","doi":"10.1111/srt.70162","DOIUrl":"https://doi.org/10.1111/srt.70162","url":null,"abstract":"Background: Dermatological procedures improve skin changes caused by aging. However, few studies have focused on the effect of improving various skin characteristics compared with the concurrent use of cosmetics. We aimed to confirm changes in skin characteristics owing to anti-aging dermatological procedures in the short- and long-term and to determine the efficacy of the procedure when products with anti-aging and repair effects are used together.Materials and methods: We included 42 women (mean age, 47.667 ± 3.183 years) divided into a test (n = 21) and control (n = 21) group, with no history of dermatological procedures within 3 months of the test participation date. The dermatological procedure involved a single application of Thermage treatments, and products containing repair and anti-aging ingredients were used for the test group. The skin changes were assessed using device-based measurements and image analysis up to 4 weeks post-procedure.Results: Post-procedure side effects were alleviated 1 day after the procedure, and transepidermal water loss (TEWL) improved when the products were used together. Skin hydration, elasticity, density, fine lines, texture, and pores improved at 4 weeks after the procedure. When the test product was also used, the improvement was significantly greater, and TEWL of the face improved in the test group only. Aging-related skin characteristics were improved by Thermage, and the combined use of test products and procedures with repair and anti-aging effects improved skin characteristics.Conclusion: Dermatological procedures and cosmetic products have internal and external anti-aging effects on the skin, respectively, resulting in synergy.","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 2-5","pages":"e70162"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Abnormal Brain Structure in Atopic Dermatitis: Evidence From Mendelian Randomization Study. 撤回：特应性皮炎的脑结构异常：来自孟德尔随机化研究的证据。

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-02-01 DOI: 10.1111/srt.70183

引用次数: 0

RETRACTION: LncRNA NEAT1 Targets MiR-125/ADAM9 Mediated NF-κB Pathway in Inflammatory Response of Rosacea. 撤下：LncRNA NEAT1靶向MiR-125/ADAM9介导的NF-κB通路在酒渣鼻炎症反应中的作用

IF 2 4区医学

Skin Research and Technology Pub Date : 2025-02-01 DOI: 10.1111/srt.70185

引用次数: 0