{"title":"Radiation-Induced Acquired Lacrimal Drainage Obstructions: Management and Outcomes.","authors":"Nandini Bothra, Lisa Y Lin, Michael K Yoon","doi":"10.1080/08820538.2024.2376620","DOIUrl":"https://doi.org/10.1080/08820538.2024.2376620","url":null,"abstract":"<p><strong>Objective: </strong>To describe the management and outcomes of patients with radiation-induced acquired lacrimal duct obstructions (RALDO).</p><p><strong>Methods: </strong>A retrospective chart review from July 2018 to December 2023 of all cases undergoing surgical intervention for RALDO by a single surgeon. Data collected included demographics, tumor type and anatomic location, radiation treatment (including radiation type, dosage, and duration), interval between radiation and reported onset of epiphora, oculoplastic clinical examination, management, and outcomes. Lacrimal irrigation was done prior to surgery in all patients.</p><p><strong>Results: </strong>Seventeen eyes of 16 patients with a mean age at presentation of 63.3 years and over half the patients being females (56.3%) were included in the study. The right lacrimal drainage system (LDS) was involved in 4 (23.6%), and the left side was involved in 13 (76.4%). The mean onset of epiphora symptoms after radiation was 9.5 months. The underlying tumor type were intraocular having uveal melanoma in four, cutaneous squamous cell carcinoma in 2, basal cell carcinoma involving forehead and nose in one and sino-nasal indications present in 8 patients. One patient had metastasis to the orbit and eyelid. Four patients (25%) received external beam radiotherapy (XRT) (one case had bilateral LDS involvement), 6 patients (37.5%) received intensity-modulated radiation therapy (IMRT), 5 patients (31.25%) received proton beam irradiation (PBI), and one (6.25%) received stereotactic body radiotherapy (SBRT). Mean radiation dosage was 61.31 Gy in 15 patients (data was missing in 1 patient). Punctum was effaced in 3, canalicular stenosis in 1, proximal canalicular obstruction in 8, distal canalicular obstruction in 2, and nasolacrimal duct obstruction (NLDO) in 3. Treatment was based on the site and nature of obstruction and varied from minimally invasive techniques like serial dilatation with bicanalicular silicone tube or Guibor tube to surgical interventions like dacryocystorhinostomy (DCR) or conjunctivo-dacryocystorhinostomy (C-DCR). Only 10% with primary lacrimal intubation had good response. Of the six cases that underwent C-DCR with Jones tube either as primary or secondary procedure, four cases showed improvement in epiphora (67%). Three with NLDO did well after external DCR. In total, four patients had a secondary procedure after the first failed while 7 with failed initial surgery elected against secondary surgery. The mean follow-up was 9.6 months (range 2-24 months).</p><p><strong>Conclusions: </strong>In patients with RALDO, salvage treatment with silicone lacrimal intubation has poor results, CDCR with Jones tube has better results, although imperfect and in cases with NLDO, DCR has good outcomes.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad M Shamim, Sam Karimaghaei, Riley Sanders, Sami H Uwaydat, Ahmed B Sallam
{"title":"Phacofragmentation of Posteriorly Dislocated Lens Fragments: Limbal versus Pars Plana Approach.","authors":"Muhammad M Shamim, Sam Karimaghaei, Riley Sanders, Sami H Uwaydat, Ahmed B Sallam","doi":"10.1080/08820538.2024.2376630","DOIUrl":"https://doi.org/10.1080/08820538.2024.2376630","url":null,"abstract":"<p><strong>Purpose: </strong>To assess intra-operative complications and feasibility of removing crystalline lens fragments from the vitreous cavity through a limbal incision compared to a pars plana approach.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Subjects: </strong>16 eyes underwent phacofragmentation via a limbal approach (Group A) and 9 eyes through a pars plana approach (Group B) at an academic center over a 10-year period.</p><p><strong>Methods: </strong>We collected pre-operative, intra-operative, and post-operative data. We compared rates of intraoperative complications, including corneal wound burn, iris or capsular damage, retinal tears, and hemorrhage, and recorded post-operative BCVA and IOP measurements at the one-month post-operative appointment. We also compared rates of post-operative complications, including corneal edema, choroidal detachment, or retinal detachment.</p><p><strong>Main outcome measures: </strong>Primary outcomes of the study were the rates of intraoperative complications and the feasibility of crystalline lens removal with the limbal approach. We defined the latter outcome as the ability to complete lens removal without switching to the pars plana route.</p><p><strong>Results: </strong>Mean BCVA for group A was 1.6, and for group B was 2.0 (<i>p</i> = .19). There was no significant difference between the two groups in the incidence of intraoperative complications, including corneal wound burn, iris damage, anterior capsular tear, iatrogenic retinal tear, or suprachoroidal hemorrhage (<i>p</i> > .99). There was no significant difference in the incidence of intra-operative vitreous hemorrhage (<i>p</i> = .36). Additionally, there was no significant difference in post-operative corneal edema (<i>p</i> = .27), choroidal detachment (<i>p</i> = .52), or retinal detachment (<i>p</i> > .99). The mean post-operative BCVA was 1.0 in group A and 1.0 in group B (<i>p</i> = .75). We completed all cases in group A using the limbal approach without switching to the pars plana route.</p><p><strong>Conclusion: </strong>Phacofragmentation through a limbal incision provides a feasible option for dropped nuclear fragment removal and is not associated with a higher risk of complications than the pars plana route.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Learning Curve in Posterior Segment Ophthalmic Diagnostic Endoscopy: Implications for Budding Enthusiasts and Fellows-In-Training.","authors":"Vivek Pravin Dave, Ramya Natarajan, Rajeev Reddy Pappuru","doi":"10.1080/08820538.2024.2373269","DOIUrl":"https://doi.org/10.1080/08820538.2024.2373269","url":null,"abstract":"<p><strong>Purpose: </strong>To elucidate the learning curve for posterior segment diagnostic endoscopy (DE) based on the results of a self-trained (ST) and a supervised (SUP) vitreoretinal surgeon.</p><p><strong>Methods: </strong>Retrospective review of medical records of DE performed between 2017 and 2023 by one ST and one SUP vitreoretinal surgeon at a tertiary eye care institute. Data were collected and the serial number of cases was plotted against the time taken for the procedure. A comparative regression plot was created for both the surgeons to know the slope of the learning curve. The start time was noted as that of attachment of the endoscope and the stop time was noted as the end of diagnostic evaluation. Procedures were divided into blocks of 10 cases each and the time taken for the procedures was calculated.</p><p><strong>Results: </strong>Total of 106 eyes (58 by ST surgeon and 48 by SUP surgeon) were included. For ST surgeon, the time taken for the surgery correlated inversely (reduced sequentially) with the serial number of the case till the 20<sup>th</sup> case (correlation coefficient = -0.5, <i>p</i> = .01), for SUP surgeon, the time taken for the surgery correlated inversely with the serial number of the case till the 10<sup>th</sup> case (correlation coefficient = -0.9, <i>p</i> = <0.0001) and then stabilized. Neither of the groups had any adverse events.</p><p><strong>Conclusion: </strong>About 20 cases for a self-trained and about 10 cases for a supervised vitreoretinal surgeon are required to get stable with DE. These observations have implications in creating a training module for DE with appropriate number of training cases.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141580756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-02-28DOI: 10.1080/08820538.2024.2322428
Khaled Moustafa
{"title":"Variations in Citations Across Databases: Implications for Journal Impact Factors.","authors":"Khaled Moustafa","doi":"10.1080/08820538.2024.2322428","DOIUrl":"10.1080/08820538.2024.2322428","url":null,"abstract":"<p><p>The Journal Impact Factor (JIF) is a widely used metric for ranking journals based on the number of citations garnered by papers published over a specific timeframe. To assess the accuracy of JIF values, I compared citation counts for 30 of my own publications across six major bibliography databases: CrossRef, Web of Science, Publisher records, Google Scholar, PubMed and Scopus. The analysis revealed noteworthy variations in citation counts, ranging from 10% to over 50% between the lowest and highest citation counts. Google Scholar records the highest citation numbers, while PubMed reported the lowest. Notably, Web of Science, whose citation data are used in JIF calculations, tend to underestimate citation counts compared to other databases. These observations raise concerns about the accuracy of JIF calculation based on Web of Science's citation data. The real JIF values for most journals would differ from those annually reported by Clarivate's journal citation reports (JCR). These citation discrepancies underscore the importance of comprehensive data collection and the necessity to include additional citation sources. Not because a paper is cited in one journal rather than another should it have a less or more citation weight. Ultimately, one citation remains one citation, regardless of its origin. Clarivate Analytics may thus need to consider integrating all citation sources for more accurate JIF values. Alternatively, Google Scholar could potentially develop its own journal or citation impact based on its extensive journal citation records. However, while making adjustments to how the Journal Impact Factor is calculated can make it more mathematically precise, it doesn't address the fundamental biases built into the metric. Even with refinements, the Journal Impact Factor will remain skewed due to how it's defined and used.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139983691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-03-19DOI: 10.1080/08820538.2024.2322452
Giovanni Aulino, Federico Giannuzzi, Matteo Mario Carlà, Giorgia Guarnieri, Domenico Spagnolo, Domenico Lepore, Francesca Cittadini, Stanislao Rizzo
{"title":"Taser-Related Ocular Injuries: A Review of the Literature and Medico-Legal Implications.","authors":"Giovanni Aulino, Federico Giannuzzi, Matteo Mario Carlà, Giorgia Guarnieri, Domenico Spagnolo, Domenico Lepore, Francesca Cittadini, Stanislao Rizzo","doi":"10.1080/08820538.2024.2322452","DOIUrl":"10.1080/08820538.2024.2322452","url":null,"abstract":"<p><strong>Purpose: </strong>Electric weapons have dangers associated with their use, such as burns and trauma related with the impacts of uncontrolled falls, even though they often minimize morbidity and mortality. The exact visual outcome of the damage inflicted is unknown, even though numerous studies have been documented in the literature about the ocular damage induced by the use of these tools.</p><p><strong>Methods: </strong>We present a narrative review of types of eye damage associated with the use of the Taser. The following search terms were used to identify eligible articles through the PubMed database: \"TASER\", \"Conducted Electric Weapons\", \"CEWs\".</p><p><strong>Results: </strong>A total of 15 articles were included with information about 38 patients with eye damage associated with the use of taser. The majority of patients were males. In most cases the mechanism of injury was the penetration of the probe inside the eye. Clinical manifestations of ocular damage were present in only 18 out of 38 cases and varied according to the type of damage mechanism. Indeed, the cases in which the probe had penetrated the eye showed more severe clinical manifestations with a poor visual outcome.</p><p><strong>Conclusion: </strong>In conclusion, the introduction of taser use for law enforcement requires serious consideration and adequate training for officers.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140158969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-03-11DOI: 10.1080/08820538.2024.2322443
Marko Oydanich, Aditya Uppuluri, Hadeel Sadek, Albert S Khouri
{"title":"Corneal Hysteresis as a Marker for Patients with Secondary Glaucoma.","authors":"Marko Oydanich, Aditya Uppuluri, Hadeel Sadek, Albert S Khouri","doi":"10.1080/08820538.2024.2322443","DOIUrl":"10.1080/08820538.2024.2322443","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate and compare the association of corneal hysteresis (CH) in patients with secondary glaucoma to control patients and patients with primary open-angle glaucoma (POAG). Additionally, to determine the consistency of CH measurements in patients with secondary glaucoma.</p><p><strong>Methods: </strong>A total of 84 patients (121 eyes) were prospectively included in this study. Twenty-three patients (46 eyes) were healthy controls, 24 patients (40 eyes) were diagnosed with POAG, and 27 patients (35 eyes) were diagnosed with a form of secondary glaucoma. CH and intraocular pressure (IOP) were measured using the Ocular Response Analyzer. Three measurements per eye were performed and used for the analysis and to determine fluctuations in CH data. One-way ANOVA with post-hoc Bonferroni analysis and Chi-Squared testing was done to determine differences between groups.</p><p><strong>Results: </strong>All patients were matched for age. Patients in both POAG and secondary glaucoma groups were matched for age and IOP. All groups had similar sex and racial compositions as well as similar proportions of diabetes, hypertension, and hyperlipidemia. CH was lower (<i>p</i> < .05) in patients with POAG (9.32 ± 1.64) and secondary glaucoma (7.89 ± 3.18) when compared to healthy controls (11.16 ± 1.60). Fluctuations in CH measurements were minimal in all groups. Further analysis of the secondary glaucoma group revealed no differences in CH between different types of secondary glaucoma (<i>p</i> > .05).</p><p><strong>Conclusion: </strong>Patients with secondary glaucoma have lower CH when compared to POAG or control groups. The ORA exhibits precision of CH measurements for control, POAG, and secondary glaucoma groups, making it a reliable tool in management of secondary forms of glaucoma.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-05-29DOI: 10.1080/08820538.2024.2348326
{"title":"Correction.","authors":"","doi":"10.1080/08820538.2024.2348326","DOIUrl":"https://doi.org/10.1080/08820538.2024.2348326","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-02-27DOI: 10.1080/08820538.2024.2324070
Lixin Sun, Ruchen Peng, Rongxin Sun
{"title":"New Multi-Parameters Combination of Technetium-99m-Diethylene-Triamine-Pentaacetate Orbital Single-Photon Emission Computed Tomography/Computed Tomography for the Evaluation of Graves' Orbitopathy Activity.","authors":"Lixin Sun, Ruchen Peng, Rongxin Sun","doi":"10.1080/08820538.2024.2324070","DOIUrl":"10.1080/08820538.2024.2324070","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the new combined parameters of <sup>99m</sup>Tc-DTPA orbital single-photon emission computed tomography/computed tomography (SPECT/CT) for the evaluation of Graves' orbitopathy (GO) activity.</p><p><strong>Methods: </strong>A retrospective analysis was performed on 41 patients. All the patients undergone the 99mTc-DTPA orbital SPECT/CT and were categorized into active and inactive group based on the standard combined by the clinical active score (CAS), magnet resonance imaging (MRI) and/or follow-up results. Quantitative parameters of lacrimal gland (LG) including the protruding degree of lacrimal gland herniation (LGH) and uptake ratios (URs) of region of interest (ROI) drawn on lacrimal gland and occipital bone. SPECT/CT reading results were based on visual analysis. Parameters were compared between the two groups and the diagnostic value on discrimination of GO activity was also evaluated.</p><p><strong>Results: </strong>All parameters of SPECT/CT for active GO groups were significantly higher than those of the inactive groups (<i>p</i><.05). There were notable linear positive correlations between the assumption standard and readings as well as combination models 2 and 3 (<i>r</i> = .794, <i>r</i> = .772, <i>r</i> = .760, respectively). ROC analysis indicated that model 2 provided the highest diagnostic performance, exhibiting an area under the curve (AUC) of .947, a sensitivity of 92.7%, and a specificity of 88.6%.</p><p><strong>Conclusions: </strong>The combined use of SPECT/CT reading results and DTPA uptake parameters of LG offers a more objective and precise evaluation of active GO. This study further recommends <sup>99m</sup>Tc-DTPA SPECT/CT might be serving as a supplementary beneficial approach for CAS in evaluating GO activity.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139973353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-03-01DOI: 10.1080/08820538.2024.2324074
Luis Leal-Vega, David P Piñero, Ainhoa Molina-Martín, Carlos J Hernández-Rodríguez, Rubén Cuadrado-Asensio, Adrián Martín-Gutiérrez, Juan Francisco Arenillas Lara, María Begoña Coco Martín
{"title":"Pilot Study Assessing the Safety and Acceptance of a Novel Virtual Reality System to Improve Visual Function.","authors":"Luis Leal-Vega, David P Piñero, Ainhoa Molina-Martín, Carlos J Hernández-Rodríguez, Rubén Cuadrado-Asensio, Adrián Martín-Gutiérrez, Juan Francisco Arenillas Lara, María Begoña Coco Martín","doi":"10.1080/08820538.2024.2324074","DOIUrl":"10.1080/08820538.2024.2324074","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the feasibility of the clinical use of a novel Virtual Reality (VR) training software designed to be used for active vision therapy in amblyopic patients by determining its preliminary safety and acceptance on the visual function of healthy adults.</p><p><strong>Methods: </strong>Pilot study enrolling 10 individuals (3 men, 7 women, mean age: 31.8 ± 6.5 years) with a best-corrected visual acuity (BCVA) of ≥ .90 (decimal) in both eyes were evaluated before and after 20 minutes of exposure to the NEIVATECH VR system using the HTC Vive Pro Eye head mounted display. Visual function assessment included near (40 cm) and distance (6 m) cover test (CT), stereopsis, binocular accommodative facility (BAF), near point of convergence (NPC), near point of accommodation (NPA), accommodative-convergence over accommodation (AC/A) ratio and positive and negative fusional vergences. Safety was assessed using the VR Sickness Questionnaire (VRSQ) and acceptance using the Technology Acceptance Model ;(TAM). Changes in all these variables after VR exposure were analyzed.</p><p><strong>Results: </strong>Short-term exposure to the NEIVATECH VR system only induced statistically significant changes in distance phoria (<i>p</i> = .016), but these changes were not clinically relevant. No significant changes were observed in VRSQ oculo-motricity and disorientation scores after exposure (<i>p</i> = .197 and .317, respectively). TAM scores showed a good acceptance of the system in terms of perceived enjoyment and perceived ease of use, although some concerns were raised in relation to the intention-to-use domain.</p><p><strong>Conclusion: </strong>Exposure to the NEIVATECH VR system does not seem to adversely affect the visual function in healthy adults and its safety and acceptance profile seems to be adequate for supporting its potential use in other populations, such as amblyopic patients.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139997391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seminars in OphthalmologyPub Date : 2024-07-01Epub Date: 2024-03-11DOI: 10.1080/08820538.2024.2323113
Mona Mahmoud Elsakka, Mostafa Hossam El Din Moawad, Eman E Labeeb, Mohamed Elneny, Abdelmonem Siddiq, Shereen Gahlan, Ibraheem M Alkhawaldeh, Hashem Abu Serhan
{"title":"Chorioretinopathy Post COVID-19: A Systematic Review and Prevalence Assessment, Unveiling Insights into an Emerging Ocular Entity.","authors":"Mona Mahmoud Elsakka, Mostafa Hossam El Din Moawad, Eman E Labeeb, Mohamed Elneny, Abdelmonem Siddiq, Shereen Gahlan, Ibraheem M Alkhawaldeh, Hashem Abu Serhan","doi":"10.1080/08820538.2024.2323113","DOIUrl":"10.1080/08820538.2024.2323113","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the occurrence of chorioretinopathy post-COVID-19, emphasizing demographic characteristics, medication history, clinical presentation, diagnostic evaluation, and treatment approaches, with a specific focus on the role of corticosteroid use.</p><p><strong>Methods: </strong>Our protocol was registered prospectively on PROSPERO (CRD42023457712). A systematic search of databases (PubMed, Cochrane, WOS, Scopus) from November 2020 to August 2023 were performed to identify any original research reporting chorioretinopathy in COVID-19 patients. Data extraction included patient demographics, COVID-19 timeline, medication history, symptoms, diagnostic tests, and treatment outcomes. We used Joanna Briggs Institute (JBI) critical appraisal tool to assess the quality of our included studies.</p><p><strong>Results: </strong>We identified seven case reports and two case series including 10 patients, six females and four males (mean age 36.5 years), who exhibited chorioretinopathy after COVID-19. Onset varied from 6 days to three months post-infection (average = 24.3 days). Seven patients (70%) had a history of corticosteroid use during COVID-19 treatment. Symptoms included visual loss, blurred vision, and deterioration. Diagnostic assessments revealed central serous chorioretinopathy in seven patients (70%) and punctate inner choroidopathy in two (20%). Treatment approaches varied, with corticosteroid discontinuation leading to symptom improvement, while two patients were treated with corticosteroids. Five patients who discontinued corticosteroids were reported to have improvement in visual acuity, two of them changed to 20/25 after being 20/40, two changed to 6/6, and one changed to 20/20, while the visual acuity in the sixth patient was not reported. Regarding the two patients who were treated with corticosteroids, visual acuity was reported in one case only and it improved to 20/20.</p><p><strong>Conclusion: </strong>This systematic review states the prevalence and potential association between chorioretinopathy, and corticosteroid use in the context of COVID-19. This relation is still unclear because of the relief of symptoms in some cases after corticosteroid discontinuation, while two other cases were treated with corticosteroids and their symptoms improved.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}