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Ruthenium-106 Plaque Brachytherapy for the Management of Intraocular Tumors in Thailand: The First Report from Southeast Asia. 钌-106斑块近距离放射治疗泰国眼内肿瘤：来自东南亚的第一份报告。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-10-01 Epub Date: 2024-12-30 DOI: 10.1080/08820538.2024.2448522
Thanaporn Kritfuangfoo, Boontip Tipsuriyaporn, Thitiporn Thongborisuth, Daranee Piriyasang, Somjai Dangprasert, Ladawan Narkwong, Duangnate Rojanaporn
{"title":"Ruthenium-106 Plaque Brachytherapy for the Management of Intraocular Tumors in Thailand: The First Report from Southeast Asia.","authors":"Thanaporn Kritfuangfoo, Boontip Tipsuriyaporn, Thitiporn Thongborisuth, Daranee Piriyasang, Somjai Dangprasert, Ladawan Narkwong, Duangnate Rojanaporn","doi":"10.1080/08820538.2024.2448522","DOIUrl":"10.1080/08820538.2024.2448522","url":null,"abstract":"<p><strong>Background: </strong>Report the results of Ruthenium plaque brachytherapy (<sup>106</sup>Ru) for the management of intraocular tumors in Thailand.</p><p><strong>Methods: </strong>We retrospectively reviewed the medical records of 46 eyes of 45 patients who received <sup>106</sup>Ru brachytherapy for the treatment of various intraocular tumors in the Department of Ophthalmology of Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, between April 2013 and December 2020.</p><p><strong>Results: </strong>Of 46 eyes, 21 (46%) were diagnosed with small to medium choroidal melanoma, 13 (28%) with retinoblastoma, 4 (9%) with choroidal metastases, 2 (4%) with retinal vasoproliferative tumor (VPT), 3 (7%) with choroidal hemangioma (CH), 2 (4%) with RPE adenoma, and 1 (2%) with retinal hemangioblastoma. The mean tumor thickness was 4.8 mm (range, 2.4-6.6). After a mean follow-up of 62.4 months (range, 4.8-122.7), local tumor control was achieved in 39 eyes (85%), which were 100% for choroidal melanoma, 46% for RB, 100% for choroidal metastasis and 100% for benign tumors. Radiation-related complications were found in 28 eyes (61%), including cataracts in 10 (25%), radiation retinopathy in 14 (30%), radiation maculopathy in 14 (30%), radiation papillopathy in 6 (13%), and vitreous hemorrhage in 3 (7%) eyes. All patients with retinoblastoma currently alive without metastasis. Two patients with choroidal melanoma developed systemic metastases and three patients with choroidal metastases died at the end of the study.</p><p><strong>Conclusions: </strong>Patients with intraocular tumors treated with <sup>106</sup>Ru brachytherapy showed excellent outcomes in relation to tumor control with few complications.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":"40 7","pages":"650-658"},"PeriodicalIF":2.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 16: Doyens of Dacryology Series - Charles de Saint-Yves (1667-1736) and His Observations on Anchylops and Aegilops. 泪史-第16部分：泪史系列-圣伊夫（1667-1736）和他对鳀鱼和Aegilops的观察。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-04-29 DOI: 10.1080/08820538.2025.2496100
Mohammad Javed Ali
{"title":"Lacrimal History - Part 16: Doyens of Dacryology Series - Charles de Saint-Yves (1667-1736) and His Observations on Anchylops and Aegilops.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2496100","DOIUrl":"10.1080/08820538.2025.2496100","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"596-599"},"PeriodicalIF":2.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Episcleral Plaque Brachytherapy. 巩膜斑块近距离放疗。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-03-21 DOI: 10.1080/08820538.2025.2480189
Vishal Raval, Rohan Kapoor, Arun Singh
{"title":"Episcleral Plaque Brachytherapy.","authors":"Vishal Raval, Rohan Kapoor, Arun Singh","doi":"10.1080/08820538.2025.2480189","DOIUrl":"10.1080/08820538.2025.2480189","url":null,"abstract":"<p><strong>Background: </strong>Episcleral plaque brachytherapy is a treatment method for ocular tumors that involves placing radionuclide sources directly on or around the tumor using an episcleral plaque. This technique offers the advantage of a highly focused radiation dose, minimizing exposure to critical eye structures. Various radionuclides such as I-125, Ru-106, and Pd-103 are used in ocular brachytherapy. The choice of radionuclides depends on several factors, such as tumor size, location, and desired dose rate.</p><p><strong>Methods: </strong>A retrospective review of the literature from PubMed (1998-2024).</p><p><strong>Results: </strong>Special emphasis is placed on indications for ocular brachytherapy and variations in treatment approaches for choroidal and retinal tumors. This article provides a comprehensive overview of ocular brachytherapy, focusing on its history, indications, technique, and complications. It also provides insight into new innovations in ocular brachytherapy.</p><p><strong>Conclusion: </strong>This article highlights the indications for ocular brachytherapy in choroidal and retinal tumors and describes its complications. This review of the literature on synthesized variations in treatment approaches was conducted to identify the most commonly used management strategies.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"634-641"},"PeriodicalIF":2.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 64: Doyens of Dacryology Series - Cornelius Rea Agnew (1830-1888): Agnew's Knife, Punctocanaliculoplasty, and Cautery of the Lacrimal Sac Epithelium. 泪史-第64部分：泪学系列的几十年- Cornelius Rea Agnew (1830-1888): Agnew的刀，泪囊上皮的小管成形术和烧灼。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-25 DOI: 10.1080/08820538.2025.2566595
Mohammad Javed Ali
{"title":"Lacrimal History - Part 64: Doyens of Dacryology Series - Cornelius Rea Agnew (1830-1888): Agnew's Knife, Punctocanaliculoplasty, and Cautery of the Lacrimal Sac Epithelium.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2566595","DOIUrl":"https://doi.org/10.1080/08820538.2025.2566595","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-5"},"PeriodicalIF":2.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orbital Apex Syndrome Secondary to Herpes Zoster Ophthalmicus: A Literature Review and In-Depth Understanding. 眼带状疱疹继发眼眶尖综合征：文献回顾及深入了解。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-25 DOI: 10.1080/08820538.2025.2559843
Robin Dupré, Jean-Philippe Grosse, Stéphanie Baillif, Charles Philippe, Alexandra Rabot, Lydiane Mondot, Nathalie Tieulié, Arnaud Martel
{"title":"Orbital Apex Syndrome Secondary to Herpes Zoster Ophthalmicus: A Literature Review and In-Depth Understanding.","authors":"Robin Dupré, Jean-Philippe Grosse, Stéphanie Baillif, Charles Philippe, Alexandra Rabot, Lydiane Mondot, Nathalie Tieulié, Arnaud Martel","doi":"10.1080/08820538.2025.2559843","DOIUrl":"https://doi.org/10.1080/08820538.2025.2559843","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report our experience and to provide a comprehensive understanding of the onset and course of orbital apex syndrome secondary to herpes zoster ophthalmicus (HZO-OAS).</p><p><strong>Methods: </strong>A retrospective study was conducted in Nice University Hospital and Antibes Hospital (France) between January 2020 and December 2023. All patients diagnosed with HZO-OAS with at least a 1-month follow-up were included.</p><p><strong>Results: </strong>Eight patients with a mean age of 81 (73-90) years were included. Half of the patients had underlying immunosuppression. The mean time between the onset of the vesicular rash and the development of HZO-OAS was 10 (2-19) days. HZO-OAS occurred while all patients were already treated with oral valacyclovir. The mean initial best-corrected visual acuity (BCVA) was 20/1093. All patients had concomitant ocular involvement, i.e. keratitis, anterior uveitis or both. Seven (87.5%) patients had optic neuritis. All patients were treated with intravenous acyclovir at neuro-meningeal doses. Oral steroids were prescribed in 62.5% of patients with gradual tapering. The mean BCVA was 20/87 at 3 months. Almost all patients experienced a complete resolution of ophthalmoplegia and ptosis at 3 months. Residual mydriasis was observed in 37.5% of patients. We proposed a schematic diagram describing the course of HZO-OAS.</p><p><strong>Conclusion: </strong>HZO-OAS is a rare but devastating complication occurring mainly in older and immunosuppressed patients despite treatment with oral antivirals. Early identification and treatment with intravenous acyclovir combined with steroids appear to be essential.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-12"},"PeriodicalIF":2.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 56: Doyens of Dacryology Series - The Clinicoanatomical Works of Joseph von Gerlach (1820-1896), Heinrich Heinlein, Jean Riolan (1577-1657), and Florent Cunier (1812-1853). 泪史-第56部分：泪学系列——约瑟夫·冯·格拉赫（1820-1896）、海因里希·海因莱因、让·里奥兰（1577-1657）和弗洛伦特·库尼尔（1812-1853）的临床解剖作品。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-24 DOI: 10.1080/08820538.2025.2566600
Mohammad Javed Ali
{"title":"Lacrimal History - Part 56: Doyens of Dacryology Series - The Clinicoanatomical Works of Joseph von Gerlach (1820-1896), Heinrich Heinlein, Jean Riolan (1577-1657), and Florent Cunier (1812-1853).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2566600","DOIUrl":"https://doi.org/10.1080/08820538.2025.2566600","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-9"},"PeriodicalIF":2.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 50: Doyens of Dacryology Series - The Surgical Treatises of Dominique Anel (1679-1730) and His Concepts of the Dropsy of the Lacrimal Ducts. 泪道史-第50部分：泪道学系列-多米尼克·阿内尔（1679-1730）的外科论文和他的泪道水肿的概念。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-22 DOI: 10.1080/08820538.2025.2565076
Mohammad Javed Ali
{"title":"Lacrimal History - Part 50: Doyens of Dacryology Series - The Surgical Treatises of Dominique Anel (1679-1730) and His Concepts of the Dropsy of the Lacrimal Ducts.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2565076","DOIUrl":"https://doi.org/10.1080/08820538.2025.2565076","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-5"},"PeriodicalIF":2.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 60: Doyens of Dacryology Series - Emil Huschke (1797-1858) and His Concepts of the Lacrimal Drainage Anatomy. 泪史-第60部分：泪学系列的几十年-埃米尔Huschke（1797-1858）和他的泪道引流解剖学的概念。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-22 DOI: 10.1080/08820538.2025.2565077
Mohammad Javed Ali
{"title":"Lacrimal History - Part 60: Doyens of Dacryology Series - Emil Huschke (1797-1858) and His Concepts of the Lacrimal Drainage Anatomy.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2565077","DOIUrl":"https://doi.org/10.1080/08820538.2025.2565077","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-4"},"PeriodicalIF":2.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 57: Doyens of Dacryology Series - Anel's Fight Back Through Correspondence and His Apologetic Discourse. 泪史-第57部分：泪学系列的几十年-阿尼尔通过书信的反击和他的道歉话语。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-17 DOI: 10.1080/08820538.2025.2562767
Mohammad Javed Ali
{"title":"Lacrimal History - Part 57: Doyens of Dacryology Series - Anel's Fight Back Through Correspondence and His Apologetic Discourse.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2562767","DOIUrl":"https://doi.org/10.1080/08820538.2025.2562767","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-8"},"PeriodicalIF":2.3,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal History - Part 54: Doyens of Dacryology Series - Jean-Paul Adenis (1947-). 泪史-第54部分：泪学系列-让-保罗·阿德尼斯（1947-）。
IF 2.3 4区 医学
Seminars in Ophthalmology Pub Date : 2025-09-17 DOI: 10.1080/08820538.2025.2562768
Mohammad Javed Ali, Bhupendra C K Patel
{"title":"Lacrimal History - Part 54: Doyens of Dacryology Series - Jean-Paul Adenis (1947-).","authors":"Mohammad Javed Ali, Bhupendra C K Patel","doi":"10.1080/08820538.2025.2562768","DOIUrl":"https://doi.org/10.1080/08820538.2025.2562768","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-4"},"PeriodicalIF":2.3,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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