Seminars in Ophthalmology最新文献

{"title":"Lacrimal History - Part 27: Doyens of Dacryology Series - Geoffrey Edward Rose (1955-).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2460364","DOIUrl":"10.1080/08820538.2025.2460364","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"159-161"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Trends and Hotspots of Big Data in Ophthalmology: A Bibliometric Analysis and Visualization.","authors":"Jiawei Chen, Xiang-Ling Yuan, Zhimin Liao, Wenxiang Zhu, Xiaoyu Zhou, Xuanchu Duan","doi":"10.1080/08820538.2024.2421478","DOIUrl":"10.1080/08820538.2024.2421478","url":null,"abstract":"<p><strong>Purpose: </strong>The burst of modern information has significantly promoted the development of global medicine into a new era of big data healthcare. Ophthalmology is one of the most prominent medical specialties driven by big data analytics. This study aimed to describe the development status and research hotspots of big data in ophthalmology.</p><p><strong>Methods: </strong>English articles and reviews related to big data in ophthalmology published from January 1, 1999, to April 30, 2024, were retrieved from the Web of Science Core Collection. The relevant information was analyzed and visualized using VOSviewer and CiteSpace software.</p><p><strong>Results: </strong>A total of 406 qualified documents were included in the analysis. The annual number of publications on big data in ophthalmology reached a rapidly increasing stage since 2019. The United States (<i>n</i> = 147) led in the number of publications, followed by India (<i>n</i> = 77) and China (<i>n</i> = 69). The L.V. Prasad Eye Institute in India was the most productive institution (<i>n</i> = 50), and Anthony Vipin Das was the most influential author with the most relevant literature (<i>n</i> = 45). The electronic medical records were the primary source of ophthalmic big data, and artificial intelligence served as the principal analytics tool. Diabetic retinopathy, glaucoma, and myopia are currently the main topics of interest in this field.</p><p><strong>Conclusions: </strong>The application of big data in ophthalmology has experienced rapid growth in recent years. Big data is expected to play an increasingly significant role in shaping the future of research and clinical practice in ophthalmology.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"210-222"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142507450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 11: Doyens of Dacryology Series - Johann Gottfried Zinn (1727-1759) and his Anatomy Treatise of 1755.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2024.2422224","DOIUrl":"10.1080/08820538.2024.2422224","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"153-155"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 26: Doyens of Dacryology Series - George Brian Bartley (1955-).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2024.2435695","DOIUrl":"10.1080/08820538.2024.2435695","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"156-158"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitrectomy Combined with Repeated Intravitreal Injection of Ceftazidime for the Treatment of Brucellosis Endophthalmitis: A Case Report and Literature Review.","authors":"Nan Guo, Yu-Jia Gui, Ying Chen","doi":"10.1080/08820538.2024.2412050","DOIUrl":"10.1080/08820538.2024.2412050","url":null,"abstract":"<p><strong>Purpose: </strong>To present a treatment regimen for Brucellosis endophthalmitis that resulted in a good visual outcome. Additionally, we conducted a literature review on the treatment and visual prognosis of related cases.</p><p><strong>Case presentation: </strong>A 49-year-old woman with the chief complaint of decreased vision and redness in the right eye was initially diagnosed with noninfectious uveitis and prescribed high-dose steroids which led to transient improvement followed by a decline in vision. An infectious cause was suspected. Metagenomic next-generation sequencing of vitreous fluid and serological testing confirmed Brucella melitensis infection. The patient underwent vitrectomy combined with six intravitreal injections of ceftazidime in the right eye in addition to systemic antibiotic treatment. The intraocular inflammation was completely resolved, and the visual acuity recovered to 20/25, which is the best-documented recovery in Brucella endophthalmitis cases, as revealed by the literature review.</p><p><strong>Conclusion: </strong>Vitrectomy combined with repeated intravitreal injections of ceftazidime can enhance the treatment for brucellosis endophthalmitis and achieve a better visual prognosis.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"169-172"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Medical Insurance, Access to Care, and Outcomes for Patients with Uveal Melanoma in the United States.","authors":"Victoria A Marks, Basil K Williams, Michael S Leapman, Carol L Shields","doi":"10.1080/08820538.2024.2426479","DOIUrl":"10.1080/08820538.2024.2426479","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the association between insurance status and uveal melanoma (UM) care.</p><p><strong>Methods: </strong>We utilized the National Cancer Database to identify patients diagnosed with UM from 2004 to 2017. We examined the associations between patient sociodemographic characteristics, specifically insurance status, and UM care.</p><p><strong>Results: </strong>Of 7677 patients, 50% had private, 41% Medicare, 4% Medicaid, 3% other government, and 3% no insurance. Most initially received brachytherapy (66%), followed by enucleation/resection (19%) and other treatment (15%). Compared to private, Medicaid and no insurance were associated with higher odds of late-stage disease presentation (<i>p</i> < .05). Patients with Medicare, Medicaid, and no insurance had higher odds of enucleation/resection and lower odds of brachytherapy versus enucleation/resection (<i>p</i> < .05 for all). Medicaid and no insurance were associated with lower odds of other treatment versus enucleation/resection (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>Access barriers to UM care may exist based on insurance status and may be associated with later-stage presentation and more radical treatment.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"223-234"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Implanted Capsular Tension Ring on Postoperative Refractive Shift: A Systematic Review and Meta-Analysis.","authors":"Su Xu, Yuhang Zhang, Xintong Li, Wei Si, Gengqi Tian, Yifan Yang, Yizhuo Hu, Fengyan Zhang","doi":"10.1080/08820538.2024.2381770","DOIUrl":"10.1080/08820538.2024.2381770","url":null,"abstract":"<p><strong>Background: </strong>The capsular tension ring is a novel assistant tool for cataract surgery; however, controversy exists in its co-implantation. The potential for hyperopic or myopic shift resulting from the co-implantation of the capsular tension ring and intraocular lens remains unclear. This study aimed to determine the postoperative refractive prediction error and the direction of refractive shift in cataract patients who underwent capsular tension ring co-implantation.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis,searching electronic databases for studies of individuals diagnosed with cataracts receiving surgery with or without capsular tension ring implantation. Systematic searches were performed based on five databases: PubMed, Cochrane Library, Web of Science, Medline, and China National Knowledge Infrastructure. The primary outcome was the mean arithmetic refractive prediction error. Secondary outcomes were mean absolute refractive prediction error and the number of eyes within a certain refractive prediction error range. We applied a fixed-effectsmodel to pool effect sizes across trials using weighted mean differences (WMD) and risk ratios (RR) with their 95% confidence intervals (95% CI). Statistical heterogeneity scores were assessed with the I²statistic.</p><p><strong>Results: </strong>A total of 407 affected eyes were included in eight independent clinical studies. Meta-analysis suggested significant differences both in short-term (≤1 month) co-implantation (WMD = 0.16, <i>p</i> < .001, 95% CI: -0.13 ~ 0.19) and long-term (≥3 months) co-implantation between the capsular tension ring co-implantation group and the control group (WMD = 0.19, <i>p</i> < .001, 95% CI: 0.15 ~ 0.23). However, no significant difference was observed in the high myopia subgroup whether capsular tension ring co-implantation (WMD = 0.03, <i>p</i> = .083, 95% CI: -0.27 ~ 0.34). Heterogeneity was not found among the studies.</p><p><strong>Conclusion: </strong>Compared to simple intraocular lens implantation, capsular tension ring co-implantation is more susceptible to developing hyperopic shifts in non-myopic cataract patients, probably related to anterior chamber depth. It requires careful consideration by clinicians when determining the target diopter preoperatively. However, interpretation is limited, because there is a lack of studies available for analysis. There still needs to be additional studies to expand the evidence base.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"162-168"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravitreal Anti-Vascular Endothelial Growth Factor Agents in Patients with Neovascular Age-Related Macular Degeneration and Retinal Pigment Epithelial Tear: A Systematic Review and Meta-Analysis.","authors":"Eleftheria P Mavridou, Theodoros N Sergentanis, Ioannis Kapetanios, Panagiotis Theodossiadis, Irini Chatziralli","doi":"10.1080/08820538.2025.2486328","DOIUrl":"https://doi.org/10.1080/08820538.2025.2486328","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this systematic review and meta-analysis is to evaluate the outcomes of continuing versus discontinuing intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment at various follow-up time-points in neovascular age-related macular degeneration (nAMD) patients who developed retinal pigment epithelium (RPE) tears following anti-VEGF therapy.</p><p><strong>Methods: </strong>Relevant publications were identified through a systematic search in the PubMed and EMBASE databases. The standardized mean differences (SMD), with their 95% confidence intervals (95% CI), were estimated using random effects models (DerSimonian-Laird), as appropriate. Meta-regression analysis was also performed.</p><p><strong>Results: </strong>Thirty studies (including 479 eyes with RPE tear) were eligible for the systematic review and meta-analysis. These studies examined the outcomes in patients who continued anti-VEGF treatment post-tear and those who discontinued it, with comparisons made separately for different timepoints in each group. In patients who continued anti-VEGF treatment, the pooled best-corrected visual acuity (BCVA) showed no statistically significant difference compared to baseline at any time-point of the follow-up. The pooled central subfield thickness (CST) improved at 12 months, but did not reach a significant level (SMD -0.45; 95% CI: -0.99, 0.10, I² = 49.5%, <i>p</i> = .159). Long-term follow-up indicated a decrease in the presence of subretinal and intraretinal fluid. In patients who discontinued intravitreal anti-VEGF treatment, there was a non-significant improvement in BCVA within the first 3 months; however, BCVA fluctuated or worsened over time, and fibrosis development was observed.</p><p><strong>Conclusions: </strong>This systematic review and meta-analysis found that intravitreal injections of anti-VEGF do not significantly impact visual acuity in patients with RPE tears at various follow-up timepoints, but may provide anatomical improvement.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-10"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Second Intention Healing After Laser Ablation of Benign Eyelid Margin Tumors.","authors":"Gang Seok Jeon, In Hwan Hong, Tae Yeem Lee, Tae Geun Song, Jae Ryong Han","doi":"10.1080/08820538.2024.2435942","DOIUrl":"10.1080/08820538.2024.2435942","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to present the therapeutic outcomes of benign eyelid margin tumors treated with laser ablation, offering an alternative approach to traditional shaving biopsy.</p><p><strong>Methods: </strong>In all patients, tumors were eliminated through either laser ablation or shaving biopsy. Comparative analysis was conducted between two patient groups: the laser-assisted ablation group (Group 1) and the shaving excision surgery group (Group 2). A total of 66 patients with 67 benign eyelid margin tumors were retrospectively included in this study (2019-2023). Thity-four cases underwent laser ablation, and 33 cases were subjected to shaving excision biopsy. Postoperatively, histologic confirmation was obtained in 11 out of the 33 cases that underwent shaving excision.</p><p><strong>Results: </strong>In Group 1, no functional or cosmetic complications were observed. The wound margin was clear after laser-assisted ablation in all cases. In Group 2, there was one instance of eyelid notching, loss of cilia, and two pigmentations. No wound infections were reported. The average wound epithelialization duration was 3.3 weeks in Group 1, significantly faster than 4.2 weeks in Group 2 (<i>p</i> < .01). The average lesion size was 3.0 × 2.9 mm in Group 1, significantly smaller than 3.5 × 3.4 mm in Group 2 (<i>p</i> < .05). No recurrences were observed during the follow-up period.</p><p><strong>Conclusions: </strong>Laser ablation for small benign eyelid margin tumors may be a favorable alternative to shaving excision biopsy surgery. All patients were satisfied with the cosmetic result. There was no definitive postoperative or intraoperative complication during or after laser application.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"246-249"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Artificial Intelligence in the Diagnosis, Follow-Up and Prediction of Treatment of Ophthalmic Diseases.","authors":"Jinwei Yu, Fuqiang Li, Mingzhu Liu, Mengdi Zhang, Xiaoli Liu","doi":"10.1080/08820538.2024.2414353","DOIUrl":"10.1080/08820538.2024.2414353","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the application of artificial intelligence (AI) in ophthalmic diseases and its possible future directions.</p><p><strong>Methods: </strong>A retrospective review of the literature from PubMed, Web of Science, and Embase databases (2019-2024).</p><p><strong>Results: </strong>AI assists in cataract diagnosis, classification, preoperative lens calculation, surgical risk, postoperative vision prediction, and follow-up. For glaucoma, AI enhances early diagnosis, progression prediction, and surgical risk assessment. It detects diabetic retinopathy early and predicts treatment effects for diabetic macular edema. AI analyzes fundus images for age-related macular degeneration (AMD) diagnosis and risk prediction. Additionally, AI quantifies and grades vitreous opacities in uveitis. For retinopathy of prematurity, AI facilitates disease classification, predicting disease occurrence and severity. Recently, AI also predicts systemic diseases by analyzing fundus vascular changes.</p><p><strong>Conclusions: </strong>AI has been extensively used in diagnosing, following up, and predicting treatment outcomes for common blinding eye diseases. In addition, it also has a unique role in the prediction of systemic diseases.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"173-181"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}