Seminars in Ophthalmology最新文献

Long-Term Outcomes of Trabeculectomy with Collagen Matrix Implant as a Bevacizumab Depot.

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-08 DOI: 10.1080/08820538.2025.2488888

Faisal Thattaruthody, Natasha Gautam Seth, Parul Ichhpujani, Srishti Raj, Sushmita Kaushik, Surinder Singh Pandav

{"title":"Long-Term Outcomes of Trabeculectomy with Collagen Matrix Implant as a Bevacizumab Depot.","authors":"Faisal Thattaruthody, Natasha Gautam Seth, Parul Ichhpujani, Srishti Raj, Sushmita Kaushik, Surinder Singh Pandav","doi":"10.1080/08820538.2025.2488888","DOIUrl":"https://doi.org/10.1080/08820538.2025.2488888","url":null,"abstract":"Purpose: To report the long-term outcomes of trabeculectomy with collagen implant as bevacizumab depot in eyes with uncontrolled glaucoma.Method: In this retrospective non-comparative interventional study, medical records of patients (age ≥18 years) who underwent trabeculectomy with Ologen implant as bevacizumab depot for uncontrolled glaucoma with ≥ 2 years follow-up were reviewed. The underlying etiology, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and number of anti-glaucoma medications (AGM) were recorded at baseline. Postoperatively, BCVA, IOP, AGMs, complications, and re-surgery were noted on day 1, 1-week, 1-, 3-, 6- months, 1-, 2-, 3-, 4-, 5-years and at final follow-up after 24 months. The main outcomes measured were IOP, number of AGM, and cumulative probability of overall success after 2 years.Results: Forty-three eyes of 43 patients with a mean age of 54.79 ± 17.27 years were included. The mean follow-up was 62.9 ± 27.42 (24-108) months. The mean pre-operative IOP was 29.23 ± 10.09 mmHg with an average of 4.3 ± 1.2 AGM. The mean IOP and number of AGM were significantly reduced in all follow-up visits (p < .0001) following surgery. The complete success was 48.8% and 48.5% at 2-year and 5-year respectively. The cumulative probability of overall success was 95%, 85%, 80%, and 71% at 2-5-, 7-, and 9-years respectively. A total of 24 complications were noted in 15 eyes in early postoperative days, and all were managed conservatively. The failure was noticed in 6 (17.2%) eyes at 5-year study visits.Conclusion: The use of ologen implant as a drug depot for bevacizumab in trabeculectomy was safe and had a good long-term outcome.","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-7"},"PeriodicalIF":1.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Asymptomatic Fellow Eyes of Patients with Unilateral Epiphora by Lacrimal Irrigation Test and Dacryoscintigraphy.

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-03 DOI: 10.1080/08820538.2025.2486332

Nurşen Öncel Acır, Servet Çetinkaya

{"title":"Evaluation of Asymptomatic Fellow Eyes of Patients with Unilateral Epiphora by Lacrimal Irrigation Test and Dacryoscintigraphy.","authors":"Nurşen Öncel Acır, Servet Çetinkaya","doi":"10.1080/08820538.2025.2486332","DOIUrl":"https://doi.org/10.1080/08820538.2025.2486332","url":null,"abstract":"Objective: To evaluate the findings of dacryoscintigraphy (DSG) and lacrimal irrigation test (LIT) in asymptomatic fellow eyes of patients with unilateral epiphora, as well as the relationship between pathology of the lacrimal drainage system in symptomatic and asymptomatic eyes.Methods: This study included 396 patients who were followed up for symptomatic unilateral epiphora due to nasolacrimal stenosis or obstruction between January 2022 and June 2024. Initially, LIT was performed in both eyes of all patients (both symptomatic and asymptomatic eyes) using a 2 ml lacrimal cannula. In all cases, DSG was performed as part of the routine examination.Results: Among symptomatic eyes with unilateral epiphora, 72.2% (n = 286) had nasolacrimal duct obstruction, while 27.8% (n = 110) had nasolacrimal duct stenosis. When the asymptomatic fellow eyes of 396 eyes with unilateral epiphora were examined, DSG was normal in 247 eyes (62.4%) and abnormal in 149 eyes (37.6%). DSG abnormalities were post-sac delay in 137 eyes (34.6%) and pre-sac delay in 12 eyes (3.0%). When asymptomatic fellow eyes were analysed with LIT, 326 eyes (82.3%) had normal LIT, while only 70 eyes (17.7%) had an obstruction in LIT. Among the asymptomatic eyes, 239 (60.4%) had neither delay in DSG nor obstruction in LIT, while 87 (22.0%) had delay in DSG without obstruction in LIT. Only 8 (3.2%) of 247 eyes with no delay in the DSG had a blockage in the LIT. The concordance rate between LIT and DSG was 76.0% (301 eyes).Conclusion: The combined use of DSG and LIT in the evaluation of asymptomatic eyes of cases with unilateral epiphora is crucial to improve diagnostic accuracy and develop a more targeted treatment approach.","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-6"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lacrimal History - Part X: Doyens of Dacryology Series - Sir Percivall Pott (1714-1788) and His Lacrimal Treatise of 1758. 泪腺史 - 第十部分：泪腺学大师系列 - 珀西瓦尔-波特爵士（1714-1788 年）及其 1758 年的泪腺论文。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-10-20 DOI: 10.1080/08820538.2024.2417614

Mohammad Javed Ali

引用次数: 0

Changes in Eyelid Height Based on Intra-Operative Quantification of Levator Aponeurosis Advancement in Patients with Unilateral Ptosis. 根据术中对单侧上睑下垂患者提上睑肌前移的定量分析得出的眼睑高度变化。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-08-08 DOI: 10.1080/08820538.2024.2388625

Jose Miguel Ambat, Naoyuki Morishige, Yasuhiro Takahashi, Hirohiko Kakizaki

{"title":"Changes in Eyelid Height Based on Intra-Operative Quantification of Levator Aponeurosis Advancement in Patients with Unilateral Ptosis.","authors":"Jose Miguel Ambat, Naoyuki Morishige, Yasuhiro Takahashi, Hirohiko Kakizaki","doi":"10.1080/08820538.2024.2388625","DOIUrl":"10.1080/08820538.2024.2388625","url":null,"abstract":"Objective: To present marginal reflex distance (MRD-1) outcomes based on intra-operative quantification of levator aponeurosis advancement.Methods: Forty-eight patients with unilateral aponeurotic ptosis underwent anterior levator aponeurosis advancement. Distance of advancement intra-operatively was compared with MRD-1 outcomes at the immediate postoperative sitting, approximately 1 week, and 1 month period. Surgical success was defined as a symmetric MRD-1 or an MRD-1 within 1 millimeter of the contralateral eyelid.Results: Most MRD-1 exhibited the following trends: 1) initial decrease at about 1 week and increase at 1 month (n = 11), 2) initial increase at about 1 week with levelling at 1 month (n = 8), and 3) increasing through time (n = 7). Success rate significantly decreased through time (p = .0464). The change in proportion of successful and failed surgeries was insignificant. Surgical revision rate was 10.4%.Conclusion: Levator aponeurosis advancement distances do not correlate with MRD-1 outcomes linearly. MRD-1 exhibited stability over time with a satisfactory success rate at 1 month.","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"182-187"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Loss to Follow Up Among Glaucoma Patients: An IRIS® Registry (Intelligent Research in Sight) Retrospective Cohort Analysis. 青光眼患者失去随访机会：IRIS® Registry（Intelligent Research in Sight）回顾性队列分析。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-08-16 DOI: 10.1080/08820538.2024.2391826

Andrew M Williams, Lauren M Wasser, Julie Cassidy, Hsing-Hua Sylvia Lin

{"title":"Loss to Follow Up Among Glaucoma Patients: An IRIS® Registry (Intelligent Research in Sight) Retrospective Cohort Analysis.","authors":"Andrew M Williams, Lauren M Wasser, Julie Cassidy, Hsing-Hua Sylvia Lin","doi":"10.1080/08820538.2024.2391826","DOIUrl":"10.1080/08820538.2024.2391826","url":null,"abstract":"Purpose: To identify prevalence of and risk factors for loss to follow up (LTFU) among a national cohort of patients with primary open-angle glaucoma (POAG).Methods: This retrospective cohort study analyzed data from the IRIS® Registry (Intelligent Research in Sight) database from 2014 through 2019 to assess LTFU among adult patients with POAG. POAG patients with at least one clinical encounter in 2014 were included. LTFU was defined as exceeding one year without a clinical encounter during the study period.Results: Among 553,663 glaucoma patients, 277,019 (50%) became LTFU, of whom 184,548 (67%) never returned to care and 92,471 (33%) re-established follow-up after a lapse. Risk of LTFU was greatest among those younger than 60 years (RR = 1.38; 95% CI: 1.36-1.39) or older than 80 years (RR = 1.39; 95% CI: 1.38-1.40) compared to those in their 60s. Compared to White race, risk for LTFU was highest among Native Hawaiian/Pacific Islander (RR = 1.24; 95% CI: 1.17-1.31), Hispanic ethnicity (RR = 1.19; 95% CI: 1.18-1.20), and Black race (RR = 1.10; 95% CI: 1.09-1.11). Medicare insurance was associated with lower risk of LTFU (RR = 0.79; 95% CI: 0.78-0.79), whereas unknown/missing/no insurance was associated with greater risk (RR = 1.33; 95% CI: 1.32-1.34), compared to private insurance. Compared to mild-stage POAG, risk of LTFU was higher for moderate-stage (RR = 1.10; 95% CI: 1.08-1.13) and severe-stage disease (RR = 1.35; 95% CI: 1.32-1.38).Conclusion: We found a 50% prevalence of LTFU among POAG patients in the IRIS Registry over a 6-year study period, with greater risk among minority groups and those with more advanced disease.","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"188-195"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Trends and Hotspots of Big Data in Ophthalmology: A Bibliometric Analysis and Visualization. 眼科大数据的研究趋势与热点：文献计量分析与可视化。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-10-26 DOI: 10.1080/08820538.2024.2421478

Jiawei Chen, Xiang-Ling Yuan, Zhimin Liao, Wenxiang Zhu, Xiaoyu Zhou, Xuanchu Duan

{"title":"Research Trends and Hotspots of Big Data in Ophthalmology: A Bibliometric Analysis and Visualization.","authors":"Jiawei Chen, Xiang-Ling Yuan, Zhimin Liao, Wenxiang Zhu, Xiaoyu Zhou, Xuanchu Duan","doi":"10.1080/08820538.2024.2421478","DOIUrl":"10.1080/08820538.2024.2421478","url":null,"abstract":"Purpose: The burst of modern information has significantly promoted the development of global medicine into a new era of big data healthcare. Ophthalmology is one of the most prominent medical specialties driven by big data analytics. This study aimed to describe the development status and research hotspots of big data in ophthalmology.Methods: English articles and reviews related to big data in ophthalmology published from January 1, 1999, to April 30, 2024, were retrieved from the Web of Science Core Collection. The relevant information was analyzed and visualized using VOSviewer and CiteSpace software.Results: A total of 406 qualified documents were included in the analysis. The annual number of publications on big data in ophthalmology reached a rapidly increasing stage since 2019. The United States (n = 147) led in the number of publications, followed by India (n = 77) and China (n = 69). The L.V. Prasad Eye Institute in India was the most productive institution (n = 50), and Anthony Vipin Das was the most influential author with the most relevant literature (n = 45). The electronic medical records were the primary source of ophthalmic big data, and artificial intelligence served as the principal analytics tool. Diabetic retinopathy, glaucoma, and myopia are currently the main topics of interest in this field.Conclusions: The application of big data in ophthalmology has experienced rapid growth in recent years. Big data is expected to play an increasingly significant role in shaping the future of research and clinical practice in ophthalmology.","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"210-222"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142507450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lacrimal History - Part 27: Doyens of Dacryology Series - Geoffrey Edward Rose (1955-).

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2025-01-30 DOI: 10.1080/08820538.2025.2460364

Mohammad Javed Ali

引用次数: 0

Vitrectomy Combined with Repeated Intravitreal Injection of Ceftazidime for the Treatment of Brucellosis Endophthalmitis: A Case Report and Literature Review. 玻璃体切割联合重复玻璃体内注射头孢唑肟治疗布鲁氏菌病眼内炎：病例报告与文献综述。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-10-03 DOI: 10.1080/08820538.2024.2412050

Nan Guo, Yu-Jia Gui, Ying Chen

{"title":"Vitrectomy Combined with Repeated Intravitreal Injection of Ceftazidime for the Treatment of Brucellosis Endophthalmitis: A Case Report and Literature Review.","authors":"Nan Guo, Yu-Jia Gui, Ying Chen","doi":"10.1080/08820538.2024.2412050","DOIUrl":"10.1080/08820538.2024.2412050","url":null,"abstract":"Purpose: To present a treatment regimen for Brucellosis endophthalmitis that resulted in a good visual outcome. Additionally, we conducted a literature review on the treatment and visual prognosis of related cases.Case presentation: A 49-year-old woman with the chief complaint of decreased vision and redness in the right eye was initially diagnosed with noninfectious uveitis and prescribed high-dose steroids which led to transient improvement followed by a decline in vision. An infectious cause was suspected. Metagenomic next-generation sequencing of vitreous fluid and serological testing confirmed Brucella melitensis infection. The patient underwent vitrectomy combined with six intravitreal injections of ceftazidime in the right eye in addition to systemic antibiotic treatment. The intraocular inflammation was completely resolved, and the visual acuity recovered to 20/25, which is the best-documented recovery in Brucella endophthalmitis cases, as revealed by the literature review.Conclusion: Vitrectomy combined with repeated intravitreal injections of ceftazidime can enhance the treatment for brucellosis endophthalmitis and achieve a better visual prognosis.","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"169-172"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lacrimal History - Part 11: Doyens of Dacryology Series - Johann Gottfried Zinn (1727-1759) and his Anatomy Treatise of 1755. 泪腺史 - 第 11 部分：泪腺学大师系列 - 约翰-戈特弗里德-津恩（Johann Gottfried Zinn，1727-1759 年）及其 1755 年的解剖学论文。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-10-28 DOI: 10.1080/08820538.2024.2422224

Mohammad Javed Ali

引用次数: 0

Lacrimal History - Part 26: Doyens of Dacryology Series - George Brian Bartley (1955-). 泪腺史 - 第 26 部分：泪腺学大师系列 - 乔治-布莱恩-巴特利（George Brian Bartley，1955-）。

IF 1.9 4区医学

Seminars in Ophthalmology Pub Date : 2025-04-01 Epub Date: 2024-11-27 DOI: 10.1080/08820538.2024.2435695

Mohammad Javed Ali

引用次数: 0