Seminars in Ophthalmology最新文献

{"title":"Lacrimal History - Part 32: Doyens of Dacryology Series - Peter John Wormald (1959-).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2024.2445901","DOIUrl":"10.1080/08820538.2024.2445901","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"345-347"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syncope in the Ophthalmology Outpatient Department.","authors":"James Pietris, Stephen Bacchi, Arthas Flabouris, WengOnn Chan","doi":"10.1080/08820538.2025.2464003","DOIUrl":"10.1080/08820538.2025.2464003","url":null,"abstract":"<p><strong>Introduction: </strong>Syncope is a clinical symptom that occurs commonly in all medical facilities, including the ophthalmology outpatient department. A broad differential diagnosis exists for syncope, of which vasovagal syncope is the most common.</p><p><strong>Results: </strong>Efficient recognition and management of syncope in the ophthalmology department is essential to minimise its economic and time cost to patients, staff and the healthcare system.</p><p><strong>Conclusions: </strong>We propose a three-step approach to managing syncope for ophthalmology staff consisting of risk factor identification, preventative strategies and appropriate initial management to triage patients effectively and efficiently with minimal disruption to workflow in this inherently busy environment.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"389-392"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iran Thyroid Eye Disease (IrTED) Registry: Patient Characteristics and Clinical Presentation.","authors":"Shadi Akbarian, Nasser Karimi, Mansoureh Farhangniya, Hossein Ghahvehchian, Samira Chaibakhsh, Mohsen Bahmani Kashkouli","doi":"10.1080/08820538.2025.2463946","DOIUrl":"10.1080/08820538.2025.2463946","url":null,"abstract":"<p><strong>Purpose: </strong>This study explores the geographic distribution and ethnicity of Iranian patients with Thyroid Eye Disease (TED). It also analyzes semiology, the temporal relationship between thyroid dysfunction and TED, and concomitant diseases. An analysis of ocular visual and motility function in Iranian patients with TED at their initial presentation was also conducted.</p><p><strong>Methods: </strong>Data from the Iran TED Registry (IrTED) was extracted and analyzed to examine the demographics, clinical features, severity, and activity of TED. The study included patients who presented to the Rassoul Akram Hospital oculoplastic clinic in Tehran, Iran, between March 2020 and March 2023.</p><p><strong>Results: </strong>The database (https://orc.iums.ac.ir) included 685 patients (66.56% female), with congenital or acquired thyroid dysfunction/disease diagnosed with a mean age of 34.68 years (SD: 13.95, Range 0-78) and TED onset in the mean age of 37.79 years (SD: 14.06, Range: 2-78). Notably, 10.95% of patients developed TED before thyroid dysfunction, while 62.77% were diagnosed with thyroid dysfunction before the onset of TED. Elevated intraocular pressure (≥21 mmHg) in either eye was observed in 49 (7.15%) of participants, with 32 (4.67%) patients bilaterally involved. The distribution of registered patients by province of birth and ethnicity was also graphed. Semiology, coexisting health conditions, and visual and motility functions of patients were presented in a tabular format.</p><p><strong>Conclusion: </strong>The successful implementation of IrTED contributes to a better understanding of TED epidemiology and semiology within the Iranian population.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"412-418"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Efficacy and Safety of Preoperative Intravitreal Triamcinolone Acetonide Combined with Internal Limiting Membrane Peeling for the Treatment of Idiopathic Macular Epiretinal Membrane.","authors":"Jie Wang, Yuyan Liu, Yanhua Chu, Guoge Han, Quanhong Han","doi":"10.1080/08820538.2025.2463999","DOIUrl":"10.1080/08820538.2025.2463999","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the efficacy and safety of preoperative intravitreal triamcinolone acetonide (IVTA) combined with internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (IMEM).</p><p><strong>Methods: </strong>This was a retrospective study. Thirty-six phakic eyes of 35 patients were included in this study. IVTA was administered to 18 patients (18 eyes, Group IVTA) 7 days before vitrectomy, while the other 17 patients (18 eyes, Group no-IVTA) only underwent vitrectomy and ILM peeling. Patients were followed up for at least 6 months. Data on best-corrected visual acuity (BCVA), intraocular pressure (IOP), central macular thickness (CMT), inner retinal thickness (IRT), vascular parameters (measured by optical coherence tomography angiography, OCTA), mean macular sensitivity (MMS), 63% bivariate contour ellipse area (BCEA) and P1 (measured by macular integrity assessment, MAIA) were collected.</p><p><strong>Results: </strong>There were significant differences in BCVA and IRT between the IVTA group and the no-IVTA group at 6 months after surgery (<i>p</i> = .000 and <i>p</i> = .010). The CMT and MMS of the two groups significantly changed from the preoperative values; however, there were no differences between the 2 groups during the entire study period (<i>p</i> = .242 and <i>p</i> = .849). The changes in vascular parameters, including foveal avascular zone (FAZ) area and vessel densities of superficial and deep capillary plexus (SCP VD and DCP VD), in the two groups were not statistically significant. There were no statistically significant differences in 63% BCEA and P1 either.</p><p><strong>Conclusion: </strong>Macular morphology and macular integrity improved after vitrectomy combined with ILM peeling surgery. Compared with the no-IVTA group, preoperative intravitreal triamcinolone acetonide can improve best corrected visual acuity and accelerate the absorption of intraretinal fluid in terms of a significant reduction in IRT.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"426-432"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Survey of the Congenital Glaucoma Surgery Practice Patterns in the Indian Pediatric Glaucoma Society.","authors":"Anil K Mandal, Zayn Al-Timimi, Vijaya K Gothwal, Sushmita Kaushik, Sirisha Senthil, Viney Gupta, Shanta Balekudaru, Suneeta Dubey, Manju R Pillai","doi":"10.1080/08820538.2025.2457590","DOIUrl":"10.1080/08820538.2025.2457590","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the practice patterns among the Indian Pediatric Glaucoma Society (IPGS) members in the management of children with primary congenital glaucoma (PCG).</p><p><strong>Methods: </strong>An anonymous 74-question survey was administered online via Qualtrics (Qualtrics, Provo, Utah, USA) using a link sent by email to the 88 IPGS members. The questionnaire comprised five sections and was designed to gather information regarding respondent demographics and specialty training, clinic composition and volume, surgical practices and preferences, follow-up practices, and additional services. The survey was closed after 10 weeks. Data were analyzed using descriptive statistics and Chi-square tests. Statistical significance was set at <i>p</i> < .05.</p><p><strong>Results: </strong>The response rate was 82%. Of the 71 respondents, 49 (69%) reported possessing glaucoma fellowship training that included specialist training in pediatric glaucoma. By comparison, 8 respondents (11%) reported possessing pediatric ophthalmology fellowship training that included specialist training in pediatric glaucoma, and this difference was statistically significant (69% <i>vs</i>. 11%; χ² = 47.37; <i>p</i> < .0001). The majority of the respondents were in ophthalmic institution-based practice (83%) and were located in South India (58%). In cases of hazy cornea, the most common surgery (95%) performed was combined trabeculotomy-trabeculectomy while goniotomy was most preferred (49%) in cases of clear cornea. Approximately, one-half of the respondents (56%) preferred to operate on each eye in separate sessions, whereas 46% preferred to operate on both eyes in the same session. One-half of the respondents (51%) preferred to use mitomycin-C in primary surgery. The most common challenges in providing care were patient-related, including delayed presentation, high travel costs, and low socioeconomic status.</p><p><strong>Conclusions: </strong>Although a substantial consensus was found in most areas of management, a few areas, for example, use of MMC in primary surgery, showed diversity. The information gathered will enable glaucomatologists to compare their practices with those of their colleagues. In addition, this survey provides a baseline, allowing future trends in management to be determined.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"433-443"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT-Based Machine Learning Radiomics Analysis to Diagnose Dysthyroid Optic Neuropathy.","authors":"Lan Ma, Xue Jiang, Xuan Yang, Minghui Wang, Zhijia Hou, Ju Zhang, Dongmei Li","doi":"10.1080/08820538.2025.2463948","DOIUrl":"10.1080/08820538.2025.2463948","url":null,"abstract":"<p><strong>Purpose: </strong>To develop CT-based machine learning radiomics models used for the diagnosis of dysthyroid optic neuropathy (DON).</p><p><strong>Materials and methods: </strong>This is a retrospective study included 57 patients (114 orbits) diagnosed with thyroid-associated ophthalmopathy (TAO) at the Beijing Tongren Hospital between December 2019 and June 2023. CT scans, medical history, examination results, and clinical data of the participants were collected. DON was diagnosed based on clinical manifestations and examinations. The DON orbits and non-DON orbits were then divided into a training set and a test set at a ratio of approximately 7:3. The 3D slicer software was used to identify the volumes of interest (VOI). Radiomics features were extracted using the Pyradiomics and selected by t-test and least absolute shrinkage and selection operator (LASSO) regression algorithm with 10-fold cross-validation. Machine-learning models, including random forest (RF) model, support vector machine (SVM) model, and logistic regression (LR) model were built and validated by receiver operating characteristic (ROC) curves, area under the curves (AUC) and confusion matrix-related data. The net benefit of the models is shown by the decision curve analysis (DCA).</p><p><strong>Results: </strong>We extracted 107 features from the imaging data, representing various image information of the optic nerve and surrounding orbital tissues. Using the LASSO method, we identified the five most informative features. The AUC ranged from 0.77 to 0.80 in the training set and the AUC of the RF, SVM and LR models based on the features were 0.86, 0.80 and 0.83 in the test set, respectively. The DeLong test showed there was no significant difference between the three models (RF model vs SVM model: <i>p</i> = .92; RF model vs LR model: <i>p</i> = .94; SVM model vs LR model: <i>p</i> = .98) and the models showed optimal clinical efficacy in DCA.</p><p><strong>Conclusions: </strong>The CT-based machine learning radiomics analysis exhibited excellent ability to diagnose DON and may enhance diagnostic convenience.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"419-425"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penetrating Keratoplasty versus Deep Anterior Lamellar Keratoplasty for Keratoconus: A Systematic Review and Meta-Analysis of 27,018 Eyes.","authors":"Abdelaziz A Awad, Abdelrahman M Elettreby, Ahmed A Abo Elnaga, Mohamed A Alsaied, Menna M Aboelkhier, Maab Mohamed Saleh, Dalia Kamal Ewis, Mahmoud Ali, Fatma Mohammed, Mohamed A Aldemerdash, Hashem Abu Serhan","doi":"10.1080/08820538.2025.2457583","DOIUrl":"10.1080/08820538.2025.2457583","url":null,"abstract":"<p><strong>Purpose: </strong>Keratoconus is a bilateral asymmetrical degeneration in the cornea. It is associated with local thinning in the cornea leading to visual problems such as myopia and astigmatism. Several treatments, such as lenses and keratoplasty surgeries, were utilized to treat this condition. In this study, we aim to compare deep anterior lamellar keratoplasty (DALK) to penetrating keratoplasty (PK).</p><p><strong>Methods: </strong>We registered our study protocol on PROSPERO (CRD42024559427). Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched four electronic databases (PubMed, Scopus, Cochrane Library, and Web of Science) to identify eligible studies reported up to June 2024. Using STATA 17, we reported outcomes as risk ratios (RRs) or mean difference (MD) and confidence intervals (CIs). A P-value ≤.05 is considered as statistically significant.</p><p><strong>Results: </strong>The meta-analysis included a total of 47 studies with a total number of 27,018 eyes. There was no significant difference between PK and DALK in terms of best-corrected visual acuity (BCVA) at 1 year (Hedge's g: 0.03 with 95% CI [-0.13, 0.19], <i>p</i> = .71). PK was associated with a lower risk of graft failure than DALK (log RR: -0.41 with 95% CI [-0.74, -0.08], <i>p</i> = .01). PK was associated with a higher risk of graft rejection than DALK (log RR: 0.85 with 95% CI [0.35, 1.35], <i>p</i> < .001). There was no significant difference between PK and DALK in terms of corneal astigmatism at 1 year (Hedge's g: 0.03 with 95% CI [-0.24, 0.31], <i>p</i> = .82).</p><p><strong>Conclusion: </strong>The visual outcomes such as BCVA, astigmatism, and spherical equivalent refraction, of PK and DALK are comparable. However, PK was associated with a higher risk of complications and rejection episodes, but, a lower risk of graft failure.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"364-381"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications After Incisional/Excisional Minimally Invasive Glaucoma Surgery-An Update and Literature Review.","authors":"Aparna Rao, Manikanta Damagantla, Rashmi Krishnamurthy, Sirisha Senthil","doi":"10.1080/08820538.2025.2450687","DOIUrl":"10.1080/08820538.2025.2450687","url":null,"abstract":"<p><strong>Purpose: </strong>To discuss comprehensively the varied complications after stent-less incisional or excisional minimally invasive glaucoma surgery (MIGS).</p><p><strong>Method: </strong>A review of reported complications after stent-less MIGS procedures including gonioscopy-assisted transluminal trabeculotomy (GATT), bent needle goniectomy (BANG), Kahook-dual blade goniotomy, and microincisional trabeculectomy (MIT) published between 2014-2024, were analyzed and summarized.</p><p><strong>Results: </strong>Apart from hyphema, peripheral anterior synechiae, and intraocular pressure spikes, other vision-threatening complications like cyclodialysis, Descemet's detachment, corneal edema, iridodilalysis, vitreous loss or vitreous hemorrhage can also occur intra- or postoperatively after any incisional or excisional MIGS procedures.</p><p><strong>Conclusion: </strong>All possible complications are to be kept in mind during MIGS despite the procedures being minimally invasive. Adequate care should be taken during different stages of the surgery to avoid these complications.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"382-388"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 33: Doyens of Dacryology Series - Alan Angus McNab (1956-).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2450171","DOIUrl":"10.1080/08820538.2025.2450171","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"348-350"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 35: Doyens of Dacryology Series - Friedrich Paul Paulsen (1965-).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2459481","DOIUrl":"10.1080/08820538.2025.2459481","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"354-357"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}