Seminars in Ophthalmology最新文献

{"title":"Immediate Postoperative Difference of Eyelid Height Based on Intraoperative Measurement of Levator Aponeurosis Advancement in Patients with Unilateral Ptosis.","authors":"Jose Miguel Ambat, Steffani Krista Someda, Naoyuki Morishige, Yasuhiro Takahashi, Hirohiko Kakizaki","doi":"10.1080/08820538.2024.2416059","DOIUrl":"10.1080/08820538.2024.2416059","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the relationship between marginal reflex distance (MRD-1) outcomes and the distance of levator aponeurosis advancement.</p><p><strong>Methods: </strong>This retrospective observational study included patients with acquired unilateral aponeurotic ptosis, who underwent small-incision anterior levator advancement. The distance of levator advancement, and intra-operative MRD-1 in the sitting position, were analyzed to determine a correlation between the two.</p><p><strong>Results: </strong>Forty-eight patients were included. Results exhibited no direct relationship between advancement distance and MRD-1 measurements. Median and range of MRD-1 outcomes did not present a linear progression as the distance increased or decreased. A majority of advancement distances exhibited a median MRD-1 outcome of 4.00 mm (<i>n</i> = 3). Success criteria was met in 85.4% of surgeries performed.</p><p><strong>Conclusion: </strong>Due to varying postoperative MRD-1 outcomes, surgical results cannot be accurately predicted using predetermined advancement distances. Confirming the final MRD-1 in the sitting position with subsequent adjustment is still recommended.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"320-324"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142474219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitrectomy Combined with Internal Limiting Membrane Peeling for the Treatment of Hemorrhagic Retinal Arterial Macroaneurysm with \"Multilayered\" Hemorrhages.","authors":"Xueli Yang, Hongzhe Li, Haixia Guo, Han Han, Fengqi Zhou, Qihua Wang, Yuezhu Lu, Changjiao Zhang, Hua Yan","doi":"10.1080/08820538.2024.2426483","DOIUrl":"10.1080/08820538.2024.2426483","url":null,"abstract":"<p><strong>Aims: </strong>To report clinical outcomes of pars plana vitrectomy combined with internal limiting membrane (ILM) peeling in the treatment of \"multilayered\" hemorrhages caused by hemorrhagic retinal arterial microaneurysm (RAM) in three cases.</p><p><strong>Methods: </strong>Three patients with hemorrhagic RAM were reviewed. All patients underwent vitrectomy combined with ILM peeling. The diagnosis of RAM was confirmed by fluorescein angiography and optical coherence tomography after surgery.</p><p><strong>Results: </strong>All patients had yellowish-white prominent lesions with preretinal, intraretinal, and subretinal hemorrhaging with or without macular edema. Several months after the vitrectomy, the multilayered hemorrhages resolved without recurrent hemorrhage in the macular area. The exudative retinal detachment and macular edema associated with the RAM resolved, and eventually the RAM resolved, leaving behind white fibrous tissue. The visual acuity was improved in all patients.</p><p><strong>Conclusion: </strong>Vitrectomy combined with ILM peeling was an option for the treatment of RAM with \"multilayered\" hemorrhages. Postoperative visual acuity and anatomical structure were improved.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"267-274"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Pediatric Rhegmatogenous Retinal Detachment.","authors":"Theodore Bowe, Olufemi E Adams, Yoshihiro Yonekawa","doi":"10.1080/08820538.2024.2440725","DOIUrl":"10.1080/08820538.2024.2440725","url":null,"abstract":"<p><strong>Introduction and primary objective: </strong>Pediatric rhegmatogenous retinal detachment (RRD) presents unique challenges in diagnosis and management. A thorough evaluation of family, medical, and ocular history is helpful, as systemic and genetic conditions can predispose children to RRD. Trauma, high myopia, and history of prematurity are also common risk factors. Examining young children in the outpatient setting may have limitations, but the yield can be maximized by modifying examination techniques and utilizing imaging technologies. In this manscript, the considerations for diagnosis and management of pediatric rhegmatogenous retinal detachment are outlined.</p><p><strong>Conclusions: </strong>Primary scleral buckling is the treatment of choice for the vast majority of pediatric RRDs, as it offers a higher single surgery success rate in these young eyes with firmly adherent posterior hyaloid. Primary vitrectomy is not recommended due to this reason. Scleral buckling is the mainstay of pediatric RRD surgery, even in cases that may typically undergo vitrectomy in adults. Prophylactic treatment of the fellow eye may also be warranted in certain clinical scenarios. Understanding the unique challenges these patients face is important for early diagnosis, timely intervention, and tailored surgical strategies to optimize visual outcomes in this vulnerable patient population.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"283-287"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 30: Doyens of Dacryology Series - Bruno Fayet (1954-2022).","authors":"Francesco Quaranta-Leoni, Mohammad Javed Ali","doi":"10.1080/08820538.2024.2441049","DOIUrl":"10.1080/08820538.2024.2441049","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"261-263"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 31: Doyens of Dacryology Series - William Rocamora Katowitz (1966-).","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2443328","DOIUrl":"10.1080/08820538.2025.2443328","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"264-266"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 16: Doyens of Dacryology Series - Charles de Saint-Yves (1667-1736) and His Observations on Anchylops and Aegilops.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2496100","DOIUrl":"https://doi.org/10.1080/08820538.2025.2496100","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-4"},"PeriodicalIF":1.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence of Myopia and Its Association with Sleep Duration, Physical Activity, and Eye Exercises.","authors":"Juan Cao, Xiaolian Xie, Jing Li, Ling Zhang, Qi Chen, Juan Ma, Haiping Zhao, Jiangping Li, Leina Jia","doi":"10.1080/08820538.2025.2492256","DOIUrl":"https://doi.org/10.1080/08820538.2025.2492256","url":null,"abstract":"<p><strong>Purpose: </strong>Myopia is the most common visual impairment among Chinese children and adolescents. The purpose of this study is to explore key interventions for myopia prevalence, especially for early-onset myopia.</p><p><strong>Methods: </strong>Univariate and multivariate analyses were conducted to evaluate potential associations between risk factor exposure and myopia. Lasso regression was performed to prioritize the risk features, and the selected leading influencing factors were used to establish the assembled simulation model. Finally, the rms package of R was used to construct a nomogram forecasting model to predict the risk of myopia.</p><p><strong>Results: </strong>The prevalence of myopia among children and adolescents in Ningxia has shown a rapid upward trend in the past 25 years, from 50.3% in 1995 to 61.4% in 2019, with a growth rate of 10%. Children and adolescents with high grades had a high risk of myopia, which was 3.783 times higher in college school students than that of primary school students. Getting enough sleep time during school days per day (OR = 0.722, 95% CI: 0.620-0.840), be active in physical activity (OR = 0.823, 95% CI: 0.709-0.953), and do eye exercises (OR = 0.725, 95% CI: 0.570-0.919) were the top three protective factors. The AUCs of integrated simulation model for myopia was 0.707.</p><p><strong>Conclusions: </strong>The prevalence of myopia among children and adolescents were high in Ningxia Hui Autonomous Region of Northwest China, and the findings illustrate that reaching the recommended sleep time during school days, being active in physical exercise, and doing eye exercises among different ages are the leading three protective factors for myopia. Such data are critical and valuable for public health agencies to formulate intervention strategies for preventing high myopia and subsequent myopic maculopathy, cataract, retinal detachment, and glaucoma, including promotion of eye exercise, physical activity, enough sleep duration, and health education.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-8"},"PeriodicalIF":1.9,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetics of Retinoblastoma - An Update.","authors":"Adwaita Nag, Vikas Khetan","doi":"10.1080/08820538.2025.2492287","DOIUrl":"https://doi.org/10.1080/08820538.2025.2492287","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this review article is to provide an exhaustive overview of the genetic and epigenetic changes involved in retinoblastoma (RB) tumorigenesis along with their real-world applications.</p><p><strong>Methods: </strong>We searched the Pubmed database using keywords: retinoblastoma, genetics, epigenetics, oncogenes, tumor suppressor genes and target genes.</p><p><strong>Results: </strong>RB oncogenesis is triggered by biallelic RB1 gene mutation but progression involves additional genetic and epigenetic events. Commonly seen genetic mutations include nonsense, small insertions/deletions and splice mutations. Additional changes include copy number alterations, single nucleotide polymorphisms and epigenetic alterations (dysregulation of microRNAs, differential methylations). These pathways have led to the identification of several potential target genes that can play a role in future in precision therapy.</p><p><strong>Conclusions: </strong>Genetic testing, counseling and risk stratification are integral to the management of RB. The latest genetic advancements herald the dawn of a new era with potential therapeutic approaches to RB and improved treatment outcomes.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-9"},"PeriodicalIF":1.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging Insights in Thyroid Eye Disease Research from 2010 to 2022: Trends, Hot Spots, and Research Situation.","authors":"Yu-Xuan Wan, Guo-Qing Li, Sai-Li Duan, Shi Chang","doi":"10.1080/08820538.2025.2490669","DOIUrl":"https://doi.org/10.1080/08820538.2025.2490669","url":null,"abstract":"<p><strong>Purpose: </strong>Thyroid eye disease, the most frequent extra-thyroid manifestation of Graves' disease, has puzzled physicians and scientists and could potentially make patients sight-threatened. This study aimed to aid researchers and readers in this field to improve their understanding of thyroid eye disease research trends and provide ideas for future research from unique perspectives.</p><p><strong>Methods: </strong>The top 100 most-cited papers on Graves' ophthalmopathy from January 1, 2010, to December 31, 2022, were retrieved from the Web of Science Core Collection database. Two authors defined and analyzed these data independently via CiteSpace, Vosviewer, and Tableau.</p><p><strong>Results: </strong>A total of 1861 publications linked with Graves' ophthalmopathy research were identified. All of these 100 top-cited papers were published between 2010 and 2022, and the United States of America (USA), Italy, Germany, England, Netherlands, and China made significant contributions to Graves' ophthalmopathy research. The journal with the highest number of published papers is the Journal of Clinical Endocrinology & Metabolism (<i>n</i> = 22). The USA was the most productive country in this topic (<i>n</i> = 29). The Johannes Gutenberg University of Mainz had the largest number of publications (<i>n</i> = 8) and citations (<i>n</i> = 1610). The most cited article was 'MECHANISMS OF DISEASE Graves' Ophthalmopathy'. The clustered network and timeline of keywords showed the prevalence, diagnosis, and treatment of thyroid eye disease, which were the research core themes during the past 12 years.</p><p><strong>Conclusions: </strong>This study provided insights into the most influential studies related to thyroid eye disease via analyzing the top 100 most-cited papers in thyroid eye disease research.</p>","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-13"},"PeriodicalIF":1.9,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacrimal History - Part 14: Doyens of Dacryology Series - Georg Ernst Stahl (1659-1734) and His Lacrimal Propempticon of 1702.","authors":"Mohammad Javed Ali","doi":"10.1080/08820538.2025.2492431","DOIUrl":"https://doi.org/10.1080/08820538.2025.2492431","url":null,"abstract":"","PeriodicalId":21702,"journal":{"name":"Seminars in Ophthalmology","volume":" ","pages":"1-3"},"PeriodicalIF":1.9,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}