发布求助
文献互助 智能选刊 最新文献

Seminars in nuclear medicine最新文献

筛选
英文 中文
Letter from the Editors. 编辑来信
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2025-01-01 Epub Date: 2024-11-26 DOI: 10.1053/j.semnuclmed.2024.11.003
Kirsten Bouchelouche, M Michael Sathekge
{"title":"Letter from the Editors.","authors":"Kirsten Bouchelouche, M Michael Sathekge","doi":"10.1053/j.semnuclmed.2024.11.003","DOIUrl":"10.1053/j.semnuclmed.2024.11.003","url":null,"abstract":"","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":"1-2"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total-Body PET/CT: Pros and Cons. 全身 PET/CT：利与弊
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.1053/j.semnuclmed.2024.07.003
Rodney J Hicks, Robert E Ware, Jason Callahan
{"title":"Total-Body PET/CT: Pros and Cons.","authors":"Rodney J Hicks, Robert E Ware, Jason Callahan","doi":"10.1053/j.semnuclmed.2024.07.003","DOIUrl":"10.1053/j.semnuclmed.2024.07.003","url":null,"abstract":"<p><p>PET/CT devices with an axial field-of-view (FOV) of 1 m allow simultaneous imaging from the head to the upper thighs, the typical axial extent of many \"whole-body\" oncological studies acquired by moving a patient sequentially through a conventional FOV device, or rapid total-body imaging using the same approach. Increasing the FOV to around 2 m provides true simultaneous total-body imaging. Either approach dramatically increases the sensitivity for detection of annihilation events arising within the body. For the purposes of this review, both configurations are considered to represent \"total-body\" PET/CT devices because they share both advantages and disadvantages. These pros and cons are discussed in the context of both clinical and research applications from a patient and institutional perspective.</p>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":"11-20"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long Axial Field-of-View PET/CT: New Opportunities for Pediatric Imaging. 长轴视野 PET/CT：儿科成像的新机遇。
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2025-01-01 Epub Date: 2024-11-13 DOI: 10.1053/j.semnuclmed.2024.10.007
André Henrique Dias, Kim Francis Andersen, Marie Øbro Fosbøl, Lars Christian Gormsen, Flemming Littrup Andersen, Ole Lajord Munk
{"title":"Long Axial Field-of-View PET/CT: New Opportunities for Pediatric Imaging.","authors":"André Henrique Dias, Kim Francis Andersen, Marie Øbro Fosbøl, Lars Christian Gormsen, Flemming Littrup Andersen, Ole Lajord Munk","doi":"10.1053/j.semnuclmed.2024.10.007","DOIUrl":"10.1053/j.semnuclmed.2024.10.007","url":null,"abstract":"<p><p>The combined use of Positron Emission Tomography (PET) and Computed Tomography (CT) has become increasingly vital for diagnosing and managing oncological and infectious diseases in pediatric patients. The introduction of long axial field-of-view (LAFOV) PET/CT scanners, also known as \"Total Body PET/CT,\" marks a significant advancement in nuclear medicine. This new technology enables faster pediatric imaging with substantially reduced radiation exposure and essentially eliminates the need for sedation, addressing previous critical concerns in pediatric imaging. This review will explore the applications and challenges of LAFOV PET/CT in pediatric imaging, highlight the benefits observed at two Danish hospitals, and evaluate its potential to transform the management of pediatric patients.</p>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":"76-85"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Body PET/CT: A Role in Musculoskeletal Diseases. 全身 PET/CT：在肌肉骨骼疾病中的作用
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2025-01-01 Epub Date: 2024-06-29 DOI: 10.1053/j.semnuclmed.2024.05.009
Sanaz Katal, Parth Patel, Jonathan Lee, Kim Taubman, Ali Gholamrezanezhad
{"title":"Total Body PET/CT: A Role in Musculoskeletal Diseases.","authors":"Sanaz Katal, Parth Patel, Jonathan Lee, Kim Taubman, Ali Gholamrezanezhad","doi":"10.1053/j.semnuclmed.2024.05.009","DOIUrl":"10.1053/j.semnuclmed.2024.05.009","url":null,"abstract":"<p><p>Recent advancements in PET technology have culminated in the development of total-body PET (TB-PET) systems, which overcome many limitations of traditional scanners. These TB-PET scanners, while still becoming widely available, represent the forefront of clinical imaging across numerous medical institutions worldwide. Early clinical applications have demonstrated their enhanced image quality, precise lesion quantification, and overall superior performance relative to conventional scanners. The capabilities of TB-PET technology, including extended scan range, ultrahigh sensitivity, exceptional temporal resolution, and dynamic imaging, offer significant potential to tackle unresolved clinical challenges in medical imaging. In this discussion, we aim to explore the emerging applications, opportunities, and future perspectives of TB-PET/CT in musculoskeletal disorders (MSDs). Clinical applications for both oncologic and non-oncologic musculoskeletal diseases are discussed, including inflammatory arthritis, infections, osteoarthritis, osteoporosis, and skeletal muscle disorders. From the ability to visualize small musculoskeletal structures and the entire axial and appendicular skeleton, TB-PET shows significant potential in the diagnosis and management of MSD conditions as it becomes more widely available.</p>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":"86-97"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Body Positron Emission Tomography/Computed Tomography: Current Status in Oncology. 全身正电子发射断层扫描/计算机断层扫描：肿瘤学现状》。
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2025-01-01 Epub Date: 2024-11-07 DOI: 10.1053/j.semnuclmed.2024.10.006
Cristina Nanni, Andrea Farolfi, Paolo Castellucci, Stefano Fanti
{"title":"Total Body Positron Emission Tomography/Computed Tomography: Current Status in Oncology.","authors":"Cristina Nanni, Andrea Farolfi, Paolo Castellucci, Stefano Fanti","doi":"10.1053/j.semnuclmed.2024.10.006","DOIUrl":"10.1053/j.semnuclmed.2024.10.006","url":null,"abstract":"<p><p>Positron Emission Tomography (PET) is a crucial imaging modality in oncology, providing functional insights by detecting metabolic activity in tissues. Total-body (TB) PET and large field-of-view PET have emerged as advanced techniques, offering whole-body imaging in a single acquisition. TB PET enables simultaneous imaging from head to toe, providing comprehensive information on tumor distribution, metastasis, and treatment response. This is particularly valuable in oncology, where metastatic spread often requires evaluation of multiple body areas. By covering the entire body, TB PET improves diagnostic accuracy, reduces scan time, and increases patient comfort. Furthermore, these new tomographs offer a marked increase in sensitivity, thanks to their ability to capture a larger volume of data simultaneously. This heightened sensitivity enables the detection of smaller lesions and more subtle metabolic changes, improving diagnostic accuracy in the early stages of cancer or in the evaluation of minimal residual disease. Moreover, the increased sensitivity allows for lower radiotracer doses without compromising image quality, reducing patient exposure to radiation or very quick acquisitions. Another significant advantage is the possibility of dynamic acquisitions, which allow for continuous monitoring of tracer kinetics over time. This provides critical information about tissue perfusion, metabolism, and receptor binding in real time. Dynamic imaging is particularly useful for assessing treatment response in oncology, as it enables the evaluation of tumor behavior over a period rather than a single static snapshot, offering insights into tumor aggressiveness and potential therapeutic targets. This review is focused on the current applications of TB and large field-of-view PET scanners in oncology.</p>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":"31-40"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiomics and Artificial Intelligence Landscape for [18F]FDG PET/CT in Multiple Myeloma. 多发性骨髓瘤[18F]FDG PET/CT 的放射组学和人工智能前景。
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2024-12-13 DOI: 10.1053/j.semnuclmed.2024.11.005
Christos Sachpekidis, Hartmut Goldschmidt, Lars Edenbrandt, Antonia Dimitrakopoulou-Strauss
{"title":"Radiomics and Artificial Intelligence Landscape for [<sup>18</sup>F]FDG PET/CT in Multiple Myeloma.","authors":"Christos Sachpekidis, Hartmut Goldschmidt, Lars Edenbrandt, Antonia Dimitrakopoulou-Strauss","doi":"10.1053/j.semnuclmed.2024.11.005","DOIUrl":"https://doi.org/10.1053/j.semnuclmed.2024.11.005","url":null,"abstract":"<p><p>[<sup>18</sup>F]FDG PET/CT is a powerful imaging modality of high performance in multiple myeloma (MM) and is considered the appropriate method for assessing treatment response in this disease. On the other hand, due to the heterogeneous and sometimes complex patterns of bone marrow infiltration in MM, the interpretation of PET/CT can be particularly challenging, hampering interobserver reproducibility and limiting the diagnostic and prognostic ability of the modality. Although many approaches have been developed to address the issue of standardization, none can yet be considered a standard method for interpretation or objective quantification of PET/CT. Therefore, advanced diagnostic quantification approaches are needed to support and potentially guide the management of MM. In recent years, radiomics has emerged as an innovative method for high-throughput mining of image-derived features for clinical decision making, which may be particularly helpful in oncology. In addition, machine learning and deep learning, both subfields of artificial intelligence (AI) closely related to the radiomics process, have been increasingly applied to automated image analysis, offering new possibilities for a standardized evaluation of imaging modalities such as CT, PET/CT and MRI in oncology. In line with this, the initial but steadily growing literature on the application of radiomics and AI-based methods in the field of [<sup>18</sup>F]FDG PET/CT in MM has already yielded encouraging results, offering a potentially reliable tool towards optimization and standardization of interpretation in this disease. The main results of these studies are presented in this review.</p>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence and Workforce Diversity in Nuclear Medicine. 核医学中的人工智能和劳动力多样性。
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2024-11-19 DOI: 10.1053/j.semnuclmed.2024.10.005
K Elizabeth Hawk, Geoffrey M Currie
{"title":"Artificial Intelligence and Workforce Diversity in Nuclear Medicine.","authors":"K Elizabeth Hawk, Geoffrey M Currie","doi":"10.1053/j.semnuclmed.2024.10.005","DOIUrl":"https://doi.org/10.1053/j.semnuclmed.2024.10.005","url":null,"abstract":"<p><p>Artificial intelligence (AI) has rapidly reshaped the global practice of nuclear medicine. Through this shift, the integration of AI into nuclear medicine education, clinical practice, and research has a significant impact on workforce diversity. While AI in nuclear medicine has the potential to be a powerful tool to improve clinical, research and educational practice, and to enhance patient care, careful examination of the impact of each AI tool needs to be undertaken with respect to the impact on, among other factors, diversity in the nuclear medicine workforce. Some AI tools can be used to specifically drive inclusivity and diversity of the workforce by supporting women and underrepresented minorities. Other tools, however, have the potential to negatively impact minority groups, leading to a widening of the diversity gap. This manuscript explores how various AI solutions have the potential to both negatively and positively affect diversity in the nuclear medicine workforce.</p>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter From the Editors 编辑来信
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2024-11-01 DOI: 10.1053/j.semnuclmed.2024.10.010
M. Michael Sathekge MD, PhD, Kirsten Bouchelouche MD, DMSc
{"title":"Letter From the Editors","authors":"M. Michael Sathekge MD, PhD,&nbsp;Kirsten Bouchelouche MD, DMSc","doi":"10.1053/j.semnuclmed.2024.10.010","DOIUrl":"10.1053/j.semnuclmed.2024.10.010","url":null,"abstract":"","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":"54 6","pages":"Pages 775-777"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copper-64 Based PET-Radiopharmaceuticals: Ways to Clinical Translational 基于铜-64 的 PET 放射药物：临床转化的途径
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2024-11-01 DOI: 10.1053/j.semnuclmed.2024.10.002
Nan Yang PhD , Xiao-yi Guo PhD , Jin Ding PhD, Feng Wang PhD, Te-li Liu PhD, Hua Zhu MD, PhD , Zhi Yang MD, PhD
{"title":"Copper-64 Based PET-Radiopharmaceuticals: Ways to Clinical Translational","authors":"Nan Yang PhD ,&nbsp;Xiao-yi Guo PhD ,&nbsp;Jin Ding PhD,&nbsp;Feng Wang PhD,&nbsp;Te-li Liu PhD,&nbsp;Hua Zhu MD, PhD ,&nbsp;Zhi Yang MD, PhD","doi":"10.1053/j.semnuclmed.2024.10.002","DOIUrl":"10.1053/j.semnuclmed.2024.10.002","url":null,"abstract":"<div><div>Positron emission tomography (PET) as an advanced noninvasive imaging technique, provides unprecedented insights into the study of physiological and biochemical processes in vivo. Copper-64 (<sup>64</sup>Cu) has a ideal half-life of 12.7 hours, with β+ and β-dual decay modes and abundant coordination chemistry, enabling the development of a wide variety of radiopharmaceuticals for PET imaging and radionuclide therapy.This review provides a comprehensive overview of the latest advances in Copper-64 (<sup>64</sup>Cu)-based PET radionuclides, covering their production, radiolabeling strategies, and clinical applications. It highlights the role of <sup>64</sup>Cu-PET in enhancing diagnostic accuracy and therapeutic outcomes across various tumor types. Additionally, future research directions and the evolving clinical applications of <sup>64</sup>Cu-based radiopharmaceuticals are discussed, offering insights into their potential impact on clinical practice.</div></div>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":"54 6","pages":"Pages 792-800"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging TSPO-PET Radiotracers for Imaging Neuroinflammation: A Critical Analysis 用于神经炎症成像的新兴 TSPO-PET 放射性标记物：批判性分析。
IF 4.6 2区 医学
Seminars in nuclear medicine Pub Date : 2024-11-01 DOI: 10.1053/j.semnuclmed.2024.09.007
Grace A. Cumbers MBMSc , Edward D. Harvey-Latham BSc(Hons) , Michael Kassiou PhD , Eryn L. Werry PhD , Jonathan J. Danon PhD
{"title":"Emerging TSPO-PET Radiotracers for Imaging Neuroinflammation: A Critical Analysis","authors":"Grace A. Cumbers MBMSc ,&nbsp;Edward D. Harvey-Latham BSc(Hons) ,&nbsp;Michael Kassiou PhD ,&nbsp;Eryn L. Werry PhD ,&nbsp;Jonathan J. Danon PhD","doi":"10.1053/j.semnuclmed.2024.09.007","DOIUrl":"10.1053/j.semnuclmed.2024.09.007","url":null,"abstract":"<div><div>The translocator protein (TSPO) is a biomarker for imaging neuroinflammation via Positron Emission Tomography (PET) across a broad range of CNS conditions. Most clinically used PET ligands targeting TSPO have limitations, including high lipophilicity and off-target binding or poor binding to a mutated TSPO isoform present in up to 30% of the population. Research efforts over the past decade have focused on development of improved TSPO PET radiotracers that overcome these limitations. This review provides a critical analysis of the development and validation of these so-called “third-generation” radiotracers in clinical and preclinical settings. We also offer our perspective on the future directions of TSPO PET imaging, including recommendations for overcoming current challenges and capitalizing on emerging opportunities in molecular imaging for neuroinflammatory diseases.</div></div>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":"54 6","pages":"Pages 856-874"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信