Emil Novruzov, Eduards Mamlins, Yuriko Mori, Jens Cardinale, Frederik L. Giesel
{"title":"The Clinical Impact of FAPI PET Imaging: HCC, CCC, CUP & Peritoneal Carcinoma","authors":"Emil Novruzov, Eduards Mamlins, Yuriko Mori, Jens Cardinale, Frederik L. Giesel","doi":"10.1053/j.semnuclmed.2025.07.001","DOIUrl":null,"url":null,"abstract":"<div><div>In recent years, FAP-targeted imaging has emerged as a highly-promising modality as a pan-cancer agent. Until now, several studies and review articles have focused on efficacy of FAPI imaging in epithelial malignancies with a high global incidence and prevalence such as lung cancer or GI-tumors. This work sought to shed light on diagnostic performance and clinical impact of FAPI imaging in rather low-incidence tumor-entities, which are nevertheless characterized by a poor outcome.</div></div>","PeriodicalId":21643,"journal":{"name":"Seminars in nuclear medicine","volume":"55 5","pages":"Pages 724-733"},"PeriodicalIF":5.9000,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in nuclear medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S000129982500090X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, FAP-targeted imaging has emerged as a highly-promising modality as a pan-cancer agent. Until now, several studies and review articles have focused on efficacy of FAPI imaging in epithelial malignancies with a high global incidence and prevalence such as lung cancer or GI-tumors. This work sought to shed light on diagnostic performance and clinical impact of FAPI imaging in rather low-incidence tumor-entities, which are nevertheless characterized by a poor outcome.
期刊介绍:
Seminars in Nuclear Medicine is the leading review journal in nuclear medicine. Each issue brings you expert reviews and commentary on a single topic as selected by the Editors. The journal contains extensive coverage of the field of nuclear medicine, including PET, SPECT, and other molecular imaging studies, and related imaging studies. Full-color illustrations are used throughout to highlight important findings. Seminars is included in PubMed/Medline, Thomson/ISI, and other major scientific indexes.