Sexually Transmitted Infections最新文献

{"title":"Preferences for online or in-person STI testing vary by where a person lives and their cultural background: a survey of young Australians.","authors":"Ethan T Cardwell, Olivia Walsh, Shanton Chang, Jacqueline Coombe, Christopher K Fairley, Jane S Hocking, Fabian Yuh Shiong Kong, Teralynn Ludwick","doi":"10.1136/sextrans-2024-056292","DOIUrl":"10.1136/sextrans-2024-056292","url":null,"abstract":"<p><strong>Objectives: </strong>The objectives are to explore the acceptability of online sexually transmitted infection (STI) testing services among young Australians (16-29 years) and how this may vary between sociodemographic populations.</p><p><strong>Methods: </strong>A cross-sectional, online survey (using both closed and open-ended questions) of Australians aged 16-29 years. Of 905 participants, 781 (86%) responded to the question on preference for online versus in-person STI testing and are included in this analysis. Logistic regression was used to identify sociodemographic factors associated with STI testing preferences (online vs in-person). Adjusted ORs (AOR) are reported for each sociodemographic factor. Content analysis was used to code open-ended responses explaining the reasons for the participant's testing preference.</p><p><strong>Results: </strong>Among the participants, 75% (588/781) preferred online testing over in-person testing. 677 (87%) provided reasons for their preference in an associated, open-ended question. Multivariable analysis found that the odds of preferring online services were significantly increased for those living in rural compared with metropolitan areas (AOR=1.7, 1.0-2.9). The odds of preferring online testing over in-person testing were significantly decreased for those of Asian descent (AOR=0.4, 0.2-0.6) and for those who reported having previously tested for an STI (0.6, 0.4-0.9). Convenience and privacy were key factors from the content analysis underlining preferences for online testing services but tended to be voiced by participants with certain sociodemographic characteristics (ie, men who have sex with men and older participants). Factors related to trust and convenience underscored preferences related to in-person testing.</p><p><strong>Conclusions: </strong>It is clear that there is considerable interest among young people in using online STI testing, but it may not be right for all individuals. Understanding what factors associated with online testing are valued by young users can help inform marketing strategies that highlight these value propositions in their messaging. Further research is needed to engage young people and develop a high-quality, usable online service.</p>","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":"168-173"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidrug-resistant urethritis caused by <i>Haemophilus parainfluenzae</i>: susceptibility pattern and fosfomycin as an alternative treatment.","authors":"Berta Isabel Fidalgo, Jordi Iglesies, David García, Andrea Vergara, Irene Fuertes de Vega, Laura Horvath, Yuliya Zboromyrska, Jordi Bosch, Ana González, José Riera-Monroig, Ignasi Roca, Marina Alguacil, Climent Casals-Pascual, Cristina Pitart, Josep Mallolas, José Luis Blanco, Mateu Espasa","doi":"10.1136/sextrans-2024-056142","DOIUrl":"10.1136/sextrans-2024-056142","url":null,"abstract":"","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":"201-202"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences and attitudes to sexual health services for young people: a national survey of people aged 13-24 years in Britain.","authors":"Harriet LeVoir, Shema Tariq, Jane Ashby","doi":"10.1136/sextrans-2024-056154","DOIUrl":"https://doi.org/10.1136/sextrans-2024-056154","url":null,"abstract":"","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":"101 3","pages":"209-210"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High burden of human papillomavirus and premalignant cervical lesions among women starting HIV treatment in KwaZulu-Natal, South Africa.","authors":"Nivashnee Naicker, Farzana Osman, Kunthi Naidoo, Nicola Bodley, Nokuthandwa Mbambo, Sibongile Madlala, Thobile Mhlongo, Nomfundo Mbatha, Andile Maphumulo, Pedzisai Munatsi, Precious Radebe, Lenine Liebenberg, Jienchi Dorward, Paul K Drain, Nigel Garrett","doi":"10.1136/sextrans-2024-056129","DOIUrl":"10.1136/sextrans-2024-056129","url":null,"abstract":"<p><strong>Objectives: </strong>Human papillomavirus (HPV) can cause cervical cancer, a leading cause of female cancer mortality in South Africa and worldwide. We assessed the burden of, and factors associated with, HPV infection using a molecular assay and cervical cytology among women living with HIV (WLHIV) in South Africa.</p><p><strong>Methods: </strong>In this cross-sectional analysis, WLHIV initiating antiretroviral therapy (ART) underwent cervical Xpert HPV testing and liquid-based cytology. The Xpert test detects 14 high-risk (hr) HPV types reported in a pooled qualitative result. We evaluated clinical and sociodemographic variables and proportions between women testing positive and negative for hr-HPV, compared cytology with hr-HPV results and assessed associations with HPV positivity.</p><p><strong>Results: </strong>We enrolled 260 WLHIV, median age 31.0 (IQR 26.0-38.0) years. Overall, 91.3% of women were never screened for cervical cancer previously and none received HPV vaccination. In total, 67.3% (175/260) of women tested positive for any hr-HPV type, of which HPV16 and HPV18/45 were detected in 17.3% (45/260) and 22.7% (59/260) of women, respectively, and 56.5% (147/260) tested positive for 11 other hr-types. Of 258 WLHIV, 33.3% (86/258) had abnormal cytology: high-grade squamous intraepithelial lesion (SIL) 7.8% (20/258), low-grade SIL 24.0% (62/258) and atypical squamous cells of undetermined significance 1.6% (4/258). Of these, 93.0% (80/86) tested positive for hr-HPV: 30.0% (24/80) for HPV16, 31.3% (25/80) for HPV18/45 and 92.5% (74/80) for other hr-HPV types. Having a CD4 count<200 cells/µL was associated with hr-HPV infection (adjusted prevalence ratio 2.24; 95% CI 1.69 to 2.99 (p<0.001)).</p><p><strong>Conclusions: </strong>hr-HPV infection and cervical abnormalities are common among WLHIV starting ART, especially those with low CD4 counts, highlighting that early HIV testing and treatment initiation must be prioritised together with cervical cancer screening. The diversity of hr-HPV types suggests a need for vaccines with expanded HPV type coverage in this setting.</p>","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":"187-190"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11999783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High frequency of anal high-risk human papillomavirus and abnormal cytology in men living with HIV in Chile.","authors":"Tomás Reyes-Barros, Patricia García-Cañete, Pablo Zoroquiain-Vélez, Javier Hernández-Pizarro, Óscar Corsi-Sotelo, María Elena Ceballos-Valdivielso","doi":"10.1136/sextrans-2024-056305","DOIUrl":"10.1136/sextrans-2024-056305","url":null,"abstract":"","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":"205-206"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of asymptomatic chlamydia and gonorrhoea drives antibiotic consumption in PrEP cohorts.","authors":"Thibaut Vanbaelen, Sheeba Santhini Manoharan-Basil, Chris Kenyon","doi":"10.1136/sextrans-2024-056381","DOIUrl":"10.1136/sextrans-2024-056381","url":null,"abstract":"","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":"207-208"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High prevalence of STIs among men engaged in transactional sex and alcohol use in western Kenya: important implications for STI prevention interventions.","authors":"Sue Napierala, Elizabeth F Bair, Ouma Dan Omollo, Teniola I Egbe, Julius Oduor Wesonga, Anisha Rajaratnam, Connie Celum, Harsha Thirumurthy, Kawango Agot","doi":"10.1136/sextrans-2024-056266","DOIUrl":"10.1136/sextrans-2024-056266","url":null,"abstract":"<p><strong>Objectives: </strong>Better data on aetiological prevalence of sexually transmitted infections (STIs) among African men could greatly strengthen STI prevention efforts and convey benefits to women as well. In an ongoing study among men in Kenya, we analysed baseline STI prevalence and individual characteristics associated with STI.</p><p><strong>Methods: </strong>In Siaya County, Kenya, we recruited men aged 18-39 years who self-reported engagement in transactional sex and alcohol use. We administered a baseline questionnaire to participants and conducted testing for HIV, herpes simplex virus type 2 (HSV-2), <i>Chlamydia trachomatis</i> (CT) and <i>Neisseria gonorrhoeae</i> (NG) infection. Characteristics associated with bacterial STIs were analysed using logistic regression and we estimated the positive and negative predictive values (PPV/NPV) of syndromic management of these infections.</p><p><strong>Results: </strong>We enrolled 1500 participants from July 2022 to March 2023. Participant mean age was 27.9 years, 62.2% were married/cohabitating and 53.5% were heavy alcohol users (Alcohol Use Disorders Identification Test-Consumption≥4). Participants reported a mean of 4.2 sexual partners and 3.5 transactional sex partners in the past 3 months. HIV prevalence was 9.5%, HSV-2 was 38.7%, CT was 14.3% and NG was 2.5%. Combined CT and/or NG infection was detected in 16.1% of participants.Compared with participants uninfected, those testing positive for CT and/or NG were younger (p=0.001), had more sexual partners (p=0.027) and transactional sex partners (p=0.039), were less likely to have used a condom at last sex (p=0.015) and were more likely to self-report having an STI besides HIV in the past 12 months (p=0.002). The PPV and NPV for currently experiencing CT and/or NG symptoms were 33.3% and 84.4%, respectively.</p><p><strong>Conclusions: </strong>Among Kenyan men engaged in transactional sex and alcohol use, STI prevalence was high. These data fill an important gap about STI prevalence and risk factors in African men highlighting the risk of ongoing transmission and the need for targeted prevention programmes and expanded access to testing and treatment.</p>","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":"183-186"},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11999786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular presentation of primary syphilis in a man with HIV.","authors":"Riccardo Schiavoni, Laura Labate, Matteo Cerchiaro, Raffaella Rosa, Massimo Niccolo, Laura Mezzogori, Lucia Taramasso, Matteo Bassetti, Antonio Di Biagio","doi":"10.1136/sextrans-2024-056347","DOIUrl":"https://doi.org/10.1136/sextrans-2024-056347","url":null,"abstract":"<p><p>The incidence of syphilis is rising, particularly among men who have sex with men. Ocular involvement, often manifesting as bilateral uveitis, typically occurs in later stages and is more severe and difficult to recognise in individuals living with HIV. We describe the case of a man with HIV infection who presented to our outpatient clinic with vision loss and a cutaneous maculopapular rash.</p>","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing persistent and recurrent candidiasis due to fluconazole-resistant <i>Candida albicans</i> and non-<i>Candida albicans</i> yeasts.","authors":"Janet D Wilson","doi":"10.1136/sextrans-2025-056532","DOIUrl":"https://doi.org/10.1136/sextrans-2025-056532","url":null,"abstract":"","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does frequent chlamydia screening lead to higher bacterial load in MSM taking PrEP?","authors":"Thibaut Vanbaelen, Irith De Baetselier, Agnès Libois, Chris Kenyon","doi":"10.1136/sextrans-2025-056550","DOIUrl":"https://doi.org/10.1136/sextrans-2025-056550","url":null,"abstract":"","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}