Schizophrenia Bulletin最新文献

{"title":"33 ANALYSIS OF THE TREATMENT OF COGNITIVE FUNCTION IN SCHIZOPHRENIA PATIENTS THROUGH TRADITIONAL CHINESE CULTURE READING","authors":"Fengtao Liu","doi":"10.1093/schbul/sbaf007.033","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.033","url":null,"abstract":"Background Schizophrenia is a serious mental illness characterized by sensory, cognitive, and emotional disorders. It often occurs in young and middle-aged individuals and can cause significant stress to the patient, their family, and society. Schizophrenia may also lead to symptoms such as sleep disorders, lack of concentration, and memory loss, which in turn affect the patient’s brain function and cognitive abilities. At present, the treatment of schizophrenia mainly relies on taking antipsychotic drugs, but it requires long-term medication and attention should be paid to avoiding drug dependence and side effects. Therefore, researching new treatment methods for schizophrenia without drug side effects is of great significance. Scholars have found that reading can stimulate the cerebral cortex, improve thinking ability and memory, which has a positive effect on maintaining and improving the brain function of psychiatric patients. Therefore, the study will explore the therapeutic effect of traditional Chinese cultural reading on cognitive function in patients with schizophrenia. Methods The study selected 74 patients with schizophrenia admitted to a tertiary hospital in a certain city from April 2021 to May 2023 as the research subjects. Randomly divide these patients into an observation group and a control group, with 37 patients in each group. The control group patients received routine care, while the observation group patients received an additional 3 hours of Chinese traditional culture reading every day on the basis of routine care. The experiment lasts for three months. Use the Scale for Assessment of Negative Symptoms (SANS) to evaluate the severity of patients’ symptoms before and after treatment, with higher scores indicating more severe symptoms. And use the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) to score the patient’s cognitive function, with higher scores indicating better cognitive function. SPSS 24.0 software was used for statistical analysis of the data, with P<0.05 indicating statistically significant differences. Results There was no significant difference in clinical general data between the two groups of patients (P>0.05), so a comparison can be made. Before treatment, there was no significant difference in LOTCA scores between the two groups of patients (P>0.05). After three months of treatment, the LOTCA score of the observation group was 64.24 ± 4.57, significantly higher than that of the control group patients (P<0.05). Before treatment, the SANS score of the control group patients was 67.05 ± 5.97, while the SANS score of the observation group was 67.12 ± 5.34, with no statistically significant difference (P>0.05). After three months of treatment, the SANS score of the observation group was 35.48 ± 2.02, significantly lower than that of the control group patients (P<0.05). Discussion With the transformation of modern medical models, the clinical treatment of","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"24 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143435035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"62 EFFECT OF CONTEMPORARY LITERATURE COMBINED WITH PSYCHOTHERAPY ON THE MENTAL HEALTH OF PEOPLE WITH MENTAL ILLNESSES","authors":"Yiying Su","doi":"10.1093/schbul/sbaf007.062","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.062","url":null,"abstract":"Background Schizophrenia, a chronic and disabling mental illness, affects approximately 1% of the world’s population. It is characterised by a range of symptoms including hallucinations, delusions, disturbed thinking and cognitive impairment. The traditional approach to treating schizophrenia has centred on antipsychotic medications and various forms of psychotherapy. However, recent research suggests that supplemental therapies such as complementary therapies supplemented with contemporary literature can enhance the effectiveness of traditional treatments by improving cognitive functioning and mood regulation. The aim of the study was to investigate the impact of integrating contemporary literature into psychotherapy on mental health outcomes for patients with schizophrenia. Methods A randomised controlled trial of 120 participants with schizophrenia diagnosed at our institution were selected for the study. All participants were divided into a control group and an intervention group of 60 participants each. The control group received standard treatment (antipsychotic medication and traditional psychotherapy) and the intervention group received the same standard treatment and a programme treatment involving reading and discussing contemporary literature. The intervention group participated in weekly programme treatments, reading and discussing selected works, focusing on themes related to mental health and personal experiences. The study used the Positive and Negative Symptom Scale (PANSS), the MATRICS Consensus Cognitive Battery (MCCB), and the Difficulties in Emotion Regulation Scale (DERS). Emotion Regulation Scale (DERS) were conducted to assess participants’ cognition and emotion. The entire experimental period was 12 months. Results Positive symptoms (hallucinations and delusions) decreased by 25% (P<0.05) and negative symptoms (social withdrawal and emotional flatness) decreased by 30% (P<0.05) in the intervention group after 12 months. Cognitive functioning in the intervention group as measured by the MCCB improved by 15% (P<0.05) compared to the control group. Emotion regulation in the intervention group improved DERS scores by 20% compared to the control group (P>0.05). The results showed that there was a correlation between the level of engagement with literature and the improvement of participants’ symptoms and cognitive functioning (R=0.56, P<0.001). Specific results are shown in Table 1. Discussion Findings suggest that integrating contemporary literature into psychotherapy can significantly improve mental health outcomes for people with schizophrenia. Using literature as a therapeutic tool appears to enhance emotional expression and cognitive engagement, leading to better symptom management and improved social functioning. The study highlights the potential of complementary therapies in mental health treatment and calls for further research into how literary engagement affects cognitive and affect","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"64 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143435280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"44 THE EMOTIONAL IMPACT OF VISUALLY COMMUNICATING DIVERSE REPRESENTATIONS ON PSYCHIATRIC PATIENTS","authors":"Jing Luo","doi":"10.1093/schbul/sbaf007.044","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.044","url":null,"abstract":"Background Mental illness is a disorder of brain function and a disease with serious psychological disorders. Usually, patients’ cognition, emotion, will and action behavior are manifested as continuous abnormalities. For psychiatric patients, seeking treatment and intervention can promote their recovery and social function recovery. At present, a variety of psychological, artistic and social intervention therapy is gradually used as a supplement or even substitute for drugs, and its clinical effect has been widely confirmed. Among them, the diversified expression of visual communication refers to the process of conveying information and emotions through various expressions such as color, graphics, fonts, layout and multimedia elements, which is expected to profoundly affect people’s emotional expression and perception. This study introduces it into the field of psychological intervention for psychiatric patients and explores its emotional impact on patients. Methods 40 patients who met the diagnostic criteria of psychosis were divided into experimental group and control group according to the principle of uniform and random, and the intervention period was set for 6 months. The control group received routine nursing treatment and did not participate in any form of intervention activities, while the experimental group received visual communication diversified expression intervention twice a week during the intervention cycle, and communicated with the visual communication designer through dynamic and interactive design with various elements. The scale was tested before intervention and at 2, 4 and 6 months after intervention. The measurement scales included Difficulties in Emotion Regulation Scale (DERS) and self-rating anxiety scale (self-rating Anxiety Scale). SAS, self-rating depression scale (SDS), and Emotional Intelligence Scale (EIS). Results The comparison results of DERS scale of different subjects before and after intervention are shown in Figure 1. As can be seen from Figure 1, there was no statistical difference in DERS scores between the two groups before intervention (P>0.05), and the subsequent experimental analysis was scientific and effective. After one month of intervention, DERS scores of the experimental group began to decline, and there was a statistical difference compared with the control group (P<0.05). When the intervention time reached 4 months, there was a statistically significant difference between the experimental group and the control group (P<0.01). After the intervention, the experimental group’s DERS score decreased from 68.167 to 48.496. In addition, the scores of SAS and SDS in both groups decreased, but the scores in the experimental group were lower than those in the control group, and the difference was statistically significant (P<0.05). Finally, the total score of EIS, emotional feeling score and ability to understand emotions of oneself or others in the experimental group were ","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"21 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143435470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"89 STUDY ON EMOTIONAL PERCEPTION OF SCHIZOPHRENIC PATIENTS WITH TRADITIONAL CULTURAL READING THERAPY COMBINED WITH DRUGS","authors":"Wei Bu","doi":"10.1093/schbul/sbaf007.089","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.089","url":null,"abstract":"Background Patients with schizophrenia are often accompanied by emotional disorders, including emotional flatness, emotional incongruity and impairment of emotional perception. These symptoms have a serious impact on patients’ social interaction and daily life functions. Although antipsychotic drugs can effectively control the positive symptoms of schizophrenia, they have limited effect on improving the negative symptoms and emotional perception of patients. As an auxiliary therapy, traditional cultural reading therapy can promote patients’ self-reflection and emotional expression through reading and discussing traditional cultural materials, and help improve patients’ emotional perception and social skills. In order to improve the emotional perception and social function of patients, the study comprehensively considered the potential positive effects of drug therapy and traditional cultural reading on mental rehabilitation. Methods Between January 2020 and December 2023, 60 long-stay schizophrenic patients admitted to a hospital were randomly assigned to a study group and a control group, with 30 people in each group. The control group received the usual care and medication, and worked to establish good communication with the patients to create a harmonious nurse-patient relationship. The nursing staff monitors the patient’s psychological changes, guides the patient’s negative emotions appropriately, and ensures that the patient follows the doctor’s instructions to take the medication correctly. The research team used reading therapy, which was equipped with multimedia devices such as VCD players and cable TV. Patients in the study group were divided into two groups, each group of 15 people, each group for 4 weeks to read books, usually 1 hour a day, divided into two sessions in the morning and afternoon. Patients were evaluated using Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS). Results Patients with schizophrenia who are hospitalized for a long period of time are often socially impaired, showing significant negative symptoms and varying degrees of positive symptoms. The analysis showed that there was no significant difference in negative emotion scores between the two groups before intervention (P > 0.05). However, after the intervention, the negative emotion score of the study group was lower than that of the control group, and the nursing satisfaction of the study group was significantly higher than that of the control group (P < 0.05). Since the patients are often accompanied by thinking disorders, lack of energy, anxiety and depression, social dysfunction is significant, therefore, providing reading therapy intervention to these patients can help improve their cognitive symptoms, negative symptoms, and social functioning. Discussion In practical application, reading therapy enables patients to discuss mental health issues after reading and understand their mental state more deeply, which proves that ","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"64 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143435471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"14 ANALYSIS OF THE EFFECTIVENESS OF DIGITAL EMOTION RECOGNITION DISPLAY DESIGN IN EARLY INTERVENTION FOR SCHIZOPHRENIA","authors":"Jia Liu, Xianjie Zhou*, Yue Sun","doi":"10.1093/schbul/sbaf007.014","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.014","url":null,"abstract":"Background Schizophrenia is a chronic and severe mental disorder characterized by disorders of thinking, hallucinations, delusions, and emotional and social dysfunction. Due to their unique psychological development stage and social environment, college students are of special importance for the early identification and intervention of schizophrenia. Early diagnosis and treatment of schizophrenia is essential to improve prognosis, reduce disability, and improve quality of life. However, due to the complexity and heterogeneity of schizophrenia, early diagnosis and treatment pathway selection face many challenges. Knowledge management, as a systematic approach, is able to integrate and optimize information, knowledge, and skills to provide support for the early diagnosis and treatment of schizophrenia. Study aims to explore how to through the perspective of knowledge management, combined with clinical symptoms, drug response, cognitive health and mental related factors, optimize the early diagnosis of schizophrenia and treatment path, and explore the special group of schizophrenia patients’ health care utilization and cost benefit, in order to provide more accurate and more effective mental health services for college students. Methods Using the case-control study method, 300 college students who met the diagnostic criteria for schizophrenia and 150 healthy college students were selected as the control group. By using neuroimaging techniques such as Functional Magnetic Resonance Imaging (fMRI) and Wisconsin Card Sorting Test (WCST), the cognitive and social functions of two groups of students were evaluated. Meanwhile, the visual scanning path pattern analysis technique was used to examine the patient’s ability to process facial emotion perception. After data collection, multiple linear regression analysis was used to explore the relationship between cognitive function, social function, and facial emotion perception and the severity of schizophrenia symptoms. Results The results showed that the schizophrenia patient group performed significantly less in cognitive function tests and social function assessment than the control group (P<0.01). Multiple linear regression analysis showed that cognitive function (β=0.65, P<0.001) and social function (β=0.52, P<0.001) were significant predictors of symptom severity in schizophrenia. In addition, there was a significant correlation between facial emotion perceptual processing ability and symptom severity (β=0.48, P<0.01). In terms of treatment pathway optimization, patient treatment adherence and quality of life can be significantly improved through knowledge management strategies such as patient education, family support and integration of community resources (P<0.05). Discussion The results reveal the key role of cognitive function, social function and facial emotional perception in the early recognition and intervention of schizophrenia. These dimensions not only serve","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"6 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"55 STUDY ON THE EFFECT OF MUSIC STRESS REDUCTION THERAPY ON SCHIZOPHRENIA OF FINANCIAL PRACTITIONERS","authors":"Yiqin Xie","doi":"10.1093/schbul/sbaf007.055","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.055","url":null,"abstract":"Background Workers in the financial industry generally face high pressure and high competition in the working environment, and have a high risk of mental health, including a high incidence of schizophrenia. Patients are usually accompanied by cognitive disorders, emotional disorders and impaired social functions, which seriously affect their quality of life and work ability. At present, the main use of drug intervention, but the efficacy is limited and may produce drug resistance and adverse reactions. Music therapy, which can regulate emotions, relieve stress and improve cognitive function, has gradually become a potential adjuvant therapy. However, there is a lack of systematic research on the effect of music therapy on financial practitioners with schizophrenia. The study evaluated the intervention effect of music therapy on the symptoms of financial practitioners, explored its application prospects and mechanisms, and provided references for personalized treatment programs. Methods A randomized controlled trial design was used to enroll 120 financial practitioners diagnosed with schizophrenia. All participants were randomly divided 1:1 into music therapy (n=60) and control (n=60) groups. The music therapy group received a 60-minute music therapy intervention twice a week for 12 weeks, in addition to their usual medication. Music therapy includes guided music listening, rhythmic interaction, and emotional expression activities that are personalized to match subjects’ musical preferences. The control group received only conventional drug treatment and no additional non-drug intervention. Symptom assessment measures included the Positive and Negative Syndrome Scale (PANSS) and the Beck Depression Inventory (BDI), which were measured at baseline, at week 6, and at the end of the intervention. In addition, acceptance and adherence to the intervention were assessed using satisfaction surveys. Results Baseline assessment showed no statistically significant differences in gender composition, mean age, duration of disease, or symptom score between the two groups (P>0.05). After the intervention, the total score of PANSS in the music therapy group was 62.3±12.4, while that in the control group was 73.5±11.2, which was significantly lower than that in the music therapy group (P<0.05). Further sub analysis showed that the negative symptom score of the music therapy group was 23.6±5.1, which was significantly lower than that of the control group (27.8±6.4, P<0.05). In terms of depressive symptoms, BDI scores in the music therapy group decreased from 28.5±6.8 to 18.4±5.2 at baseline (P<0.05), and BDI scores in the control group decreased from 28.7±7.0 to 23.4±6.7 (P<0.05). Discussion Our findings suggest that music stress reduction therapy significantly improves the clinical symptoms of financial practitioners with schizophrenia. By guiding emotional expression, relieving stress and promoting social interaction, music the","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"11 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143435005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"38 THE FUNCTION AND MECHANISM OF EXTRACELLULAR VESICLES IN POSTOPERATIVE COGNITIVE DYSFUNCTION","authors":"Jinmeng Ma","doi":"10.1093/schbul/sbaf007.038","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.038","url":null,"abstract":"Background Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients, showing a decline in memory, attention and executive function, which affects the quality of life and recovery. Exosomes, as mediators of cell-cell communication, have attracted much attention in neurological diseases, which contain a variety of bioactive molecules that can participate in the CNS regulation through the blood-brain barrier. Currently, the function and mechanism of exosomes in POCD remain unclear. The study will explore the role of exosome in POCD through animal experiments and molecular biology techniques, and provide new targets for clinical intervention. Methods Healthy adult male C57BL/6 mice weighing 20-25g were divided into Sham group (n=20), POCD group (n=30), and POCD intervention group (n=30). The POCD model was constructed by common carotid artery ligation and isoflurane anesthesia. Spatial learning and memory abilities were assessed on postoperative days 1,3, and 7 using the Morris water maze (MWM). After the experiment, the distribution in the brain of fluorescently labeled exosomes was visualized by tail vein injection, and the expression of miRNA and key proteins in the exosomes was analyzed by Reverse Transcription Quantitative Polymerase Chain Reaction (RT-qPCR) and proteomics techniques. The Western blot and immunofluorescence labeling techniques were used to verify the relationship between molecules and neuroinflammation in exosomes. Data were analyzed using the SPSS 26.0 software, and the differences between groups were compared by one-way analysis of variance (ANOVA). Results Comparison of the main indicators between the groups is shown in Table 1. Table 1 shows that mice in the POCD group had prolonged latency on postoperative days 1 and 3, shorter residence time in the target quadrant, and improved cognitive function in the intervention group. After exosome tail vein injection, the fluorescence signal was enhanced in the hippocampus, indicating that exosomes penetrate the blood-brain barrier. By RT-qPCR, inflammation-related miRNA expression was up-regulated in exosomes in the POCD group, with the expression decreased after intervention. Proteomic analysis showed that the expression of proteins related to IL-6, TNF- α, and NF- κ B signaling pathway was increased in exosomes in the POCD group, and decreased after intervention. Immunofluorescence showed that the proportion of Iba-1-positive microglia activation in the hippocampus of the POCD group was high and decreased after the intervention. Discussion The function and mechanism of exosomes in POCD were systematically investigated. The results indicate that exosomes can enter the CNS through the blood-brain barrier and affect neuroinflammation and cognitive function recovery in the hippocampus by regulating inflammation-related miRNA and protein expression. This provides new molecular targets and theoretical ale for POCD intervention. Future studies should furthe","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"6 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"70 RESEARCH ON THE ROLE OF VOCAL TRAINING IN IMPROVING COGNITIVE FUNCTION OF PATIENTS WITH SCHIZOPHRENIA","authors":"Jing Zhuang","doi":"10.1093/schbul/sbaf007.070","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.070","url":null,"abstract":"Background Schizophrenia patients exhibit sensory and behavioral abnormalities, and the current common intervention treatment mainly uses drugs to block dopamine receptors in the brain. However, the cognitive function of patients with schizophrenia cannot be cured through medication. In current interventions for schizophrenia, vocal training therapy can regulate the patient’s breathing rhythm, maintain their heart rate and emotions, relax their mood and body, thereby increasing their resistance to stressful situations. Therefore, the study explored the positive effects of vocal training on cognitive function training in patients with schizophrenia. Methods A study was conducted on 150 patients with schizophrenia, who were evenly divided into a control group and an experimental group, with 75 patients in each group. The control group received routine nursing methods and the nursing time was maintained for 6 months. The experimental group added soothing vocal training activities on the basis of routine care, twice a week for 30 minutes each time. The same intervention lasted for 6 months in the experimental group. After intervention, Stroop color word test was used to evaluate patients’ cognitive function. Results The study will evaluate the cognitive function level of patients with schizophrenia based on the Stroop color word test results before and after intervention in the experimental and control groups. The specific results are shown in Table 1. From the table, it can be seen that the control group scored 97.32±1.27 and 97.87±1.40 before and after intervention in the A card test, respectively. The scores of the experimental group before and after intervention were 97.65±1.27 and 99.70±0.46, respectively. In the detection of the B card, the scores of the control group before and after intervention were 94.75±1.77 and 95.18±2.22, respectively, while the detection scores of the experimental group were 95.10±1.66 and 98.73±1.04, respectively. In the C card, the scores of the control group before and after intervention were 87.20±3.83 and 88.08±3.76, respectively. The scores of the experimental group before and after intervention were 86.53±3.55 and 95.60±2.12, respectively. From the data results, it can be seen that the experimental group showed a greater increase in Stroop color word test scores after intervention, indicating that vocal training can effectively improve cognitive function in patients with schizophrenia. Discussion The experimental results indicate that the intervention method of vocal training can improve patients’ thinking expression ability and memory by soothing their physical and mental health, and through vocal music. Through vocal training, patients with schizophrenia can enhance their self-identity through beautiful musical works and singing behavior, thereby improving their psychological state and cognitive function, enhancing their self-management level and quality of life.","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"51 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"19 BEHAVIOR MODIFICATION IN SCHIZOPHRENIC PATIENTS WITH TRADITIONAL FAMILY CULTURE TREATED WITH PALIPERIDONE","authors":"Yang Meng*, Xilan Wang, Hongyan Lu","doi":"10.1093/schbul/sbaf007.019","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.019","url":null,"abstract":"Background Schizophrenia is a chronic mental illness characterized by cognitive, affective, and behavioral disorders, and its patients often exhibit impaired social functioning. In traditional Chinese culture, family training has an important influence on shaping personal behavior, and schizophrenia patients who are influenced by traditional family training culture may need additional patient behavior modification during treatment. Paliperidone, as a new antipsychotic drug, has attracted much attention for its significant therapeutic effect on patients with schizophrenia. This study explores the efficacy of behavior modification in patients with schizophrenia under the intervention of paliperidone treatment combined with traditional family training and cultural background intervention. Methods The study recruited 80 patients with schizophrenia, of whom 40 were exposed to traditional family training culture as the experimental group, and the remaining 40 were not exposed to traditional family training culture as the control group. All patients met the diagnostic criteria for schizophrenia in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). All patients signed informed consent. The study used the Positive and Negative Syndrome Scale (PANSS), the Social Disability Screening Schedule (SDSS) and the Behavioral Adaptation Scale (BAS) to evaluate the treatment effect of patients, and recorded the scale scores of different treatment cycles. Results The study compared and analyzed the BAS scale evaluation results of the two groups of patients and compared the scores of patients at different treatment times as shown in Table 1. As can be seen from Table 1, there are differences in the scores of schizophrenia patients under different treatment cycles, with the experimental group having the highest scale score. After 12 weeks of treatment, the scale score of the experimental group reached 49.2±4.2, and the scale score of the control group reached 42.7±4.8. There was a statistically significant difference between the scale scores of the two groups of patients (P<0.05). Except for no treatment, there were significant statistical differences in the scale scores of the two groups of patients during the other treatment cycles (P<0.05). It can be seen that through paliperidone treatment combined with family training and cultural intervention, the patient has significant therapeutic effects in behavioral modification treatment. Discussion The results of the study showed that traditional family education combined with paliperidone treatment can effectively improve the behavioral adaptability of patients with schizophrenia, especially for some patients who are deeply influenced by traditional culture. However, the intervention treatment plan for different patients’ education and family background needs to be further improved. The study aims to provide more valuable references for the practical application of drug combined with cultural","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"64 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"84 THE STRESS REGULATION OF PSYCHIATRIC PATIENTS THROUGH VR DIGITAL CULTURAL TOURISM","authors":"Xiaofen Wang, Fuxuan Liao, Zongfei Li, Lihua Han, Yanzhen Wang, Hang Li","doi":"10.1093/schbul/sbaf007.084","DOIUrl":"https://doi.org/10.1093/schbul/sbaf007.084","url":null,"abstract":"Background Virtual Reality (VR) digital tourism refers to the use of VR technology combined with digitalization to create virtual experiences with cultural and tourism elements. Through VR technology, users can immerse themselves in exploring various cultural heritage, historical scenes, tourist attractions, etc., achieving cultural and tourism experiences in virtual spaces. With the continuous advancement of VR technology, it has also been widely applied in the field of mental illness. VR technology can bring patients into a virtual environment and provide them with immersive therapy, effectively alleviating their symptoms. The research aims to explore the moderating effect of VR digital tourism on psychological stress in patients with schizophrenia, in order to provide guidance for clinical practice. Methods 56 patients diagnosed with schizophrenia in the Department of Psychiatry from January 2024 to June 2024 were selected from the First People’s Hospital of a certain city. The participants were randomly assigned to a VR digital tourism treatment group (28 patients) and a conventional treatment group (28 patients). The conventional treatment group received treatment through medication and psychological guidance, while the VR digital tourism treatment group provided patients with VR devices and selected virtual environments based on their needs for treatment. The treatment lasted for 3 months. Using SPSS 22.0 statistical software for data analysis, the status of patients with schizophrenia was evaluated through the Schizophrenia Quality of Life Scale (SQLS), which includes three dimensions: psychosocial, energy dynamics, and symptoms/side effects. Results The comparison results of the included patients’ SQL scores are shown in Table 1. Before intervention, the VR digital tourism treatment group scored 32.25 ± 5.08, 20.46 ± 4.17, and 22.38 ± 4.74 in the dimensions of psychosocial, energy dynamics, and symptom/side effects, respectively. After intervention, the VR digital tourism treatment group scored 23.86 ± 2.82, 14.58 ± 2.12, and 15.52 ± 2.02 in three dimensions, respectively. After intervention, the scores of the VR digital tourism treatment group in three dimensions were lower than before intervention, and the scores of the VR digital tourism treatment group after intervention were significantly lower than those of the conventional treatment group, with a significant difference between the two groups (P<0.05). Discussion VR digital tourism has a significant effect on stress regulation in patients with schizophrenia. VR technology can help patients with schizophrenia relax their body and mind, enjoy their mood, improve their sleep quality, and effectively regulate their stress by creating numerous high-quality scenes. Funding 2022YFF0902402; 2024-01; 22285801Z; ZD202121; 22375801D.","PeriodicalId":21530,"journal":{"name":"Schizophrenia Bulletin","volume":"80 1","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}