Revista espanola de fisiologia最新文献_第4页

Is the post-lunch dip in sprinting performance associated with the timing of food ingestion? 午餐后短跑成绩的下降与进食时间有关吗?

Revista espanola de fisiologia Pub Date : 1996-12-01

C Javierre, J L Ventura, R Segura, M Calvo, E Garrido

{"title":"Is the post-lunch dip in sprinting performance associated with the timing of food ingestion?","authors":"C Javierre, J L Ventura, R Segura, M Calvo, E Garrido","doi":"","DOIUrl":"","url":null,"abstract":"To detect whether the drop in performance around lunch has any direct association with the time of food ingestion, a group of 8 sprinters were studied for 5 consecutive Saturdays. On each testing day, the times achieved during 80 meter sprints performed at eight different times of the day separated by 2 hour intervals were recorded. The 1st and 4th testing days, had identical sleep and mealtime schedules, and were therefore considered \"control days\", while on the 2nd and 3rd testing days the schedule was brought forward (\"advanced\") or backward (\"delayed\") by 2 hours respectively. On the 5th testing day the sleep-wake cycle was brought forward 2 hours without changing the mealtime schedule. A post-lunch dip (PLD) was detected on all testing days although at different times. No significant differences in performance were observed between days 1 and 4 while there were differences in performance during the other testing days. It is worth pointing out that PLD occurred at about 15:00 h on the control days, with significant differences between the 2nd (p < 0.05) and 3rd days (p < 0.05), and with the deterioration in performance starting at 15:00 h on the 3rd day despite the fact that lunch had been served at 16:00 h. In conclusion, PLD does not appear to be directly linked to the time of lunch, although lunch itself could potentiate its effects. It is also worth mentioning the fact that this deteriorating effect does not occur after any other meals of the day.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 4","pages":"247-53"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20092980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in the hypothalamic serotonergic function may mediate the endocrine effects of melatonin. 下丘脑血清素功能的改变可能介导褪黑激素的内分泌作用。

Revista espanola de fisiologia Pub Date : 1996-12-01

J M Míguez, M Aldegunde

{"title":"Changes in the hypothalamic serotonergic function may mediate the endocrine effects of melatonin.","authors":"J M Míguez, M Aldegunde","doi":"","DOIUrl":"","url":null,"abstract":"The effects of a single injection of melatonin on serum thyroxine, corticosterone and prolactin levels, and the associated changes in the metabolism of serotonin (5-HT) in several hypothalamic regions of male rats kept under a 14-h light 10-h dark cycle (lights on at 08:00 h), are investigated. Melatonin (500 micrograms/kg, s.c.) or replacing saline was injected at 18:00 h, and 8 animals from treated and control groups were killed 1 h (19:00 h), 12 h (06:00 h) and 18 h (12:00 h) later. Melatonin significantly reduced serum thyroxine, corticosterone and prolactin levels within 1 h of treatment, indicating the existence of an acute inhibitory effect on hormonal secretion. Serum prolactin levels were increased 18 h after treatment, suggesting the implication of a different long-term regulatory mechanism. Injected melatonin induced several acute changes in the metabolism of 5-HT in the hypothalamus. Thus, a significant increase of 5-HT content in the preoptic area-anterior hypothalamic (POA-AH) and medial hypothalamic regions of melatonin-treated rats was observed within 1 h of treatment. The content of 5-hydroxyindoleacetic acid (5-HIAA) increased in medial hypothalamus, and the ratio 5-HIAA/5-HT decreased in POA-AH. The results show that melatonin acutely modifies the serotonergic activity in POA-AH and medial hypothalamus, and simultaneously inhibits thyroid, adrenal and pituitary hormonal secretion. The results are discussed suggesting that the hypothalamic serotonergic system could be an ideal mechanism underlying short-term melatonin effects on endocrine function.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 4","pages":"239-45"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20092979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hepatic and erythrocytic glutathione peroxidase activity in liver diseases. 肝脏和红细胞谷胱甘肽过氧化物酶活性与肝脏疾病。

Revista espanola de fisiologia Pub Date : 1996-09-01

R Cordero, A Ortiz, R Hernández, V López, M M Gómez, P Mena

{"title":"Hepatic and erythrocytic glutathione peroxidase activity in liver diseases.","authors":"R Cordero, A Ortiz, R Hernández, V López, M M Gómez, P Mena","doi":"","DOIUrl":"","url":null,"abstract":"Hepatic and erythrocytic glutathione peroxidase activity, together with malondialdehyde levels, were determined as indicators of peroxidation in 83 patients from whom liver biopsies had been taken for diagnostic purposes. On histological study, the patients were classified into groups as minimal changes (including normal liver), steatosis, alcoholic hepatitis, hepatic cirrhosis, light to moderately active chronic hepatitis, and severe chronic active hepatitis. The glutathione peroxidase activity in erythrocytes showed no significant changes in any liver disease group. In the hepatic study, an increased activity was observed in steatosis with respect to the minimal changes group, this increased activity induced by the toxic agent in the initial stages of the alcoholic hepatic disease declining as the hepatic damage progressed. There was a negative correlation between the levels of hepatic malondialdehyde and hepatic glutathione peroxidase in subjects with minimal changes. This suggested the existence of an oxidative equilibrium in this group. This equilibrium is broken in the liver disease groups as was manifest in a positive correlation between malondialdehyde and glutathione peroxidase activity.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 3","pages":"167-72"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19937499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-feeding carbohydrate and ketone bodies metabolism in brain and liver of Atlantic salmon. 大西洋鲑鱼饲喂后脑和肝脏碳水化合物和酮体代谢。

Revista espanola de fisiologia Pub Date : 1996-09-01

J L Soengas, E F Strong, J Fuentes, M Aldegunde, M D Andrés

引用次数: 0

Ha-ras in normal and tumoral tissues: structure, function and regulation. Ha-ras在正常和肿瘤组织中的结构、功能和调控。

Revista espanola de fisiologia Pub Date : 1996-09-01

M Solanas, E Escrich

引用次数: 0

Lymphocyte subpopulations and catecholamines; daytime variations and relationships. 淋巴细胞亚群与儿茶酚胺;白天的变化和关系。

Revista espanola de fisiologia Pub Date : 1996-09-01

J R Infante, F Perán, M Martínez, R Poyatos, A Roldán, C Ruiz, F Garrido

{"title":"Lymphocyte subpopulations and catecholamines; daytime variations and relationships.","authors":"J R Infante, F Perán, M Martínez, R Poyatos, A Roldán, C Ruiz, F Garrido","doi":"","DOIUrl":"","url":null,"abstract":"The diurnal variations and their possible relations with endogenous catecholamines have been studied in 16 apparently healthy subjects (8 women and 8 men, between 22-35 years of age). A butterfly cannula was inserted into the flexure vein of the elbow at 8 h and at 20 h, a blood sample being taken after three 15-minute intervals. Leukocytes, lymphocytes, monocytes, and granulocytes were quantified in a cell counter while lymphocyte subpopulations were determined with flow cytometry in cells labelled with specific monoclonal antibodies. Plasma catecholamine concentrations were measured by high-pressure liquid chromatography. Significant differences for leukocyte circulating levels were found, as well as for all subpopulations measured at different times of day, save NK cells and monocytes. A statistically significant correlation was also found both between leukocytes, all subpopulations and epinephrine save B lymphocytes and NK cells, and between total lymphocytes, T lymphocytes, CD4, CD4/45RA+ subtypes and norepinephrine. In conclusion, diurnal rhythms were proved to exist in leukocyte and lymphocyte subpopulations; the significant correlation between these cells and catecholamine plasma levels suggests the presence of a possible mechanism that connects the cellular immunity with determined hormones.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 3","pages":"143-8"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19937495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developmental changes of soluble and membrane-bound aspartate aminopeptidase activities in rat brain. 大鼠脑内可溶性和膜结合天冬氨酸氨基肽酶活性的发育变化。

Revista espanola de fisiologia Pub Date : 1996-09-01

G Arechaga, B Sánchez, F Alba, J D Luna, I Prieto, J M Martínez, M Ramírez

{"title":"Developmental changes of soluble and membrane-bound aspartate aminopeptidase activities in rat brain.","authors":"G Arechaga, B Sánchez, F Alba, J D Luna, I Prieto, J M Martínez, M Ramírez","doi":"","DOIUrl":"","url":null,"abstract":"Specific soluble and membrane-bound aspartyl-naphthylamide hydrolyzing activities were assayed in brain subcellular fractions from rat fetuses (19-20 days of gestation), and from 1-week-old and 1-, 5- and 24-month-old rats. Both enzymatic activities showed a heterogeneous distribution, with highest concentrations mainly in the microsomal fraction. Membrane-bound activity was in most cases higher than soluble activity. With the exception of soluble activity in the nuclear and microsomal fractions, significant age-related changes were observed in all fractions for both enzymatic activities. Soluble activity showed a homogeneous developmental profile in most of the fractions, with the lowest levels in 1-month-old rats and the highest in 1-week and 5-month-old animals. However, changes in the microsomal fraction did not follow the pattern displayed by the rest of the fractions. No clear developmental profile in specific membrane-bound activity was observed, each fraction exhibiting a different sequence of changes. Whereas in 24-month-old-rats there was a significant increase in activity in homogenate, nuclear and microsomal fractions, a significant decrease was observed in the synaptosomal fraction. These results may reflect the functional status of the endogenous substrates of the enzymes.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 3","pages":"149-54"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19937496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exogenous substrates as energy source for the contractile activity of the isolated rat tail artery. 外源性底物作为离体大鼠尾动脉收缩活动的能量来源。

Revista espanola de fisiologia Pub Date : 1996-09-01

E A Savino, A Varela, M Carregal

引用次数: 0

Effects of cyclosporine on circulating levels of prolactin, LH, FSH, TSH and GH in chronic hyperprolactinemic male rats. 环孢素对慢性高泌乳素血症雄性大鼠循环中催乳素、LH、FSH、TSH和GH水平的影响。

Revista espanola de fisiologia Pub Date : 1996-09-01

A Lafuente, E Alvarez-Demanuel, A Blanco, M García-Bonacho, A I Esquifino

{"title":"Effects of cyclosporine on circulating levels of prolactin, LH, FSH, TSH and GH in chronic hyperprolactinemic male rats.","authors":"A Lafuente, E Alvarez-Demanuel, A Blanco, M García-Bonacho, A I Esquifino","doi":"","DOIUrl":"","url":null,"abstract":"The effects of cyclosporine (CyA) on pituitary hormone secretion in animals with previously high plasma prolactin levels have been studied. Hyperprolactinemia was either induced in 30 day old male rats by the transplantation of one anterior pituitary gland from a litter mate donor or they were sham-operated to be used as controls. Both pituitary-grafted and sham-operated animals were injected s.c. with the vehicle or CyA (5 mg/kg weight per day) for 10 days, beginning 30 days after surgery. As expected, pituitary grafting markedly increased plasma prolactin levels as compared with the values found in control animals. Hyperprolactinemia was associated with reduced plasma LH and GH levels, increased plasma TSH levels and with no changes in circulating FSH levels. CyA administration to control animals increased plasma prolactin and TSH levels, decreased plasma levels of LH and did not modify circulating values of FSH and GH. Furthermore, CyA administration to pituitary-grafted animals decreased plasma prolactin and TSH levels, whereas plasma concentrations of GH and gonadotropins did not change. These data suggest that CyA differentially affect the release of pituitary hormones and that there is an interrelationship between previously high plasma prolactin levels and CyA to modulate pituitary hormone secretion.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 3","pages":"161-6"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19937498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic effects of the combination of furosemide and captopril in rat. 速尿与卡托普利联用对大鼠代谢的影响。

Revista espanola de fisiologia Pub Date : 1996-06-01

R López, C Taboada, C Rivas, A San Miguel

引用次数: 0