Saudi Medical Journal最新文献_第6页

Knowledge, attitudes, and perceptions of developmental dysplasia of the hip among pregnant women in Jordan. 约旦孕妇对髋关节发育不良的认识、态度和看法。

IF 1.5 4区医学

Saudi Medical Journal Pub Date : 2025-07-01 DOI: 10.15537/smj.2025.46.7.20241131

Khalaf A Alnowaishiri, Jehad E Khader, Waleed K Alkanderi, Sami M Alshiyab, Kamel A Jaber, Omar Q Samarah

{"title":"Knowledge, attitudes, and perceptions of developmental dysplasia of the hip among pregnant women in Jordan.","authors":"Khalaf A Alnowaishiri, Jehad E Khader, Waleed K Alkanderi, Sami M Alshiyab, Kamel A Jaber, Omar Q Samarah","doi":"10.15537/smj.2025.46.7.20241131","DOIUrl":"10.15537/smj.2025.46.7.20241131","url":null,"abstract":"Objectives: To assess the awareness of developmental dysplasia of the hip (DDH) among pregnant women in Jordan.Methods: A descriptive cross-sectional study was carried out among pregnant females, aged 18 years and above, who had visited 3 hospitals in Jordan. Data were collected through face-to-face interviews, and responses were recorded using a Google form by the researchers.Results: A total of 605 women completed the questionnaire. Most participants correctly reported DDH as the cause of ambulation problems (n=531, 87.6%), and approximately 60% reported it as painful. The majority agreed that DDH is diagnosed using x-ray imaging (80.5%), usually in the first 6 months of life (85.8%). In all, 37.3% of the participating women reported a family history of diagnosed DDH. Multivariate logistic regression analysis of participants' demographic and family variables demonstrated that those who possessed a college degree, those who had one or more children and those who had a diagnosis of DDH in the family were more aware of DDH than other participants (p=0.039, p=0.000, and p=0.025, respectively).Conclusion: There is an inconsistency between the level of awareness among the participants and the incidence of late-diagnosed DDH.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 7","pages":"831-835"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of dupilumab in chronic rhinosinusitis with nasal polyps: A retrospective study of clinical and imaging outcomes. dupilumab治疗慢性鼻窦炎伴鼻息肉的有效性：临床和影像学结果的回顾性研究。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-07-01 DOI: 10.15537/smj.2025.46.7.20241154

Mohammed A Alhejaily, Musallam Kashoob, Shatha Y AlGhamdi, Muhannad A Alomar, Yazeed A Alomar, Rawan S Alzayed, Amany M Altoies, Ahmad Alroqi

{"title":"Effectiveness of dupilumab in chronic rhinosinusitis with nasal polyps: A retrospective study of clinical and imaging outcomes.","authors":"Mohammed A Alhejaily, Musallam Kashoob, Shatha Y AlGhamdi, Muhannad A Alomar, Yazeed A Alomar, Rawan S Alzayed, Amany M Altoies, Ahmad Alroqi","doi":"10.15537/smj.2025.46.7.20241154","DOIUrl":"10.15537/smj.2025.46.7.20241154","url":null,"abstract":"Objectives: To evaluate dupilumab's outcomes in chronic rhinosinusitis with nasal polyps (CRSwNP) cases.Methods: A retrospective analysis was carried out at Dr. Sulaiman Al Habib Hospitals, Riyadh, Saudi Arabia on 145 adult CRSwNP patients treated with dupilumab between January 2020 and December 2023 following the European position paper on rhinosinusitis and nasal polyps 2020 guidelines. Primary outcomes included changes in Lund-Mackay computed tomography (CT) scores, immunoglobulin E levels, and visual analog scale (VAS) smell score over +12 months.Results: Significant improvements were noted post-treatment. Lund-Mackay CT scores decreased from 12.5 to 5.5 (p<0.001), and VAS smell scores dropped from 10.0 to 0.0 (p<0.001). Immunoglobulin E levels reduced from 250.5 to 63.5 (p<0.001). After treatment, 93.3% of patients avoided sinus surgery, 78.6% reported improved asthma status, and 60% used dupilumab as monotherapy.Conclusion: This study supports dupilumab's effectiveness in treating severe CRSwNP, showing significant improvements in CT imaging and overall medical condition over 12 months. Dupilumab reduced systemic corticosteroid use and rescue surgeries. While promising, further trials are needed to validate its use as monotherapy. Identifying those who gain most from biologic therapy is crucial.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 7","pages":"781-787"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of radial extracorporeal shockwave therapy combined with evidence-based physical therapy for adhesive capsulitis of the shoulder: A randomized controlled trial. 桡骨体外冲击波联合循证物理治疗肩关节粘连性囊炎的疗效：一项随机对照试验。

IF 1.5 4区医学

Saudi Medical Journal Pub Date : 2025-07-01 DOI: 10.15537/smj.2025.46.7.20250213

Turki M Sharahili, Hosam A Alzahrani

{"title":"Effect of radial extracorporeal shockwave therapy combined with evidence-based physical therapy for adhesive capsulitis of the shoulder: A randomized controlled trial.","authors":"Turki M Sharahili, Hosam A Alzahrani","doi":"10.15537/smj.2025.46.7.20250213","DOIUrl":"10.15537/smj.2025.46.7.20250213","url":null,"abstract":"Objectives: To evaluate the effect of radial extracorporeal shockwave therapy (rESWT) combined with evidence-based physical therapy (EBPT) on adhesive capsulitis (AC).Methods: A total of 30 participants with AC were randomly assigned to receive either rESWT combined with EBPT (experimental group) or sham rESWT combined with EBPT (control group) over a 6-week intervention period. The primary outcomes included pain (assessed using the visual analogue scale) and disability (disabilities of the arm, shoulder, and hand questionnaire). The secondary outcomes were shoulder range of motion (ROM), psychological distress (depression anxiety and stress scale-12), and health-related quality of life (HRQoL; short form-12). Assessments were carried out at baseline, post-intervention, and 12 weeks post-randomization.Results: Compared with the control group, the experimental group experienced better improvement in reduction of pain immediately post-intervention (-2.00, 95% confidence interval [CI]: [-3.43, -0.57]; p=0.008), at 12 weeks post-randomization (-3.33, 95% CI: [-4.71, -1.96]; p<0.001), and disability at 12 weeks post-randomization (-24.70, 95% CI: [-37.30, -12.10]; p<0.001). The experimental group showed better active ROM of the shoulder in flexion, abduction, and internal rotation at 12 weeks post-randomization, and better external rotation immediately post-intervention and at 12 weeks post-randomization. The experimental group achieved better passive ROM in abduction and external rotation immediately post-intervention and better flexion, abduction, external rotation, and HRQoL at 12 weeks post-randomization.Conclusion: The rESWT and EBPT combination therapy effectively decreased pain and disability and improved ROM and HRQoL in patients with AC.ClinicalTrials.gov Reg. No. ID: NCT05771220.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 7","pages":"816-824"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Illuminating the role of VEGFA and EGFR in head and neck squamous cell carcinoma through the multi-omics data integration. 通过多组学数据整合阐明VEGFA和EGFR在头颈部鳞状细胞癌中的作用。

IF 1.5 4区医学

Saudi Medical Journal Pub Date : 2025-07-01 DOI: 10.15537/smj.2025.46.7.20240775

Alaa S Alhegaili, Mohammed Alissa, Abdullah Alghamdi

{"title":"Illuminating the role of VEGFA and EGFR in head and neck squamous cell carcinoma through the multi-omics data integration.","authors":"Alaa S Alhegaili, Mohammed Alissa, Abdullah Alghamdi","doi":"10.15537/smj.2025.46.7.20240775","DOIUrl":"10.15537/smj.2025.46.7.20240775","url":null,"abstract":"Objectives: To investigate the functions of 2 crucial wound-healing genes, vascular endothelial growth factor-A (VEGFA) and epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinoma (HNSCC).Methods: This observational study, carried out between January and August 2024 in Saudi Arabia, involved 20 HNSCC and 10 normal oral cell lines sourced from The American type culture collection. Cell lines were cultured and gene expression was analyzed via RT-qPCR and Western blotting. Promoter methylation and mutational analyses were carried out using databases like UALCAN and cBioPortal. Functional assays, including cell proliferation, colony formation, and wound healing, were carried out to evaluate the effects of VEGFA and EGFR gene silencing using siRNA.Results: Expression analysis of 20 HNSCC cell lines showed significant upregulation of VEGFA and EGFR, confirming their potential as biomarkers. Receiver operating characteristic curve analysis further supported their discriminatory capabilities. Promoter methylation analysis revealed hypomethylation of both genes in HNSCC. Validation confirmed elevated mRNA and protein expression, especially in advanced stages. Mutational analysis indicated infrequent mutations. A prognostic model showed a correlation between higher VEGFA and EGFR expression and reduced overall survival. Knockdown experiments in human oral squamous carcinoma-3 cells reduced growth, and DrugBank identified Simvastatin as a potential therapeutic, with molecular docking showing strong interactions.Conclusion: This study highlights VEGFA and EGFR as diagnostic, prognostic, and therapeutic targets in HNSCC.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 7","pages":"768-780"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Segmentation with artificial intelligence and automated calculation of the corpus callosum index in multiple sclerosis. 人工智能分割及多发性硬化症胼胝体指数自动计算。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-06-01 DOI: 10.15537/smj.2025.46.6.20240957

Selahattin Demirbas, Kamil Karaali, Yalcın Albayrak, Nurdan Fidan

{"title":"Segmentation with artificial intelligence and automated calculation of the corpus callosum index in multiple sclerosis.","authors":"Selahattin Demirbas, Kamil Karaali, Yalcın Albayrak, Nurdan Fidan","doi":"10.15537/smj.2025.46.6.20240957","DOIUrl":"10.15537/smj.2025.46.6.20240957","url":null,"abstract":"Objectives: To determine the corpus callosum index (CCI) differences between chronic phase multiple sclerosis (MS) patients and healthy individuals and to evaluate the corpus callosum segmentation in MS patients using artificial intelligence technologies. The CCI can be reliably measured on magnetic resonance imaging (MRI) and has been proposed as a possible marker of brain atrophy in MS.Methods: In this study, 150 MS patients (disease duration 12.6±5.9 years) and 150 healthy control subjects were scanned. Corpus callosum index was manually measured from the mid-sagittal slices on MRI. A deep learning architecture-based U-Net model was used for automatic corpus callosum segmentation from 2D brain MRI.Results: The CCI score was calculated as mean 0.274 in the patient group and 0.382 in the control group (p=0.01). According to the ROC analysis, it was observed that the CCI measurement had a discrimination rate of 98.3% between groups with a cut-off value of 0.334. Sensitivity and specificity were calculated as 94%. The mean CCI calculated automatically after segmentation in the patient group was 0.286.Conclusion: Corpus callosum index is a method with high sensitivity and specificity in respect of determining corpus callosum atrophy in patients with MS in the chronic phase. Artificial intelligence technologies such as segmentation, machine learning, and deep learning to determine corpus callosum atrophy were seen to be successful in MS patients and the automatically calculated CCI score was successful in showing atrophy.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 6","pages":"638-648"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of genetic variants in patients with primary and secondary amenorrhea. 原发性和继发性闭经患者基因变异的鉴定。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-06-01 DOI: 10.15537/smj.2025.46.6.20250205

Flora Bai, Renjini Nambiar, Chirayu Padhiar, Wilson Aruni, Chinnadurai Veeramani, Mohammed A Alsaif, Khalid S Al-Numair

{"title":"Identification of genetic variants in patients with primary and secondary amenorrhea.","authors":"Flora Bai, Renjini Nambiar, Chirayu Padhiar, Wilson Aruni, Chinnadurai Veeramani, Mohammed A Alsaif, Khalid S Al-Numair","doi":"10.15537/smj.2025.46.6.20250205","DOIUrl":"10.15537/smj.2025.46.6.20250205","url":null,"abstract":"Objectives: To identify the cytogenetic and molecular pattern abnormalities and early diagnose the cause of primary and secondary amenorrhea.Methods: A total of 320 patients in the age group of 14-35 years with clinically confirmed amenorrhea were screened using conventional cytogenetic methods. Patients with a normal karyotype, hypoplastic uterus, and no hormonal imbalance were extensively investigated using molecular cytogenetic platforms such as chromosomal microarrays and clinical exome sequencing (CES).Results: Of the 266 patients with primary amenorrhea and 54 with secondary amenorrhea, 66.9% and 88.9%, independently, had a normal karyotype. The 20 patients with a normal karyotype, hypoplastic uterus, and no hormonal imbalance were further evaluated for microdeletions of <5 megabases using chromosomal microarray. In 20 cases, 5 samples with no microdeletions were investigated for 150 target genes using CES. A pathogenic variant at chromosome X BMP15, c.661T>C, p.W221R, HET-XL-VUS was observed in one patient (reclassification).Conclusion: Cytogenetic evaluation of women with amenorrhea was performed in this study. One of the main etiological factors for primary amenorrhea is aberrant karyotypes. Identifying the underlying genetic cause may aid in devising effective treatment strategies. In addition, early diagnosis may enable treatment planning by the family before amenorrhea occurs.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 6","pages":"659-669"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of very high cholesterol levels in asymptomatic military recruits: A single center study. 无症状新兵中非常高胆固醇水平的流行：一项单中心研究

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-06-01 DOI: 10.15537/smj.2025.46.6.20250177

Ghada A Rashwan, Hadiza O Ibrahim, Adil I Jumani, Rima Y Alsayari, Majdi S Alnajjar, Khalid M Alfakih

{"title":"Prevalence of very high cholesterol levels in asymptomatic military recruits: A single center study.","authors":"Ghada A Rashwan, Hadiza O Ibrahim, Adil I Jumani, Rima Y Alsayari, Majdi S Alnajjar, Khalid M Alfakih","doi":"10.15537/smj.2025.46.6.20250177","DOIUrl":"10.15537/smj.2025.46.6.20250177","url":null,"abstract":"Objectives: To determine the prevalence of very high low-density lipoprotein cholesterol (LDL-C) levels (≥4.9 mmol/L) among asymptomatic military recruits in the United Arab Emirates (UAE). Familial hypercholesterolemia (FH) is an underdiagnosed genetic disorder associated with significantly elevated LDL-C levels, increasing the risk of premature atherosclerotic cardiovascular disease (ASCVD).Methods: A cross-sectional study was conducted at Zayed Military Hospital in Abu Dhabi, UAE, between August 2023 and July 2024. 30,000 UAE national military recruits aged 17 to 40 underwent routine lipid screening. Electronic medical records (EMRs) were reviewed, and individuals with LDL-C ≥4.9 mmol/L were identified.Results: Among the participants, 596 (2%) had LDL-C levels ≥4.9 mmol/L, with a mean age of 25. The vast majority were male (96.8%), with only 3.2% being females. The highest recorded LDL-C level was 9.6 mmol/L. The mean height was 171.1 cm, the mean weight was 77.6 kg, and the mean body mass index was 26.6 kg/m2.Conclusion: This study highlights a notably high prevalence of very high LDL-C levels among young, asymptomatic UAE military recruits, suggesting a potentially undiagnosed burden of FH. Given the early risk of ASCVD, genetic screening and early intervention strategies should be explored for high risk individuals to facilitate early diagnosis and management.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 6","pages":"624-628"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of HBsAg and HBeAg seroconversion rates in patients diagnosed with chronic hepatitis B: A 10-year retrospective analysis. 慢性乙型肝炎患者HBsAg和HBeAg血清转换率的评估：10年回顾性分析

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-06-01 DOI: 10.15537/smj.2025.46.6.20241004

Müge Toygar Deniz, Muhammed Fatih Karaşın, İrem Asena Doğan Öntaş, Sıla Akhan

{"title":"Evaluation of HBsAg and HBeAg seroconversion rates in patients diagnosed with chronic hepatitis B: A 10-year retrospective analysis.","authors":"Müge Toygar Deniz, Muhammed Fatih Karaşın, İrem Asena Doğan Öntaş, Sıla Akhan","doi":"10.15537/smj.2025.46.6.20241004","DOIUrl":"10.15537/smj.2025.46.6.20241004","url":null,"abstract":"Objectives: To analyze the seroconversion rates over a ten-year follow-up period. Chronic hepatitis B (CHB) remains a critical public health concern globally. The seroconversion rates of hepatitis B surface antigen (HBs Ag) and hepatitis B e antigen (HBe Ag) are pivotal in evaluating treatment efficacy. Treatment cessation is guided by the identification of patients who have HBsAg seroclearance and HBeAg seroconversion.Methods: A 2,300 CHB patients treated with nucleos(t)ide analogues (NUCs) from 2013 to 2023 included the study. Based on their alanine aminotransferase (ALT) levels and HBeAg status, patients were divided into four phases and assessed the rates of HBsAg seroclearance and HBeAg seroconversion.Results: Among the 114 analyzed patients, HBsAg seroclearance occurred in 18 individuals (0.7%), and HBeAg seroconversion was documented in 53 patients. A significantly higher rate of HBeAg seroconversion in patients treated with Tenofovir Disoproxil Fumarate (TDF) compared to Entecavir (ETV). The mean time to HBeAg seroconversion with TDF demonstrating a faster response. Notably, TDF was also prominent among those achieving HBsAg seroclearance.Conclusion: This study underscores the potential superiority of TDF over ETV in facilitating seroconversion. The findings highlight the critical role of antiviral therapy in managing CHB and prompt further investigation influencing treatment outcomes.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 6","pages":"702-705"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring faculty perspectives on critical thinking in medical education: Challenges, strategies, and institutional support. 探索教师对医学教育中批判性思维的看法：挑战、策略和制度支持。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-06-01 DOI: 10.15537/smj.2025.46.6.20250148

Munirah A Batarfi, Sajida Agha

{"title":"Exploring faculty perspectives on critical thinking in medical education: Challenges, strategies, and institutional support.","authors":"Munirah A Batarfi, Sajida Agha","doi":"10.15537/smj.2025.46.6.20250148","DOIUrl":"10.15537/smj.2025.46.6.20250148","url":null,"abstract":"Objectives: To uncover faculty members' understanding, their teaching methods, and the challenges in promoting critical thinking skills among students. Critical thinking (CT) is a reflective process that involves analyzing, evaluating, and applying clinical evidence to make informed decisions that improve patient care. This study delves into the application of critical thinking in medical education, exploring various perspectives. Critical thinking necessitates thoughtful teaching approaches and ongoing educator development.Methods: Utilizing a phenomenographic approach, thirteen faculty members at King Saud bin Abdulaziz University for Health Sciences participated in semi-structured interviews conducted via Microsoft Teams. Interview transcripts were thematically analyzed using MAXQDA software.Results: The analysis identified five main themes concerning critical thinking at KSAU-HS, covering its definition, implementation, challenges, importance, and impact on the educational environment. These themes provide comprehensive insights into critical thinking's significance, challenges, and implications on teaching and learning.Conclusion: Faculty stress on critical thinking's importance for students' academic and professional success. They perceive the integration of critical thinking into teaching strategies and embedded in curriculum will significantly enhance cognitive abilities, contributing to students' overall development.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 6","pages":"670-678"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors influencing pain, anxiety, and comfort in patients undergoing coronary angiography: A prospective observational study. 影响冠状动脉造影患者疼痛、焦虑和舒适度的因素：一项前瞻性观察研究。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2025-06-01 DOI: 10.15537/smj.2025.46.6.20240158

Ganime E Soysal, Seyma Demir Erbas

{"title":"Factors influencing pain, anxiety, and comfort in patients undergoing coronary angiography: A prospective observational study.","authors":"Ganime E Soysal, Seyma Demir Erbas","doi":"10.15537/smj.2025.46.6.20240158","DOIUrl":"10.15537/smj.2025.46.6.20240158","url":null,"abstract":"Objectives: To investigate the factors associated with pain, anxiety and comfort in patients undergoing coronary angiography. Additionally, the relationship between pain, anxiety and comfort was examined.Methods: This observational study included 214 patients who underwent coronary angiography at Abant Izzet Baysal University Hospital in Bolu, Turkey, between October 2022 and December 2023. Demographic information, anxiety, and pain were recorded before and after the procedure, and comfort levels were recorded after the procedure. State-Trait anxiety inventory (STAI-State and Continuous), Paranesthesia Comfort Questionnaire (PCQ), General Comfort Questionnaire (GCQ) scales were used for analyses.Results: The patients were mostly male (67.3%) and had chest pain (75.7%). The analysis revealed that both the pre-STAI-State, and post-STAI-Continuous scores were elevated in the female demographic(p≤0.05). A statistically significant difference was observed in the pre-STAI-State score of patients diagnosed with hypertension. The study further demonstrated that individuals who were provided with comprehensive information regarding the procedure prior to coronary angiography exhibited higher pre-procedure STAI-Status scores, and lower PCQ. There was a statistically significant positive relationship between pain and both the pre-post STAI-State and the post-STAI-Continuous, but at a low level (r=0.256 and r=0.379, respectively; p<0.001).Conclusion: This study reveals the factors influencing patients' anxiety levels post-coronary angiography. Gender significantly impacts anxiety, and comfort levels. These findings emphasize the importance of psychological support and personalized patient information during coronary angiography(Clinical Trials Register:NCT06266117).","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 6","pages":"679-687"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0