Scandinavian Journal of Rheumatology最新文献_第3页

Baricitinib for skin vasculitis in primary Sjögren's disease: report of two cases. 巴西替尼治疗原发性Sjögren病皮肤血管炎2例报告。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-04-25 DOI: 10.1080/03009742.2025.2488098

G Hernández-Molina

引用次数: 0

Exploratory study of predictors of decreased ability to perform activities of daily living in people living with hand osteoarthritis. 手骨关节炎患者日常生活能力下降预测因素的探索性研究。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-04-24 DOI: 10.1080/03009742.2025.2484127

U Andersen, A Døssing, H Gudbergsen, V Hagelskjaer, H Bliddal, E E Wæhrens

{"title":"Exploratory study of predictors of decreased ability to perform activities of daily living in people living with hand osteoarthritis.","authors":"U Andersen, A Døssing, H Gudbergsen, V Hagelskjaer, H Bliddal, E E Wæhrens","doi":"10.1080/03009742.2025.2484127","DOIUrl":"https://doi.org/10.1080/03009742.2025.2484127","url":null,"abstract":"Objective: People with hand osteoarthritis (OA) report decreased ability to perform activities of daily living (ADL). However, few are referred to occupational therapy by their general practitioner. This study aimed to identify clinical predictors of decreased ADL ability in people with hand OA as markers of the need for referral to occupational therapy.Method: A cross-sectional study was conducted as an independent add-on to a randomized controlled trial of adults with hand OA (the COLOR trial). Measures of self-reported (ADL Interview) and observed (Assessment of Motor and Process Skills) ADL ability were collected. Data representing potential predictors identified by stakeholders were extracted from the COLOR trial: age, sex, symptom duration, hand OA type, grip strength, pain, stiffness, function, illness perception, and health-related quality of life. Correlational analyses and prediction models were used.Results: Correlations between ADL ability and potential predictors in the 62 participants were low to negligible (r < 0.5). Based on root mean square error (RMSE) estimates, prediction models for observed ADL motor (RMSE = 0.3) and ADL process (RMSE = 0.2) ability were more accurate than for self-reported ADL ability (RMSE = 0.6). However, these variables only predicted observed ADL motor and ADL process ability with 16% (adjusted Rs = 0.163) and 12% (adjusted Rs = 0.120) accuracy, respectively.Conclusion: The findings suggest that variables representing body functions, perceived health, and quality of life do not predict ADL ability among people living with hand OA. An adequately powered study is recommended to explore this topic further.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"1-9"},"PeriodicalIF":2.2,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translation, cross-cultural adaptation, and reliability of the EULAR Systemic Sclerosis Impact of Disease (ScleroID) questionnaire in a Danish population. 丹麦人群中EULAR系统性硬化症影响（ScleroID）问卷的翻译、跨文化适应和可靠性

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-04-03 DOI: 10.1080/03009742.2025.2480910

F N Foldager, J Beck Larsen, A Christensen, J Laursen, S Egsgaard, J Brincks, M Godt Hansen, M Pilegaard, M Ladefoged Assmann, A de Thurah, K Søndergaard, I Mechlenburg

{"title":"Translation, cross-cultural adaptation, and reliability of the EULAR Systemic Sclerosis Impact of Disease (ScleroID) questionnaire in a Danish population.","authors":"F N Foldager, J Beck Larsen, A Christensen, J Laursen, S Egsgaard, J Brincks, M Godt Hansen, M Pilegaard, M Ladefoged Assmann, A de Thurah, K Søndergaard, I Mechlenburg","doi":"10.1080/03009742.2025.2480910","DOIUrl":"https://doi.org/10.1080/03009742.2025.2480910","url":null,"abstract":"Objectives: This study aims to translate and cross-culturally adapt the European Alliance of Associations for Rheumatology (EULAR) Systemic Sclerosis Impact of Disease (ScleroID) questionnaire to Danish; and to assess its reliability in patients with systemic sclerosis (SSc).Method: The translation and cross-cultural adaptation of the ScleroID questionnaire were conducted according to COnsensus-based Standard for the selection of health Measurement INstruments (COSMIN) guidelines. The test-retest reliability was assessed in 50 Danish patients with SSc.Results: All steps for the translation process were followed and approved by the developers of ScleroID. The translation process resulted in changes to the wording of 'aspects' to 'symptoms', 'phenomenon' to 'syndrome', and 'social life' to 'social relations and leisure activities' to create a more meaningful translation in a Danish context. For the Danish version of the ScleroID, the intraclass correlation coefficient (ICC) was 0.90 [95% confidence interval (CI) 0.83; 0.94]. The ICC for each of the 10 individual health domains in ScleroID ranged from 0.52 (95% CI 0.29; 0.70) (digital ulcers) to 0.87 (0.78; 0.92) (lower gastrointestinal symptoms and fatigue).Conclusion: The overall ICC for the Danish version of the ScleroID was excellent, which indicates that it can be implemented as a reliable patient-reported outcome measure in patients with SSc in Denmark.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"1-8"},"PeriodicalIF":2.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A preceptorship programme to learn ultrasonography for diagnosis of giant cell arteritis. 学习超声诊断巨细胞动脉炎的实习计划。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-04-02 DOI: 10.1080/03009742.2025.2480871

C B Mukhtyar, A Ather, G Ducker, T Ecclestone, S Fordham, H Naeem, F L Coath

{"title":"A preceptorship programme to learn ultrasonography for diagnosis of giant cell arteritis.","authors":"C B Mukhtyar, A Ather, G Ducker, T Ecclestone, S Fordham, H Naeem, F L Coath","doi":"10.1080/03009742.2025.2480871","DOIUrl":"https://doi.org/10.1080/03009742.2025.2480871","url":null,"abstract":"Objective: Ultrasonography has been proposed as the initial diagnostic modality in suspected giant cell arteritis. Proposed quality standards advocate for a certified sonographer. Currently, there are no formal training programmes, and single educational events do not suffice as certification. We developed a preceptorship programme for diagnostic ultrasonography. Here, we describe its contents and test its efficacy.Method: The programme comprises three stages. The preclinical stage includes machine setting and surface anatomy. Second stage includes supervised assessment, passed via a directly observed procedure form. In the final validation stage, the trainee and trainer perform an ultrasonography examination in succession, with a comparison of the results. For this programme, a scan included all three segments of the superficial temporal artery and all three parts of the axillary arteries. Comparison of the intima-media thickness (IMT) and categorical judgements for the halo sign and final diagnosis were made.Results: Six trainees have been through this programme so far. A median of 16 ultrasonography examinations was required to reach the validation stage. The mean ± SD IMT in 360 segments, as measured by the trainee and trainer, was 0.45 ± 0.34 and 0.46 ± 0.35, respectively (p = 0.26). The agreement between trainee and trainer for the presence or absence of halo was excellent in 403 segments (κ = 0.91, 95% confidence interval 0.86, 0.96). There was 100% agreement on the final diagnosis.Conclusion: The integration of technical knowledge with practical skills results in a robust training programme, validating trainees to continue scanning independently.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"1-6"},"PeriodicalIF":2.2,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A patient with multiple sclerosis successfully treated with tofacitinib for rheumatoid arthritis. 多发性硬化症患者成功地用托法替尼治疗类风湿关节炎。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-04-01 DOI: 10.1080/03009742.2025.2463733

G T Sakellariou, N Chaitidis, I Katsigianni, I Tsifountoudis, P Vounotrypidis

引用次数: 0

Crowned dens syndrome: a rare yet intriguing condition of the spine. 冠齿综合征：一种罕见但有趣的脊柱疾病。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-03-26 DOI: 10.1080/03009742.2025.2465130

E A Acar, F C Tasgöz, S Uslu, O Soysal Gündüz

引用次数: 0

Evaluation of therapeutic plasma exchange in anti-neutrophil cytoplasmic antibody-associated vasculitis in real-life settings: long-term results of propensity score matching analysis in high-risk patients. 评估现实生活中抗中性粒细胞细胞质抗体相关血管炎的治疗血浆交换：高风险患者倾向评分匹配分析的长期结果

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-03-24 DOI: 10.1080/03009742.2025.2470517

B İnce, M Bektas, Ü A Gülseren, E Ük, B Çelik, S Yüce, S Dadin, H Yazici, Y Yalçinkaya, B Artim-Esen, A Gül, S Kalayoglu-Bes Is Ik, M İnanç

{"title":"Evaluation of therapeutic plasma exchange in anti-neutrophil cytoplasmic antibody-associated vasculitis in real-life settings: long-term results of propensity score matching analysis in high-risk patients.","authors":"B İnce, M Bektas, Ü A Gülseren, E Ük, B Çelik, S Yüce, S Dadin, H Yazici, Y Yalçinkaya, B Artim-Esen, A Gül, S Kalayoglu-Bes Is Ik, M İnanç","doi":"10.1080/03009742.2025.2470517","DOIUrl":"10.1080/03009742.2025.2470517","url":null,"abstract":"Objective: To evaluate the prognostic significance and safety of therapeutic plasma exchange (TPE) in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with severe organ or system involvement.Method: Data of patients diagnosed with AAV between 2011 and 2021 were evaluated retrospectively. Patients with baseline estimated glomerular filtration rate (eGFR) ≤ 50 mL/min/1.73m2 or diffuse alveolar haemorrhage (DAH) were included in the analysis (n = 71). Patients who underwent TPE were compared with others in the groups formed after two models of propensity score matching (PSM). Initial PSM was performed according to the presence of DAH, age, gender, eGFR, and BVAS. A data-driven approach was conducted for the second model.Results: In the initial PSM cohort (n = 48), the remission rate at 6 months was lower in the TPE group (p = 0.04). There were no significant differences in mortality and improvement of eGFR at 6 and 12 months. No severe complications due to TPE were observed. Rates of serious infections (SIs) and end-stage renal disease (ESRD) at 12 months were higher in the TPE group (p = 0.016 and 0.02, respectively). Data-driven PSM analysis (n = 44) revealed no significant differences between groups.Conclusion: We did not demonstrate a positive effect of TPE on remission, ESRD, and mortality in AAV in this study. Despite low short-term complication rates, the increased risk of SIs possibly associated with ESRD was remarkable. The limited long-term benefits of TPE should be carefully weighed against its associated risks when selecting patients for treatment.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"1-10"},"PeriodicalIF":2.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in treatment response in patients with rheumatoid arthritis treated with tumour necrosis factor inhibitor: a cohort study from the DANBIO registry. 类风湿性关节炎患者接受肿瘤坏死因子抑制剂治疗反应的性别差异：来自DANBIO注册的队列研究

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-03-20 DOI: 10.1080/03009742.2025.2471713

K B Lauridsen, K S Duch, A S Mortensen, R Cordtz, S Kristensen, M L Lund, L W Dreyer

{"title":"Sex differences in treatment response in patients with rheumatoid arthritis treated with tumour necrosis factor inhibitor: a cohort study from the DANBIO registry.","authors":"K B Lauridsen, K S Duch, A S Mortensen, R Cordtz, S Kristensen, M L Lund, L W Dreyer","doi":"10.1080/03009742.2025.2471713","DOIUrl":"https://doi.org/10.1080/03009742.2025.2471713","url":null,"abstract":"Objective: The aim of this study was to investigate associations between sex and treatment response and persistence in patients with rheumatoid arthritis (RA) initiating their first tumour necrosis factor inhibitor (TNFi).Method: This Danish nationwide cohort study included RA-patients starting their first TNFi treatment between 2006 and 2022. Overall and age-specific treatment response was compared across sexes at 4 and 12 months. Treatment persistence was investigated using survival analysis.Results: In total, 7789 RA-patients were identified; 75% were females. Females had slightly smaller ∆DAS28-CRP compared to males after 12 months, mainly due to less reduction of swollen joint count (SJC) and CRP. At 12 months the crude proportion of males with good response was higher (62%) than in females (55%), adjusted RR 1.14 (95% confidence interval (CI) 1.06; 1.23). The adjusted hazard ratio for treatment termination within first year was 0.82 (95% CI 0.73; 0.92) in males versus females. The median treatment persistence for individuals aged <50 years was 1.6 years (95% CI 1.4; 1.8) in females and 3.2 years (95% CI 2.6; 4.0) in males. The same difference was not seen in patients aged > 50 years.Conclusion: Despite similar baseline disease activity, females had a lower chance than males of achieving good response 4 and 12 months after starting treatment with first TNFi. The sex difference in DAS28-CRP improvement is caused by a greater decrease in CRP and SJC among males. Further, females had an increased risk of discontinuation, especially among patients aged < 50 years.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"1-11"},"PeriodicalIF":2.2,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiovascular risk and cardiac involvement in idiopathic inflammatory myopathies: insights from a cross-sectional Swedish single-centre study. 特发性炎症性肌病的心血管风险和心脏受累情况：瑞典单中心横断面研究的启示。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-03-13 DOI: 10.1080/03009742.2025.2470011

B Hanna, C L Polte, E Sakiniene, J von Brömsen, E Bollano, R Pullerits, T Jin

{"title":"Cardiovascular risk and cardiac involvement in idiopathic inflammatory myopathies: insights from a cross-sectional Swedish single-centre study.","authors":"B Hanna, C L Polte, E Sakiniene, J von Brömsen, E Bollano, R Pullerits, T Jin","doi":"10.1080/03009742.2025.2470011","DOIUrl":"https://doi.org/10.1080/03009742.2025.2470011","url":null,"abstract":"Objective: We aimed to investigate the cardiovascular profile, including risk factors and cardiovascular abnormalities, in patients with idiopathic inflammatory myopathies (IIMs).Method: In this cross-sectional study, 109 IIM patients and 20 age- and gender-matched healthy controls were enrolled and underwent electrocardiographic and transthoracic echocardiographic examinations. We analysed blood levels of cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP), assessed IIM disease-specific features, and evaluated the medical history of cardiovascular risk factors. IIM patients were stratified into two groups: those with previous cardiac involvement and those without.Results: IIM patients had a higher body mass index (BMI) and a greater prevalence of diabetes mellitus and dyslipidaemia than healthy controls (p = 0.023, p = 0.024, and p = 0.042, respectively). They also showed significantly higher rates of arrhythmia, cardiac axis deviation, negative T-waves, and suspected pulmonary hypertension, along with elevated NT-proBNP levels (p = 0.041, p = 0.004, p = 0.041, p = 0.012, and p = 0.034, respectively). A significantly higher proportion (p = 0.037) of immune-mediated necrotizing myopathy (IMNM) subtype (50%) was found among IIM with previous cardiac involvement compared to those without (20%). cTnI levels were significantly higher in IIM with cardiac involvement than in IIM without cardiac involvement (p = 0.009).Conclusions: Cardiovascular complications in patients with IIM may result from an increased prevalence of traditional cardiovascular risk factors, such as higher BMI, diabetes mellitus, and dyslipidaemia, and/or from direct cardiac involvement, such as previous myocarditis. Cardiac involvement in IIM is notably associated with the IMNM subtype.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"1-10"},"PeriodicalIF":2.2,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare and striking case of capillary leak syndrome. 一例罕见而引人注目的毛细血管渗漏综合征。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2025-03-12 DOI: 10.1080/03009742.2025.2471717

S Gülle, D Şanlı

引用次数: 0