Scandinavian Journal of Rheumatology最新文献_第10页

Treatment with a tissue-selective oestrogen complex does not affect disease pathology but reduces pre-BI cells in lupus-prone mice. 用组织选择性雌激素复合物治疗不会影响疾病病理，但会减少易患狼疮的小鼠的BI前细胞。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2024-01-01 Epub Date: 2023-12-28 DOI: 10.1080/03009742.2023.2251753

C Drevinge, J M Scheffler, J Nordqvist, C Engdahl, H Carlsten, U Islander

{"title":"Treatment with a tissue-selective oestrogen complex does not affect disease pathology but reduces pre-BI cells in lupus-prone mice.","authors":"C Drevinge, J M Scheffler, J Nordqvist, C Engdahl, H Carlsten, U Islander","doi":"10.1080/03009742.2023.2251753","DOIUrl":"10.1080/03009742.2023.2251753","url":null,"abstract":"Objective: Systemic lupus erythematosus (SLE or lupus) is an autoimmune disease characterized by B-cell dysfunction, production of autoantibodies, and immune complex formation. Lupus is overrepresented in females, indicating that sex hormones play a role in the pathophysiology. Treatment with a tissue-selective oestrogen complex (TSEC) containing conjugated oestrogens and the selective oestrogen receptor modulator bazedoxifene (BZA) protects against postmenopausal vasomotor symptoms and osteoporosis, but its impact on organ damage in lupus is not fully understood.Method: We used ovariectomized MRL/lpr mice, treated with two different physiological doses of 17β-oestradiol-3-benzoate (E2), BZA, or TSEC (E2 plus BZA), to assess early and late B-cell development and to determine histological disease manifestations in the kidneys and salivary glands.Results: TSEC treatment reduced the frequency of the pre-BI population in bone marrow to levels equivalent to treatment with physiological doses of E2 alone but did not affect any of the other examined B-cell populations. Our earlier studies indicated that TSEC treatment did not aggravate disease development in ovariectomized MRL/lpr mice, while protecting against trabecular bone loss. Here, we follow up on our previous study and show that neither ovariectomy alone nor TSEC treatment of ovariectomized MRL/lpr mice influenced perivascular lymphocyte infiltration to the kidneys or salivary glands.Conclusion: TSEC does not aggravate a mouse model of lupus, when given in doses that protect against postmenopausal lupus-associated bone loss. This indicates that further investigations into TSEC as a treatment for osteoporosis or vasomotor symptoms in postmenopausal women with SLE are warranted.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"49-58"},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10311567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity of the Brief Illness Perception Questionnaire in people with knee pain: a Rasch analysis. 简短疾病感知问卷在膝关节疼痛患者中的有效性：Rasch分析。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2024-01-01 Epub Date: 2023-12-28 DOI: 10.1080/03009742.2023.2256089

E Ginnerup-Nielsen, E Bandak, C Bartholdy, M Henriksen, E E Wæhrens

{"title":"Validity of the Brief Illness Perception Questionnaire in people with knee pain: a Rasch analysis.","authors":"E Ginnerup-Nielsen, E Bandak, C Bartholdy, M Henriksen, E E Wæhrens","doi":"10.1080/03009742.2023.2256089","DOIUrl":"10.1080/03009742.2023.2256089","url":null,"abstract":"Objective: The Brief Illness Perception Questionnaire (B-IPQ) is a frequently used measure of illness perception (IP). The aim of this study was to explore the psychometric properties of the questionnaire when used in elderly people with knee pain.Method: Based on data from the Frederiksberg Cohort on elderly people reporting knee pain (N = 836), the psychometric properties of the eight B-IPQ items (1 'Consequences', 2 'Timeline', 3 'Personal control', 4 'Treatment control', 5 'Identity', 6 'Concern', 7 'Coherence', and 8 'Emotions') were analysed using Rasch analysis to establish whether the questionnaire provides reliable and valid measures of IP.Results: Threshold disordering was found on the 1-10 rating scale in all items. When rescaling to a 0-2 rating scale, disordering was resolved in six items. Item goodness-of-fit analyses revealed that two items displayed underfit misfit and four items overfit misfit; hence, the B-IPQ does not present unidimensionality. The person separation index indicated that items separate respondents into only two IP levels. Finally, floor and ceiling effects were found, indicating that the B-IPQ may not fully describe the extent of IP in this population.Conclusion: The 1-10 rating scale used in the Danish B-IPQ targeting knee pain is suboptimal, while a 0-2 scale improves the psychometric properties of the scale. The B-IPQ does not present unidimensionality and the use of a sum score is therefore not recommended when assessing IP. The B-IPQ may not cover the extent of IP in elderly people with knee pain.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"63-71"},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41133107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed identification of disseminated infection in a patient with rheumatoid arthritis and septic arthritis: a case report. 类风湿性关节炎合并脓毒性关节炎患者播散性感染的延迟识别：病例报告。

IF 2.2 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2024-01-01 Epub Date: 2023-12-28 DOI: 10.1080/03009742.2023.2266909

S S Røgind, M L Hetland

引用次数: 0

Reviewer acknowledgement December 2022 – November 2023 审稿人确认 2022 年 12 月 - 2023 年 11 月

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-12-28 DOI: 10.1080/03009742.2024.2295652

引用次数: 0

Reduced sleep quality is highly prevalent and associated with physical function and cardiorespiratory fitness in patients with axial spondyloarthritis: a cross-sectional study 轴性脊柱关节炎患者普遍存在睡眠质量下降问题，且睡眠质量下降与身体功能和心肺功能相关：一项横断面研究

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-12-14 DOI: 10.1080/03009742.2023.2281069

C Fongen, H Dagfinrud, A Bilberg, SH Sveaas

引用次数: 0

Unravelling the complexity: polymyositis, systemic sclerosis, ulcerative colitis, and papillary thyroid carcinoma 揭开复杂的面纱：多发性肌炎、系统性硬化症、溃疡性结肠炎和甲状腺乳头状癌

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-12-13 DOI: 10.1080/03009742.2023.2288775

S Ösken

引用次数: 0

Identical twins with statin-associated anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibody-positive autoimmune myopathy 同卵双胞胎患有他汀类药物相关的抗-3-羟基-3-甲基戊二酰辅酶 A 还原酶自身抗体阳性自身免疫性肌病

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-12-13 DOI: 10.1080/03009742.2023.2289729

M Mali, L Pirilä, L Perander, M Gardberg, M Jokela

引用次数: 0

Massive abdominal haemorrhage due to sequential omental vasculitis and ruptured aneurysms in a patient with granulomatosis with polyangiitis 一名肉芽肿伴多血管炎患者因相继发生网膜血管炎和动脉瘤破裂而导致腹部大出血

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-12-12 DOI: 10.1080/03009742.2023.2286118

M Guerini, D Sorace, F Bobbio Pallavicini, V Codullo, M Lucioni, S Fraticelli, J Viganò, P Quaretti, P Delvino

引用次数: 0

Clinical and ultrasound features of difficult-to-treat rheumatoid arthritis: A multicenter RA ultrasound cohort study 难以治疗的类风湿关节炎的临床和超声特征：一项多中心类风湿关节炎超声队列研究

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-12-12 DOI: 10.1080/03009742.2023.2277542

T Michitsuji, S Fukui, S Morimoto, Y Endo, A Nishino, S Nishihata, Y Tsuji, T Shimizu, M Umeda, R Sumiyoshi, T Koga, N Iwamoto, T Origuchi, Y Ueki, T Yoshitama, N Eiraku, N Matsuoka, A Okada, K Fujikawa, H Ohtsubo, H Takaoka, H Hamada, T Tsuru, M Nawata, Y Arinobu, T Hidaka, Y Tada, A Kawakami, S-Y Kawashiri

引用次数: 0

Evaluation of an individually tailored smoking-cessation intervention for patients with rheumatoid arthritis in an outpatient clinic. 对门诊类风湿关节炎患者个体化戒烟干预的评价。

IF 2.1 4区医学

Scandinavian Journal of Rheumatology Pub Date : 2023-11-01 Epub Date: 2023-02-23 DOI: 10.1080/03009742.2023.2172903

M-L Karlsson, K Hertzberg-Nyquist, S Saevarsdottir, I E Lundberg, I Demmelmaier, S Pettersson, K Chatzidionysiou

{"title":"Evaluation of an individually tailored smoking-cessation intervention for patients with rheumatoid arthritis in an outpatient clinic.","authors":"M-L Karlsson, K Hertzberg-Nyquist, S Saevarsdottir, I E Lundberg, I Demmelmaier, S Pettersson, K Chatzidionysiou","doi":"10.1080/03009742.2023.2172903","DOIUrl":"10.1080/03009742.2023.2172903","url":null,"abstract":"Objective: The aim of this study was to evaluate an individually tailored smoking-cessation intervention delivered in rheumatology care and compare the characteristics of patients who quit smoking with those who did not.Method: This was an open single-group prospective intervention study over 24 months, with assessments at baseline and at 6, 12, 18, and 24 months. Current smokers with rheumatoid arthritis (RA) were invited to a smoking-cessation programme including behavioural change support, with or without pharmacotherapy. Data on disease activity, medical treatment, and patient-reported outcomes were retrieved from the Swedish Rheumatology Quality Register. The primary outcome was the proportion of patients at month 24 who reported having quit smoking with self-reported 7 day smoking abstinence.Results: In total, 99 patients participated in the study. Median age was 58 years (interquartile range 50-64); 69% were female and 88% rheumatoid factor and/or anti-cyclic citrullinated peptide positive. At 24 months, 21% of the patients had quit smoking. At 6, 12, and 18 months, 12%, 12%, and 14% of patients, respectively, had quit smoking. For patients still smoking at 24 months, the median number of cigarettes per day was significantly reduced from 12 to 6 (p ≤ 0.001). Among patients who had quit smoking at 24 months, a smaller proportion reported anxiety at baseline compared to those still smoking (28% vs 58%, p = 0.02).Conclusion: A smoking-cessation intervention including behavioural change support with or without pharmacotherapy can be helpful for a substantial number of RA patients. Anxiety is associated with lower smoking-cessation success rates.","PeriodicalId":21424,"journal":{"name":"Scandinavian Journal of Rheumatology","volume":" ","pages":"591-600"},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10816843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0