SAGE Open Medical Case Reports最新文献_第4页

Severe left main coronary artery disease and STEMI in a 19-year-old without traditional risk factors: A rare case of premature coronary artery disease.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251321041

Wasef Alhroub, Maaweya Jabareen, Haya Abu-Mayyaleh, Bayyena Abu-Radwan, Mustafa Shehadeh, Ali Abu-Farah, Talha Isayed

{"title":"Severe left main coronary artery disease and STEMI in a 19-year-old without traditional risk factors: A rare case of premature coronary artery disease.","authors":"Wasef Alhroub, Maaweya Jabareen, Haya Abu-Mayyaleh, Bayyena Abu-Radwan, Mustafa Shehadeh, Ali Abu-Farah, Talha Isayed","doi":"10.1177/2050313X251321041","DOIUrl":"10.1177/2050313X251321041","url":null,"abstract":"Premature coronary artery disease (CAD) is defined by the early onset of significant atherosclerotic narrowing of the coronary arteries, generally occurring before age 55 in men and 60 in women. This condition is an increasing concern in cardiovascular medicine due to its impact on younger populations, resulting in greater morbidity, diminished quality of life, and a substantial economic burden. Common risk factors include dyslipidemia, hypertension, diabetes, smoking, obesity, and genetic predispositions such as familial hyperlipidemia. This case report describes a 19-year-old male with no known cardiovascular risk factors who presented with an ST-segment elevation myocardial infarction and ventricular tachycardia caused by left main coronary artery disease including the left anterior descending artery and the left circumflex artery. Despite lacking common risk factors, he underwent successful coronary artery bypass grafting with two grafts.","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251321041"},"PeriodicalIF":0.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IL-23 blockade in a patient with psoriasis and Toxoplasma gondii reactivation history: Case report and review.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251320196

J Dagher, J Ringuet

引用次数: 0

A rare epidermal growth factor receptor T790M/cis-C797S/L718Q compound mutation in a lung adenocarcinoma patient who did not derive any benefit from combination therapy with afatinib and bevacizumab.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251319381

Xiaopeng Meng, Jingyi Liu, Xiaohui Wu, Pei Peng

{"title":"A rare epidermal growth factor receptor T790M/cis-C797S/L718Q compound mutation in a lung adenocarcinoma patient who did not derive any benefit from combination therapy with afatinib and bevacizumab.","authors":"Xiaopeng Meng, Jingyi Liu, Xiaohui Wu, Pei Peng","doi":"10.1177/2050313X251319381","DOIUrl":"10.1177/2050313X251319381","url":null,"abstract":"The most common mutations in epidermal growth factor receptor (EGFR) are exon 19 deletions and exon 21 L858R mutations, both of which respond effectively to EGFR tyrosine kinase inhibitors. However, the efficacy of EGFR tyrosine kinase inhibitors against rare EGFR mutations remains controversial. Many patients eventually develop resistance to EGFR tyrosine kinase inhibitors. Here, we encountered the case of a 62-year-old male with lung adenocarcinoma and a history of hypertension, who harbored a rare EGFR L858R/T790M/cis-C797S/L718Q compound mutation and showed resistance to osimertinib. The patient showed a partial response to treatment with a combination of afatinib and bevacizumab lasting 2 months. Although this case did not demonstrate a clear benefit from dual therapy with afatinib and bevacizumab, it provides a valuable therapeutic reference for patients with rare compound EGFR mutations and offers insights for future studies.","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251319381"},"PeriodicalIF":0.6,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An uncommon presentation of discoid lupus suggesting systemic evolution.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251320480

Ariana Nateghi, Julie Desrochers

引用次数: 0

Primary low-grade endometrial stromal sarcoma of the ovary with mesenteric metastasis: An unusual case report.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251321044

Jun Yuan, Yajun Fu, Xiaohong Jiang, Na Li

{"title":"Primary low-grade endometrial stromal sarcoma of the ovary with mesenteric metastasis: An unusual case report.","authors":"Jun Yuan, Yajun Fu, Xiaohong Jiang, Na Li","doi":"10.1177/2050313X251321044","DOIUrl":"10.1177/2050313X251321044","url":null,"abstract":"Low-grade endometrial stromal sarcoma (LGESS) accounts for only 0.2% of gynecological malignancies. Primary low-grade extrauterine endometrial stromal sarcoma (LGEESS) is rare, and its morphology varies according to the tumor's location, posing a significant diagnostic challenge for clinical pathologists. A 46-year-old female patient with bilateral ovarian cysts and multiple uterine fibroids underwent ovarian cystectomy and uterine myomectomy in 2013. Color Doppler ultrasound showed multiple uterine fibroids and bilateral ovarian cysts (left: 74 × 74 × 64 mm, right: 26 × 22 mm). Laboratory tests indicated an elevated squamous cell carcinoma associated antigen. The patient subsequently underwent a total hysterectomy and bilateral salpingo-oophorectomy. Intraoperative pathological results were diagnosed as benign ovarian cysts. Combined with the morphological, immunohistochemical, and molecular results from the paraffin section, LGEESS was determined to be the final diagnosis. We prepared a comprehensive case report on the clinicopathological features of LGEESS to provide clinical pathologists with references that can help avoid misdiagnosis or missed diagnoses.","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251321044"},"PeriodicalIF":0.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11829283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early disseminated cutaneous Lyme disease with SIADH, transaminitis, and pancytopenia: A case report.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251320186

Louis Deschênes, Philippe Jutras, Janie Bujold

引用次数: 0

Recalcitrant vulvar lichen planus cleared on abrocitinib: A case report.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251320469

Celina DeBiasio, Carly Kirshen

引用次数: 0

Cerebral hypoperfusion due to rapid blood pressure control in a patient with type B aortic dissection: A case report.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251316985

Yikun Zhao, Heng Li, Yuanyuan Guo

{"title":"Cerebral hypoperfusion due to rapid blood pressure control in a patient with type B aortic dissection: A case report.","authors":"Yikun Zhao, Heng Li, Yuanyuan Guo","doi":"10.1177/2050313X251316985","DOIUrl":"10.1177/2050313X251316985","url":null,"abstract":"Type B aortic dissection represents a life-threatening cardiovascular event, necessitating a comprehensive treatment approach that includes anti-impulse therapy for blood pressure and heart rate control, movement restriction, analgesia, sedation, and consideration of subsequent endovascular or open surgery. Management of acute aortic dissection involves stringent blood pressure control to prevent extension of the dissection, which is critical in both surgical preparation and conservative treatment strategies. While the treatment regimen is relatively well-established, and early and long-term follow-up results are promising, there have been reports of adverse events during treatment. In this context, we present a case of a 40-year-old male with acute type B aortic dissection who developed cerebral hypoperfusion as a consequence of rapid blood pressure reduction, underscoring the need for balanced hemodynamic management. Following thoracic endovascular aortic repair surgery and hyperbaric oxygen therapy, the patient fully recovered 6 months later with no lingering sequelae. While current guidelines emphasize specific numerical values for blood pressure control in type B aortic dissection, the case underscores the potential need for a more individualized approach tailored to the unique characteristics of each patient.","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251316985"},"PeriodicalIF":0.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the surface: A case study about nevus sebaceous removal for cosmetic concerns.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X251317802

Joshua Lewis, Jatinder P Singh, Ernst J Nicanord

{"title":"Beyond the surface: A case study about nevus sebaceous removal for cosmetic concerns.","authors":"Joshua Lewis, Jatinder P Singh, Ernst J Nicanord","doi":"10.1177/2050313X251317802","DOIUrl":"10.1177/2050313X251317802","url":null,"abstract":"Nevus sebaceous, a benign scalp birthmark, typically presents without immediate health concerns but may require removal as it becomes bothersome with age. Symptoms are typically cosmetic, lacking pain or bleeding. Clinical presentation varies with age, initially appearing as a smooth, hairless yellowish patch, later evolving into an elevated lesion after the onset of puberty. We report a case of a 25-year-old female with nevus sebaceous. Despite its benign nature, the patient opted for excision due to cosmetic concerns and the potential for malignancy. Surgical removal was successful without complications. This case underscores the importance of early diagnosis and intervention to alleviate discomfort and potential malignancy. While rare, malignant transformation can occur, emphasizing the need for vigilant monitoring and timely surgical intervention, particularly during pre-puberty stages. Treatment should prioritize removal to prevent malignant progression and address cosmetic concerns. Further research is needed to refine management strategies for nevus sebaceous.","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251317802"},"PeriodicalIF":0.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eosinophilic gastroenteritis without identifiable allergens in an adult: A case report.

IF 0.6

SAGE Open Medical Case Reports Pub Date : 2025-02-03 eCollection Date: 2025-01-01 DOI: 10.1177/2050313X241312935

Haisheng Lan, Tishang Yang, Li Zhou, Jiansheng Lv, Xvsen Huang

引用次数: 0