Malignant myoepithelial tumor of the right fibula in a young female: A case report.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

SAGE Open Medical Case Reports Pub Date : 2025-05-24 eCollection Date: 2025-01-01 DOI:10.1177/2050313X251342989

Tasneem AbuShaikha, Saja Alzboun, Ameer Alhosheyeh, Imad Aljaafreh, Ahmad Alhalabia, Haytham Shaban, Ahmed Barbarawi, Yazan Haddar, Farah Awad, Elias Edward Lahham

{"title":"Malignant myoepithelial tumor of the right fibula in a young female: A case report.","authors":"Tasneem AbuShaikha, Saja Alzboun, Ameer Alhosheyeh, Imad Aljaafreh, Ahmad Alhalabia, Haytham Shaban, Ahmed Barbarawi, Yazan Haddar, Farah Awad, Elias Edward Lahham","doi":"10.1177/2050313X251342989","DOIUrl":null,"url":null,"abstract":"<p><p>Myoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment, she developed uncontrolled leg pain and metastatic disease to the lungs, leading to a palliative above-knee amputation. Due to the rarity of malignant myoepithelial tumors and the lack of treatment guidelines, a systematic literature review was conducted, exploring various chemotherapeutic and biological agents. Her treatment was planned by a multidisciplinary team, considering her willingness to continue treatment, and ultimately, a decision was made to proceed with palliative care. This case report aims to provide valuable insights for physicians managing patients with this rare diagnosis.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251342989"},"PeriodicalIF":0.6000,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12104591/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SAGE Open Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/2050313X251342989","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Myoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment, she developed uncontrolled leg pain and metastatic disease to the lungs, leading to a palliative above-knee amputation. Due to the rarity of malignant myoepithelial tumors and the lack of treatment guidelines, a systematic literature review was conducted, exploring various chemotherapeutic and biological agents. Her treatment was planned by a multidisciplinary team, considering her willingness to continue treatment, and ultimately, a decision was made to proceed with palliative care. This case report aims to provide valuable insights for physicians managing patients with this rare diagnosis.

查看原文本刊更多论文

年轻女性右腓骨恶性肌上皮肿瘤1例报告。

肌上皮性肿瘤是一种极为罕见的肿瘤，迄今文献报道仅30例左右。我们报告一位27岁女性被诊断为恶性右腓骨肌上皮肿瘤/肌上皮癌，最初接受全身化疗。在治疗期间，她出现了无法控制的腿部疼痛和转移到肺部的疾病，导致姑息性膝上截肢。由于恶性肌上皮肿瘤的罕见性和治疗指南的缺乏，我们进行了系统的文献综述，探索各种化疗和生物制剂。考虑到她继续治疗的意愿，一个多学科团队计划了她的治疗，最终，决定继续进行姑息治疗。本病例报告旨在为医生管理这种罕见诊断的患者提供有价值的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

SAGE Open Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.60

自引率

0.00%

发文量

320

审稿时长

8 weeks

期刊介绍： SAGE Open Medical Case Reports (indexed in PubMed Central) is a peer reviewed, open access journal. It aims to provide a publication home for short case reports and case series, which often do not find a place in traditional primary research journals, but provide key insights into real medical cases that are essential for physicians, and may ultimately help to improve patient outcomes. SAGE Open Medical Case Reports does not limit content due to page budgets or thematic significance. Papers are subject to rigorous peer review and are selected on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, SAGE Open Medical Case Reports facilitates the discovery of the connections between papers, whether within or between disciplines. Case reports can span the full spectrum of medicine across the health sciences in the broadest sense, including: Allergy/Immunology Anaesthesia/Pain Cardiovascular Critical Care/ Emergency Medicine Dentistry Dermatology Diabetes/Endocrinology Epidemiology/Public Health Gastroenterology/Hepatology Geriatrics/Gerontology Haematology Infectious Diseases Mental Health/Psychiatry Nephrology Neurology Nursing Obstetrics/Gynaecology Oncology Ophthalmology Orthopaedics/Rehabilitation/Occupational Therapy Otolaryngology Palliative Medicine Pathology Pharmacoeconomics/health economics Pharmacoepidemiology/Drug safety Psychopharmacology Radiology Respiratory Medicine Rheumatology/ Clinical Immunology Sports Medicine Surgery Toxicology Urology Women''s Health.