SAGE Open Medical Case Reports最新文献

{"title":"Case report and review of an unusual congenital follicular melanocytic nevus in a child.","authors":"Moolla Siddiq, Liy-Wong Carmen","doi":"10.1177/2050313X251350364","DOIUrl":"10.1177/2050313X251350364","url":null,"abstract":"<p><p>We present a case of a 7-year-old girl with a congenital melanocytic nevus exhibiting a unique follicular pigmentation pattern. The lesion was present since birth and was largely asymptomatic. Regular dermatological follow-ups and patient education on self-screening and sun protection were recommended. This case highlights the wide-ranging morphological appearance of congenital melanocytic nevus and underscores the recommendations of monitoring for potential malignancy and addressing psychosocial impacts.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251350364"},"PeriodicalIF":0.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum uterine atony complicating labor in a patient with systemic lupus erythematosus: A case report.","authors":"Amadea Ivana Hartanto, Amillia Siddiq, Ferdy Ferdian, Ruswana Anwar, Hanom Husni Syam, Birgitta Maria Dewayani","doi":"10.1177/2050313X251344026","DOIUrl":"10.1177/2050313X251344026","url":null,"abstract":"<p><p>Systemic lupus erythematosus predominantly affects women of all ages, particularly targeting those of reproductive age, and can increase the risk of adverse pregnancy outcomes, including uterine atony, which is rarely documented. This case report examines uterine atony in a systemic lupus erythematosus patient and its microscopic features. A 37-year-old woman with systemic lupus erythematosus, in her fourth pregnancy, experienced vaginal bleeding, and severe hypotension after delivering at 32-33 weeks. Despite treatments including fluids, oxytocin, misoprostol, and methylergometrine, uterine contractions did not improve, leading to a supravaginal hysterectomy. Histopathology revealed hypertrophic myocytes and extensive fibrosis. This case suggests that systemic lupus erythematosus may increase the risk of uterine atony and postpartum hemorrhage due to uterine fibrosis and reduced response to uterotonics.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251344026"},"PeriodicalIF":0.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of high grade pancreatic neuroendocrine tumor and the importance of endoscopic ultrasound-guided fine needle biopsy technique.","authors":"Shrey Dalwadi, Zehara Abidi, Avneet Singh, Alexander Garcia, Punitha Shivaprasad, Kunal Dalal","doi":"10.1177/2050313X251347424","DOIUrl":"10.1177/2050313X251347424","url":null,"abstract":"<p><p>Pancreatic neuroendocrine tumors are an uncommon group of insidious neoplasms that are often diagnosed in the advanced stages. Diagnosing pancreatic neuroendocrine tumors involves proper biopsy technique and immunohistochemistry, while treatments include targeted therapies and systemic chemotherapy. When diagnosed early, patients with localized disease generally have a positive prognosis. We share a case of a 56-year-old man presenting to the emergency department with acute abdominal pain found to have poorly differentiated pancreatic neuroendocrine tumor with metastasis on repeat endoscopic ultrasound-guided fine needle biopsy. Despite multiple treatment changes, sustained tumor presence led to numerous complications and ultimately patient death. This case highlights the nuances and challenges of diagnosing and treating a rare pancreatic neuroendocrine tumor, such as the importance of biopsy technique.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251347424"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iatrogenic vascular trauma of the extremities in pediatric patients: A case series report and review of literature.","authors":"Javad Salimi, Amirali Ahrabi","doi":"10.1177/2050313X251347827","DOIUrl":"10.1177/2050313X251347827","url":null,"abstract":"<p><p>Available data regarding iatrogenic vascular trauma in the pediatric population mainly comprise case reports and series, with management protocols not firmly established. This study aims to report seven pediatric cases of iatrogenic vascular trauma in the extremities, presenting as arteriovenous fistula and pseudoaneurysm, along with their surgical management. We further reviewed the literature and discussed other possible management approaches for arteriovenous fistula and pseudoaneurysm in this specific population. We reviewed the cases of seven pediatric patients (six male and one female) with iatrogenic vascular trauma presenting as arteriovenous fistula and pseudoaneurysm in their extremities. Four patients (57%) were admitted to the intensive care unit due to their severe medical condition before developing these complications. Arterial injury during venous access accounted for five cases (71%). Two patients developed arteriovenous fistula after cardiac catheterization through the common femoral artery for their underlying tetralogy of Fallot. All patients underwent surgical repair. While arteriovenous fistula and pseudoaneurysm are infrequent, their occurrence is on the rise, primarily due to the more frequent use of venous access and catheterization procedures. Surgical approaches include ligation and lateral arteriorrhaphy/venorrhaphy, or resection with arterial end-to-end anastomosis. Despite the growing preference for endovascular treatment in the adult population, such as stent placement or coil embolization, pediatric patients require meticulous attention to the possible risk of stent migration, chronic ischemia, and radiation exposure. Based on our experience, surgical management has generally provided a satisfactory treatment response and recovery. However, this needs to be further evaluated in larger, prospective studies.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251347827"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe transient neonatal hyperinsulinism: First Peruvian case series.","authors":"Manuel André Virú-Loza, Francesca Bermudez-Paredes, Isabel Milagros Arauco-Carhuas","doi":"10.1177/2050313X251347787","DOIUrl":"10.1177/2050313X251347787","url":null,"abstract":"<p><p>Congenital hyperinsulinism is characterized by dysregulated insulin secretion and is the most common and severe cause of persistent hypoglycemia in pediatrics. Brain damage rates can be as high as 50% due to inadequate treatment. Transient congenital hyperinsulinism is more frequent than permanent congenital hyperinsulinism. Acquired hyperinsulinism due to perinatal stress is often transient, too. Diazoxide is the first-line therapy. However, in Peru, reports about pediatric patients with hyperinsulinism treated with diazoxide are scarce. Our article describes the first Peruvian case series of severe transient neonatal hyperinsulinism treated with diazoxide, with good response and manageable adverse effects. Diazoxide should be included in the Single National Pharmaceutical Request Form for Essential Medicines of Peru to expedite the use of a medication as essential as this one.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251347787"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report.","authors":"Ghassan Barnawi, Sarah Kashkari, Arieh Gomolin, May Chergui, Badia Issa-Chergui, Lisa Iannatone","doi":"10.1177/2050313X251341563","DOIUrl":"10.1177/2050313X251341563","url":null,"abstract":"<p><p>This case report describes a 61-year-old female who developed cutaneous small vessel vasculitis following a calcium-hydroxyapatite-based filler injection. The patient presented with a generalized purpuric and petechial rash, along with arthralgia. A skin biopsy confirmed features consistent with cutaneous small vessel vasculitis. Treatment with a 6-week prednisone taper resulted in complete symptom resolution. This observation warrants further investigation into the potential role of dermal fillers in triggering inflammatory conditions like cutaneous small vessel vasculitis.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251341563"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The sequential therapy for non-infectious scleritis: A case report.","authors":"Xiaoxiang Xie, Pan Jiang, Xuxu Li, Jinli Ru","doi":"10.1177/2050313X251346047","DOIUrl":"10.1177/2050313X251346047","url":null,"abstract":"<p><p>Scleritis results from an inflammatory response in the sclera and can be associated with a variety of infectious and non-infectious ocular and systemic diseases. It can cause vision loss, uveitis, high intraocular pressure and other complications, resulting in poor prognosis. There are no reports of non-infectious scleritis in children. Herein, we describe a case of sequential tocilizumab treatment on tofacitinib in a child with non-infectious scleritis. Extensive examinations ruled out the cause of infection, and the previous conventional glucocorticoid treatment was effective, but the disease recurred during drug reduction. Tocilizumab and tofacitinib successfully cured the patient, glucocorticoids were stopped, and all drugs were stopped 2 years later. This report provides a new diagnosis and treatment method for clinicians.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251346047"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitral and tricuspid valve repair in an operated case of complete atrioventricular septal defect: A surgical challenge case report!","authors":"Dhanesh Kumar, Amit Chandra, Naresh Trehan, Shital Prakash, Yatin Mehta, Manisha Mishra, Surinder Bazaz, Sanjeev Chandna","doi":"10.1177/2050313X251346855","DOIUrl":"10.1177/2050313X251346855","url":null,"abstract":"<p><p>Atrioventricular canal defects constitute about 3%-5% of total congenital heart defects, with a prevalence of 0.3-0.4/1000 live births. Mitral valve defects are associated with atrioventricular canal (septal) defects in most cases. Our case is of a 37-year-old male who underwent double patch closure of atrial and ventricular septal defects at the age of 24 years, now presenting with NYHA-III symptoms of severe mitral regurgitation and severe tricuspid regurgitation. The mitral valve was of atrio-ventricular canal type. We repaired both mitral and tricuspid valves using soft rings. Because of a deformed annulus, a soft ring was preferred.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251346855"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary rehabilitation for functional neurological disorder using psychobehavioral approaches in acute inpatient setting: A case report.","authors":"YuanDian Zheng, Taesung Kim, Yoshiki Takeyama, Etienne B Rossert, Yu Jen Lai","doi":"10.1177/2050313X251348413","DOIUrl":"10.1177/2050313X251348413","url":null,"abstract":"<p><p>The role of acute inpatient rehabilitation is pivotal in the treatment of functional neurological disorders, offering a multidisciplinary approach to a condition often challenging to diagnose and manage. This case report discusses a 44-year-old right-handed male with complex past medical histories of Bell's palsy, cholesteatomas, hearing impairment, coronary artery disease, cavernoma, hypertriglyceridemia, glaucoma, hypertension, hyperlipidemia, parotitis, psoriasis, seizure, and tremors transferred to our rehabilitation service with presented functional neurological disorder symptoms. The patient's treatment emphasized an acute comprehensive rehabilitative intervention with psychobehavioral approaches, focusing on both physical symptoms and psychological aspects of the condition. This case illustrates the effectiveness of acute rehabilitative care in functional neurological disorders, highlighting the significance of early intervention and a holistic treatment approach in improving prognosis and overall quality of life for patients with functional neurological disorders.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251348413"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor induced syncope after cerebral infarction: A case report and literature review.","authors":"Zihan Zhao, Ranran Wang, Lihua Gao, Meijing Zhang","doi":"10.1177/2050313X251342060","DOIUrl":"10.1177/2050313X251342060","url":null,"abstract":"<p><p>Cardio-cerebral syndrome refers to cardiac injury following cranial brain injury, representing a critical complication of stroke associated with high morbidity and mortality. Although exercise treadmill testing is widely utilized for myocardial ischemia evaluation, its role in unmasking neurogenic syncope or cardio-cerebral interactions remains under investigation. Existing literature emphasizes that only a small proportion of post-stroke syncope cases undergo comprehensive assessment for combined cerebrovascular-cardiac etiologies, particularly evident in slow-type arrhythmia cases frequently misattributed solely to vasovagal syncope despite potential contributions from brainstem injury or autonomic dysregulation. While most reported post-exercise syncope cases attribute symptoms to vasovagal syncope or common etiologies, underlying cardiovascular/cerebrovascular pathologies are often overlooked, with limited discussion on post-exercise arrhythmia-cerebrovascular disease associations. This report details a unique case of exercise treadmill testing-induced syncope characterized by Brady arrhythmic electrocardiographic changes. Syncope evaluation revealed a newly diagnosed pontine infarction, while cardiac workup excluded structural heart disease, coronary artery stenosis, and Brugada syndrome, underscoring the differential diagnosis challenge between neurogenic and cardiogenic syncope. This case uniquely demonstrates the mechanistic overlap between vasovagal syncope and cerebrovascular injury: although bradyarrhythmia during exercise treadmill testing is typically attributed to cardioinhibitory vasovagal syncope, concurrent pontine infarction likely disrupted brainstem cardio-regulatory centers, sensitizing the patient to vagal hyperactivity. Through systematic analysis of specific arrhythmia-cerebrovascular disease relationships, the final diagnosis identified vasovagal syncope as the primary cause, with cerebral infarction serving as a potential exacerbating factor. This exercise-induced vasovagal syncope complicating stroke provides clinical insights into recognizing overlapping neurovascular-cardiovascular mechanisms during syncope evaluation.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251342060"},"PeriodicalIF":0.6,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}