A case of high grade pancreatic neuroendocrine tumor and the importance of endoscopic ultrasound-guided fine needle biopsy technique.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

SAGE Open Medical Case Reports Pub Date : 2025-06-13 eCollection Date: 2025-01-01 DOI:10.1177/2050313X251347424

Shrey Dalwadi, Zehara Abidi, Avneet Singh, Alexander Garcia, Punitha Shivaprasad, Kunal Dalal

{"title":"A case of high grade pancreatic neuroendocrine tumor and the importance of endoscopic ultrasound-guided fine needle biopsy technique.","authors":"Shrey Dalwadi, Zehara Abidi, Avneet Singh, Alexander Garcia, Punitha Shivaprasad, Kunal Dalal","doi":"10.1177/2050313X251347424","DOIUrl":null,"url":null,"abstract":"<p><p>Pancreatic neuroendocrine tumors are an uncommon group of insidious neoplasms that are often diagnosed in the advanced stages. Diagnosing pancreatic neuroendocrine tumors involves proper biopsy technique and immunohistochemistry, while treatments include targeted therapies and systemic chemotherapy. When diagnosed early, patients with localized disease generally have a positive prognosis. We share a case of a 56-year-old man presenting to the emergency department with acute abdominal pain found to have poorly differentiated pancreatic neuroendocrine tumor with metastasis on repeat endoscopic ultrasound-guided fine needle biopsy. Despite multiple treatment changes, sustained tumor presence led to numerous complications and ultimately patient death. This case highlights the nuances and challenges of diagnosing and treating a rare pancreatic neuroendocrine tumor, such as the importance of biopsy technique.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"13 ","pages":"2050313X251347424"},"PeriodicalIF":0.6000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166229/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SAGE Open Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/2050313X251347424","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Pancreatic neuroendocrine tumors are an uncommon group of insidious neoplasms that are often diagnosed in the advanced stages. Diagnosing pancreatic neuroendocrine tumors involves proper biopsy technique and immunohistochemistry, while treatments include targeted therapies and systemic chemotherapy. When diagnosed early, patients with localized disease generally have a positive prognosis. We share a case of a 56-year-old man presenting to the emergency department with acute abdominal pain found to have poorly differentiated pancreatic neuroendocrine tumor with metastasis on repeat endoscopic ultrasound-guided fine needle biopsy. Despite multiple treatment changes, sustained tumor presence led to numerous complications and ultimately patient death. This case highlights the nuances and challenges of diagnosing and treating a rare pancreatic neuroendocrine tumor, such as the importance of biopsy technique.

查看原文本刊更多论文

高级别胰腺神经内分泌肿瘤1例及超声内镜引导下细针活检技术的重要性。

胰腺神经内分泌肿瘤是一种罕见的隐匿性肿瘤，通常在晚期才被诊断出来。胰腺神经内分泌肿瘤的诊断包括适当的活检技术和免疫组织化学，而治疗包括靶向治疗和全身化疗。如果诊断早期，局限性疾病的患者通常预后良好。我们分享一个病例56岁的男性表现为急性腹痛急诊科发现有低分化胰腺神经内分泌肿瘤并转移的重复内镜超声引导细针活检。尽管多次改变治疗方法，但持续存在的肿瘤导致许多并发症，最终导致患者死亡。本病例强调了诊断和治疗罕见胰腺神经内分泌肿瘤的细微差别和挑战，例如活检技术的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

SAGE Open Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.60

自引率

0.00%

发文量

320

审稿时长

8 weeks

期刊介绍： SAGE Open Medical Case Reports (indexed in PubMed Central) is a peer reviewed, open access journal. It aims to provide a publication home for short case reports and case series, which often do not find a place in traditional primary research journals, but provide key insights into real medical cases that are essential for physicians, and may ultimately help to improve patient outcomes. SAGE Open Medical Case Reports does not limit content due to page budgets or thematic significance. Papers are subject to rigorous peer review and are selected on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, SAGE Open Medical Case Reports facilitates the discovery of the connections between papers, whether within or between disciplines. Case reports can span the full spectrum of medicine across the health sciences in the broadest sense, including: Allergy/Immunology Anaesthesia/Pain Cardiovascular Critical Care/ Emergency Medicine Dentistry Dermatology Diabetes/Endocrinology Epidemiology/Public Health Gastroenterology/Hepatology Geriatrics/Gerontology Haematology Infectious Diseases Mental Health/Psychiatry Nephrology Neurology Nursing Obstetrics/Gynaecology Oncology Ophthalmology Orthopaedics/Rehabilitation/Occupational Therapy Otolaryngology Palliative Medicine Pathology Pharmacoeconomics/health economics Pharmacoepidemiology/Drug safety Psychopharmacology Radiology Respiratory Medicine Rheumatology/ Clinical Immunology Sports Medicine Surgery Toxicology Urology Women''s Health.