Musa Machibya, Nobert Kasinya, Mike Kimambo, Hellen Mram, Lorraine David, Anthony Mulokozi, Zainab Fidaali, Aidan Njau
{"title":"Silent fractured denture ingestion resulting in sigmoid colon perforation: A case report.","authors":"Musa Machibya, Nobert Kasinya, Mike Kimambo, Hellen Mram, Lorraine David, Anthony Mulokozi, Zainab Fidaali, Aidan Njau","doi":"10.1177/2050313X261446406","DOIUrl":"https://doi.org/10.1177/2050313X261446406","url":null,"abstract":"<p><p>Accidental foreign body ingestion is a recognized clinical emergency, particularly among elderly individuals, and may lead to serious gastrointestinal complications. Denture ingestion is often silent and may occur due to poor prosthesis fit or fracture. We report a case of a 78-year-old hypertensive woman who presented with a 1-week history of colicky abdominal pain, abdominal distension, constipation, and hematochezia. On examination, she showed signs of generalized peritonitis. Further history revealed that she had unknowingly swallowed a fragment of her broken removable denture several days earlier. Contrast-enhanced computed tomography demonstrated sigmoid colon perforation with a retained foreign body. Emergency exploratory laparotomy confirmed a metallic denture fragment perforating the sigmoid colon. The affected bowel segment was resected, the foreign body removed, and a Hartmann procedure performed. Denture ingestion accounts for a small proportion of gastrointestinal foreign bodies but carries a higher risk of perforation due to sharp components. Early recognition, prompt imaging, and timely surgical intervention are essential for favorable outcomes.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261446406"},"PeriodicalIF":0.6,"publicationDate":"2026-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13129284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parisa Mirzajani, Joel G DeKoven, Anastasia Shamsuyarova
{"title":"Systemic allergic contact dermatitis to nickel presenting predominantly as severe hand dermatitis, successfully controlled with upadacitinib: A case report.","authors":"Parisa Mirzajani, Joel G DeKoven, Anastasia Shamsuyarova","doi":"10.1177/2050313X261446061","DOIUrl":"https://doi.org/10.1177/2050313X261446061","url":null,"abstract":"<p><p>Systemic allergic contact dermatitis to nickel is a challenging condition often presenting as severe hand dermatitis. This case report details the clinical course of a 33-year-old male truck driver with severe hand dermatitis secondary to systemic allergic contact dermatitis to nickel. Despite significant improvement with avoidance, the patient experienced recurrent flares due to ongoing accidental nickel exposure. Upadacitinib provided an effective salvage strategy. The case underlines challenges of managing systemic allergic contact dermatitis.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261446061"},"PeriodicalIF":0.6,"publicationDate":"2026-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13129338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nasal Rosai-Dorfman disease: A case report and review of the literature.","authors":"Jing Yang, Guifeng Yang","doi":"10.1177/2050313X261439212","DOIUrl":"https://doi.org/10.1177/2050313X261439212","url":null,"abstract":"<p><p>Rosai-Dorfman disease is a rare reactive histiocytic proliferation disorder. It is rarely reported in the literature, and its clinical manifestations vary depending on the location of occurrence. The clinical manifestations and imaging features are not characteristic, and the diagnosis mainly relies on pathology and immunohistochemistry. Here, we report a case involving the nasal cavity and paranasal sinuses, which did not exhibit typical symptoms such as painless cervical lymphadenopathy and fever. It could easily have been misdiagnosed as a malignant tumor before surgery. This case did however exhibit typical histopathological features. The patient was treated with surgery combined with hormone therapy and a good clinical outcome was achieved.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261439212"},"PeriodicalIF":0.6,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pancreatitis, panniculitis, polyarthritis syndrome as an initial manifestation of metastatic pancreatic cancer in a breast cancer patient: Importance of early recognition and multidisciplinary management: A case report.","authors":"Sandra Sacks, Bi Mo","doi":"10.1177/2050313X261438390","DOIUrl":"https://doi.org/10.1177/2050313X261438390","url":null,"abstract":"<p><p>Pancreatitis, panniculitis, and polyarthritis syndrome is a rare extrapancreatic triad associated with pancreatic disease and occasionally malignancy. We report a 51-year-old woman with prior hormone receptor-negative, human epidermal growth factor receptor 2-positive breast invasive ductal carcinoma (bilateral mastectomy, adjuvant trastuzumab/pertuzumab, radiation) who developed abrupt painful erythematous nodules of both legs and progressive polyarthralgia of the hands, knees, and ankles. Symptoms were initially treated as inflammatory rheumatic disease with systemic corticosteroids and disease-modifying therapy without benefit, leading to severe functional decline. Imaging later revealed a large hepatic mass; biopsy confirmed metastatic pancreatic acinar cell carcinoma, unifying the presentation as pancreatitis, panniculitis, and polyarthritis syndrome. Coordinated multidisciplinary care, oncology-directed chemotherapy, interventional pain management, and psychological support, improved pain control and mobility. This case adds to the limited pancreatitis, panniculitis, and polyarthritis literature and highlights that absent gastrointestinal symptoms can delay diagnosis; early recognition and collaborative management are essential in malignant pancreatitis, panniculitis, and polyarthritis presentations.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261438390"},"PeriodicalIF":0.6,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Five-year follow-up of conservative management for root fractures in immature permanent tooth post trauma: A case report and literature review.","authors":"Bingna Lin, Cong Liu, Li Chen, Li Zhang","doi":"10.1177/2050313X261441764","DOIUrl":"https://doi.org/10.1177/2050313X261441764","url":null,"abstract":"<p><p>Vertical root fractures in young permanent teeth secondary to dental trauma are rarely documented in the literature. This case report presents an effective conservative management strategy for preserving a young permanent tooth with a cervical vertical root fracture utilizing splinting techniques and long-term follow-up. We report the case of a 6.5-year-old child who presented with a trauma-induced vertical root fracture in the maxillary left central incisor (tooth #21). Over a 5-year follow-up period, successful hard tissue healing and complete root maturation were observed. By detailing the treatment protocol and reviewing relevant literature, this report analyzes the factors influencing vertical root fracture prognosis and highlights the remarkable self-healing capacity of immature teeth. The favorable clinical outcomes demonstrate that conservative management through splinting provides a viable and highly effective therapeutic option for treating vertical root fractures in young permanent dentition.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261441764"},"PeriodicalIF":0.6,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul Karpecki, Brandon Ayres, Eric Donnenfeld, Marjan Farid, Ian Benjamin Gaddie, Preeya K Gupta, Cecelia Koetting, Richard Lindstrom, Selina McGee, Kelly K Nichols, Laura M Periman, Stephen Pflugfelder, Christopher Starr, Nandini Venkateswaran, Elizabeth Yeu
{"title":"Lotilaner ophthalmic solution 0.25% in the treatment of <i>Demodex</i> blepharitis: A case report.","authors":"Paul Karpecki, Brandon Ayres, Eric Donnenfeld, Marjan Farid, Ian Benjamin Gaddie, Preeya K Gupta, Cecelia Koetting, Richard Lindstrom, Selina McGee, Kelly K Nichols, Laura M Periman, Stephen Pflugfelder, Christopher Starr, Nandini Venkateswaran, Elizabeth Yeu","doi":"10.1177/2050313X261443128","DOIUrl":"https://doi.org/10.1177/2050313X261443128","url":null,"abstract":"<p><p><i>Demodex</i> blepharitis is a chronic inflammatory ocular condition caused by <i>Demodex</i> mite infestation of the eyelid that can negatively impact quality of life. Currently, lotilaner ophthalmic solution 0.25% is the only FDA-approved treatment for <i>Demodex</i> blepharitis. The <i>Demodex</i> Expert Panel on Treatment and Eyelid Health has established consensus that lotilaner ophthalmic solution 0.25% should be considered the preferred first-line treatment for <i>Demodex</i> blepharitis. We report a patient who presented with collarettes, the pathognomonic sign of <i>Demodex</i> blepharitis, meibomian gland dysfunction, and poor visual acuity. The patient also had a history of neovascular age-related macular degeneration. Consistent with the <i>Demodex</i> Expert Panel on Treatment and Eyelid Health consensus recommendations, the patient was treated with lotilaner ophthalmic solution 0.25%, lid scrubs, and warm compresses. At the 2-month follow-up, collarettes had resolved, and signs of meibomian gland dysfunction had improved. This case supports the <i>Demodex</i> Expert Panel on Treatment and Eyelid Health recommendation that lotilaner ophthalmic solution 0.25% should be considered the preferred first-line treatment for <i>Demodex</i> blepharitis.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261443128"},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gas embolism associated with a midline catheter in ICU patient: A case report.","authors":"Nicholas Sedillot, Hela Kallel","doi":"10.1177/2050313X261436599","DOIUrl":"https://doi.org/10.1177/2050313X261436599","url":null,"abstract":"<p><p>Midline peripheral intravenous catheters are widely used for long-term peripheral venous access due to ease of placement and a lower complication profile than central lines. To date, gas embolism has not been reported in association with midline catheters. We report the case of a 59-year-old man with COVID-19-related acute respiratory distress syndrome, who developed sudden coma and acute hypoxemia. Bedsides, echography revealed gas embolism in all cardiac chambers, and body-CT scan showed cerebral air emboli and hepatic portal venous gas. The event followed disconnection of a midline catheter infusion set while the patient was spontaneously breathing, hypovolemic and seated. Neurological sequelae persisted despite prompt hyperbaric oxygen therapy and supportive care. This is the first reported case of cerebral gas embolism related to a midline catheter. The case highlights the importance of individualized catheter length, secure line fixation, and risk factor awareness to prevent air embolism, even with peripheral lines.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261436599"},"PeriodicalIF":0.6,"publicationDate":"2026-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelica Cardile, Valeria Zuccalà, Vincenzo Fiorentino, Antonio Ieni, Giovanni Tuccari, Vincenzo Ficarra, Guido Fadda, Maurizio Martini, Pietro Tralongo
{"title":"Penile metastasis from prostate adenocarcinoma: A case report and review of the literature.","authors":"Angelica Cardile, Valeria Zuccalà, Vincenzo Fiorentino, Antonio Ieni, Giovanni Tuccari, Vincenzo Ficarra, Guido Fadda, Maurizio Martini, Pietro Tralongo","doi":"10.1177/2050313X251388198","DOIUrl":"https://doi.org/10.1177/2050313X251388198","url":null,"abstract":"<p><p>Penile metastasis from prostate adenocarcinoma is an exceptionally rare clinical finding, occurring in <0.3% of cases. We report an 85-year-old male with a history of Gleason 4+3 acinar adenocarcinoma, managed conservatively with long-term bicalutamide monotherapy because of his clinical stability. Eight years after diagnosis, he developed a painful, ulcerated glans lesion, surgically excised via glansectomy. Histopathology revealed solid adenocarcinoma with angiolymphatic invasion, high Ki-67 index (20-70%), PSA and CDX2 positivity, and negative CK7/CK20/TTF-1/p63 staining, confirming prostatic origin. Despite the presence of metastasis, disease progression remained indolent, supporting the feasibility of individualized, conservative therapy in selected elderly patients. Literature review highlights venous or lymphatic spread as probable pathways, with prognosis varying widely. This case underscores the importance of considering secondary malignancy in penile lesions, utilizing histopathology and immunohistochemistry for definitive diagnosis, and tailoring management to patient comorbidities and preferences to preserve quality of life.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X251388198"},"PeriodicalIF":0.6,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13100419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral internal carotid artery dissection in a specific unbalanced diet: A case report.","authors":"Kosuke Matsuzono, Masayuki Suzuki, Ayuho Higaki, Katsunari Namba, Shigeru Fujimoto","doi":"10.1177/2050313X261443168","DOIUrl":"https://doi.org/10.1177/2050313X261443168","url":null,"abstract":"<p><p>Recent research has indicated a potential link between specific diets and an increased risk of stroke or cardiovascular disease. In this report, we describe a case involving a 45-year-old male who consumed a nightly diet consisting entirely of convenience store bento or cup noodle ramen for over two decades. After two decades of this diet, he experienced a bilateral internal carotid artery dissection in the petrous and cervical portions in his 40s. This condition resulted in an infarction in the left middle cerebral artery area. After stroke treatment, he was discharged and went home without any sequelae. There was no recurrence of stroke after his diet was adjusted appropriately. Although this is a single case study and we cannot exclude that an unbalanced diet is not the cause, it highlights that certain extreme dietary habits may pose a risk of early-onset artery dissection.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261443168"},"PeriodicalIF":0.6,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13100382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Annular leukocytoclastic vasculitis associated with isolated anti-β2 glycoprotein I immunoglobulin G positivity: A case report.","authors":"Saleha Abdulrahman Aldawsari, Ajlan Hashim Alajlani, Abdulelah Nabil Alkadi, Sadeq Wasil Al-Dandan","doi":"10.1177/2050313X261440652","DOIUrl":"10.1177/2050313X261440652","url":null,"abstract":"<p><p>Vasculitis comprises a spectrum of disorders defined inflammation of the blood vessel walls and is categorized based on vessel size into small-, medium-, and large-vessel vasculitis. The histological characteristics of leukocytoclastic vasculitis include neutrophil infiltration around small cutaneous blood arteries and fibrinoid necrotizing inflammation. Annular morphology is a unique and rare type of leukocytoclastic vasculitis. We report a case of annular leukocytoclastic vasculitis in a 39-year-old Saudi man who presented with scaly annular erythema and targetoid lesion configurations with prominent, raised borders. He was managed with oral prednisolone 40 mg daily as a tapered dosage regimen, in combination with topical mometasone furoate 0.1% cream applied twice daily, resulting in complete resolution of lesions. To the best of our knowledge, this is the first reported case of annular morphology of leukocytoclastic vasculitis with microvascular occlusions in the Middle East.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261440652"},"PeriodicalIF":0.6,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13087318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}