Schizophrenia Research最新文献

{"title":"The role of demographic variables in the effectiveness of metacognitive training for psychosis: A meta-analysis","authors":"Hanna Gelner ,&nbsp;Martyna Krężołek ,&nbsp;Adrianna Aleksandrowicz ,&nbsp;Justyna Piwińska ,&nbsp;Maria Lamarca ,&nbsp;Fabrice Berna ,&nbsp;Vanessa Acuña ,&nbsp;Caroline König ,&nbsp;Steffen Moritz ,&nbsp;PERMEPSY Group ,&nbsp;Susana Ochoa ,&nbsp;Łukasz Gawęda","doi":"10.1016/j.schres.2025.06.017","DOIUrl":"10.1016/j.schres.2025.06.017","url":null,"abstract":"<div><h3>Background</h3><div>Meta-cognitive Training (MCT) is a promising therapeutic approach for schizophrenia. However, the extent to which demographic factors influence its efficacy in reducing psychotic symptoms and cognitive biases, as well as enhancing cognitive insight, needs further examination.</div></div><div><h3>Methods</h3><div>A comprehensive search of databases: PubMed, PsycINFO, Scopus, (2007-November 2024) published only in English was conducted. Thirty-seven studies (81 % randomized, 19 % non-randomized trials) were included. Inclusion criteria were participants with a diagnosis of schizophrenia spectrum or related psychotic disorders, and there were no sex, gender, race, or ethnicity restrictions. We analyzed the influence of demographic factors on the efficacy of MCT, and the meta-regression analyses were conducted for variables including sex, age, duration of illness, and years of education.</div></div><div><h3>Results</h3><div>MCT significantly reduced positive symptoms (d = −0.40; <em>p</em> &lt; 0.001), delusions (d = −0.41; p &lt; 0.001), and improved cognitive insight (d = 0.28; <em>p</em> &lt; 0.05). Women benefit more in cognitive insight in self-reflectiveness scale (d = −0.27; <em>p</em> = 0.05). However, no statistically significant gender differences were observed in other domains. Furthermore, no significant results were observed for other sociodemographic variables under study.</div></div><div><h3>Conclusions</h3><div>MCT has been demonstrated to be an effective therapeutic method in the reduction of symptoms associated with schizophrenia, with the impact of demographic factors being limited. The enhancement of cognitive insight, particularly in the domains of self-reflectiveness and self-confidence, has been demonstrated in women. Future research should consider individual differences, particularly in the context of gender to advance personalized therapeutic approaches and optimize psychological interventions.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 85-97"},"PeriodicalIF":3.6,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“The second I laid eyes on him I knew”: First impressions predict willingness to interact with individuals with schizophrenia","authors":"Tifenn Fauviaux ,&nbsp;Mathilde Parisi ,&nbsp;Ludovic Marin ,&nbsp;Victor Vattier ,&nbsp;Juliette Lozano-Goupil ,&nbsp;Dorra Mrabet ,&nbsp;Delphine Capdevielle ,&nbsp;Stéphane Raffard","doi":"10.1016/j.schres.2025.06.022","DOIUrl":"10.1016/j.schres.2025.06.022","url":null,"abstract":"<div><div>Individuals diagnosed with schizophrenia often experience social interaction deficits, and these difficulties may arise as early as the first encounter. First impressions, formed during initial interactions, are crucial in shaping relationship outcomes. This study explored how first impressions formed during initial encounters influence the quality of social interactions between healthy individuals and those with schizophrenia. We recruited 60 participants, including 20 healthy individuals to serve as interacting partners, 20 individuals diagnosed with schizophrenia, and 20 age and sex-matched healthy controls. Each interacting partner interacted once with an individual diagnosed with schizophrenia and once with a sex- and age-matched healthy control, without knowledge of any diagnosis. Upon arrival at the experiment location, participants were briefly introduced to each other and then asked to rate their first impressions independently. Then, they engaged in four conversational tasks, after which they assessed their willingness to continue interacting—a measure of social interaction quality. Results showed that interacting partners rated individuals with schizophrenia more negatively than healthy controls in both first impressions and willingness to continue interacting. While first impression ratings across all participants significantly predicted willingness to continue interacting, they did not mediate the group differences in willingness scores, suggesting the involvement of additional underlying factors. This study is the first to assess first impressions of individuals with schizophrenia in ecological settings, marking an important step toward understanding the factors contributing to altered first impressions of individuals diagnosed with schizophrenia.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 77-84"},"PeriodicalIF":3.6,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impaired corollary discharge as a predictor of reality monitoring deficits in schizophrenia: Implications for auditory verbal hallucinations","authors":"Subham Samantaray ,&nbsp;Nishant Goyal ,&nbsp;Muralidharan Kesavan ,&nbsp;Ganesan Venkatasubramanian ,&nbsp;Umesh Shreekantiah ,&nbsp;Anushree Bose ,&nbsp;Vanteemar S. Sreeraj ,&nbsp;Manul Das ,&nbsp;Justin Raj ,&nbsp;Sujeet Kumar","doi":"10.1016/j.schres.2025.07.003","DOIUrl":"10.1016/j.schres.2025.07.003","url":null,"abstract":"<div><h3>Background</h3><div>Auditory verbal hallucinations (AVH) in schizophrenia are linked to reality monitoring (RM) impairment in source monitoring tasks. However, little is known about its neurobiological basis. Corollary discharge (CD), a predictive neural mechanism distinguishing self-generated from external stimuli, is hypothesized to underlie these impairments, contributing to the externalization bias of internal thoughts (EB) and the genesis of AVH.</div></div><div><h3>Objective</h3><div>We investigated the relationship between CD signalling and RM deficits in schizophrenia patients (SZP) with persistent AVH.</div></div><div><h3>Methodology</h3><div>Thirty-five SZP and 35 healthy controls (HCs) completed a Talk/Listen paradigm to evaluate CD signalling and an RM task to assess EB and internalization bias (IB). Event-related potentials (ERPs) of auditory N1 amplitudes were recorded, and the Corollary Discharge Index (CDI) was calculated. Old/New Accuracy, EB, and IB were derived from task performance. Regression analysis was conducted to find the predictive relationship between CDI and EB.</div></div><div><h3>Results</h3><div>SZP showed significantly reduced CDI compared to HCs (<em>p</em> &lt; 0.001), primarily due to more negative N1 amplitudes during the Talk condition; no significant difference was observed during Listen. In the RM task, patients exhibited impaired internal source recognition and higher EB (<em>p</em> &lt; 0.001). Regression analysis identified CDI as a significant predictor of EB (R² = 0.128, <em>p</em> = 0.035).</div></div><div><h3>Conclusion</h3><div>Impaired CD signaling contributes, at least partly, to RM deficits and increased EB in schizophrenia, providing insight into the neurobiological underpinnings of AVH. Potential therapeutic interventions targeting AVH may consider correcting these deficits.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 67-76"},"PeriodicalIF":3.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of extra-large scale screening tools for risks of severe mental illnesses using real world healthcare data","authors":"Dianbo Liu ,&nbsp;Karmel W. Choi ,&nbsp;Paulo Lizano ,&nbsp;William Yuan ,&nbsp;Kun-Hsing Yu ,&nbsp;Jordan Smoller ,&nbsp;Isaac Kohane","doi":"10.1016/j.schres.2025.06.024","DOIUrl":"10.1016/j.schres.2025.06.024","url":null,"abstract":"<div><h3>Importance</h3><div>The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3 % of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.</div></div><div><h3>Objective</h3><div>A scalable machine learning based tool was developed to conduct population-level risk screening for SMIs, including schizophrenia, schizoaffective disorders, psychosis, and bipolar disorders, using 1) healthcare insurance claims and 2) electronic health records (EHRs).</div></div><div><h3>Design, setting and participants</h3><div>Data from beneficiaries from a nationwide commercial healthcare insurer with 77.4 million members and data from patients from EHRs from eight academic hospitals based in the U.S. were used. First, the predictive models were constructed and tested using data in case-control cohorts from insurance claims or EHR data. Second, performance of the predictive models across data sources was analyzed. Third, as an illustrative application, the models were further trained to predict risks of SMIs among 18-year old young adults and individuals with substance associated conditions.</div></div><div><h3>Main outcomes and measures</h3><div>Machine learning-based predictive models for SMIs in the general population were built based on insurance claims and EHR.</div></div><div><h3>Results</h3><div>A total of 301,221 patients with SMIs and 2,439,890 control individuals were retrieved from the nationwide health insurance claim database in the U.S. A total of 59,319 patients with SMIs and 297,993 control individuals were retrieved from EHRs spanning eight different hospitals from a major integrated healthcare system in Massachusetts, U.S. The obtained predictive models for SMIs achieved AUCROC of 0.76, specificity of 79.1 % and sensitivity of 61.9 % on an independent test set of an all-age case-control cohort from insurance claim data, and AUCROC of 0.83, specificity of 85.1 % and sensitivity of 66.4 % using EHR data. The fine-tuned models for specific use case scenarios outperformed two rule based benchmark methods when predicting 12-month risk of SMIs among 18-year old young adults but had inferior performance to benchmark methods when predicting SMIs among individuals with substance associated conditions in claims data.</div></div><div><h3>Conclusion</h3><div>Performance of our SMI prediction models constructed using health insurance claims or EHR data suggest feasibility of using real world healthcare data for large scale screening of SMIs in the general population. In addition, our analysis showed cross data source generalizability of machine learning models trained on real world healthcare data. Models constructed from insurance claims appear to be transferable to EHR cohorts and vice versa.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 59-66"},"PeriodicalIF":3.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144571107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimisation and development of new tDCS montages to target the cerebellum in schizophrenia: An electrical current modeling study","authors":"Raquel Guiomar ,&nbsp;Beatriz Catoira ,&nbsp;Paula Castilho ,&nbsp;Chris Baeken ,&nbsp;Ana Ganho-Ávila","doi":"10.1016/j.schres.2025.06.016","DOIUrl":"10.1016/j.schres.2025.06.016","url":null,"abstract":"<div><h3>Background</h3><div>Schizophrenia is a severe psychiatric disorder that affects individuals' cognitive, social, and emotional functioning. Negative symptoms, such as reduced motivation and social withdrawal, are refractory to available treatments and often contribute to poor functioning and quality of life. The cerebellum has been implicated in the pathophysiology of schizophrenia and is a potential target for treatment with non-invasive brain stimulation, for example transcranial direct current stimulation (tDCS). Previous studies have used conventional and high-definition (HD) tDCS montages to target the cerebellum, but these methods have limitations in terms of intensity and focality. Therefore, there is a need to test new cerebellar tDCS montages that optimize both the intensity and focality of the induced electric field.</div><div>Objective: To test two new tDCS montages (PO10Chin and VermisChin) targeting the right posterior cerebellum and vermis and compare their effectiveness with three commonly used cerebellar tDCS montages.</div></div><div><h3>Methods</h3><div>Electric field simulations for five tDCS montages were compared using linear mixed-effects models (LMMs) to assess current intensity and focality in clinical and healthy groups.</div></div><div><h3>Results</h3><div>The PO10Chin montage showed the highest electric current intensity over the right posterior cerebellum, while VermisChin demonstrated high intensity and focality over the vermis. The HD montage exhibited strong intensity but poor focality, with current hotspots mainly in the occipital cortex. Although the healthy control group was associated with higher current intensity, the effect size was small and therefore can be considered negligible, suggesting that the new montages show similar results for both clinical and non-clinical samples.</div></div><div><h3>Conclusion</h3><div>The PO10Chin and VermisChin montages demonstrated highest intensity for right posterior and vermal cerebellum, respectively, compared with the other montages making them promising approaches for targeting the cerebellum in future in vivo studies. Future research should explore the underlying mechanisms, consider safety measures, and evaluate the clinical efficacy of these new montages.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 48-58"},"PeriodicalIF":3.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of an unguided self-help intervention for distressing auditory verbal hallucinations in a heterogenous sample of voice hearers: A randomized controlled trial and explorative cluster analysis","authors":"Laura Fässler ,&nbsp;Steffen Moritz ,&nbsp;Fabienne Schories ,&nbsp;Malek Bajbouj ,&nbsp;Christine Knaevelsrud ,&nbsp;Kerem Böge","doi":"10.1016/j.schres.2025.06.025","DOIUrl":"10.1016/j.schres.2025.06.025","url":null,"abstract":"<div><h3>Objective</h3><div>Clinical care and research need to improve treatment availability for auditory verbal hallucinations (AVH). To provide further evidence, we examined the efficacy of an unguided six-weeks self-help intervention for AVH (MCT_Voice) based on metacognitive training.</div></div><div><h3>Methods</h3><div><em>N</em> = 78 participants with distressing AVH were recruited from clinical and non-clinical settings. We conducted a randomized controlled trial (RCT) that compared the MCT_Voice with a waitlist control group (WL_control), both receiving additional treatment-as-usual. Outcomes were the frequency and distress of AVH, general hallucinatory and psychiatric symptoms, quality of life, and satisfaction with the intervention, following an intention-to-treat (ITT) and per-protocol (PP) principle. Besides, we conducted an explorative cluster analysis to examine subgroups of voice hearers.</div></div><div><h3>Results</h3><div>We found no significant differences between the groups on the frequency and distress of AVH. However, general hallucinatory experiences were significantly reduced in the MCT_Voice compared to the WL_control group in PP-data (<em>F</em>(3,48) = 39.51, <em>p</em> <em>=</em> .038, η²_p = 0.09). No other between group comparisons were significant. The cluster analysis revealed a two-cluster solution with a higher (<em>type 1</em>) and a lower (<em>type 2</em>) symptom burden group, with higher values of clinical and AVH characteristics in cluster 1. Besides, participants in cluster 1 showed significantly greater improvements in AVH compared to cluster 2 (<em>F</em>(1,44) = 7.97; <em>p</em> = .007, η²_p = 0.15).</div></div><div><h3>Conclusion</h3><div>Even though we found no effect of the MCT_Voice on the main outcome, results showed promising outcomes on general hallucinatory experiences in PP data. The identification of AVH clusters could contribute to implement individualized interventions that target specific characteristics and needs of voice hearers.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 36-47"},"PeriodicalIF":3.6,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144548752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse childhood experiences, social functioning deficits and comorbid clinical symptoms among individuals with psychotic disorders: A prospective cohort study","authors":"Sara Abou Chabake ,&nbsp;Isabelle Daigneault ,&nbsp;Charles-Edouard Giguère ,&nbsp;Signature Consortium ,&nbsp;Tania Lecomte","doi":"10.1016/j.schres.2025.06.020","DOIUrl":"10.1016/j.schres.2025.06.020","url":null,"abstract":"<div><div>Adverse Childhood Experiences (ACEs; e.g., sexual and physical abuse, exposure to intimate partner violence) are significant risk factors for developing psychosis and persistent psychotic disorders. Limited research has explored the influence of ACEs on the social functioning and comorbid clinical symptoms (depression, anxiety, and substance misuse) of individuals with psychotic disorders (PD) throughout their illness. This prospective cohort study aimed to determine whether the social functioning deficits and comorbid clinical symptoms of people with psychotic disorders varied over one year after psychiatric hospital admission, depending on the presence or absence of ACEs. Between 2012 and 2020, data were gathered by the Signature Biobank of the <em>Institut Universitaire en Santé Mentale de Montréal</em> for individuals hospitalized for psychotic symptoms (<em>N</em> = 970). Self-reported measures were used at four measurement times. Findings from the mixed-effects model for repeated measures revealed lower global social functioning and higher scores of depression, anxiety, and substance misuse over time for the psychotic disorder group with ACEs compared to the psychotic disorder group without ACEs. Implications for psychosis treatment with trauma-informed adaptations are discussed.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 27-35"},"PeriodicalIF":3.6,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144548751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased excitation enhances the sound-induced flash illusion by impairing multisensory causal inference in the schizophrenia spectrum","authors":"Renato Paredes ,&nbsp;Francesca Ferri ,&nbsp;Vincenzo Romei ,&nbsp;Peggy Seriès","doi":"10.1016/j.schres.2025.06.007","DOIUrl":"10.1016/j.schres.2025.06.007","url":null,"abstract":"<div><div>The spectrum of schizophrenia is characterised by an altered sense of self with known impairments in tactile sensitivity, proprioception, body-self boundaries, and self-recognition. These are thought to be produced by failures in multisensory integration mechanisms, commonly observed as enlarged temporal binding windows during audiovisual illusion tasks. To our knowledge, there is an absence of computational explanations for multisensory integration deficits in patients with schizophrenia and individuals with high schizotypy, particularly at the neurobiological level. We implemented a multisensory causal inference network to reproduce the responses of individuals who scored low in schizotypy in a simulated double flash illusion task. Next, we explored the effects of recurrent excitation, cross-modal and feedback weights, and synaptic density on the visual illusory responses of the network. Using quantitative fitting to empirical data, we found that an increase in the weights of the recurrent excitatory connectivity in the network enlarges the temporal binding window and increases the overall proneness to experience the illusion, matching the responses of individuals scoring high in schizotypy. Moreover, we found that an increase in excitation increases the probability of inferring a common cause from the stimuli. We propose an E/I imbalance account of reduced temporal discrimination in the SCZ spectrum and discuss possible links with Bayesian theories of schizophrenia. We highlight the importance of adopting a multisensory causal inference perspective to address body-related symptomatology of schizophrenia.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 1-10"},"PeriodicalIF":3.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144535868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of a psychosis consultation service: Early lessons from a statewide initiative","authors":"Sümeyra N. Tayfur,&nbsp;Laura A. Yoviene Sykes,&nbsp;Cenk Tek,&nbsp;Vinod H. Srihari","doi":"10.1016/j.schres.2025.06.019","DOIUrl":"10.1016/j.schres.2025.06.019","url":null,"abstract":"<div><div>In February 2024, the Program for Specialized Treatment Early in Psychosis (STEP) in Connecticut launched the STEP Learning Collaborative (STEP-LC), a statewide learning health system. As part of this initiative, STEP-LC introduced a free consultation service to support clinicians, administrators, and healthcare leaders in the continuing care of young people with recent-onset psychosis (ages 16–35). As the only coordinated specialty care (CSC) clinic in the state offering this provider-to-provider service, STEP aims to address clinical and systemic challenges by providing expert guidance on medication management, psychotherapy, family engagement, and program development. Consultations are requested through a brief online form publicly available on the STEP-LC <span><span>website</span><svg><path></path></svg></span>. Experts at STEP aim to respond within one business day to initiate discussions regarding the identified case. The service is designed to be flexible, offering one-on-one meetings, integrating consultations into existing team meetings at the requesters' agencies, and allowing outside organizations to observe STEP operations. To date, 26 consultations have been completed: 24 within the state and 2 from out-of-state. Within-state requests primarily involved direct clinical issues, such as treatment planning, transitions of care, and family support strategies. Out-of-state consultations focused on broader systemic needs, including the development of new early psychosis programs and collaborative networks. Feedback from consultees highlights the value of the service in enhancing the quality and accessibility of psychosis care. This initiative underscores the importance of leveraging specialized expertise to support both individual and systemic efforts in early psychosis intervention.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"282 ","pages":"Pages 198-202"},"PeriodicalIF":3.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food and nutrition insecurity among individuals with schizophrenia and related psychotic disorders","authors":"Michael T. Compton","doi":"10.1016/j.schres.2025.06.023","DOIUrl":"10.1016/j.schres.2025.06.023","url":null,"abstract":"<div><div>Food insecurity is a prominent, modifiable driver of poor diet quality and medical comorbidities like overweight/obesity, hypertension, metabolic syndrome, type 2 diabetes, and cardiovascular disease. High rates of these conditions among individuals with psychotic disorders are due to complex factors, including poor access to healthy food. Those with psychotic disorders and other forms of serious mental illnesses have a very high prevalence of food insecurity (i.e., being without reliable access to enough food) and nutrition insecurity (i.e., poor access to nutritious food in particular). Access to healthy food and diet quality are not equally distributed; some groups face much greater disadvantages than others. Individuals with psychotic disorders should be screened for food and nutrition insecurity, evaluated further in the context of a positive screening, and referred to local resources where food-related needs can be addressed.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"283 ","pages":"Pages 21-26"},"PeriodicalIF":3.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144548753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}