{"title":"[A viral splenic rupture].","authors":"Stéphane Peters, Cristian Iloaie, Fabien Guérisse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 28-year-old patient is admitted in the emergency department for management of localized pain in the left hypochondrium and left flank that appeared 48 hours before his visit to the emergency room. At the same time, the patient describes the presence of fever, odynophagia and myalgia present for 8 days. The clinical examination highlights the presence of multiple upper cervical and submandibular bilateral and soft adenopathies of about 1.5 cm. There is also an abdominal defense at the level of the left hypochondrium and the left flank. The exploration will attest the presence of a primary EBV infection associated with a splenic rupture complicated by hemoperitoneum without hemodynamic repercussions. This clinical case illustrates the presence of a rare and potentially fatal complication following a very common disease, infectious mononucleosis.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 4","pages":"181-182"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9678968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Atypical presentation of a polyp of Killian].","authors":"Mehdi Ferjaoui, Emna Bergaoui, Jamel Koubaa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The antrochoanal polyp or polyp of Killian is a benign nasal tumour that arises from the maxillary sinus. The polyp originating from the middle turbinate is an entity rarely described in the literature. We report here a rare case of Killian polyp originating from the middle turbinate which was explored by computed tomography and magnetic resonance imaging of the facial bone. The polyp was removed by an endoscopic surgical technique. The extraction was made from the oropharynx. Preoperative recognition of these anatomical variations is particularly important to avoid intraoperative surprises.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 4","pages":"196-198"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9678969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Anti-obesity drugs : from previous disappointments to new hopes].","authors":"André Scheen, Jenny De Flines, Nicolas Paquot","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Both physicians and patients dream of an efficacious and safe pharmacological approach to treat obesity. Unfortunately, most anti-obesity drugs prescribed since the fifties were associated with an unfavourable risk profile that led to numerous withdrawals. Medications issued from pharmaco-chemistry that mainly target brain amines to reduce appetite have been abandoned because of potential cardiovascular and neuropsychiatric toxicities. More recently, biological medications emerged, especially GLP-1 (Glucagon-Like Peptide-1) receptor agonists, well-known to manage type 2 diabetes and now recommended at higher doses for the treatment of obesity (liraglutide, semaglutide). A dual agonist that targets both GLP-1 and GIP (Glucose-dependent Insulinotropic Polypeptide) receptors (tirzepatide) appears to be even more potent as glucose-lowering agent and is currently tested as an anti-obesity agent. Many other pharmacological approaches are currently investigated but they should not mask the importance of life-style measurements.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"147-152"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9491924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A common dilemma in medicine : fortuitous association or causal relationship ?]","authors":"André Scheen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Making the differential diagnosis between a simple fortuitous association and a true causal relationship is a challenge commonly encountered not only in epidemiology, but also in clinical practice. The nine criteria supporting a causal relationship published by Bradford-Hill in 1965 remain relevant, even if some amendments were proposed in recent years. The present clinical scenario illustrates this problem by analyzing the controversies concerning the relationships between hypercholesterolemia (LDL) and coronary heart disease on the one hand and between statin therapy and myalgia on the other hand.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"173-178"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9491925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Weerts, Mathieu Lempereur, Philippe Léonard, Patrizio Lancellotti
{"title":"[Facing COVID-19 : myocarditis following vaccination with mRNA SARS-CoV-2].","authors":"Victor Weerts, Mathieu Lempereur, Philippe Léonard, Patrizio Lancellotti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Myocarditis is a relatively uncommon and underdiagnosed heart disease. Its clinical presentation is variable, from pauci-symptomatic to a symptomatology of sudden chest pain. The latter mimics cardiological emergencies and must therefore be quickly discerned to guide the rest of the treatment. The treatment is mainly supportive and rarely directly etiological. This is a pathology that resurfaced with the onset of the COVID-19 pandemic but also with vaccination. We present here the case of a mRNA SARS-CoV-2 vaccine-induced myocarditis whose clinical manifestations impose a rapid decision concerning the differential diagnosis with an acute coronary syndrome.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"141-146"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9491918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Complex congenital heart disease : about a case of Noonan syndrome].","authors":"Samia Magotteaux, Nesrine Farhat, Adeline Jacquinet, Marie-Christine Seghaye","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present the case of a young girl in whom pre-natal echocardiography showed double outlet right ventricle associated with severe infundibular- and pulmonary valve stenosis. The genetic testing has shown a mutation on the LZTR1 gene, which confirms the diagnosis of a Noonan Syndrome, also present in the mother and an elder sister. The infant was born premature at 34 weeks and 5 days of gestational age. During the neonatal period, feeding difficulties are noted linked to oral aversion and exacerbated by difficulties in the mother-child bond. At 1 month of age, the child presented hypoxic spells caused by the infundibular stenosis which required emergency aorto-pulmonary anastomosis placement ensuring sufficient pulmonary blood flow. This anastomosis needed to be replaced by a larger one at 9th month of age. The child is now 4 years old and has undergone a complete surgical correction. The multidisciplinary management englobes not only follow up in cardiology, genetics, neurology, ophthalmology and hematology but also feeding support and psychomotor development support. The socio-economic precariousness of the family leads to a constant assistance to allow the best possible development of the child.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"130-136"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9507298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Jaumotte, Zakaria Mokhtari, Laurine Deruyck, Maxime Le Clercq, Yves Gilon
{"title":"[How I treat... a fracture of the coronoid apophysis, choice between conservative attitude and surgical treatment].","authors":"Martin Jaumotte, Zakaria Mokhtari, Laurine Deruyck, Maxime Le Clercq, Yves Gilon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fractures of the coronoid process are the rarest mandibular fractures and are mostly associated with other maxillofacial fractures. They are most often encountered in trauma. The CT-scanner is the gold standard for locating and characterizing this lesion. Although the diagnosis is made radiologically, clinical examination may reveal various symptoms specific to this fracture, which may appear frustrated when other facial fractures are associated. In most cases, conservative treatment by intermaxillary fixation is preferred. However, in specific cases, surgical intervention such as coronoidectomy or open reduction with osteosynthesis is indicated. The type of fracture, its location, the delay before its management, the clinic and the presence of associated fractures guide the therapeutic attitude. Surgical management must be followed by early and intensive physiotherapy to avoid zygomatico-coronoid ankylosis, the main complication of this fracture.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"124-129"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9517606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maxime Boulanger, Philippe Léonard, Sabrina Egrek, Olivier Detry, Marie-Pierre Hayette
{"title":"[Evaluation of the knowledge on alveolar echinococcosis among general practitioners in the province of Liege : impact of a formative intervention].","authors":"Maxime Boulanger, Philippe Léonard, Sabrina Egrek, Olivier Detry, Marie-Pierre Hayette","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Alveolar echinococcosis is an indigenouszoonosis caused by the growth of the larval stage of a small tapeworm, Echinococcus multilocularis. Despite a low incidence in Belgium, with about 10 cases on average recorded per year, this parasitosis poses a real public health problem because it often remains difficult to diagnose and is potentially fatal in the absence of treatment. General practitioners are on the frontline, but they do not always know enough about the disease, which causes a delay in the diagnosis and impacts the prognosis. The present study aims to assess the level of knowledge of alveolar echinococcosis among general practitioners in the province of Liège via a questionnaire, on the one hand, and to increase their level of knowledge via a formative intervention using a video capsule, on the other hand. We have performed a randomized controlled experimental study, which showed that general practitioners in the province of Liège have limited knowledge on alveolar echinococcosis. This mainly concerns symptomatology, diagnostic tools and treatment. The formative intervention carried out allowed increasing their level of knowledge about this disease.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"153-159"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9193292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amine Benmoussa, I Moukrim, N Khoubila, S Cherkaoui, M Lmchaheb, M Qachouh, M Rachid, A Madani
{"title":"[Primary renal marginal zone B lymphoma].","authors":"Amine Benmoussa, I Moukrim, N Khoubila, S Cherkaoui, M Lmchaheb, M Qachouh, M Rachid, A Madani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary renal marginal zone B lymphoma is extremely rare. The renal involvement by the lymphoma is most often a manifestation of a disseminated disease. We report the case of a 53-year-old patient who presented lower back pain and kidney failure. The renal biopsy showed a marginal zone B lymphoma type MALT and the PET scan showed bilateral renal involvement. A treatment based on rituximab combined with chemotherapy (cyclophosphamide, prednisone and oncovin) was started with good outcome.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"121-123"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9507293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael D'Atria, Parvesh Gowreesunker, Nicolas Samalea
{"title":"[Hemorrhagic shock secondary to splenic injury after colonoscopy].","authors":"Michael D'Atria, Parvesh Gowreesunker, Nicolas Samalea","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Colonoscopy is a common procedure but splenic injury after colonoscopy is quite uncommon. Its presentation can be atypical and its outcome possibly fatal. In this case report, we highlight the importance of prompt recognition of the incident, by discussing etiological factors, risk factors and also by underlining the significance of maintaining a clinical awareness of this complication.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 3","pages":"137-140"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9491923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}