SAGE Open Medicine最新文献

{"title":"Enhancing job satisfaction measurement tool in healthcare settings: Insights from a University Hospital in Vietnam.","authors":"Nguyen Duc Thanh, Pham Quynh Anh, Pham Thi Huyen Chang, Ha Thi Minh Nguyet, Chu Huyen Xiem, Pham Van Hung, Le Bao Chau","doi":"10.1177/20503121241292676","DOIUrl":"10.1177/20503121241292676","url":null,"abstract":"<p><strong>Background and objectives: </strong>Extensive scrutiny within organizational research has positioned job satisfaction as a pivotal factor contingent upon organizational contexts. Our study aimed to refine job satisfaction measurement tools for diverse healthcare settings using insights from a university hospital in Vietnam, enhancing the validity and applicability of these instruments.</p><p><strong>Methods: </strong>The procedure for the contextualization of a job satisfaction measurement tool was established encompassing six key steps: (1) Developing, selecting, or modifying the questionnaire; (2) Assessing face validity; (3) Ensuring content validity; (4) Designing the research for field testing; (5) Assessing the tool reliability and validity; and (6) Assessing discriminant validity between two tools. This procedure served as the foundation for a cross-sectional study involving 216 healthcare staff at a university hospital in Vietnam.</p><p><strong>Results: </strong>The modified tool, comprising 35 items (6 fewer than the original 41-item reference tool), was derived through evaluations of face, content, and construct validity, conducted with 216 healthcare staff. The validity of the modified tool was subsequently confirmed through Confirmatory Factor Analysis, demonstrating favorable fit indices for the job satisfaction item, including a Chi-square/degrees of freedom ratio of 3.15, Comparative Fit Index of 0.86, Tucker Lewis Index of 0.85, and Root Mean Squared Error of Approximation of 0.1. Additionally, the modified tool exhibited a high Cronbach's alpha of 0.97, a good convergence ranged from 0.4 to 0.6 and a good divergence with the maximum shared variance values were lower than the corresponding average variance extracted values. The job satisfaction scores obtained using the modified tool surpassed significantly those of the original reference tool (<i>p</i> < 0.01), with percentages of 52.7% and 43.1%, respectively.</p><p><strong>Conclusion: </strong>This contextualization procedure has been demonstrated to be both feasible, practical and yielded valid and reliable results, thus recommending its adoption in other healthcare settings along with further validation and adaptation, including rural settings.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological assessment of diabetes mellitus in children of Ukraine during the last 20 years (2002-2021) of peacetime.","authors":"I O Mityuryayeva-Korniyko, O P Volosovets, S P Kryvopustov, Ie A Burlaka, M O Polukhina, T A Shevchenko, M P Nechayev, I V Kovalchuk, Y M Kryvonos","doi":"10.1177/20503121241255213","DOIUrl":"10.1177/20503121241255213","url":null,"abstract":"<p><strong>Objectives: </strong>Nowadays, there is a global trend towards an increase in the prevalence and incidence of diabetes mellitus, including among children, which is a significant health problem in many countries. The analysis of data on diabetes among children is important for training medical personnel and planning preventive measures. The aim is to determine the trends in the prevalence and incidence of diabetes mellitus, as well as the gender and age structure among the paediatric population of different regions of Ukraine over the last 20 years (2002-2021) of peacetime.</p><p><strong>Methods: </strong>The results of statistical evaluation and epidemiological analysis of the data of the Centre for Medical Statistics of the Ministry of Health of Ukraine on the prevalence and incidence of diabetes mellitus among children during 2002-2021 are presented. Statistical processing of the results was carried out using MS Excel (Microsoft Corporation, USA), XLSTAT-Pro (Addinsoft, USA).</p><p><strong>Results: </strong>According to the Ministry of Health of Ukraine, as of 2021, 11,193 children aged 0-17 years inclusive with diabetes mellitus were registered, which is 15.0 cases per 10 thousand of the relevant population. Compared to 2002, the prevalence and incidence rates increased by 93% and 80%, respectively; the fastest rates were among children aged 0-6 years, and the lowest among adolescents aged 15-17 years. In 2021, the highest incidence of diabetes among infants over the past 15 years was recorded (0.05 per 1000 of the relevant population).</p><p><strong>Conclusions: </strong>In Ukraine, over the past 20 years (2002-2021) of peacetime, there has been an annual gradual increase in the prevalence and incidence of diabetes mellitus among children in all age groups with gender balance, which generally corresponds to the global trend.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a combination of dyslipidemia and hypertension on the glycemic control of patients with type 2 diabetes mellitus: a cross-sectional study.","authors":"Heqing Lou, Yixue Jiang, Chunrong Xu, Zong-Mei Dong, De Liu, Cheng Qiao, Pan Zhang","doi":"10.1177/20503121241265066","DOIUrl":"10.1177/20503121241265066","url":null,"abstract":"<p><strong>Objectives: </strong>Both dyslipidemia and hypertension contribute to poor glycemic control in patients with type 2 diabetes mellitus, but the combined effect of dyslipidemia and hypertension on glycemic control in patients with type 2 diabetes mellitus has not been evaluated. The aim of this study was to analyze the interaction effect between dyslipidemia and hypertension on glycemic control in patients with type 2 diabetes mellitus.</p><p><strong>Methods: </strong>A total of 2485 patients with type 2 diabetes mellitus were selected from the Xuzhou community of China by multi-stage cluster random sampling for a cross-sectional survey. Their glycated hemoglobin, dyslipidemia, and hypertension were assessed, and the interaction effects between dyslipidemia and hypertension on glycemic control were analyzed using relative excess risk due to the interaction, the synergy index, and the attributable proportion of the additive interaction.</p><p><strong>Results: </strong>Of the participants, 62.13% (1544/2485) had dyslipidemia and 55.01% (1367/2485) had hypertension. Of the participants, 76.66% (1905/2485) who had both dyslipidemia and hypertension also had poor glycemic control. The prevalence of poor glycemic control was higher in those with both dyslipidemia and hypertension (odds ratio 2.735, 95% confidence interval 2.117-3.532; <i>p</i> < 0.001) compared with those who had normal blood lipids and without hypertension, after adjustment for confounders. The relative excess risk due to the interaction, the attributable proportion, and the synergy index were 1.077 (95% confidence interval 0.558-1.596), 2.637 (95% confidence interval 1.268-4.006), and 0.394 (95% confidence interval 0.230-0.558), respectively, for the interaction between dyslipidemia and hypertension.</p><p><strong>Conclusions: </strong>Dyslipidemia and hypertension have an additive interaction on poor glycemic control in patients with type 2 diabetes mellitus.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Software-driven chronic disease management: Algorithm design and implementation in a community-based blood pressure control pilot.","authors":"Rahul C Deo, Rebecca Smith, Calum A MacRae, Esha Price, Horace Sheffield, Rahul Patel","doi":"10.1177/20503121241284025","DOIUrl":"10.1177/20503121241284025","url":null,"abstract":"<p><strong>Background: </strong>Optimal guideline-directed medical therapy is rarely attained in practice, resulting in inadequate control of diseases such as hypertension, with poorer results in under-resourced communities. Technology, including artificial intelligence-driven decision support and software-driven workflow transformation, can potentially improve disease outcomes at a reduced cost, although it must be integrated with a holistic approach.</p><p><strong>Methods: </strong>We describe the design of a software platform that enables rapid iterative remote management of >20 conditions across cardiac-kidney-metabolic disease. The platform distributes work across a care team of providers and care navigators, automates decision-making, ordering, and documentation, supports rapid incorporation of new evidence, and launches pragmatic trials. We describe software used in a 500-person community-based blood pressure control implemented as a single-arm quality improvement program. The primary endpoint was the proportion of patients meeting the Healthcare Effectiveness Data and Information Set quality measure blood pressure goal (<140/90) at 12 weeks.</p><p><strong>Results: </strong>A total of 1609 patients were screened, 945 (59%) were found to have uncontrolled hypertension, and 512 patients consented to join the program. The average age was 61 ± 11 years; 59% were female, and 99% self-identified as Black. Blood pressure distribution was: 10% Stage 1 (SBP 130-139 mmHg or DBP 80-89 mmHg), 69% Stage 2 (SBP 140-179 mmHg or DBP 90-119 mmHg), and 21% Stage 3 (SBP >180 mmHg or DBP >120 mmHg). Two hundred four patients (39%) proceeded to a provider encounter, and 160 of these (78%) completed the program. The Healthcare Effectiveness Data and Information Set blood pressure goal was achieved in <12 weeks of enrollment for 141 participants (69% of those enrolled, 88% of those who completed the program).</p><p><strong>Conclusion: </strong>Software-driven remote blood pressure is feasible, although strategies to improve patient enrollment will be needed to achieve maximum impact. Future work will be required to compare outcomes to usual care and evaluate concurrent management of multiple cardiac-kidney-metabolic conditions.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TRIB3 as a biomarker of gastric cancer cell sensitivity to chemotherapeutic agents running title: A protective role of TRIB3 on chemotherapy.","authors":"Tein-Ming Yuan, Bang-Hung Liu, Chih-Jou Huang, Yi-Ching Huang, Show-Mei Chuang","doi":"10.1177/20503121241292673","DOIUrl":"10.1177/20503121241292673","url":null,"abstract":"<p><strong>Objectives: </strong>Understanding the role of TRIB3 in cellular chemotherapy responsiveness and survival could facilitate its development as a prognostic marker that could be used to improve chemotherapeutic efficiency against specific tumors. Therefore, the role of TRIB3 to reflect the cytotoxic abilities of chemotherapeutic agents was clarified in the tested gastric cancer cell lines.</p><p><strong>Methods: </strong>We have comprehensively investigated the protein expression of TRIB3 in three gastric cancer cell lines AGS, TMK-1, and MKN-45 cells treated with the anticancer drugs, 5-fluorouracil, cisplatin, and docetaxel. The Cell Count kit-8 was used to evaluate cell viability. Immunoblotting was performed to assay protein levels after drug treatment. Flow cytometry was carried out to evaluate the levels of sub-G1 cell population.</p><p><strong>Results: </strong>Treatment of the tested gastric cancer cell lines dose-dependently decreased cell viability and protein levels of TRIB3 while increasing apoptosis. Overexpression of TRIB3 protects MKN-45 cells from endoplasmic reticulum stress-induced apoptosis but does not influence the induction of autophagy by anticancer drugs. In addition, overexpression of TRIB3 also rescued paroxetine-induced apoptosis and endoplasmic reticulum stress.</p><p><strong>Conclusions: </strong>Our previous and present results indicate that TRIB3 can protect gastric cancer cells against anticancer drug treatment and that downregulating TRIB3 may increase these cells' sensitivity to anticancer drugs. We thus suggest that the capability of anticancer drugs to downregulate TRIB3 can indicate tumors' potential susceptibility to these drugs.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Expression of concern: \"New approaches and procedures for cancer treatment: Current perspectives\".","authors":"","doi":"10.1177/20503121241288169","DOIUrl":"https://doi.org/10.1177/20503121241288169","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1177/20503121211034366.].</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance venography study of venous structures of the transverse-sigmoid sinus region in the Han Chinese population: A cross-sectional study.","authors":"Zibo Zhou, Jinlu Yu","doi":"10.1177/20503121241274244","DOIUrl":"https://doi.org/10.1177/20503121241274244","url":null,"abstract":"<p><strong>Objective: </strong>Venous structures of the transverse-sigmoid sinus region have been insufficiently studied by magnetic resonance venography, especially in the healthy Han Chinese population.</p><p><strong>Methods: </strong>Magnetic resonance venography data were reconstructed. The relevant parameters were recorded. A paired <i>t</i>-test was used to compare the diameters of the inferior petrous sinus at the origin and termination. An unpaired <i>t</i>-test, a chi-squared test or Fisher's exact test was used to compare other data.</p><p><strong>Results: </strong>One hundred healthy participants were included. The average age was 36.6 ± 17.1 years, and the ratio of males to females was 1:1. The development of the transverse-sigmoid sinus had a right-sided predominance in 51% of patients. Statistical analysis revealed significant differences (<i>p</i> < 0.05) in the lengths of bilateral TSs, the lengths of bilateral partial TSs from the torcular to lateral tentorial sinus, the diameters between bilateral TSs at the origin and the lateral tentorial sinus, the diameters between bilateral TS-sigmoid sinus junctions and sigmoid sinus terminations, and the inferior petrous sinus diameters at the origin and termination. Statistical analysis revealed that the right lateral tentorial sinus was more likely to originate from the TS (<i>p</i> < 0.05). Statistical analysis revealed no significant differences (<i>p</i> < 0.05) between transverse-sigmoid sinus development and inferior petrous sinus continuity or between transverse-sigmoid sinus development and inferior petrous sinus continuity and bilateral inferior petrous sinus continuity.</p><p><strong>Conclusions: </strong>This study revealed that the right transverse-sigmoid sinus was predominantly larger in diameter, the torcular Herophili tended to deviate to the right, and the right lateral tentorial sinus tended to drain into the TS. The inferior petrous sinus at the origin was thicker than that at the termination, and the right inferior petrous sinus was thicker than the left inferior petrous sinus. transverse-sigmoid sinus development had no effect on inferior petrous sinus continuity, and there was no difference in inferior petrous sinus continuity between the left and right sides.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurses' knowledge toward hemodialysis vascular access devices: A cross-sectional study in Palestine.","authors":"Sae'd Abu El-Kass, Nisreen Ahmed, Tahreer Kannan, Narmean Abu Shediq, Esraa El Dirani","doi":"10.1177/20503121241264444","DOIUrl":"10.1177/20503121241264444","url":null,"abstract":"<p><strong>Objective: </strong>To assess the nurses' knowledge of vascular access devices for patients undergoing hemodialysis programs in the Gaza Strip, Palestine.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted to assess the nurses' knowledge of hemodialysis vascular access using the convenience sampling technique. The assessment tool comprised 60 items related to the nurses' knowledge and 7 items on demographic characteristics at hemodialysis units in 5 governmental hospitals in the Gaza Strip, between March and June 2023. Statistical analysis of the collected data was performed using SPSS version 22.</p><p><strong>Results: </strong>A total of 65 nurses in hemodialysis units were included. Of the majority of study nurses 71% were male, 21.5% of nurses had fair knowledge, and 78.5% had good knowledge about vascular access devices. The overall average score was more than 70% in all dimensions, which revealed good knowledge about vascular access devices. The study indicated that there was a statistically significant association between nurses' knowledge of vascular access devices and (years of experience in the hemodialysis unit, and received training of nurses).</p><p><strong>Conclusions: </strong>The knowledge of hemodialysis nurses toward vascular access devices for patients undergoing hemodialysis was good. The years in the hemodialysis unit and having training have shown significant association with knowledge among hemodialysis nurses on vascular access devices care. Thus, interventions should focus on providing training for nurses about vascular access devices care in hemodialysis units to improve the comprehensive knowledge of nurses and to maintain patient's health status.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of resilience training in improving the ability to cope with stress and hope of mothers with cancer children.","authors":"Arash Khalili, Mahnaz Khatiban, Sajjad Ebrahimi, Khodayar Oshvandi","doi":"10.1177/20503121241284851","DOIUrl":"10.1177/20503121241284851","url":null,"abstract":"<p><strong>Background: </strong>The present study investigates the effect of resilience training in improving the ability to cope with stress and hope of mothers with cancer children.</p><p><strong>Methods: </strong>In this interventional study, 70 mothers parenting children with cancer were selected as available and randomly classified into the control and experimental groups. The mothers of the two groups completed the parenting stress and hope questionnaire. In the test group, nine sessions of resilience training were held by the researcher for 60 min. One month after the intervention, they were again asked to complete the parenting stress and hope questionnaires. Moreover, in the control group, the mothers completed the parenting stress and hope questionnaires again 2 months later without any intervention.</p><p><strong>Result: </strong>The difference between the average scores of hope and parental stress showed that the mean score of hope in the intervention and control groups increased by about 5.45 and 2.74 units, and the hope variable was improved in both groups. The mean score of parental stress in the intervention group decreased by 39.62 units. However, in the control group, it increased by 2.45 units, and parental stress in this group declined.</p><p><strong>Conclusion: </strong>Resilience training significantly reduced the level of parental stress and increased the level of hope in the mothers of the test group. Therefore, it is recommended to use resilience in reducing the level of parental stress and increasing the hope level of mothers with children with cancer.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility, acceptability, and preliminary effectiveness of implementing a 12-week home-based aerobic and resistance exercise program for breast cancer patients receiving endocrine treatment in Indonesia: A mixed methods study.","authors":"Yufi Kartika Astari, Susanna Hilda Hutajulu, Yayi Suryo Prabandari, Bagas Suryo Bintoro, Rakhmat Ari Wibowo, Mardiah Suci Hardianti, Anggoro Budi Hartopo, Katie M Di Sebastiano, Matthew John Allsop, Shaunna Burke","doi":"10.1177/20503121241272706","DOIUrl":"10.1177/20503121241272706","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the feasibility, acceptability, and preliminary effectiveness of implementing a home-based aerobic and resistance exercise for patients with breast cancer receiving endocrine treatment in Indonesia.</p><p><strong>Methods: </strong>This is a mixed methods study with concurrent design consisting of quantitative single-arm pre-post intervention and qualitative study. We recruited patients with breast cancer (<i>N</i> = 36) receiving endocrine treatment and assigned 12 weeks of home-based pedometer-driven walking and resistance exercises using therapeutic bands. Descriptive statistics were used to assess the feasibility (recruitment, retention, and adherence) and safety. The modified Bruce treadmill test was used to measure predicted aerobic capacity (V̇O₂ peak). Quality of life and fatigue were assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire and fatigue severity scale. Measurements were performed at baseline and post-intervention and analyzed with the paired <i>t</i>-test or Wilcoxon test. Semi-structured interviews and thematic analysis were conducted post-intervention to explore patients' acceptability.</p><p><strong>Results: </strong>The results showed a recruitment rate of 75%, retention rate of 89%, and adherence rates were 53% for aerobic and 78% for resistance exercise. No severe adverse events were reported. Post-intervention interviews identified positive attitudes toward the intervention, with low burden and high perceived benefit. Exercise duration and predicted V̇O₂ peak increased significantly (+1.1 min, <i>p</i> = 0.001 and +2.3 ml/kg/min, <i>p</i> = 0.043), but no significant change was detected for Quality of Life (<i>p</i> > 0.050) or fatigue severity (<i>p</i> = 0.299).</p><p><strong>Conclusions: </strong>A home-based aerobic and resistance exercise was feasible when implemented in the context of routine care in our study population, improving predicted aerobic capacity. Further research is required to understand limited changes to Quality of Life and fatigue and adaptations to support implementation in additional sites in Indonesia.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}