建立基于指南的多学科糖尿病肢体保留计划:临床特征和结果的100天回顾。

IF 2.1 Q2 MEDICINE, GENERAL & INTERNAL
SAGE Open Medicine Pub Date : 2025-09-27 eCollection Date: 2025-01-01 DOI:10.1177/20503121251368698
Jaime Hui Xian Lin, Nicole Yi Xin Lim, Wai Han Hoi, Kwang Wei Tham, Caroline Hoong, Huilin Koh, Melvin Lee, Ye Ni Tham, Shaun Lee, Jo Ann Lim, Faezah Binte Sani, Seri Musfirah Binte Mustafah, Hannah Leong, James Siow, Kaamini Ravindran Pillay, Daniel Seng, Ernest Kwek, Yanli Shao, Sabariah Binte Kaspon, Yuan Teng Cho, Shaun Chan, Pravin Lingam, Sadhana Chandrasekar, Zhiwen Joseph Lo
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引用次数: 0

摘要

目标:新加坡一家新成立的医院推出了一项开创性的多学科糖尿病足项目,为糖尿病足溃疡患者提供全面的护理。本研究评估了多学科糖尿病残肢抢救方案的早期结果。在手术的前100天,糖尿病足项目管理了106名患者。方法:采用描述性统计分析方法,对随访100天的临床特征和结局进行评价。结果:患者以马来人(46.2%)和男性(61.3%)居多,中位年龄63.5岁。大多数患者患有长期糖尿病和血糖控制不良(77.8%),导致糖尿病相关并发症发生率高。骨髓炎占18.3%,坏疽占11.7%。在106例患者中,61.3%需要住院治疗,25.5%进行了血运重建,34.9%进行了糖尿病足溃疡相关手术。根据伤口、缺血和足部感染的12个月风险分层,近30%的患者处于下肢大截肢的中至高风险。15.1%的患者发生轻度下肢截肢,4.7%的患者需要进行重度下肢截肢。30天死亡率为3.8%,平均住院时间为15.7天。从入院到血运重建时间为4.4天,到糖尿病足溃疡相关手术时间为4.2天。在100天的随访中,34.8%的患者伤口愈合,愈合时间为63.2天。结论:我们基于指南的多学科糖尿病残肢保留方案显示出良好的残肢保留结果,尽管预测截肢风险很高。该方案的早期成果突出了早期医疗优化、感染控制、血运重建和积极伤口护理的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Establishing guidelines-based multidisciplinary diabetic limb salvage programme: A 100-day review of clinical characteristics and outcomes.

Objectives: A newly established hospital in Singapore has introduced a pioneering multidisciplinary diabetic foot programme to provide comprehensive care for patients with diabetic foot ulcers. This study evaluates the early outcomes of a multidisciplinary diabetic limb salvage programme. Over the first 100 days of operation, the diabetic foot programme managed 106 patients.

Methods: A descriptive statistical analysis was conducted to evaluate clinical characteristics and outcomes at 100 days of follow-up.

Results: The majority of patients were Malay (46.2%) and male (61.3%), with a median age of 63.5 years. Most patients had long-standing diabetes and poor glycaemic control (77.8%), leading to high rates of diabetes-related complications. A total of 18.3% of patients had osteomyelitis, and 11.7% had gangrene. Of the 106 patients, 61.3% required inpatient management, 25.5% underwent revascularisation, and 34.9% had diabetic foot ulcer-related surgeries. According to Wound, Ischaemia and Foot Infection 12-month risk stratification, nearly 30% of patients were at medium to high risk of major lower extremity amputation. Minor lower extremity amputation occurred in 15.1% of patients and 4.7% required major lower extremity amputation. The 30-day mortality rate was 3.8%, and the average length of stay was 15.7 days. The time from admission to revascularisation was 4.4 days, and the time to diabetic foot ulcer-related surgery was 4.2 days. Wound healing was documented in 34.8% of patients at 100 days of follow-up, with a healing time of 63.2 days.

Conclusion: Our guidelines based, multidisciplinary diabetic limb salvage programme demonstrated favourable limb salvage outcomes despite high predicted amputation risks. The early outcomes of this programme highlight the effectiveness of early medical optimisation, infection control, revascularisation and active wound care.

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来源期刊
SAGE Open Medicine
SAGE Open Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.50
自引率
4.30%
发文量
289
审稿时长
12 weeks
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