Scandinavian Cardiovascular Journal最新文献

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Pericardiectomy for constrictive pericarditis: short- and long-term outcomes in Sweden. 缩窄性心包炎的心包切除术;瑞典的短期和长期结果。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-07-20 DOI: 10.1080/14017431.2026.2704942
Sebastian Sartipy, Susanne J Nielsen, Carl Johan Malm, Göran Dellgren, Emma C Hansson
{"title":"Pericardiectomy for constrictive pericarditis: short- and long-term outcomes in Sweden.","authors":"Sebastian Sartipy, Susanne J Nielsen, Carl Johan Malm, Göran Dellgren, Emma C Hansson","doi":"10.1080/14017431.2026.2704942","DOIUrl":"10.1080/14017431.2026.2704942","url":null,"abstract":"<p><strong>Objectives: </strong>Constrictive pericarditis can cause heart failure from restricted diastolic relaxation due to pericardial fibrosis. Pericardiectomy is the only curative treatment. However, evidence regarding factors associated with variation in outcomes after pericardiectomy remains limited. Therefore, we explored short- and long-term outcomes after pericardiectomy for constrictive pericarditis.</p><p><strong>Design: </strong>This nation-wide study included all pericardiectomy procedures for constrictive pericarditis in Sweden 1997-2020 (median follow-up 5.8 (IQR 2.5-10.1) years). Data were collected from the SWEDEHEART registry and two mandatory registries. Short- and long-term survival was analyzed. Long-term mortality was compared with an age and sex matched control group from the Swedish general population (<i>n</i> = 630).</p><p><strong>Results: </strong>We included 175 patients (mean age 59 ± 15 years). Extracorporeal circulation was common (47% of cases), and 26% of patients underwent concomitant cardiac surgery. In the pericardiectomy cohort, 30-day mortality was 5.1%, associated with older age at surgery (<i>p</i> = 0.008). During follow-up, 22% of patients were readmitted because of heart failure, associated with higher age at surgery (<i>p</i> = 0.02) and preoperative atrial fibrillation (<i>p</i> < 0.001). The long-term survival for pericardiectomy patients was poorer compared to the Swedish population controls in univariable analysis (HR 2.55, 95% CI 1.86-3.48). However, after multivariable adjustment for concomitant comorbidities, this association was attenuated (aHR 1.40, 95% CI 0.96-2.05).</p><p><strong>Conclusions: </strong>Pericardiectomy for constrictive pericarditis is a rare procedure and risk of early mortality cannot be overlooked. However, only a low proportion of patients are rehospitalized due to heart failure during follow-up. Pericardiectomy patients show a high frequency of preoperative comorbidities, which appear to play a certain role in the postoperative period.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":" ","pages":"2704942"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148472564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unbiased metabolomics screening for potential biomarkers in patients with In-stent restenosis post percutaneous coronary intervention. 经皮冠状动脉介入治疗后支架内再狭窄患者潜在生物标志物的无偏倚代谢组学筛查。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-01-09 DOI: 10.1080/14017431.2026.2613539
Qikun Yan, Zhiyi Fang, Huan Liu
{"title":"Unbiased metabolomics screening for potential biomarkers in patients with In-stent restenosis post percutaneous coronary intervention.","authors":"Qikun Yan, Zhiyi Fang, Huan Liu","doi":"10.1080/14017431.2026.2613539","DOIUrl":"10.1080/14017431.2026.2613539","url":null,"abstract":"<p><p><i>Purpose.</i> This study utilizes untargeted metabolomics to identify novel serum biomarkers and metabolic pathways linked to in-stent restenosis (ISR). <i>Methods.</i> This retrospective study included patients who underwent percutaneous coronary intervention (PCI) at the Chinese PLA General Hospital between February 2018 and December 2018. Serum metabolites were analyzed using gas chromatography-mass spectrometry (GC-MS). Multivariate analysis was used to identify differential metabolites, and pathway enrichment analysis was performed to explore their biological significance. <i>Results.</i> A total of 61 patients were enrolled, comprising 18 in the ISR group and 43 in the non-ISR group. The ISR group demonstrated a higher prevalence of smoking (50% vs. 21%, <i>p</i> = 0.023), a greater incidence of previous myocardial infarction (72% vs. 37%, <i>p</i> = 0.004), and a lower left ventricular ejection fraction (51% vs. 58%, <i>p</i> = 0.004) compared to the non-ISR group. Seven differential metabolites were identified, with five being upregulated (inosine, myo-inositol, 3-cyanoalanine, monostearin, and glutamine) and two downregulated (biuret and 3-methylcatechol). Pathway enrichment analysis revealed three major metabolic pathways associated with ISR: inositol phosphate metabolism, alanine-aspartate-glutamate metabolism, and the phosphatidylinositol signaling system. Receiver operating characteristic (ROC) analysis indicated that inosine had the highest diagnostic performance [The area under the curve (AUC) = 0.807], followed by myo-inositol (AUC = 0.705) and monostearin (AUC = 0.643). The combined biomarker panel significantly enhanced diagnostic accuracy, achieving an AUC of 0.925, indicating strong predictive potential for ISR. <i>Conclusions.</i> This study identified seven potential serum biomarkers and three metabolic pathways linked to ISR. These findings enhance our understanding of the metabolic mechanisms underlying ISR and could aid in the development of non-invasive diagnostic tools and therapeutic strategies.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":"60 1","pages":"2613539"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145934786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduced radiation and contrast dose using image fusion guidance during endovascular embolization of pulmonary arteriovenous malformations. 应用图像融合引导在肺动静脉畸形血管内栓塞术中降低辐射和造影剂剂量。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-09-02 DOI: 10.1080/14017431.2026.2722550
Hanin Said, Leena Lehti, Nuno V Dias, Johan Elf, Moncef Zarrouk
{"title":"Reduced radiation and contrast dose using image fusion guidance during endovascular embolization of pulmonary arteriovenous malformations.","authors":"Hanin Said, Leena Lehti, Nuno V Dias, Johan Elf, Moncef Zarrouk","doi":"10.1080/14017431.2026.2722550","DOIUrl":"10.1080/14017431.2026.2722550","url":null,"abstract":"<p><p>To evaluate whether image fusion guidance reduces contrast media consumption and radiation exposure during endovascular embolization of pulmonary arteriovenous malformations (PAVM).</p><p><p>A retrospective analysis was performed on 38 endovascular embolization procedures conducted for PAVMs at a tertiary care university hospital between 2009 and 2022. Image fusion guidance was employed in 22 procedures, while the remaining 16 procedures served as a control group. Key metrics for comparison included contrast media usage and radiation exposure, the latter measured indirectly by dose-area product (DAP) and fluoroscopy time.</p><p><p>Significant reductions in both contrast media use and radiation exposure were observed with the implementation of image fusion guidance. The median contrast dose was 0.18 g I/kg in the image fusion group compared to 0.62 g I/kg in the control group (<i>p</i> = 0.001). Similarly, the DAP was 22.4 Gy·cm<sup>2</sup> versus 86.6 Gy·cm<sup>2</sup> (<i>p</i> = 0.04), and fluoroscopy time was 31.2 min compared to 55.7 min (<i>p</i> = 0.04).</p><p><p>In this observational study, image fusion guidance was associated with reduced contrast media usage and radiation exposure during endovascular embolization of PAVMs, without compromising procedural outcomes. These findings provide supportive rather than definitive evidence and warrant confirmation in prospective studies.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":"60 1","pages":"2722550"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of peripheral ultrasound in familial hypercholesterolemia: a systematic review and meta-analysis. 外周超声诊断家族性高胆固醇血症的准确性:一项系统回顾和荟萃分析。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-10-08 DOI: 10.1080/14017431.2026.2735712
Morten Ejlersen, Jakob Knold, Preman Kumarathurai, Axel Diederichsen, Finn Lund Henriksen
{"title":"Diagnostic accuracy of peripheral ultrasound in familial hypercholesterolemia: a systematic review and meta-analysis.","authors":"Morten Ejlersen, Jakob Knold, Preman Kumarathurai, Axel Diederichsen, Finn Lund Henriksen","doi":"10.1080/14017431.2026.2735712","DOIUrl":"10.1080/14017431.2026.2735712","url":null,"abstract":"<p><strong>Background: </strong>Familial hypercholesterolemia is characterized by lifelong exposure to high cholesterol levels and premature atherosclerotic cardiovascular disease. Unequivocal atherosclerosis on imaging reclassifies patients from high to very high risk.</p><p><strong>Objective: </strong>The aim of this systematic review is to evaluate the diagnostic accuracy of carotid ultrasound and femoral ultrasound compared to cardiac computed tomography, for detecting subclinical coronary atherosclerosis in adults with familial hypercholesterolemia with no history or symptoms of atherosclerotic disease.</p><p><strong>Methods: </strong>Studies published in full length in English were identified through a bibliographic database search in eight databases and two trial registers supplemented with backward and forward citation (updated 14 August 2026). Studies were evaluated using the Quality Assessment of Diagnostic Accuracy Studies-2 tool and synthesized using a generalized linear mixed model. The protocol was registered on Open Science Framework, osf.io/89z4a.</p><p><strong>Results: </strong>Thirteen studies were included in the systematic review and three studies in the meta-analysis. Pooled prevalence estimates were 68.5% [62.2;74.5] for carotid plaques, 56.5% [48.3;64.5%] for femoral plaques and a composite measure of coronary artery disease 46.4% [34.4;58.6]. Peripheral ultrasound demonstrated a high sensitivity of 78.9% [51.5;93.0] and low specificity of 32.0% [14.0;57.6].</p><p><strong>Conclusions: </strong>A small amount of very low-quality evidence was identified highlighting the need for further studies to determine the best test-and-treat strategy for this patient group. The current evidence suggests that carotid and femoral ultrasound are unsuitable as replacement tests for cardiac computed tomography but could potentially play a role as triage test for risk stratification.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":" ","pages":"2735712"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for leg wound infection after conventional and no-touch vein harvesting: insights from a multicentre randomised trial. 常规和非接触式静脉采集后腿部伤口感染的危险因素:来自多中心随机试验的见解。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-09-10 DOI: 10.1080/14017431.2026.2730710
Hanna Unosson, Magnus Dalén, Karin Jensevik Eriksson, Henrik Hultkvist, Stefan James, Anders Jeppsson, Hans Henrik Kimose, Ivy Susanne Modrau, Sigurdur Ragnarsson, Ulrik Sartipy, Stefan Thelin, Per Vikholm, Örjan Friberg
{"title":"Risk factors for leg wound infection after conventional and no-touch vein harvesting: insights from a multicentre randomised trial.","authors":"Hanna Unosson, Magnus Dalén, Karin Jensevik Eriksson, Henrik Hultkvist, Stefan James, Anders Jeppsson, Hans Henrik Kimose, Ivy Susanne Modrau, Sigurdur Ragnarsson, Ulrik Sartipy, Stefan Thelin, Per Vikholm, Örjan Friberg","doi":"10.1080/14017431.2026.2730710","DOIUrl":"10.1080/14017431.2026.2730710","url":null,"abstract":"<p><p>ClinicalTrials.gov: ID NCT03501303.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":" ","pages":"2730710"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dysregulated proteins in plasma distinguishing Loeys-Dietz syndrome from other heritable thoracic aortic disease - an explorative study. 血浆蛋白失调可将Loeys-Dietz综合征与其他遗传性胸主动脉疾病区分开来——一项探索性研究
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-07-18 DOI: 10.1080/14017431.2026.2699504
Bjørn Edvard Seim, Yusuf Khan, Margrethe Flesvig Holt, Aleksandra Ratajska, Annika Michelsen, Monica Myklebust Ringseth, Runar Lundblad, Bente Halvorsen, Kirsten Krohg-Sørensen, Liv T N Osnes, Pål Aukrust, Benedicte Paus, John-Peder Escobar Kvitting, Thor Ueland
{"title":"Dysregulated proteins in plasma distinguishing Loeys-Dietz syndrome from other heritable thoracic aortic disease - an explorative study.","authors":"Bjørn Edvard Seim, Yusuf Khan, Margrethe Flesvig Holt, Aleksandra Ratajska, Annika Michelsen, Monica Myklebust Ringseth, Runar Lundblad, Bente Halvorsen, Kirsten Krohg-Sørensen, Liv T N Osnes, Pål Aukrust, Benedicte Paus, John-Peder Escobar Kvitting, Thor Ueland","doi":"10.1080/14017431.2026.2699504","DOIUrl":"10.1080/14017431.2026.2699504","url":null,"abstract":"<p><p><i>Objectives.</i> Thoracic aortic aneurysms (TAAs) are often found in younger individuals and approximately 20% may be associated with heritable thoracic aortic disease (HTAD). There are some data on genomic biomarkers reflecting inflammation and extracellular matrix remodelling in HTAD. However, data that accurately reflect the corresponding protein changes are scarce. Our aim was to quantify proteins by using targeted proteomics in HTAD patients versus healthy controls, to better understand the underlying pathophysiology. <i>Methods</i>. Patients with Loeys-Dietz syndrome (LDS, <i>n</i> = 8), Marfan syndrome (MFS, <i>n</i> = 11), and familial TAA 6, i.e. actin alpha 2 (ACTA2, <i>n</i> = 7) pathogenic variants were recruited at our outpatient clinic. For comparison, blood samples were drawn from 16 healthy controls. Plasma samples were analysed by targeted proteome analysis of 276 proteins using immunoaffinity proteomics. <i>Results</i>. Whereas oncostatin M and pentraxin 3 levels appeared generally higher in HTAD patients, after adjusting for several confounders, significantly higher levels for these markers as well as TNF receptor superfamily member 9 (TNFRSF9), granulysin (GNLY), CD5, vasorin and glycoprotein 1b-α (GP1BA) were only observed in LDS patients compared to healthy controls. Levels of TNFRSF9, GNLY, GP1BA and CD5 correlated positively with Th17 and platelet counts. <i>Conclusions</i>. This discovery study suggests that LDS could represent a particular inflammatory subgroup of HTAD patients potentially reflecting the involvement of Th17 and platelet related mechanisms in the progression of TAA. Larger studies are needed to evaluate if the identified proteins could be used as biomarkers in these patients.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":" ","pages":"2699504"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148397678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Responder analysis of adaptive postural balance cardiac rehabilitation exercise in patients with coronary artery disease and type 2 diabetes: secondary analysis of a randomized trial. 冠状动脉疾病和2型糖尿病患者适应性体位平衡心脏康复运动的应答分析:一项随机试验的二次分析
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-09-28 DOI: 10.1080/14017431.2026.2732500
Deyu Qin, Guangxin Liu, Xinmeng Liu, Jingxiang Zhao, Qian Zhang, Mei Ma
{"title":"Responder analysis of adaptive postural balance cardiac rehabilitation exercise in patients with coronary artery disease and type 2 diabetes: secondary analysis of a randomized trial.","authors":"Deyu Qin, Guangxin Liu, Xinmeng Liu, Jingxiang Zhao, Qian Zhang, Mei Ma","doi":"10.1080/14017431.2026.2732500","DOIUrl":"10.1080/14017431.2026.2732500","url":null,"abstract":"<p><strong>Background: </strong>Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) show variable responses to exercise-based cardiac rehabilitation. We compared metabolic and exercise responder rates after adaptive postural balance cardiac rehabilitation exercise (APBCRE) versus aerobic exercise (AE) and explored baseline factors associated with responder status.</p><p><strong>Methods: </strong>This pre-specified secondary analysis included 167 patients with CAD and T2DM from a randomized trial who completed an 8-week intervention (APBCRE, <i>n</i> = 87; AE, <i>n</i> = 80). Metabolic response was defined as an HbA1c reduction of ≥0.5%, and exercise response as a VO<sub>2</sub>max increase of ≥3.5 mL·kg<sup>-1</sup>·min<sup>-1</sup>. Multivariable logistic regression evaluated associated factors.</p><p><strong>Results: </strong>APBCRE was associated with higher metabolic (48.3% vs 32.5%, <i>p</i> < 0.05) and exercise responder rates (31.0% vs 11.3%, <i>p</i> < 0.01) than AE. APBCRE was independently associated with metabolic response (OR 2.09, 95% CI 1.03-4.25; <i>p</i> = 0.043) and exercise response (OR 3.66, 95% CI 1.55-8.65; <i>p</i> = 0.003). Higher baseline HbA1c was associated with metabolic response (OR 5.04, 95% CI 2.14-11.86; <i>p</i> < 0.001), whereas insulin therapy was inversely associated (OR 0.25, 95% CI 0.07-0.90; <i>p</i> = 0.034). Lower baseline VO<sub>2</sub>max was associated with exercise response (OR 0.84, 95% CI 0.72-0.97; <i>p</i> = 0.016).</p><p><strong>Conclusions: </strong>APBCRE was associated with higher rates of clinically meaningful metabolic and exercise responses than AE. Responder analysis complements conventional outcome assessment and may support individualized cardiac rehabilitation.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":" ","pages":"2732500"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149064296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Large-bore mechanical thrombectomy in intermediate-high and high-risk pulmonary embolism: a retrospective single-centre case series. 大口径机械取栓治疗中、高风险肺栓塞:回顾性单中心病例系列。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-09-11 DOI: 10.1080/14017431.2026.2724613
Simone Juel Dragsbaek, Andreas Overgaard, Henning Mølgaard, Nicolaj Brejnholt Støttrup, Jens Erik Nielsen-Kudsk, Asger Andersen
{"title":"Large-bore mechanical thrombectomy in intermediate-high and high-risk pulmonary embolism: a retrospective single-centre case series.","authors":"Simone Juel Dragsbaek, Andreas Overgaard, Henning Mølgaard, Nicolaj Brejnholt Støttrup, Jens Erik Nielsen-Kudsk, Asger Andersen","doi":"10.1080/14017431.2026.2724613","DOIUrl":"10.1080/14017431.2026.2724613","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical outcomes, efficacy, and safety of catheter-directed large-bore mechanical thrombectomy (LBMT) in patients with intermediate-high-risk and high-risk pulmonary embolism (PE).</p><p><strong>Methods: </strong>This retrospective single-centre case series included 24 patients with acute PE treated with LBMT between August 2021 and November 2024 at Aarhus University Hospital, Denmark. Patients were classified into intermediate-high-risk and high-risk PE. Clinical data, imaging, procedural characteristics, and follow-up outcomes were collected. Primary outcomes included technical success, early clinical improvement, and changes in right ventricular (RV) function. Secondary outcomes comprised 30-day all-cause mortality, intensive care unit admission, procedural complications, and access site events.</p><p><strong>Results: </strong>A total of 24 patients (8 intermediate-high-risk and 16 high-risk PE) were included of which 9 (38%) presented with cardiac arrest and 7 required veno-arterial extracorporeal membrane oxygenation support. LBMT was technically successful in all patients (100%) and early clinical improvement within 48 h was observed in 71%. The RV/left ventricular ratio decreased after LBMT (from 1.8 ± 0.7 to 1.1 ± 0.4, <i>p</i> = 0.0002) and RV function improved. No device-related deaths or cardiac injuries occurred. Three patients (13%) died within 30 days, all of whom presented with cardiac arrest.</p><p><strong>Conclusions: </strong>LBMT was feasible and safe in a real-world cohort of intermediate-high-risk and high-risk PE patients, including those with PE-induced cardiac arrest or contraindications to thrombolysis. The procedure was associated with rapid clinical improvement and favourable hemodynamic outcomes, with a low rate of major complications. These findings support the use of LBMT as an alternative therapeutic option in selected PE patients.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":" ","pages":"2724613"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of a new, decentralized PCI-centre at Nordland Hospital on the quality of STEMI-treatment in the Salten region. Nordland医院新的分散式pci中心对Salten地区stemi治疗质量的影响。
IF 1.4 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-08-21 DOI: 10.1080/14017431.2026.2719261
Christian Abendstein Kjellmo, Ståle Haugset Nymo
{"title":"Effect of a new, decentralized PCI-centre at Nordland Hospital on the quality of STEMI-treatment in the Salten region.","authors":"Christian Abendstein Kjellmo, Ståle Haugset Nymo","doi":"10.1080/14017431.2026.2719261","DOIUrl":"https://doi.org/10.1080/14017431.2026.2719261","url":null,"abstract":"<p><p><i>Background</i>. In February 2020, a percutaneous coronary intervention (PCI) centre was established at Nordland Hospital Bodø (NLSH), offering daytime primary PCI for ST-elevation myocardial infarction (STEMI) patients from the Salten region. Outside opening hours, patients receive thrombolysis and are transported to the University Hospital of Northern Norway in Tromsø (UNN). This study compares process-of-care measures and explores patient outcomes during and outside opening hours in 2020-2024. <i>Methods</i>. We included STEMI patients from the Salten region treated between 1 February 2020 and 31 October 2024. We analysed quality indicators, time to reperfusion, and the exploratory combined endpoint of death within 30 days or ejection fraction (EF) <50% at discharge. <i>Results</i>. Eighty-eight patients were treated at UNN and 81 at NLSH. Treatment met quality targets in 67% during opening hours versus 11% outside opening hours. Median time from ECG to definitive reperfusion with thrombolysis or PCI was 65 min at NLSH versus 160 min at UNN. Among patients who did not receive or respond to thrombolysis, median time to reperfusion was 70 versus 235 min, respectively. Of patients considered for thrombolysis, 46% received thrombolysis with a clinically judged successful response. Longer time to definitive reperfusion was associated with reduced EF at discharge or death within 30 days. <i>Conclusions</i>. When local daytime PCI was available in Bodø, a higher proportion of patients met established quality targets and time to definitive reperfusion was substantially shorter for STEMI-patients from the Salten region. Among patients considered for thrombolysis, 46% received thrombolysis with a clinically judged successful response.</p>","PeriodicalId":21383,"journal":{"name":"Scandinavian Cardiovascular Journal","volume":"60 1","pages":"2719261"},"PeriodicalIF":1.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of acute type A aortic dissection in the Nordic countries. 北欧国家急性A型主动脉夹层的处理。
IF 1 4区 医学
Scandinavian Cardiovascular Journal Pub Date : 2026-12-01 Epub Date: 2026-01-13 DOI: 10.1080/14017431.2026.2613535
Markus Bjurbom, Anders Franco-Cereceda, Christian Olsson
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