Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques最新文献_第6页

[CD5 positive b-lymphocytes in autoimmunity: possible role in Graves' disease]. CD5阳性b淋巴细胞参与自身免疫:可能在Graves病中起作用。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-09-01

A Afeltra, S Russo, C Peri, A Paggi

{"title":"[CD5 positive b-lymphocytes in autoimmunity: possible role in Graves' disease].","authors":"A Afeltra, S Russo, C Peri, A Paggi","doi":"","DOIUrl":"","url":null,"abstract":"CD5+B cells, recently defined B-1a cells, are the main clonotype in the early B cell repertoire and persist throughout adult life. This subset is committed to the production of antibodies, defined \"natural antibodies\", that bind a lot of exogenous antigens, isologous and heterologous serum proteins, tissues and/or self antigens, such as hormones, nucleic acids and phospholipids. These antibodies, mostly IgM, but also IgG and IgA, are polyreactive: their role is likely that of first line of defence against invading microorganisms. Natural antibodies produced by CD5+ B cells may be involved in maintenance functions such as removal of dead cells. Because of their ability to bind self antigens, they may be important in the establishment of autoimmune phenomena. An increase of CD5+ B cells has been demonstrated in some autoimmune disorders. The authors examine the functional characteristics and the expansion of this subset in different diseases. In particular they report the increase in active Graves' disease and discuss the role of CD5+ B lymphocytes in the immune imbalance present in this thyropathy.","PeriodicalId":21382,"journal":{"name":"Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques","volume":"17 5","pages":"167-74"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19739915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hypospadias: complications and adult sequalae]. [尿道下裂:并发症及成人后遗症]。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-09-01

F Ciaraldi, R M Pareo, R Quattropanetti, S Quattropanetti

引用次数: 0

Beta-endorphins ACTH and cortisol in CSF and plasma of HIV infected patients. HIV感染者脑脊液和血浆中β -内啡肽、ACTH和皮质醇的变化。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-09-01

F Spinazzola, C Barletta, G Demartino, F Martini, S Natili, P Noto, F Ferri, G Tossini, G Visco

引用次数: 0

Apnostresstherapy and psychosomatic pathology. 呼吸压力疗法和心身病理学。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

M De Lellis, M Giampietro, M Mastracci, R Cerbo, M Mazza

引用次数: 0

Chemical pleurodesis in the treatment of iterative neoplastic effusion. 化学胸膜融合术治疗复发性肿瘤积液。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

M Batori, L S Gallinaro, R Turano, M Ruggieri, A Forte

引用次数: 0

Circadian rhythms of fibrinogen and antithrombin III in liver cirrhosis. 肝硬化患者纤维蛋白原和抗凝血酶III的昼夜节律。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

P Pasqualetti, R Casale

{"title":"Circadian rhythms of fibrinogen and antithrombin III in liver cirrhosis.","authors":"P Pasqualetti, R Casale","doi":"","DOIUrl":"","url":null,"abstract":"Background: Since acquired deficiencies of fibrinogen and antithrombin III are reported in liver cirrhosis and it is known that their plasma levels fluctuate during the day, the circadian rhythms of plasma fibrinogen and plasma antithrombin III were investigated in patients with compensated and decompensated cirrhosis, compared to healthy controls.Methods: Three groups of subject were considered: (A) 10 healthy controls; (B) 10 patients with compensated liver cirrhosis; (C) 10 patients with decompensated liver cirrhosis. The fibrinogen and antithrombin III levels were determined in blood samples drawn in each studied subject during the span of a whole day and every three hours starting from midnight. The time-related data were analyzed by means of the \"mean-group cosinor\" method.Results: Significant (p < 0.05) circadian rhythms were detected for the two variables in groups A and B, with peaks in the afternoon hours. No significant (p > 0.05) rhythms were found for group C. A significant (p < 0.05) difference was found between the three groups regarding the circadian rhythm of fibrinogen, and between controls and patients with compensated cirrhosis and between compensated and decompensated patients regarding the circadian rhythm of antithrombin III.Conclusions: These data suggest that in healthy subjects the plasma levels of fibrinogen and antithrombin III present daily variations with own circadian rhythms, and that liver cirrhosis is associated with chronobiological circadian changes in the coagulation system, related to the stage of the disease. This progressive derangement could be considered as an index of evolution in the natural history of cirrhosis of the liver.","PeriodicalId":21382,"journal":{"name":"Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques","volume":"17 4","pages":"125-9"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19526609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Appearance of anti-DNA antibodies after treatment with interferon in a patient with chronic type C viral hepatitis]. 慢性丙型病毒性肝炎患者干扰素治疗后出现抗dna抗体。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

P Ballardini, I Cicognani, E Montanari, F Fabbri, R Ferrari, A Del Noce

引用次数: 0

[Acyclovir in the treatment of varicella in immunocompetent children]. [无环鸟苷治疗免疫功能正常儿童水痘]。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

S Catania, C Ajassa, M S Magno, G Berardelli, R Bellagamba, S Tzantzoglou, M Falciano, C M Lanzalone, N Catania

{"title":"[Acyclovir in the treatment of varicella in immunocompetent children].","authors":"S Catania, C Ajassa, M S Magno, G Berardelli, R Bellagamba, S Tzantzoglou, M Falciano, C M Lanzalone, N Catania","doi":"","DOIUrl":"","url":null,"abstract":"We evaluated safety and tolerance of acyclovir ACV per os in immunocompetent children affected by chicken-pox admitted to our department from January 1993 to December 1994. 183 subjects (102 males and 81 females) aged between 0 and 14 years were treated by ACV (80 mg/kg/daily in 4 divided doses): 88 children were treated within 24 hours and 95 subjects within 48 hours from the onset of symptoms. The control group consisted of 83 children (52 males and 31 females) aged between 0 to 14 years. In all patients routine blood-test were performed and in those with respiratory illness Chest-Rx was also done. We evaluated clinical course, degree of eruption, the appearance and kind of complications, duration of hospitalization, the compliance and the potential consequences on specific antibody response. Our results show a faster improvement of clinical symptoms in treated patients with respect to the control group with shortening of the period of the fever, itch and appearance of new vescicles. The percentage of complications was lower in treated than in untreated patients. 16 cases tested for specific antibody response showed protective titers six months after treatment. In conclusion, ACV administered per os within 48 hours from onset of exanthema causes reduction of the period and the degree of general symptoms and exanthema, a lower incidence of complications even if non statistically significant. The drug is safe and well-tolerated.","PeriodicalId":21382,"journal":{"name":"Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques","volume":"17 4","pages":"115-23"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19525323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Immunopathogenic mechanisms in glomerulonephritis]. [肾小球肾炎的免疫致病机制]。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

A Amoroso, L M Cavarretta, F G De Rosa, G M Ferri

引用次数: 0

Stress reactivity in responder and non-responder hypertensives treated with verapamil and enalapril. 维拉帕米和依那普利治疗有反应和无反应高血压患者的应激反应性。

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques Pub Date : 1995-07-01

P Nazzaro, M Manzari, M Merlo, R Triggiani, A M Scarano, A Lasciarrea, N Marella, A Pirrelli

{"title":"Stress reactivity in responder and non-responder hypertensives treated with verapamil and enalapril.","authors":"P Nazzaro, M Manzari, M Merlo, R Triggiani, A M Scarano, A Lasciarrea, N Marella, A Pirrelli","doi":"","DOIUrl":"","url":null,"abstract":"Hypertension was found to be associated with sympathetic overdrive but it is still debated if the antihypertensive agents can differently affect the stress response in hypertensive subjects. Through a psychophysiological study, we evaluated the effect of verapamil (V) and enalapril (E), both as monotherapy and association. Office BP was successfully reduced (< 145/90 mmHg) in 11 patients treated with V (V-Resp) and in 10 patients treated with E (E-Resp). Both the drugs were prescribed in 9 patients (V+E) who did not sufficiently lower their blood pressure (N-Resp) with monotherapy. Patients performed three stressors (color word stroop, cold pressor and handgrip). Extracardiovascular and hemodynamic functions were measured during baseline, stress and recovery periods. The response was evaluated adding the changes occurred in every phase of the psychophysiological session. This was performed before run-in and after any modification of the therapeutic intervention. The emotional arousal (phrontalis muscular contraction, skin conductance, peripheral temperature) was reduced when BP was normal. No change in BP reactivity was found. HR response decreased in V-Resp and cardiac output increased in E-Resp while the vascular reaction was restrained in E-Resp and V-Resp. This was reduced also in N-Resp when they assumed V+E and normalized their arterial pressure. The findings indicate that the sympathetic reactivity may be modified by the therapy. In particular, verapamil restrained the cardiac stress response without lowering the cardiac output and was advantageously associated with enalapril to control the psychophysiological response in more resistant hypertensive patients.","PeriodicalId":21382,"journal":{"name":"Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques","volume":"17 4","pages":"105-13"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19525325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0